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The map label for this gene is yusP [H]

Identifier: 158315908

GI number: 158315908

Start: 4905158

End: 4906624

Strand: Reverse

Name: yusP [H]

Synonym: Franean1_4123

Alternate gene names: 158315908

Gene position: 4906624-4905158 (Counterclockwise)

Preceding gene: 158315910

Following gene: 158315907

Centisome position: 54.63

GC content: 69.87

Gene sequence:

>1467_bases
ATGATCCAACCTGCCCGCAGAGCCCACCACCAGGTCACGTTTGCCGTACTGGCGCTCGCCGTGGCCACCTACGCCCTGCT
GCAGTCACTGGTCACCCCCGTGCTACCCACGATCATGGAAAGCCTGCACACCAACCAGACCACGGTCACCTGGGTGCTGA
CCGCCTACCTCCTCTCCGCCTCGATCTTCACCCCGATCATGGGCCGCATCGGCGACGCCGTCGGCAAGAAGAAAATGCTG
CTGGTCGCCCTCGGCGCACTCGCCGCGGGCTCCGCCCTGGCCGCGATCGCCACCGGCATCACCCTGATGATCATCGCCCG
CGTCATCCAGGGTGTGGGCGGCGGCATCCTCCCGCTCGCCTTCGGCATCATCCGCGACGAGTTCCCCCTGCCGAAGGTCT
CCAGCGCCATCGGCGTCCTGGCCGCGCTGACCGCGGTCGGCGCCGGCCTCGGCCTCGTCCTGGCCGGCCCGATCGTCGAC
CTGCTCGACTACCACTGGCTGTTCTGGGTTCCCCTGATCATGGTGCTGCTGGCCGCCGCGGCCGCCGTCGTGTTCATCCC
GGAATCCGCCATCCGCACCCCCTCCAGGATCAGCATCACCCCGGCACTGCTGCTCTCCGCCTGGCTGGTCTGCCTGCTGC
TCGGCCTCTCCGAAGGCCCCGACTGGGGCTGGACGTCCGGCAAGGTGCTCGGCCTGCTCGCCGGCGCCGTCATCATCGGC
GGAGCGTGGGTCGTCGTCGAGACCCGCTCCACCGCCCCACTGATCGACATGACCATGATGCGCCTGCCGGCCGTCTGGAC
CACCAACCTCGTCGCCCTGCTCATCGGCGTCGGCATGTACGCCCTCATGGCGTTCCTGCCGCAGTTCGTACAGACCCCGA
CCTCCGCCGGATACGGCTTCGGCGCCACCATCACCGAATCCGGGCTGATCCTGCTGCCGCTGAGCATCACGATGTTCGCC
GTCGGGATCGCTTCCGGCCCGCTGGCCGCCCGCTACGGATCCAAGGCCGTCGTCGTCACCGGCTCCGCGGTCACAATCAT
CTCCTTCGTCCTGACCGCCTTCGCCCACCACGACAAGTGGGAGGTCTACATCGCCACCGCGGTGATGGGCATCGGGCTCG
GCCTGGCCTTCTCCGCCATGGCCAGCCTCATCGTCGAGGCCGTCCCGGCCCACCAGACCGGCGTCGCCTCCGGCATGAAC
GCCAACATCCGCACCATCGGCGGCTCGATCGGCGCCGCACTGATGGCCACCATCGTCACCTCCGGCGCCGGAGGTGACGG
CATACCCAAGGAATCCGGCTACACCAACGGCTTCGCCATGCTCGCCGGCGCCACCGTGCTCGCCCTGATCGCCGCCCTCG
CCATCCCGGCCGCCCGCCGGGGCCACCCGGCGACCGCCCAGGACCTGCCACACGCCGAGCTGGGGCTGGTGCCCGGCGGC
ACCCTGCTCGGCGCCGACCCGGAGTAG

Upstream 100 bases:

>100_bases
CCGTCGCCGGAGGAAGGCCCGGGCCTCGATGGGAACGGAGGATCGACTCCTGTTACGCTCCTTGCGGAGCGGAGGCTCCG
TTCCGTACCCTGGAGGGTCC

Downstream 100 bases:

>100_bases
ACCGCACCGGCCAGGGCATACCAGCTAGGGCCCTACCAGCCGGGACAATCAGGCCAGTCACCCCGTCAGGCCGACCACGG
TCCGTCGGCGCCCACGGCTA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MIQPARRAHHQVTFAVLALAVATYALLQSLVTPVLPTIMESLHTNQTTVTWVLTAYLLSASIFTPIMGRIGDAVGKKKML
LVALGALAAGSALAAIATGITLMIIARVIQGVGGGILPLAFGIIRDEFPLPKVSSAIGVLAALTAVGAGLGLVLAGPIVD
LLDYHWLFWVPLIMVLLAAAAAVVFIPESAIRTPSRISITPALLLSAWLVCLLLGLSEGPDWGWTSGKVLGLLAGAVIIG
GAWVVVETRSTAPLIDMTMMRLPAVWTTNLVALLIGVGMYALMAFLPQFVQTPTSAGYGFGATITESGLILLPLSITMFA
VGIASGPLAARYGSKAVVVTGSAVTIISFVLTAFAHHDKWEVYIATAVMGIGLGLAFSAMASLIVEAVPAHQTGVASGMN
ANIRTIGGSIGAALMATIVTSGAGGDGIPKESGYTNGFAMLAGATVLALIAALAIPAARRGHPATAQDLPHAELGLVPGG
TLLGADPE

