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The map label for this gene is accD

Identifier: 158315739

GI number: 158315739

Start: 4723163

End: 4725007

Strand: Reverse

Name: accD

Synonym: Franean1_3951

Alternate gene names: 158315739

Gene position: 4725007-4723163 (Counterclockwise)

Preceding gene: 158315740

Following gene: 158315738

Centisome position: 52.61

GC content: 76.1

Gene sequence:

>1845_bases
ATGACAGCATCGGCAACCCGGCAACGGCCCGAGGCGGATCTCGGGACGGCGGAATGGCTCGTCTGCGACGGCTGCCGCCG
GATGATCTACGGCCGGCGGTTCGCCCGCGGCGGGCACGTCTGCCCCGAATGCGGCTGGCACGCCCGGCTGACCGCGACGC
AGCGGATCGCGCTGCTGCTCGACGAGGGCTCCGTCGAGGTGGTCGACACCCCGGTCACCGCGGCCGACCCGCTGCAGTTC
GTCGACACCCGCCCGTACGCCGACCGGTTGCGCTCGGCGCGGACGTCCACGGGCCTGACCGAGGCGGTCGTGGTGGCCCG
CGGACGGATCGAGGGCTGCCCGGTCGTCACCGCGGTGATGGACTTCCGCTTCCTCGGTGGCAGCCTCGGCGCCGCCGTCG
GCGAGGCGATCACCGGGGCGTGCGAGATCGCCCTGCGCGAGCGCACCCCACTGCTGCTGGTGACCGCCTCCGGCGGCGCG
CGGATGCAGGAGGGCGCGCTGTCGCTGATGCAGATGGCGAAGACGGCCCAGGCGATCGGCCAACTCGACGAGGCCGGCAT
CCTCACCGTCTCCCTCATCACGGACCCGACGTTCGGCGGGGTCGCGGCCTCGTTCGCGACGCTGACCGACGTCATCGTCG
CCGAGCCCGGGGCACGGCTCGGCTTCGCCGGGGCGCGGGTGATCGAGCAGACCATCCGGCAGACGCTGCCACCCGGCTTC
CAGACCGCGGAGTTCCTGCTGGAGCATGGCGTCGTCGACCTGATCAGCCCGCGGGGGCAGCTACGCCCGACGCTGGCCCG
CCTGCTCGGCGTCGCCACCCGCCGCCCCGGCACCGCGCCGGTCACGCCCGGCGACGGGCACAGCGCTGGCGACGGGCGCG
GTGCCGGCGACAGCCGCGGCGCAAGCCACGGCGGTGACGGTGTGGTGCGGGATCCGGCGCGGCTGGCGGACCGCCATCCG
TGGGAGGCCGTGCGGCTCGCCCGCAGGCTGGGCCGGCCCAGCACGCTGGACTACATCGGCGCGCTGGTCGAGGACTGGAC
CGAGCTGCACGGCGACCGGGCCGCCACCGACTGCCCGGCGATGGTCGCCGGGCTCGGCCGCCTCGACGGGACGCCCGTCG
TCGTCATCGGCACGCAGAAGGGCCACACCGCCACCGAGCTCGCCGCCCGCTCCTACGGCATGCCCTCGCCCGGCGGCTAC
CGCAAGGCCGCGCGGGTGATGCGGCTGGCCGCCAAGCTGGGCCTGCCGGTGATCACCCTCATCGACACCGCCGGCGCGCA
CCCCGGCCTCGAGGCCGAGCAGAACGGGCAGGCCGTCGCCATCGCCGAGAACCTGCGGCTGATGGCCGGACTGCCCGTGC
CCGTCGTCGCCGTCGTGACCGGCGAGGGCGGCAGCGGCGGGGCACTGGCCCTGGCCGTCGCCAACCGGGTGCTGATGTGC
GCGAACGCGATCTACTCGGTGATCAGTCCCGAGGGCTGCGCCGCCATCCTGTGGAAGGACCCGGCGGCCGGGCCGGACGC
GGCCGCGGCGCTGCGGGTCGACGCCCGCGCGCTGCTGGCCGCCGGCATCGTCGACGGTGTCGTCCCCGAGCCCGACGGCG
GCGCGGACGTCGATCCGCTGGCCGCCACCGACGCGCTGCGGGCCGCTCTCACCGGCGCGCTCGCCGAGCTGGCGCCGCTG
GACCCACCGACGCTGGTGACGGCCCGACGGGCCCGGTTCCGCCGTTTCGGTACCCCGGCCCCGGCGGGCGGGGCCGCCCC
GGCTCCCGTCGTCCCGGCGGCACGTCCACCACTCGGCGCGGGCCGGACCCATGCCGATCTCGACGATGCGAGGCGCGCGT
CATGA

