Click here to switch to the map view.

The map label for this gene is putA [H]

Identifier: 158316058

GI number: 158316058

Start: 5111805

End: 5115407

Strand: Reverse

Name: putA [H]

Synonym: Franean1_4276

Alternate gene names: 158316058

Gene position: 5115407-5111805 (Counterclockwise)

Preceding gene: 158316061

Following gene: 158316057

Centisome position: 56.95

GC content: 75.13

Gene sequence:

>3603_bases
ATGACCGCGGCAGTGAGCAGTAGCCCGCACGACCTGTCCGACCTGGGCGACGAGGCTGTCGCGCTGGTCCGCCGCTGGGT
CGCCGAGGCGGCGTCCGAGCCGGTGGACCCGGCCGCCGCCCGGCTGGCCGCCGTCCTGCGGGAGCCGGGCGGGCTGGCGT
TCACCGTGCGCTTCGTCGACGGGGTGATCCGTCCGGAGGACCCGCGGGTAGCGGCGCGCAACCTGGCCCGGCTCGCGCCG
TCCGTGCCCGCCTTCCTGCCCTGGTACCTGCGCGGCGCGGTGCGGGCAGGGGGAGTAGCCGGGCCCGTGGTGCCGTGGGT
CGTCGTCCCGGCCGCCCGGCGGGTGCTGCGCCGGATGGTCGGCCACCTCGTCGTCGATGCCACCGACCGCGGGCTCGGAC
GGGCCATCGAGCGGCTGCGCCGGCCCGGCGTCCAGCTGAACATGAACCTGCTGGGGGAGGCCGTCCTCGGTGAGCGGGAG
GCCGCGCGCCGGCTGGCGGGCACGACGGCGCTGCTCGCCCGGGACGACGTCGACCACGTGTCGATCAAGGTGTCGGCGAG
CGTCGCGCCGCACGCCGCCTGGGCCTTCGAGGAGACCGTGGCGCATGTCGTGGAGACGCTGACACCGCTGTTCGAGCAGG
CCATGGCAGCGCGGCCGGCGGAGTCGCGGCCGGCCACGTTCGTCACGTTGGACATGGAGGAGTACCGCGACCTGGACCTG
ACGATCGAGGTGTTCACCACGCTGCTCGACCGGCCGGCCCTGCGGCGCCTGGCGGCCGGGATCGTCCTGCAGGCCTACCT
GCCCGACGCGCTCGGCGCCCTTACCCGCCTGCAGGAGTGGAGCGCGTCCCGGCGGGCGGCCGGCGGTGCCCCGGTCACCG
TACGGCTGGTGAAAGGCGCGAACCTGCCGATGGAACGGGCCGAGGCGTCCCTGCGTGGCTGGCCGCCGGCGCCGTACGAC
ACCAAGCAGGACACCGACGCCAACTACAAACGGCTGCTGGACTACGCCCTGCATCCCGACCGGGTCGCCAACGTGCGCGT
CGGGGTCGCCGGCCACAACCTGTTCGACCTGGCCTTCGCGTGGCTCCTCGCCGGCCGCCGCGGCGCCCGCGGCGGCCTCC
GCTTCGAGATGCTGCTCGGGATGGCGCAGGCGCAGGCGCGGGTCGTCGCGCGTGAGGTGGGCGGCCTGCTCCTCTACACC
CCGGTGGTGCGGCCGGCGGAGTTCGACGTCGCCATCGCCTACCTGGTCCGCCGGCTCGAGGAGGGCGCGAGCCGGGAGAA
CTTCATGTCGGCCATGTTCGACCTCGCCACCAACGAGACGCTGTTCGCCCGTGAGGAGAAGCGGTTCCGCGCCTCGCTGG
CCGACGTCGACGACACCGTCCCGTCCCCGCGCCGCACCCAGAACCGCCTGCGCGCCACGCCTCCCATCGGCGCAGCGGGG
CCGGCCGGGCCTGATGGCACAGGAGGCTTCCGGAACGCTCCGGACACCGACCCCTCCCTGGCGGCCAACCGGACGTGGGC
GCGGCGCGTCCTGGCCCGGGCGCCGGCGTCCACGCTGGGCGTCGACCTCGTCGCGGTTACCACGATCCGCTCGGCGGACG