Sequences:

>Translated_488_residues
MIQPARRAHHQVTFAVLALAVATYALLQSLVTPVLPTIMESLHTNQTTVTWVLTAYLLSASIFTPIMGRIGDAVGKKKML
LVALGALAAGSALAAIATGITLMIIARVIQGVGGGILPLAFGIIRDEFPLPKVSSAIGVLAALTAVGAGLGLVLAGPIVD
LLDYHWLFWVPLIMVLLAAAAAVVFIPESAIRTPSRISITPALLLSAWLVCLLLGLSEGPDWGWTSGKVLGLLAGAVIIG
GAWVVVETRSTAPLIDMTMMRLPAVWTTNLVALLIGVGMYALMAFLPQFVQTPTSAGYGFGATITESGLILLPLSITMFA
VGIASGPLAARYGSKAVVVTGSAVTIISFVLTAFAHHDKWEVYIATAVMGIGLGLAFSAMASLIVEAVPAHQTGVASGMN
ANIRTIGGSIGAALMATIVTSGAGGDGIPKESGYTNGFAMLAGATVLALIAALAIPAARRGHPATAQDLPHAELGLVPGG
TLLGADPE
>Mature_488_residues
MIQPARRAHHQVTFAVLALAVATYALLQSLVTPVLPTIMESLHTNQTTVTWVLTAYLLSASIFTPIMGRIGDAVGKKKML
LVALGALAAGSALAAIATGITLMIIARVIQGVGGGILPLAFGIIRDEFPLPKVSSAIGVLAALTAVGAGLGLVLAGPIVD
LLDYHWLFWVPLIMVLLAAAAAVVFIPESAIRTPSRISITPALLLSAWLVCLLLGLSEGPDWGWTSGKVLGLLAGAVIIG
GAWVVVETRSTAPLIDMTMMRLPAVWTTNLVALLIGVGMYALMAFLPQFVQTPTSAGYGFGATITESGLILLPLSITMFA
VGIASGPLAARYGSKAVVVTGSAVTIISFVLTAFAHHDKWEVYIATAVMGIGLGLAFSAMASLIVEAVPAHQTGVASGMN
ANIRTIGGSIGAALMATIVTSGAGGDGIPKESGYTNGFAMLAGATVLALIAALAIPAARRGHPATAQDLPHAELGLVPGG
TLLGADPE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=419, Percent_Identity=22.673031026253, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081983, Length=398, Percent_Identity=25.6281407035176, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789042, Length=436, Percent_Identity=23.6238532110092, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790195, Length=422, Percent_Identity=21.8009478672986, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788392, Length=452, Percent_Identity=23.0088495575221, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322958, Length=338, Percent_Identity=27.5147928994083, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324954, Length=425, Percent_Identity=22.5882352941176, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49792; Mature: 49792

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQPARRAHHQVTFAVLALAVATYALLQSLVTPVLPTIMESLHTNQTTVTWVLTAYLLSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SIFTPIMGRIGDAVGKKKMLLVALGALAAGSALAAIATGITLMIIARVIQGVGGGILPLA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FGIIRDEFPLPKVSSAIGVLAALTAVGAGLGLVLAGPIVDLLDYHWLFWVPLIMVLLAAA
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVVFIPESAIRTPSRISITPALLLSAWLVCLLLGLSEGPDWGWTSGKVLGLLAGAVIIG
HHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC
GAWVVVETRSTAPLIDMTMMRLPAVWTTNLVALLIGVGMYALMAFLPQFVQTPTSAGYGF
CEEEEEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GATITESGLILLPLSITMFAVGIASGPLAARYGSKAVVVTGSAVTIISFVLTAFAHHDKW
CCEECCCCEEEEHHHHHHHHHHHCCCCHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCH
EVYIATAVMGIGLGLAFSAMASLIVEAVPAHQTGVASGMNANIRTIGGSIGAALMATIVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEECCHHHHHHHHHHHHH
SGAGGDGIPKESGYTNGFAMLAGATVLALIAALAIPAARRGHPATAQDLPHAELGLVPGG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHCCCCCCCCCCCCC
TLLGADPE
CCCCCCCC
>Mature Secondary Structure
MIQPARRAHHQVTFAVLALAVATYALLQSLVTPVLPTIMESLHTNQTTVTWVLTAYLLSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SIFTPIMGRIGDAVGKKKMLLVALGALAAGSALAAIATGITLMIIARVIQGVGGGILPLA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FGIIRDEFPLPKVSSAIGVLAALTAVGAGLGLVLAGPIVDLLDYHWLFWVPLIMVLLAAA
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVVFIPESAIRTPSRISITPALLLSAWLVCLLLGLSEGPDWGWTSGKVLGLLAGAVIIG
HHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC
GAWVVVETRSTAPLIDMTMMRLPAVWTTNLVALLIGVGMYALMAFLPQFVQTPTSAGYGF
CEEEEEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GATITESGLILLPLSITMFAVGIASGPLAARYGSKAVVVTGSAVTIISFVLTAFAHHDKW
CCEECCCCEEEEHHHHHHHHHHHCCCCHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCH
EVYIATAVMGIGLGLAFSAMASLIVEAVPAHQTGVASGMNANIRTIGGSIGAALMATIVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEECCHHHHHHHHHHHHH
SGAGGDGIPKESGYTNGFAMLAGATVLALIAALAIPAARRGHPATAQDLPHAELGLVPGG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHCCCCCCCCCCCCC
TLLGADPE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]