Upstream 100 bases:

>100_bases
CGCTGGCCCAGGCCGGCGTCCGGCTGCCGGCGCTCGCCACGACCTACGTGCCGCGGCCGCACCTGCCGCGGCCAGATTCC
GATCCGGGAGAGCAGGCACC

Downstream 100 bases:

>100_bases
CCACGTCCACGGCCAACGGCCGGTCCACGACGACGGCGAACGGGCACGGTGACATCGGCACGGTGCTGGCGGTGCTGCGC
CAGGAGGCGCTGGAGGTCGG

Product: acetyl-CoA carboxylase, carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunits beta/alpha; Acetyl-CoA carboxylase carboxyltransferase subunits beta/alpha

Number of amino acids: Translated: 614; Mature: 613

Protein sequence:

>614_residues
MTASATRQRPEADLGTAEWLVCDGCRRMIYGRRFARGGHVCPECGWHARLTATQRIALLLDEGSVEVVDTPVTAADPLQF
VDTRPYADRLRSARTSTGLTEAVVVARGRIEGCPVVTAVMDFRFLGGSLGAAVGEAITGACEIALRERTPLLLVTASGGA
RMQEGALSLMQMAKTAQAIGQLDEAGILTVSLITDPTFGGVAASFATLTDVIVAEPGARLGFAGARVIEQTIRQTLPPGF
QTAEFLLEHGVVDLISPRGQLRPTLARLLGVATRRPGTAPVTPGDGHSAGDGRGAGDSRGASHGGDGVVRDPARLADRHP
WEAVRLARRLGRPSTLDYIGALVEDWTELHGDRAATDCPAMVAGLGRLDGTPVVVIGTQKGHTATELAARSYGMPSPGGY
RKAARVMRLAAKLGLPVITLIDTAGAHPGLEAEQNGQAVAIAENLRLMAGLPVPVVAVVTGEGGSGGALALAVANRVLMC
ANAIYSVISPEGCAAILWKDPAAGPDAAAALRVDARALLAAGIVDGVVPEPDGGADVDPLAATDALRAALTGALAELAPL
DPPTLVTARRARFRRFGTPAPAGGAAPAPVVPAARPPLGAGRTHADLDDARRAS

Sequences:

>Translated_614_residues
MTASATRQRPEADLGTAEWLVCDGCRRMIYGRRFARGGHVCPECGWHARLTATQRIALLLDEGSVEVVDTPVTAADPLQF
VDTRPYADRLRSARTSTGLTEAVVVARGRIEGCPVVTAVMDFRFLGGSLGAAVGEAITGACEIALRERTPLLLVTASGGA
RMQEGALSLMQMAKTAQAIGQLDEAGILTVSLITDPTFGGVAASFATLTDVIVAEPGARLGFAGARVIEQTIRQTLPPGF
QTAEFLLEHGVVDLISPRGQLRPTLARLLGVATRRPGTAPVTPGDGHSAGDGRGAGDSRGASHGGDGVVRDPARLADRHP
WEAVRLARRLGRPSTLDYIGALVEDWTELHGDRAATDCPAMVAGLGRLDGTPVVVIGTQKGHTATELAARSYGMPSPGGY
RKAARVMRLAAKLGLPVITLIDTAGAHPGLEAEQNGQAVAIAENLRLMAGLPVPVVAVVTGEGGSGGALALAVANRVLMC
ANAIYSVISPEGCAAILWKDPAAGPDAAAALRVDARALLAAGIVDGVVPEPDGGADVDPLAATDALRAALTGALAELAPL
DPPTLVTARRARFRRFGTPAPAGGAAPAPVVPAARPPLGAGRTHADLDDARRAS
>Mature_613_residues
TASATRQRPEADLGTAEWLVCDGCRRMIYGRRFARGGHVCPECGWHARLTATQRIALLLDEGSVEVVDTPVTAADPLQFV
DTRPYADRLRSARTSTGLTEAVVVARGRIEGCPVVTAVMDFRFLGGSLGAAVGEAITGACEIALRERTPLLLVTASGGAR
MQEGALSLMQMAKTAQAIGQLDEAGILTVSLITDPTFGGVAASFATLTDVIVAEPGARLGFAGARVIEQTIRQTLPPGFQ
TAEFLLEHGVVDLISPRGQLRPTLARLLGVATRRPGTAPVTPGDGHSAGDGRGAGDSRGASHGGDGVVRDPARLADRHPW
EAVRLARRLGRPSTLDYIGALVEDWTELHGDRAATDCPAMVAGLGRLDGTPVVVIGTQKGHTATELAARSYGMPSPGGYR
KAARVMRLAAKLGLPVITLIDTAGAHPGLEAEQNGQAVAIAENLRLMAGLPVPVVAVVTGEGGSGGALALAVANRVLMCA
NAIYSVISPEGCAAILWKDPAAGPDAAAALRVDARALLAAGIVDGVVPEPDGGADVDPLAATDALRAALTGALAELAPLD
PPTLVTARRARFRRFGTPAPAGGAAPAPVVPAARPPLGAGRTHADLDDARRAS