AGCTGGACGCGGTGCTGGCACGCGCGGTCGCCGCTGGCCCGGGTTGGGCGGCGCTGGGTGGGGCGGGCCGCGCGGCCGTT
CTACGCCGGGCCGCCGAGGTGCTCGAACAGCGGCGCGGCGAGCTGGTCGAGGTCATGGCCACCGAGACCGCGAAGACCTT
CGACCAGGCCGATCCGGAGGTCTCGGAGGCCGTCGACTTCGCCCGCTACTACGCCGAGCGGGGTGCCGGGCTCGACGACG
TCGACGGGGCGCTGCTCGCGCCGGTGCGCCTCACCGTGGTCACGCCGCCGTGGAACTTCCCGGTCGCGATCCCCGCCGGG
TCCACCCTCGCCGCCCTCGCCGCCGGCTCGCCGGTGGTGATCAAGCCGGCCGGTCAGGCCCGTCGCTGCGGCGCCGTCCT
GGTAAGGGCGCTGTGGGACGCCGGCATCCCCCGCGAGGTCCTCCAGCTCGTCAACGTGGACGAGGGCGACCTCGGCCGGG
CGCTGGTCGGTGACCCTCGCGTCGATCGGGTCATCCTCACCGGCGCGTTCGAGACGGCGGAGCTGTTCCGGTCGTTCCGC
CGCGACCTGCCGCTGCTCGCGGAGACGAGCGGCAAGAACGCGATCGTGGTGACGCCGAGCGCCGACCCCGACCTGGCCGT
GCGCGACGTCGTTGCCTCCGCGTTCGGCCACGCCGGCCAGAAGTGCTCGGCGGCGTCGCTGCTCATCCTCGTCGGCTCTG
CGGCGGCGTCCCGCCGGCTGCGCGACCAGCTCGTCGACGCGGTCCGCTCGCTGGTCGTGGGGGAGTCGGCCGAGCCGCGG
ACCCAGCTCGGGCCGCTCATCGAACCGGCTTCGGGCAAGCTGCTGCGCGCGCTGACCGAGCTCGGCCCGGGCGAGCGCTG
GCTCGTCGAGCCGCGGCGCCTCGACGAACAGGGCCGGCTGTGGTCGCCCGGAGTGCGTGCGGGGGTGTCCCGCGGGTCGG
AGTTCCACCGGACGGAGTACTTCGGCCCGGTCCTGGGGATCATGCCGGCGGCCGATCTCGCTGAGGCCGTGGAGATCCAG
AACGAGGTCGACTTCGGCCTCACCGCGGGCCTGCACTCGCTCGACGCGGCGGAGCTCGACTACTGGCTGCGCCACGTCCA
GGCGGGCAACCTCTACGTGAACCGCGGCATCACCGGCGCGATCGTGGGCCGCCAGCCGTTCGGCGGCTGGAAGCGCTCGG
CGGTGGGCCCGGGAACCAAGGCGGGCGGCCCGACCTACCTCTACGCCCTCGCTGACTGGACCAGCAGACCCAGCTCCGCG
ACGGCCGAGCTCGGACCGACCGCCCGCCGCCTGCTCGCCGTCGTCGCTGAAAGTGACTGTGTAGGAGAGTTCGGCGACGG
TGCCTCCGTTGGTGGCGCCTCCGCTAGTGATGCCTCCGCCGGCGGCGCGTCCGCTGGCGGTGCCGCGCCTGGCGGAGGCG
CCGGTGGTGGGGTCGGCGCGGTCGCGGATCTCGCTGGGCTGGAACGGGCGCTGCGCAGCGACGCGGCCGCCTGGGCCGGC
GGGTACGGCGCCGCCCGCGAGCTCGCCGGGCTGTCCGCCGAGCGCAACATGCTGCGCTACCAGCCCGTTCCGGTCGAGAT
CCGCTTCGCGGGCGGCGGGATCCACCAGCTCGTCCGCGTGGTCGCGGCCGGGCTGCTGGCCGGCTCGCCGTTGCGGGTGA
GCTCCGCGGTCGAGCTCCCGCGGTGGCTACGCGCGGAGCTCGCCGGGCTGGCGGTCGGTAACAGCTGCCAGTCCGACGAC
GAGTGGCTCGCTGACCTGGCCCGACGCCCGGCGAGCCGGGCCGGGCTGCGGGTTCGGCTGATCGGCGGGGACGCCGGCGC
GCTGACGGCCGCGGTCGGTGACCGCCTGGAGATCGCCGTCCACGCGCGGCCGGTGACCGAGTCCGGGCGGCTGGAGTTGC
TGCCGTTCCTGCGCGAGCAGGCGGTCAGCATCACCGCCCACCGCTTCGGTACCCCGGACGGCCTCTCCGACGGCCTCCTC
TGA

