| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is fabG [H]
Identifier: 158316253
GI number: 158316253
Start: 5343548
End: 5344303
Strand: Reverse
Name: fabG [H]
Synonym: Franean1_4478
Alternate gene names: 158316253
Gene position: 5344303-5343548 (Counterclockwise)
Preceding gene: 158316254
Following gene: 158316251
Centisome position: 59.5
GC content: 67.86
Gene sequence:
>756_bases ATGGACCTGAGCGGCAGGACGGCGGTGGTCGTCGGAGCGGCGAACGTGGTCGGGCGGGCCTGTGCGCTCCGGTTCGCCCT GGCCGGCGCGCACGTTGTGGTGGCCGACCCCGCCGAAGGTGCGCTGGCCGAGACGGTCGAGGCGATCGCCGCAGTGGCCG GGTCCGTGCAGTCCGCCGTCGTGGACATAACTGATCTGTCCCAGCTGGAGCAACTGTCCGCATCGCTGGCGGGCCGCTAC ATCGGTACCGATATCCTGGTGACGGCGCACTTTGCGATCGACCGGGGTTCCATTGAATTCTCCGCGGTCGAGACGTGGCG CGAGGTCCTCGAGACCAACCTGTTGGGGCCGCTGGTATCGGCCAAAGCCTTCCTGCCCGCCTTGCGTCACTCGGAGCACG CGGCGATCGTGCACATCGGCTCGATCGACGGGCTCCTCGGTAACCCGCAGGTCCCGTCGTACTCCGCCGCCAAGGCGGGC ATGGTGGCACTCACCCGGGTGATGGCGCACGAGTTCGGGAAGTACGGCATCCGGGTCAACTGCGTGGCGCGTGCCGCGGT GGACGACCCGTCCCAGGGCAGCGGGACCAGCCTCATGGAGAAAGTTCTTGACAGTACCGTCCTCAGACGTGCCGCGGCGC CTGACGAAATCGCACAGGTGGTCGCATTTCTTTCGTCTGATGCCGCGGCGTACGTGACTGGTGCCGTTATCCCGGTGGAC GGCGGGCGGGTGGGGCTGACACTGGGGACGGCCTGA
Upstream 100 bases:
>100_bases GTGGGCTGCCCGGCGCGCCCGGAGATCGGTACTGGCCACAGTCACTGCTGCGCCGTGAGGGTCATCGCGCGGGAGCAGTC GGACGGGGAGGTGCGTGCGG
Downstream 100 bases:
>100_bases GCCTGCCGCCCCCGTCAGTCGTCGACCGCCGTGATCCTGGCGGCCTGCCGGGCAACCTCAGGGAAATATCTGCTCGCCGG TGCGCAGGCTGCGGACAAGG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 251; Mature: 251
Protein sequence:
>251_residues MDLSGRTAVVVGAANVVGRACALRFALAGAHVVVADPAEGALAETVEAIAAVAGSVQSAVVDITDLSQLEQLSASLAGRY IGTDILVTAHFAIDRGSIEFSAVETWREVLETNLLGPLVSAKAFLPALRHSEHAAIVHIGSIDGLLGNPQVPSYSAAKAG MVALTRVMAHEFGKYGIRVNCVARAAVDDPSQGSGTSLMEKVLDSTVLRRAAAPDEIAQVVAFLSSDAAAYVTGAVIPVD GGRVGLTLGTA
Sequences:
>Translated_251_residues MDLSGRTAVVVGAANVVGRACALRFALAGAHVVVADPAEGALAETVEAIAAVAGSVQSAVVDITDLSQLEQLSASLAGRY IGTDILVTAHFAIDRGSIEFSAVETWREVLETNLLGPLVSAKAFLPALRHSEHAAIVHIGSIDGLLGNPQVPSYSAAKAG MVALTRVMAHEFGKYGIRVNCVARAAVDDPSQGSGTSLMEKVLDSTVLRRAAAPDEIAQVVAFLSSDAAAYVTGAVIPVD GGRVGLTLGTA >Mature_251_residues MDLSGRTAVVVGAANVVGRACALRFALAGAHVVVADPAEGALAETVEAIAAVAGSVQSAVVDITDLSQLEQLSASLAGRY IGTDILVTAHFAIDRGSIEFSAVETWREVLETNLLGPLVSAKAFLPALRHSEHAAIVHIGSIDGLLGNPQVPSYSAAKAG MVALTRVMAHEFGKYGIRVNCVARAAVDDPSQGSGTSLMEKVLDSTVLRRAAAPDEIAQVVAFLSSDAAAYVTGAVIPVD GGRVGLTLGTA
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=29.1497975708502, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=29.4354838709677, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=30.1960784313725, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=29.4354838709677, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=25.3012048192771, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=31.6666666666667, Blast_Score=81, Evalue=7e-16, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=29.7959183673469, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=32.7956989247312, Blast_Score=74, Evalue=8e-14, Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=29.8245614035088, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=27.4725274725275, Blast_Score=66, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=32.4110671936759, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=30.241935483871, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=30.3643724696356, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=28.1746031746032, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=28.4, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=29.2, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=26.8774703557312, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=30, Blast_Score=72, Evalue=2e-14, Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=26.953125, Blast