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The map label for this gene is pksE [H]

Identifier: 158315740

GI number: 158315740

Start: 4725004

End: 4726656

Strand: Reverse

Name: pksE [H]

Synonym: Franean1_3952

Alternate gene names: 158315740

Gene position: 4726656-4725004 (Counterclockwise)

Preceding gene: 158315741

Following gene: 158315739

Centisome position: 52.62

GC content: 77.07

Gene sequence:

>1653_bases
GTGGTGACCCCGGTCGCGCCCGCCCCCCGCCCCGCGGCGGCTCAGCCGGCCACGGCCCACCCCGGCGCGGCCGGGGCACT
CGCCCGGCGGCCGGCCGACATCCACCGGGTGCTCGCCGATCTGGAGCGGCCCTGCTACGTCGTGCAGGACGCGGCGGGGC
TCGGCGTCACCGGCGACGAGCGGGTCGCCGCGGCGGCCGGGCGGGTCCTGGCCGCGGTCGGCCCGCTGCCGCCGGAGCGC
CTCGGCGCCCCGGCGTTCCGCCGCGACCACCAGGTCGCCCAGGCGTACATGGCCGGGTCGATGGCTAACGGCATCGCGTC
GGCCGACCTGGTCGTCGCGCTGGCCCGGGCGGGCTTCCTGGCCTCGTTCGGCGCGGCCGGCGTCGTCGCCGCCCGGGTCG
ACGACGCGCTGGCCGACATCCGCCGGCGGGCACCGGGCCTGGCGTTCGGCTGCAACCTGATCCACAGCCCGACCGAGGCG
GCGATGGAGCGCGACGTCGTCGACGCCTGCCTGCGCCACCAGGTGCGCTGCGTCGAGGCGTCGGCGTTCCTGGACCTCAC
CCCGCAGGTGGTGCGCTACCGGGTCGCCGGGCTGCGCCGCGGCCCCGACGGCCGGGCCGTCGCCGACAACCGCGTCGTCG
CCAAGGTGTCGCGCACCGAGGTCGCCGAGCTGTTCCTGCGGCCCGCGCCGGCCGCGCTGGTCCGTCCGCTGGTGGAGCAG
GGGCTGGTCAGCGCCGAGCAGGCGGAGCTGGCGGCGACGGTGGCGATGGCCGACGACGTCACCGCCGAGGCCGACTCCGG
CGGGCACACCGACCGCCGGCCGCTGCCCGTCCTGCTGCCCGAGCTGCTCGCGCTGCGCGACAGCCTGCGCGGCGAGTCCG
GAGGGCGCACCGTGCGGATCGGGGCGGCCGGCGGGCTCGGCACCCCGCGCGCCGTCGCCGCCGCGTTCACGCTCGGCGCG
GACTACGTGGTGACCGGCTCGGTCAACCAGGCCTCCGTCGAGGCGGCGCAGTCGCCGGCCACCAAGACGCTGCTGGCCCA
GGCGGGCGTCACCGACTGCGTCCAGGCGCCGTCGGCGGACATGTTCGAGATCGGCGCGGACGTCCAGGTGCTCGGCCGGG
GCACCATGTTCGCGTCGAAGGCGCGCCGGCTCTACGAGCTGTACCGCCGCTTCGACGGGCTCGACGAGATCCCGGCCGAC
GAACGCGCGGGCCTGGAGCAGCGGATCTTCCGCCGCTCGCTGGACGAGGTCTGGGCCGACACCGTCTCCTACTTCAGCAC
CCGCGACCCCGAGCAGATCGAACGCGCCCAGGAGAACCCGAAGCGGCGGATGGCGCTGGTCTTCCGCTGGTATCTCGGGC
TGTCGTCGGGCTGGAGCATCGCCGGTGCCCCGGACCGGGTCGCCGACTACCAGGTCTGGTGCGGCCCGGCGATGGGCGCC
TTCAACACCTGGGTGCGCGCCAGCGCGCTCGAGCCGCTGGCGAACCGGCACGCCGCCGTGATCGCCGCCGAGCTGATGCG
CGGCGCCGCGTTCACCAGCCGGGCCGCCGCGCTGGCCCAGGCCGGCGTCCGGCTGCCGGCGCTCGCCACGACCTACGTGC
CGCGGCCGCACCTGCCGCGGCCAGATTCCGATCCGGGAGAGCAGGCACCATGA