Upstream 100 bases:

>100_bases
GCGCCGCGGGTACGACCGGTGTGTACCCCGCCGGTGGGGCCGTGTTGTCGGTGCTCGCGGCCACACTGTGAGAGACAGCC
ACACCGACCCGAGGACGGCG

Downstream 100 bases:

>100_bases
CAACCCGCGCCAACGCCGTGCGCTGAGAGTGGGGGCTCTGACCTGCCGGTGTGTCGCGTCGGCCGATCCGGCCAATGCGC
CTCTTTCGACCATTTCCTAG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1200; Mature: 1199

Protein sequence:

>1200_residues
MTAAVSSSPHDLSDLGDEAVALVRRWVAEAASEPVDPAAARLAAVLREPGGLAFTVRFVDGVIRPEDPRVAARNLARLAP
SVPAFLPWYLRGAVRAGGVAGPVVPWVVVPAARRVLRRMVGHLVVDATDRGLGRAIERLRRPGVQLNMNLLGEAVLGERE
AARRLAGTTALLARDDVDHVSIKVSASVAPHAAWAFEETVAHVVETLTPLFEQAMAARPAESRPATFVTLDMEEYRDLDL
TIEVFTTLLDRPALRRLAAGIVLQAYLPDALGALTRLQEWSASRRAAGGAPVTVRLVKGANLPMERAEASLRGWPPAPYD
TKQDTDANYKRLLDYALHPDRVANVRVGVAGHNLFDLAFAWLLAGRRGARGGLRFEMLLGMAQAQARVVAREVGGLLLYT
PVVRPAEFDVAIAYLVRRLEEGASRENFMSAMFDLATNETLFAREEKRFRASLADVDDTVPSPRRTQNRLRATPPIGAAG
PAGPDGTGGFRNAPDTDPSLAANRTWARRVLARAPASTLGVDLVAVTTIRSADELDAVLARAVAAGPGWAALGGAGRAAV
LRRAAEVLEQRRGELVEVMATETAKTFDQADPEVSEAVDFARYYAERGAGLDDVDGALLAPVRLTVVTPPWNFPVAIPAG
STLAALAAGSPVVIKPAGQARRCGAVLVRALWDAGIPREVLQLVNVDEGDLGRALVGDPRVDRVILTGAFETAELFRSFR
RDLPLLAETSGKNAIVVTPSADPDLAVRDVVASAFGHAGQKCSAASLLILVGSAAASRRLRDQLVDAVRSLVVGESAEPR
TQLGPLIEPASGKLLRALTELGPGERWLVEPRRLDEQGRLWSPGVRAGVSRGSEFHRTEYFGPVLGIMPAADLAEAVEIQ
NEVDFGLTAGLHSLDAAELDYWLRHVQAGNLYVNRGITGAIVGRQPFGGWKRSAVGPGTKAGGPTYLYALADWTSRPSSA
TAELGPTARRLLAVVAESDCVGEFGDGASVGGASASDASAGGASAGGAAPGGGAGGGVGAVADLAGLERALRSDAAAWAG
GYGAARELAGLSAERNMLRYQPVPVEIRFAGGGIHQLVRVVAAGLLAGSPLRVSSAVELPRWLRAELAGLAVGNSCQSDD
EWLADLARRPASRAGLRVRLIGGDAGALTAAVGDRLEIAVHARPVTESGRLELLPFLREQAVSITAHRFGTPDGLSDGLL

Sequences:

