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The map label for this gene is accB [H]

Identifier: 158315738

GI number: 158315738

Start: 4722543

End: 4723166

Strand: Reverse

Name: accB [H]

Synonym: Franean1_3950

Alternate gene names: 158315738

Gene position: 4723166-4722543 (Counterclockwise)

Preceding gene: 158315739

Following gene: 158315737

Centisome position: 52.58

GC content: 74.36

Gene sequence:

>624_bases
ATGACCACGTCCACGGCCAACGGCCGGTCCACGACGACGGCGAACGGGCACGGTGACATCGGCACGGTGCTGGCGGTGCT
GCGCCAGGAGGCGCTGGAGGTCGGCGCGCGCGGCGCGCGGCCGGTCAGCCGGGTGCGGGTGACCGTCGGCGACGTCTCCC
TGGAGGTCGACTGGGCCGGGCCGGGCGGGGCCACCGGCTCCGACGGTCCCGGTCAACACAGCACGCCCCCGCAGGCCAAC
GGCTCCGGCGGTCTCGGCTCAGTCAGCGCCGCGCCCAGCGACACCAACGGTTCCACCGCGTCGGGCGCTGACGCCGGTGT
TGGTGCCGCGGCACCGGCCGGTCCGGCGGACGACGACGCACTCGCGTTCGTCATCCCGGCACACACCGTCGGCGTTTTCT
ACCACGCGCCCGAGCCGGGCGCGGACCCGTTCGTCCGCCCCGGGGACACCGTCGTCGCTGGCCAGCAGGTCGGGATCATC
GAGGCGATGAAGCTGATGATCCCGGTCGAGGCGGAGCGCGGTGGGCGGGTCCGGGAGATCCTGGTCGCCGACACCACCCC
GGTGGAGTACGGCGAACCGCTGCTCACCCTTGACGTCGCCACGTCCACCGGCGGGGCCTCGTGA

Upstream 100 bases:

>100_bases
CGGCGGGCGGGGCCGCCCCGGCTCCCGTCGTCCCGGCGGCACGTCCACCACTCGGCGCGGGCCGGACCCATGCCGATCTC
GACGATGCGAGGCGCGCGTC

Downstream 100 bases:

>100_bases
TCAAGAAGGTCCTGATCGCGAACCGCGGGGAGATCGCGCTGCGGGTCGCGCGCACCTGCCGCGAGCTGGGCATCGCCACC
GTGGCCGCCCACTCGTCGGC

Product: biotin/lipoyl attachment domain-containing protein

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MTTSTANGRSTTTANGHGDIGTVLAVLRQEALEVGARGARPVSRVRVTVGDVSLEVDWAGPGGATGSDGPGQHSTPPQAN
GSGGLGSVSAAPSDTNGSTASGADAGVGAAAPAGPADDDALAFVIPAHTVGVFYHAPEPGADPFVRPGDTVVAGQQVGII
EAMKLMIPVEAERGGRVREILVADTTPVEYGEPLLTLDVATSTGGAS

Sequences:

>Translated_207_residues
MTTSTANGRSTTTANGHGDIGTVLAVLRQEALEVGARGARPVSRVRVTVGDVSLEVDWAGPGGATGSDGPGQHSTPPQAN
GSGGLGSVSAAPSDTNGSTASGADAGVGAAAPAGPADDDALAFVIPAHTVGVFYHAPEPGADPFVRPGDTVVAGQQVGII
EAMKLMIPVEAERGGRVREILVADTTPVEYGEPLLTLDVATSTGGAS
>Mature_206_residues
TTSTANGRSTTTANGHGDIGTVLAVLRQEALEVGARGARPVSRVRVTVGDVSLEVDWAGPGGATGSDGPGQHSTPPQANG
SGGLGSVSAAPSDTNGSTASGADAGVGAAAPAGPADDDALAFVIPAHTVGVFYHAPEPGADPFVRPGDTVVAGQQVGIIE
AMKLMIPVEAERGGRVREILVADTTPVEYGEPLLTLDVATSTGGAS

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789653, Length=97, Percent_Identity=38.1443298969072, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: NA

Molecular weight: Translated: 20345; Mature: 20213

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSTANGRSTTTANGHGDIGTVLAVLRQEALEVGARGARPVSRVRVTVGDVSLEVDWAG
CCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEEECC
PGGATGSDGPGQHSTPPQANGSGGLGSVSAAPSDTNGSTASGADAGVGAAAPAGPADDDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LAFVIPAHTVGVFYHAPEPGADPFVRPGDTVVAGQQVGIIEAMKLMIPVEAERGGRVREI
EEEEEECCEEEEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHEEEEEECCCCCCEEEE
LVADTTPVEYGEPLLTLDVATSTGGAS
EEECCCCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
TTSTANGRSTTTANGHGDIGTVLAVLRQEALEVGARGARPVSRVRVTVGDVSLEVDWAG
CCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEEECC
PGGATGSDGPGQHSTPPQANGSGGLGSVSAAPSDTNGSTASGADAGVGAAAPAGPADDDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LAFVIPAHTVGVFYHAPEPGADPFVRPGDTVVAGQQVGIIEAMKLMIPVEAERGGRVREI
EEEEEECCEEEEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHEEEEEECCCCCCEEEE
LVADTTPVEYGEPLLTLDVATSTGGAS
EEECCCCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8102363; 11759840 [H]