Upstream 100 bases:

>100_bases
GGGTCCGCGTCACCGCCGACGCGAGCCTGTGGAAGCCGACGATGCGCATCTACGAGCTGATCGACGTGGCCGTGGAGCTG
CGTGACGAGGGCGCGCCGTC

Downstream 100 bases:

>100_bases
CAGCATCGGCAACCCGGCAACGGCCCGAGGCGGATCTCGGGACGGCGGAATGGCTCGTCTGCGACGGCTGCCGCCGGATG
ATCTACGGCCGGCGGTTCGC

Product: PfaD family protein

Products: NA

Alternate protein names: Malonyl CoA-acyl carrier protein transacylase; MCT [H]

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MVTPVAPAPRPAAAQPATAHPGAAGALARRPADIHRVLADLERPCYVVQDAAGLGVTGDERVAAAAGRVLAAVGPLPPER
LGAPAFRRDHQVAQAYMAGSMANGIASADLVVALARAGFLASFGAAGVVAARVDDALADIRRRAPGLAFGCNLIHSPTEA
AMERDVVDACLRHQVRCVEASAFLDLTPQVVRYRVAGLRRGPDGRAVADNRVVAKVSRTEVAELFLRPAPAALVRPLVEQ
GLVSAEQAELAATVAMADDVTAEADSGGHTDRRPLPVLLPELLALRDSLRGESGGRTVRIGAAGGLGTPRAVAAAFTLGA
DYVVTGSVNQASVEAAQSPATKTLLAQAGVTDCVQAPSADMFEIGADVQVLGRGTMFASKARRLYELYRRFDGLDEIPAD
ERAGLEQRIFRRSLDEVWADTVSYFSTRDPEQIERAQENPKRRMALVFRWYLGLSSGWSIAGAPDRVADYQVWCGPAMGA
FNTWVRASALEPLANRHAAVIAAELMRGAAFTSRAAALAQAGVRLPALATTYVPRPHLPRPDSDPGEQAP

Sequences:

>Translated_550_residues
MVTPVAPAPRPAAAQPATAHPGAAGALARRPADIHRVLADLERPCYVVQDAAGLGVTGDERVAAAAGRVLAAVGPLPPER
LGAPAFRRDHQVAQAYMAGSMANGIASADLVVALARAGFLASFGAAGVVAARVDDALADIRRRAPGLAFGCNLIHSPTEA
AMERDVVDACLRHQVRCVEASAFLDLTPQVVRYRVAGLRRGPDGRAVADNRVVAKVSRTEVAELFLRPAPAALVRPLVEQ
GLVSAEQAELAATVAMADDVTAEADSGGHTDRRPLPVLLPELLALRDSLRGESGGRTVRIGAAGGLGTPRAVAAAFTLGA
DYVVTGSVNQASVEAAQSPATKTLLAQAGVTDCVQAPSADMFEIGADVQVLGRGTMFASKARRLYELYRRFDGLDEIPAD
ERAGLEQRIFRRSLDEVWADTVSYFSTRDPEQIERAQENPKRRMALVFRWYLGLSSGWSIAGAPDRVADYQVWCGPAMGA
FNTWVRASALEPLANRHAAVIAAELMRGAAFTSRAAALAQAGVRLPALATTYVPRPHLPRPDSDPGEQAP
>Mature_550_residues
MVTPVAPAPRPAAAQPATAHPGAAGALARRPADIHRVLADLERPCYVVQDAAGLGVTGDERVAAAAGRVLAAVGPLPPER
LGAPAFRRDHQVAQAYMAGSMANGIASADLVVALARAGFLASFGAAGVVAARVDDALADIRRRAPGLAFGCNLIHSPTEA
AMERDVVDACLRHQVRCVEASAFLDLTPQVVRYRVAGLRRGPDGRAVADNRVVAKVSRTEVAELFLRPAPAALVRPLVEQ
GLVSAEQAELAATVAMADDVTAEADSGGHTDRRPLPVLLPELLALRDSLRGESGGRTVRIGAAGGLGTPRAVAAAFTLGA
DYVVTGSVNQASVEAAQSPATKTLLAQAGVTDCVQAPSADMFEIGADVQVLGRGTMFASKARRLYELYRRFDGLDEIPAD
ERAGLEQRIFRRSLDEVWADTVSYFSTRDPEQIERAQENPKRRMALVFRWYLGLSSGWSIAGAPDRVADYQVWCGPAMGA
FNTWVRASALEPLANRHAAVIAAELMRGAAFTSRAAALAQAGVRLPALATTYVPRPHLPRPDSDPGEQAP