>Translated_1200_residues
MTAAVSSSPHDLSDLGDEAVALVRRWVAEAASEPVDPAAARLAAVLREPGGLAFTVRFVDGVIRPEDPRVAARNLARLAP
SVPAFLPWYLRGAVRAGGVAGPVVPWVVVPAARRVLRRMVGHLVVDATDRGLGRAIERLRRPGVQLNMNLLGEAVLGERE
AARRLAGTTALLARDDVDHVSIKVSASVAPHAAWAFEETVAHVVETLTPLFEQAMAARPAESRPATFVTLDMEEYRDLDL
TIEVFTTLLDRPALRRLAAGIVLQAYLPDALGALTRLQEWSASRRAAGGAPVTVRLVKGANLPMERAEASLRGWPPAPYD
TKQDTDANYKRLLDYALHPDRVANVRVGVAGHNLFDLAFAWLLAGRRGARGGLRFEMLLGMAQAQARVVAREVGGLLLYT
PVVRPAEFDVAIAYLVRRLEEGASRENFMSAMFDLATNETLFAREEKRFRASLADVDDTVPSPRRTQNRLRATPPIGAAG
PAGPDGTGGFRNAPDTDPSLAANRTWARRVLARAPASTLGVDLVAVTTIRSADELDAVLARAVAAGPGWAALGGAGRAAV
LRRAAEVLEQRRGELVEVMATETAKTFDQADPEVSEAVDFARYYAERGAGLDDVDGALLAPVRLTVVTPPWNFPVAIPAG
STLAALAAGSPVVIKPAGQARRCGAVLVRALWDAGIPREVLQLVNVDEGDLGRALVGDPRVDRVILTGAFETAELFRSFR
RDLPLLAETSGKNAIVVTPSADPDLAVRDVVASAFGHAGQKCSAASLLILVGSAAASRRLRDQLVDAVRSLVVGESAEPR
TQLGPLIEPASGKLLRALTELGPGERWLVEPRRLDEQGRLWSPGVRAGVSRGSEFHRTEYFGPVLGIMPAADLAEAVEIQ
NEVDFGLTAGLHSLDAAELDYWLRHVQAGNLYVNRGITGAIVGRQPFGGWKRSAVGPGTKAGGPTYLYALADWTSRPSSA
TAELGPTARRLLAVVAESDCVGEFGDGASVGGASASDASAGGASAGGAAPGGGAGGGVGAVADLAGLERALRSDAAAWAG
GYGAARELAGLSAERNMLRYQPVPVEIRFAGGGIHQLVRVVAAGLLAGSPLRVSSAVELPRWLRAELAGLAVGNSCQSDD
EWLADLARRPASRAGLRVRLIGGDAGALTAAVGDRLEIAVHARPVTESGRLELLPFLREQAVSITAHRFGTPDGLSDGLL
>Mature_1199_residues
TAAVSSSPHDLSDLGDEAVALVRRWVAEAASEPVDPAAARLAAVLREPGGLAFTVRFVDGVIRPEDPRVAARNLARLAPS
VPAFLPWYLRGAVRAGGVAGPVVPWVVVPAARRVLRRMVGHLVVDATDRGLGRAIERLRRPGVQLNMNLLGEAVLGEREA
ARRLAGTTALLARDDVDHVSIKVSASVAPHAAWAFEETVAHVVETLTPLFEQAMAARPAESRPATFVTLDMEEYRDLDLT
IEVFTTLLDRPALRRLAAGIVLQAYLPDALGALTRLQEWSASRRAAGGAPVTVRLVKGANLPMERAEASLRGWPPAPYDT
KQDTDANYKRLLDYALHPDRVANVRVGVAGHNLFDLAFAWLLAGRRGARGGLRFEMLLGMAQAQARVVAREVGGLLLYTP
VVRPAEFDVAIAYLVRRLEEGASRENFMSAMFDLATNETLFAREEKRFRASLADVDDTVPSPRRTQNRLRATPPIGAAGP
AGPDGTGGFRNAPDTDPSLAANRTWARRVLARAPASTLGVDLVAVTTIRSADELDAVLARAVAAGPGWAALGGAGRAAVL
RRAAEVLEQRRGELVEVMATETAKTFDQADPEVSEAVDFARYYAERGAGLDDVDGALLAPVRLTVVTPPWNFPVAIPAGS
TLAALAAGSPVVIKPAGQARRCGAVLVRALWDAGIPREVLQLVNVDEGDLGRALVGDPRVDRVILTGAFETAELFRSFRR
DLPLLAETSGKNAIVVTPSADPDLAVRDVVASAFGHAGQKCSAASLLILVGSAAASRRLRDQLVDAVRSLVVGESAEPRT
QLGPLIEPASGKLLRALTELGPGERWLVEPRRLDEQGRLWSPGVRAGVSRGSEFHRTEYFGPVLGIMPAADLAEAVEIQN
EVDFGLTAGLHSLDAAELDYWLRHVQAGNLYVNRGITGAIVGRQPFGGWKRSAVGPGTKAGGPTYLYALADWTSRPSSAT
AELGPTARRLLAVVAESDCVGEFGDGASVGGASASDASAGGASAGGAAPGGGAGGGVGAVADLAGLERALRSDAAAWAGG
YGAARELAGLSAERNMLRYQPVPVEIRFAGGGIHQLVRVVAAGLLAGSPLRVSSAVELPRWLRAELAGLAVGNSCQSDDE
WLADLARRPASRAGLRVRLIGGDAGALTAAVGDRLEIAVHARPVTESGRLELLPFLREQAVSITAHRFGTPDGLSDGLL

