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The map label for this gene is luxQ [H]

Identifier: 158316164

GI number: 158316164

Start: 5233400

End: 5234635

Strand: Reverse

Name: luxQ [H]

Synonym: Franean1_4386

Alternate gene names: 158316164

Gene position: 5234635-5233400 (Counterclockwise)

Preceding gene: 158316165

Following gene: 158316160

Centisome position: 58.28

GC content: 65.29

Gene sequence:

>1236_bases
ATGTCAAGCGACCCGAGGCAGCCGAGCGGAAATCTCGACGCGGCTGTTCTCGAAAACGGGGGGTTCGGTGGCGGTAGCCG
CCGCCGGTACCGGCCCCGCACTCGCGCCGACACCGCGCTCGGCGGGCAGCGGGTCATCGTCGAGCTGCTGGTCCGCCAGT
TCCGCTGTGAGCAGCCGGGCTGTGCGCGGATGTTGTCGCAGAACCCGGCCCGCAACCTCACAGCAAAACAGGTCGAGTAC
GCGCATGTCATCCATTCCGCCGGCGCCGATCTGCTGCAGCTAGTCAACGACATCCTGGACCTGTCCAAAGTCGAGGCCGG
CAAGATGGAAATTCACATGGAGCACGTCTCCCTGCGTGCTCTGCTGGAGGACCTCCGGGCTACCTTCCACCCCATCACGG
AGGAGAATGGTCTCGAGTTCACCGTGGACGTCGCGCCCGACGCGCCGACCGAACTGTTCACCGACTCCCAACGCGTGTCA
CAGGTACTGCGCAACCTGCTGTCGAACGCGGTGAAGTTCACCGAGCAGGGCTGCGTGGAGCTGCGGATACGGACGACCGA
AGGCCCGGACGGGGCCGCGGGGCCCCGCAAGACGGTCGCGTTCTCGGTCGTCGACACCGGCGTCGGAATCGCGGACGACG
ACCTGGACCGGCTCTTCGAGGCCTTCCAGCAAGGGGAAGGCCCCACCAACCGCAGATACGGCGGCACCGGTCTGGGTCTG
TCCATATCCCGCGAGGTCGCGGCGCTGCTCGATGGCGAGCTCCACCTGTCCACCGCCAACCTCGACGAGGAACCGGCCCT
GACGAGAGACGTGACTGAGCCGGTGGAGCGATCACCCATCCCCCAGGCCCCTGCGCATGAAGAGCTACACGGCCGCAAGA
CCCTGGTGATCGACGATGACGTGCGCAACATCTTCGCCATCACCAGCGTCCTCGAGCTCTACGGCATCACCGTGATCTAC
GCATCCGACGGGCGGGAAGGCATCGACACCCTGCTCGCCACCGCTGACGTAGACATCGTCCTCGTCGACGTGATGATGCC
GGAAATGGACGGGTACGCCACCATGACGGCCATCCGCCAGATCCCCCAGTTCGCCACGATTCCGGTCATCGCGGTAACCG
CCAAGGCCATGCCGCATGACCGGGAGAAATGCCTCGCCGCAGGTGCCACCGACTACGTCACGAAACCCGTCGACACCGAA
GAACTCCTCATCCGGATGGAACGACAGATCACCTGA

Upstream 100 bases:

>100_bases
TACCACCACCGGGAACGGGTCCAGTTGACAAATGCCCAACCAGCAACCTGTCAAGTGCCGGATTGGATGGAGACTCGGTT
GTCACGCGATGCTCCTATAG

Downstream 100 bases:

>100_bases
ACGCCGACCGCAGACGCGACCTTTGCTCGGGGCCTGTAAGTAGCACCTGATGACGATCACAACCGACATGACGGACACTC
CCCGCTTGGCCAGCACCCTG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSSDPRQPSGNLDAAVLENGGFGGGSRRRYRPRTRADTALGGQRVIVELLVRQFRCEQPGCARMLSQNPARNLTAKQVEY
AHVIHSAGADLLQLVNDILDLSKVEAGKMEIHMEHVSLRALLEDLRATFHPITEENGLEFTVDVAPDAPTELFTDSQRVS
QVLRNLLSNAVKFTEQGCVELRIRTTEGPDGAAGPRKTVAFSVVDTGVGIADDDLDRLFEAFQQGEGPTNRRYGGTGLGL
SISREVAALLDGELHLSTANLDEEPALTRDVTEPVERSPIPQAPAHEELHGRKTLVIDDDVRNIFAITSVLELYGITVIY
ASDGREGIDTLLATADVDIVLVDVMMPEMDGYATMTAIRQIPQFATIPVIAVTAKAMPHDREKCLAAGATDYVTKPVDTE
ELLIRMERQIT

Sequences:

>Translated_411_residues
MSSDPRQPSGNLDAAVLENGGFGGGSRRRYRPRTRADTALGGQRVIVELLVRQFRCEQPGCARMLSQNPARNLTAKQVEY
AHVIHSAGADLLQLVNDILDLSKVEAGKMEIHMEHVSLRALLEDLRATFHPITEENGLEFTVDVAPDAPTELFTDSQRVS
QVLRNLLSNAVKFTEQGCVELRIRTTEGPDGAAGPRKTVAFSVVDTGVGIADDDLDRLFEAFQQGEGPTNRRYGGTGLGL
SISREVAALLDGELHLSTANLDEEPALTRDVTEPVERSPIPQAPAHEELHGRKTLVIDDDVRNIFAITSVLELYGITVIY
ASDGREGIDTLLATADVDIVLVDVMMPEMDGYATMTAIRQIPQFATIPVIAVTAKAMPHDREKCLAAGATDYVTKPVDTE
ELLIRMERQIT
>Mature_410_residues
SSDPRQPSGNLDAAVLENGGFGGGSRRRYRPRTRADTALGGQRVIVELLVRQFRCEQPGCARMLSQNPARNLTAKQVEYA
HVIHSAGADLLQLVNDILDLSKVEAGKMEIHMEHVSLRALLEDLRATFHPITEENGLEFTVDVAPDAPTELFTDSQRVSQ
VLRNLLSNAVKFTEQGCVELRIRTTEGPDGAAGPRKTVAFSVVDTGVGIADDDLDRLFEAFQQGEGPTNRRYGGTGLGLS
ISREVAALLDGELHLSTANLDEEPALTRDVTEPVERSPIPQAPAHEELHGRKTLVIDDDVRNIFAITSVLELYGITVIYA
SDGREGIDTLLATADVDIVLVDVMMPEMDGYATMTAIRQIPQFATIPVIAVTAKAMPHDREKCLAAGATDYVTKPVDTEE
LLIRMERQIT

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=387, Percent_Identity=28.1653746770026, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI145693157, Length=309, Percent_Identity=29.7734627831715, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789149, Length=186, Percent_Identity=32.258064516129, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788713, Length=333, Percent_Identity=27.9279279279279, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87081816, Length=347, Percent_Identity=29.3948126801153, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788393, Length=165, Percent_Identity=34.5454545454545, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=35.5932203389831, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=33.6206896551724, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=185, Percent_Identity=29.1891891891892, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI2367329, Length=114, Percent_Identity=38.5964912280702, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44860; Mature: 44729

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDPRQPSGNLDAAVLENGGFGGGSRRRYRPRTRADTALGGQRVIVELLVRQFRCEQPG
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCH
CARMLSQNPARNLTAKQVEYAHVIHSAGADLLQLVNDILDLSKVEAGKMEIHMEHVSLRA
HHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
LLEDLRATFHPITEENGLEFTVDVAPDAPTELFTDSQRVSQVLRNLLSNAVKFTEQGCVE
HHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEE
LRIRTTEGPDGAAGPRKTVAFSVVDTGVGIADDDLDRLFEAFQQGEGPTNRRYGGTGLGL
EEEEECCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SISREVAALLDGELHLSTANLDEEPALTRDVTEPVERSPIPQAPAHEELHGRKTLVIDDD
CHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECH
VRNIFAITSVLELYGITVIYASDGREGIDTLLATADVDIVLVDVMMPEMDGYATMTAIRQ
HHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHCCCCEEEEEEHHCCCCCHHHHHHHHH
IPQFATIPVIAVTAKAMPHDREKCLAAGATDYVTKPVDTEELLIRMERQIT
CCCHHCCCCEEEEHHCCCCCHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SSDPRQPSGNLDAAVLENGGFGGGSRRRYRPRTRADTALGGQRVIVELLVRQFRCEQPG
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCH
CARMLSQNPARNLTAKQVEYAHVIHSAGADLLQLVNDILDLSKVEAGKMEIHMEHVSLRA
HHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
LLEDLRATFHPITEENGLEFTVDVAPDAPTELFTDSQRVSQVLRNLLSNAVKFTEQGCVE
HHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEE
LRIRTTEGPDGAAGPRKTVAFSVVDTGVGIADDDLDRLFEAFQQGEGPTNRRYGGTGLGL
EEEEECCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SISREVAALLDGELHLSTANLDEEPALTRDVTEPVERSPIPQAPAHEELHGRKTLVIDDD
CHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECH
VRNIFAITSVLELYGITVIYASDGREGIDTLLATADVDIVLVDVMMPEMDGYATMTAIRQ
HHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHCCCCEEEEEEHHCCCCCHHHHHHHHH
IPQFATIPVIAVTAKAMPHDREKCLAAGATDYVTKPVDTEELLIRMERQIT
CCCHHCCCCEEEEHHCCCCCHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]