Specific function: Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably has an acyl transferase activity and could also have a flavin mononucleotide-dependent oxidoreductas

COG id: COG2070

COG function: function code R; Dioxygenases related to 2-nitropropane dioxygenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the fabD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004136
- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013785
- InterPro:   IPR004410
- InterPro:   IPR016036
- InterPro:   IPR014179 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF03060 NPD [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 57943; Mature: 57943

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTPVAPAPRPAAAQPATAHPGAAGALARRPADIHRVLADLERPCYVVQDAAGLGVTGDE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCH
RVAAAAGRVLAAVGPLPPERLGAPAFRRDHQVAQAYMAGSMANGIASADLVVALARAGFL
HHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ASFGAAGVVAARVDDALADIRRRAPGLAFGCNLIHSPTEAAMERDVVDACLRHQVRCVEA
HHHCCHHHHHHHHHHHHHHHHHHCCCCEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SAFLDLTPQVVRYRVAGLRRGPDGRAVADNRVVAKVSRTEVAELFLRPAPAALVRPLVEQ
HHHHCCCHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GLVSAEQAELAATVAMADDVTAEADSGGHTDRRPLPVLLPELLALRDSLRGESGGRTVRI
HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
GAAGGLGTPRAVAAAFTLGADYVVTGSVNQASVEAAQSPATKTLLAQAGVTDCVQAPSAD
ECCCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCHHHHHHHHCCCHHHHHCCCCC
MFEIGADVQVLGRGTMFASKARRLYELYRRFDGLDEIPADERAGLEQRIFRRSLDEVWAD
HHHCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHH
TVSYFSTRDPEQIERAQENPKRRMALVFRWYLGLSSGWSIAGAPDRVADYQVWCGPAMGA
HHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCEEEECCCHHH
FNTWVRASALEPLANRHAAVIAAELMRGAAFTSRAAALAQAGVRLPALATTYVPRPHLPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCC
PDSDPGEQAP
CCCCCCCCCC
>Mature Secondary Structure
MVTPVAPAPRPAAAQPATAHPGAAGALARRPADIHRVLADLERPCYVVQDAAGLGVTGDE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCH
RVAAAAGRVLAAVGPLPPERLGAPAFRRDHQVAQAYMAGSMANGIASADLVVALARAGFL
HHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ASFGAAGVVAARVDDALADIRRRAPGLAFGCNLIHSPTEAAMERDVVDACLRHQVRCVEA
HHHCCHHHHHHHHHHHHHHHHHHCCCCEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SAFLDLTPQVVRYRVAGLRRGPDGRAVADNRVVAKVSRTEVAELFLRPAPAALVRPLVEQ
HHHHCCCHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GLVSAEQAELAATVAMADDVTAEADSGGHTDRRPLPVLLPELLALRDSLRGESGGRTVRI
HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
GAAGGLGTPRAVAAAFTLGADYVVTGSVNQASVEAAQSPATKTLLAQAGVTDCVQAPSAD
ECCCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCHHHHHHHHCCCHHHHHCCCCC
MFEIGADVQVLGRGTMFASKARRLYELYRRFDGLDEIPADERAGLEQRIFRRSLDEVWAD
HHHCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHH
TVSYFSTRDPEQIERAQENPKRRMALVFRWYLGLSSGWSIAGAPDRVADYQVWCGPAMGA
HHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCEEEECCCHHH
FNTWVRASALEPLANRHAAVIAAELMRGAAFTSRAAALAQAGVRLPALATTYVPRPHLPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCC
PDSDPGEQAP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]