_Score=66, Evalue=3e-12, Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=31.9672131147541, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=30, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=33.8461538461538, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=28.2258064516129, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=26.3358778625954, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=28.2051282051282, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=29.368029739777, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=24.7967479674797, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=26.9387755102041, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=28.125, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=26.0536398467433, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=25.6, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=27.4509803921569, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=25.1908396946565, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=28.8389513108614, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=27.9850746268657, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=29.9625468164794, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=25.6809338521401, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17561272, Length=262, Percent_Identity=26.7175572519084, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=27.3764258555133, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17565030, Length=255, Percent_Identity=28.2352941176471, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=28.2868525896414, Blast_Score=89, Evalue=5e-19, Organism=Saccharomyces cerevisiae, GI6322861, Length=254, Percent_Identity=25.9842519685039, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=33.1983805668016, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=29.8449612403101, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=27.710843373494, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=28.957528957529, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=28.0487804878049, Blast_Score=88, Evalue=7e-18, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=26.8292682926829, Blast_Score=84, Evalue=6e-17, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=27.4900398406374, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI21357673, Length=190, Percent_Identity=30, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI18859837, Length=244, Percent_Identity=27.0491803278689, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25610; Mature: 25610
Theoretical pI: Translated: 5.03; Mature: 5.03
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLSGRTAVVVGAANVVGRACALRFALAGAHVVVADPAEGALAETVEAIAAVAGSVQSAV CCCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH VDITDLSQLEQLSASLAGRYIGTDILVTAHFAIDRGSIEFSAVETWREVLETNLLGPLVS CCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHH AKAFLPALRHSEHAAIVHIGSIDGLLGNPQVPSYSAAKAGMVALTRVMAHEFGKYGIRVN HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE CVARAAVDDPSQGSGTSLMEKVLDSTVLRRAAAPDEIAQVVAFLSSDAAAYVTGAVIPVD EEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEHEEEEEEEC GGRVGLTLGTA CCEEEEEECCC >Mature Secondary Structure MDLSGRTAVVVGAANVVGRACALRFALAGAHVVVADPAEGALAETVEAIAAVAGSVQSAV CCCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH VDITDLSQLEQLSASLAGRYIGTDILVTAHFAIDRGSIEFSAVETWREVLETNLLGPLVS CCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHH AKAFLPALRHSEHAAIVHIGSIDGLLGNPQVPSYSAAKAGMVALTRVMAHEFGKYGIRVN HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE CVARAAVDDPSQGSGTSLMEKVLDSTVLRRAAAPDEIAQVVAFLSSDAAAYVTGAVIPVD EEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEHEEEEEEEC GGRVGLTLGTA CCEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]