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=439, Percent_Identity=26.879271070615, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI25777730, Length=406, Percent_Identity=26.8472906403941, Blast_Score=127, Evalue=8e-29,
Organism=Homo sapiens, GI12007648, Length=427, Percent_Identity=27.6346604215457, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI11095441, Length=399, Percent_Identity=25.062656641604, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI25777724, Length=431, Percent_Identity=27.8422273781903, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI4507229, Length=425, Percent_Identity=26.5882352941176, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI25777728, Length=395, Percent_Identity=27.8481012658228, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI25777736, Length=453, Percent_Identity=29.3598233995585, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI25777734, Length=453, Percent_Identity=29.3598233995585, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI238859541, Length=453, Percent_Identity=29.3598233995585, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI25777732, Length=485, Percent_Identity=25.5670103092783, Blast_Score=115, Evalue=4e-25,
Organism=Homo sapiens, GI25777721, Length=438, Percent_Identity=25.7990867579909, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI115387104, Length=436, Percent_Identity=24.3119266055046, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI21361176, Length=411, Percent_Identity=26.2773722627737, Blast_Score=111, Evalue=4e-24,
Organism=Homo sapiens, GI21614513, Length=412, Percent_Identity=25.7281553398058, Blast_Score=110, Evalue=6e-24,
Organism=Homo sapiens, GI25777726, Length=428, Percent_Identity=27.3364485981308, Blast_Score=108, Evalue=4e-23,
Organism=Homo sapiens, GI238814322, Length=412, Percent_Identity=22.5728155339806, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI310128093, Length=462, Percent_Identity=24.8917748917749, Blast_Score=99, Evalue=4e-20,
Organism=Homo sapiens, GI188035924, Length=431, Percent_Identity=25.2900232018561, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI310128103, Length=462, Percent_Identity=24.8917748917749, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI25952152, Length=422, Percent_Identity=24.8815165876777, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI73695881, Length=330, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI73695879, Length=330, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI4502043, Length=339, Percent_Identity=25.9587020648968, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI238814371, Length=339, Percent_Identity=25.9587020648968, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI71773324, Length=339, Percent_Identity=25.9587020648968, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI310128091, Length=383, Percent_Identity=26.1096605744125, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI310128089, Length=321, Percent_Identity=26.1682242990654, Blast_Score=81, Evalue=7e-15,
Organism=Homo sapiens, GI301500698, Length=258, Percent_Identity=29.0697674418605, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI4557303, Length=323, Percent_Identity=22.2910216718266, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI73466520, Length=323, Percent_Identity=22.2910216718266, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI206597441, Length=321, Percent_Identity=22.4299065420561, Blast_Score=74, Evalue=8e-13,
Organism=Homo sapiens, GI206597439, Length=321, Percent_Identity=22.4299065420561, Blast_Score=74, Evalue=8e-13,
Organism=Homo sapiens, GI22907049, Length=321, Percent_Identity=22.4299065420561, Blast_Score=74, Evalue=8e-13,
Organism=Homo sapiens, GI310128097, Length=246, Percent_Identity=27.6422764227642, Blast_Score=69, Evalue=3e-11,
Organism=Escherichia coli, GI1787250, Length=787, Percent_Identity=32.0203303684879, Blast_Score=255, Evalue=1e-68,
Organism=Escherichia coli, GI1789015, Length=431, Percent_Identity=29.6983758700696, Blast_Score=156, Evalue=7e-39,
Organism=Escherichia coli, GI1788042, Length=415, Percent_Identity=32.289156626506, Blast_Score=137, Evalue=6e-33,
Organism=Escherichia coli, GI87081926, Length=418, Percent_Identity=26.3157894736842, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1787684, Length=414, Percent_Identity=27.2946859903382, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87081896, Length=419, Percent_Identity=28.4009546539379, Blast_Score=119, Evalue=9e-28,
Organism=Escherichia coli, GI87082295, Length=436, Percent_Identity=26.8348623853211, Blast_Score=113, Evalue=9e-26,
Organism=Escherichia coli, GI1787558, Length=415, Percent_Identity=26.7469879518072, Blast_Score=104, Evalue=4e-23,
Organism=Escherichia coli, GI1786504, Length=427, Percent_Identity=24.5901639344262, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1787715, Length=422, Percent_Identity=26.303317535545, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25143876, Length=425, Percent_Identity=27.0588235294118, Blast_Score=132, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI25143874, Length=425, Percent_Identity=27.0588235294118, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=465, Percent_Identity=25.1612903225806, Blast_Score=127, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI115534176, Length=445, Percent_Identity=25.8426966292135, Blast_Score=117, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17562198, Length=417, Percent_Identity=25.4196642685851, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71986308, Length=414, Percent_Identity=25.1207729468599, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25144435, Length=412, Percent_Identity=25, Blast_Score=103, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI133930964, Length=412, Percent_Identity=23.7864077669903, Blast_Score=102, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17534447, Length=474, Percent_Identity=25.5274261603376, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32564736, Length=401, Percent_Identity=25.1870324189526, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI115532534, Length=335, Percent_Identity=27.4626865671642, Blast_Score=97, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17551164, Length=428, Percent_Identity=24.0654205607477, Blast_Score=88, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71995606, Length=452, Percent_Identity=23.6725663716814, Blast_Score=88, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564084, Length=425, Percent_Identity=24, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32566756, Length=376, Percent_Identity=24.2021276595745, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25146391, Length=376, Percent_Identity=24.2021276595745, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25146394, Length=376, Percent_Identity=24.2021276595745, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71995613, Length=409, Percent_Identity=23.2273838630807, Blast_Score=76, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321826, Length=441, Percent_Identity=28.3446712018141, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319478, Length=415, Percent_Identity=26.2650602409639, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6323821, Length=444, Percent_Identity=23.6486486486486, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323822, Length=456, Percent_Identity=23.4649122807018, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6324950, Length=428, Percent_Identity=23.8317757009346, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325196, Length=407, Percent_Identity=25.0614250614251, Blast_Score=104, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6320917, Length=430, Percent_Identity=24.1860465116279, Blast_Score=104, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6321828, Length=350, Percent_Identity=24.5714285714286, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362580, Length=453, Percent_Identity=27.3730684326711, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI62472918, Length=453, Percent_Identity=27.3730684326711, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI62472926, Length=453, Percent_Identity=27.3730684326711, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI62472936, Length=453, Percent_Identity=27.3730684326711, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI21356737, Length=453, Percent_Identity=27.3730684326711, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI20129399, Length=495, Percent_Identity=24.6464646464646, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571802, Length=450, Percent_Identity=26.4444444444444, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571800, Length=450, Percent_Identity=26.4444444444444, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571798, Length=450, Percent_Identity=26.4444444444444, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571796, Length=450, Percent_Identity=26.4444444444444, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571794, Length=450, Percent_Identity=26.4444444444444, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571806, Length=450, Percent_Identity=26.4444444444444, Blast_Score=115, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24668425, Length=462, Percent_Identity=25.1082251082251, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24668417, Length=462, Percent_Identity=25.1082251082251, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24668413, Length=462, Percent_Identity=25.1082251082251, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24650465, Length=470, Percent_Identity=23.8297872340426, Blast_Score=114, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24666674, Length=439, Percent_Identity=23.4624145785877, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585660, Length=436, Percent_Identity=22.2477064220184, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24638876, Length=399, Percent_Identity=23.8095238095238, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24638878, Length=399, Percent_Identity=23.8095238095238, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28574525, Length=457, Percent_Identity=24.2888402625821, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360299, Length=378, Percent_Identity=21.957671957672, Blast_Score=75, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281360297, Length=378, Percent_Identity=21.957671957672, Blast_Score=75, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281360295, Length=378, Percent_Identity=21.957671957672, Blast_Score=75, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24586250, Length=378, Percent_Identity=21.957671957672, Blast_Score=75, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281360301, Length=375, Percent_Identity=22.4, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 126425; Mature: 126294

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAVSSSPHDLSDLGDEAVALVRRWVAEAASEPVDPAAARLAAVLREPGGLAFTVRFVD
CCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECC
GVIRPEDPRVAARNLARLAPSVPAFLPWYLRGAVRAGGVAGPVVPWVVVPAARRVLRRMV
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
GHLVVDATDRGLGRAIERLRRPGVQLNMNLLGEAVLGEREAARRLAGTTALLARDDVDHV
HHHEECCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCHHHHHHHHHCCHHEEECCCCCEE
SIKVSASVAPHAAWAFEETVAHVVETLTPLFEQAMAARPAESRPATFVTLDMEEYRDLDL
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCCH
TIEVFTTLLDRPALRRLAAGIVLQAYLPDALGALTRLQEWSASRRAAGGAPVTVRLVKGA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
NLPMERAEASLRGWPPAPYDTKQDTDANYKRLLDYALHPDRVANVRVGVAGHNLFDLAFA
CCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHH
WLLAGRRGARGGLRFEMLLGMAQAQARVVAREVGGLLLYTPVVRPAEFDVAIAYLVRRLE
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHH
EGASRENFMSAMFDLATNETLFAREEKRFRASLADVDDTVPSPRRTQNRLRATPPIGAAG
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCC
PAGPDGTGGFRNAPDTDPSLAANRTWARRVLARAPASTLGVDLVAVTTIRSADELDAVLA
CCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHCCCHHHCCHHHHHHHHCCHHHHHHHHH
RAVAAGPGWAALGGAGRAAVLRRAAEVLEQRRGELVEVMATETAKTFDQADPEVSEAVDF
HHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHCCCCHHHHHHHH
ARYYAERGAGLDDVDGALLAPVRLTVVTPPWNFPVAIPAGSTLAALAAGSPVVIKPAGQA
HHHHHHHCCCCCCCCCCEECCEEEEEEECCCCCCEEECCCCHHHHHHCCCCEEEECCCCH
RRCGAVLVRALWDAGIPREVLQLVNVDEGDLGRALVGDPRVDRVILTGAFETAELFRSFR
HHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHH
RDLPLLAETSGKNAIVVTPSADPDLAVRDVVASAFGHAGQKCSAASLLILVGSAAASRRL
HCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHEEEEEECCHHHHHHH
RDQLVDAVRSLVVGESAEPRTQLGPLIEPASGKLLRALTELGPGERWLVEPRRLDEQGRL
HHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECHHHCCCCCCC
WSPGVRAGVSRGSEFHRTEYFGPVLGIMPAADLAEAVEIQNEVDFGLTAGLHSLDAAELD
CCCHHHHHHHCCCHHHHHHHHCHHHHHCCHHHHHHHHHHHHHCCCCHHHCCHHCCHHHHH
YWLRHVQAGNLYVNRGITGAIVGRQPFGGWKRSAVGPGTKAGGPTYLYALADWTSRPSSA
HHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCC
TAELGPTARRLLAVVAESDCVGEFGDGASVGGASASDASAGGASAGGAAPGGGAGGGVGA
CHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VADLAGLERALRSDAAAWAGGYGAARELAGLSAERNMLRYQPVPVEIRFAGGGIHQLVRV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHCCHHEECCCCEEEEECCCCHHHHHHH
VAAGLLAGSPLRVSSAVELPRWLRAELAGLAVGNSCQSDDEWLADLARRPASRAGLRVRL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHCCCEEEE
IGGDAGALTAAVGDRLEIAVHARPVTESGRLELLPFLREQAVSITAHRFGTPDGLSDGLL
ECCCCCHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TAAVSSSPHDLSDLGDEAVALVRRWVAEAASEPVDPAAARLAAVLREPGGLAFTVRFVD
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECC
GVIRPEDPRVAARNLARLAPSVPAFLPWYLRGAVRAGGVAGPVVPWVVVPAARRVLRRMV
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
GHLVVDATDRGLGRAIERLRRPGVQLNMNLLGEAVLGEREAARRLAGTTALLARDDVDHV
HHHEECCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCHHHHHHHHHCCHHEEECCCCCEE
SIKVSASVAPHAAWAFEETVAHVVETLTPLFEQAMAARPAESRPATFVTLDMEEYRDLDL
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCCH
TIEVFTTLLDRPALRRLAAGIVLQAYLPDALGALTRLQEWSASRRAAGGAPVTVRLVKGA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
NLPMERAEASLRGWPPAPYDTKQDTDANYKRLLDYALHPDRVANVRVGVAGHNLFDLAFA
CCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHH
WLLAGRRGARGGLRFEMLLGMAQAQARVVAREVGGLLLYTPVVRPAEFDVAIAYLVRRLE
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHH
EGASRENFMSAMFDLATNETLFAREEKRFRASLADVDDTVPSPRRTQNRLRATPPIGAAG
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCC
PAGPDGTGGFRNAPDTDPSLAANRTWARRVLARAPASTLGVDLVAVTTIRSADELDAVLA
CCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHCCCHHHCCHHHHHHHHCCHHHHHHHHH
RAVAAGPGWAALGGAGRAAVLRRAAEVLEQRRGELVEVMATETAKTFDQADPEVSEAVDF
HHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHCCCCHHHHHHHH
ARYYAERGAGLDDVDGALLAPVRLTVVTPPWNFPVAIPAGSTLAALAAGSPVVIKPAGQA
HHHHHHHCCCCCCCCCCEECCEEEEEEECCCCCCEEECCCCHHHHHHCCCCEEEECCCCH
RRCGAVLVRALWDAGIPREVLQLVNVDEGDLGRALVGDPRVDRVILTGAFETAELFRSFR
HHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHH
RDLPLLAETSGKNAIVVTPSADPDLAVRDVVASAFGHAGQKCSAASLLILVGSAAASRRL
HCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHEEEEEECCHHHHHHH
RDQLVDAVRSLVVGESAEPRTQLGPLIEPASGKLLRALTELGPGERWLVEPRRLDEQGRL
HHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECHHHCCCCCCC
WSPGVRAGVSRGSEFHRTEYFGPVLGIMPAADLAEAVEIQNEVDFGLTAGLHSLDAAELD
CCCHHHHHHHCCCHHHHHHHHCHHHHHCCHHHHHHHHHHHHHCCCCHHHCCHHCCHHHHH
YWLRHVQAGNLYVNRGITGAIVGRQPFGGWKRSAVGPGTKAGGPTYLYALADWTSRPSSA
HHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCC
TAELGPTARRLLAVVAESDCVGEFGDGASVGGASASDASAGGASAGGAAPGGGAGGGVGA
CHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VADLAGLERALRSDAAAWAGGYGAARELAGLSAERNMLRYQPVPVEIRFAGGGIHQLVRV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHCCHHEECCCCEEEEECCCCHHHHHHH
VAAGLLAGSPLRVSSAVELPRWLRAELAGLAVGNSCQSDDEWLADLARRPASRAGLRVRL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHCCCEEEE
IGGDAGALTAAVGDRLEIAVHARPVTESGRLELLPFLREQAVSITAHRFGTPDGLSDGLL
ECCCCCHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]