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1788655, Length=268, Percent_Identity=47.3880597014925, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1786382, Length=263, Percent_Identity=48.2889733840304, Blast_Score=241, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCDA_FRASN (A8L4H3)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001508247.1
- GeneID:   5672312
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_3951
- HOGENOM:   HBG668219
- OMA:   GASAIVH
- ProtClustDB:   CLSK911920
- BioCyc:   FSP1855:FRANEAN1_3951-MONOMER
- HAMAP:   MF_00823
- HAMAP:   MF_01395
- InterPro:   IPR001095
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00513
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF03255 ACCA; PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 63113; Mature: 62982

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50989 COA_CT_CTER; PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASATRQRPEADLGTAEWLVCDGCRRMIYGRRFARGGHVCPECGWHARLTATQRIALLL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEE
DEGSVEVVDTPVTAADPLQFVDTRPYADRLRSARTSTGLTEAVVVARGRIEGCPVVTAVM
ECCCEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHH
DFRFLGGSLGAAVGEAITGACEIALRERTPLLLVTASGGARMQEGALSLMQMAKTAQAIG
HHHHHCCHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
QLDEAGILTVSLITDPTFGGVAASFATLTDVIVAEPGARLGFAGARVIEQTIRQTLPPGF
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCH
QTAEFLLEHGVVDLISPRGQLRPTLARLLGVATRRPGTAPVTPGDGHSAGDGRGAGDSRG
HHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
ASHGGDGVVRDPARLADRHPWEAVRLARRLGRPSTLDYIGALVEDWTELHGDRAATDCPA
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHH
MVAGLGRLDGTPVVVIGTQKGHTATELAARSYGMPSPGGYRKAARVMRLAAKLGLPVITL
HHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEE
IDTAGAHPGLEAEQNGQAVAIAENLRLMAGLPVPVVAVVTGEGGSGGALALAVANRVLMC
EECCCCCCCCCCCCCCCEEEEECCCHHEECCCCCEEEEEECCCCCCCEEHHHHHHHHHHH
ANAIYSVISPEGCAAILWKDPAAGPDAAAALRVDARALLAAGIVDGVVPEPDGGADVDPL
HHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
AATDALRAALTGALAELAPLDPPTLVTARRARFRRFGTPAPAGGAAPAPVVPAARPPLGA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GRTHADLDDARRAS
CCCCCCHHHHHCCC
>Mature Secondary Structure 
TASATRQRPEADLGTAEWLVCDGCRRMIYGRRFARGGHVCPECGWHARLTATQRIALLL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEE
DEGSVEVVDTPVTAADPLQFVDTRPYADRLRSARTSTGLTEAVVVARGRIEGCPVVTAVM
ECCCEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHH
DFRFLGGSLGAAVGEAITGACEIALRERTPLLLVTASGGARMQEGALSLMQMAKTAQAIG
HHHHHCCHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
QLDEAGILTVSLITDPTFGGVAASFATLTDVIVAEPGARLGFAGARVIEQTIRQTLPPGF
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCH
QTAEFLLEHGVVDLISPRGQLRPTLARLLGVATRRPGTAPVTPGDGHSAGDGRGAGDSRG
HHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
ASHGGDGVVRDPARLADRHPWEAVRLARRLGRPSTLDYIGALVEDWTELHGDRAATDCPA
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHH
MVAGLGRLDGTPVVVIGTQKGHTATELAARSYGMPSPGGYRKAARVMRLAAKLGLPVITL
HHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEE
IDTAGAHPGLEAEQNGQAVAIAENLRLMAGLPVPVVAVVTGEGGSGGALALAVANRVLMC
EECCCCCCCCCCCCCCCEEEEECCCHHEECCCCCEEEEEECCCCCCCEEHHHHHHHHHHH
ANAIYSVISPEGCAAILWKDPAAGPDAAAALRVDARALLAAGIVDGVVPEPDGGADVDPL
HHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
AATDALRAALTGALAELAPLDPPTLVTARRARFRRFGTPAPAGGAAPAPVVPAARPPLGA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GRTHADLDDARRAS
CCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA