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The map label for this gene is tcrA [H]

Identifier: 158315649

GI number: 158315649

Start: 4587682

End: 4588389

Strand: Reverse

Name: tcrA [H]

Synonym: Franean1_3859

Alternate gene names: 158315649

Gene position: 4588389-4587682 (Counterclockwise)

Preceding gene: 158315650

Following gene: 158315648

Centisome position: 51.08

GC content: 71.89

Gene sequence:

>708_bases
GTGCGGGTACTGGTCGTGGAGGACGAGGAGCGCACCGCGGACCTGCTCCGCCGGGGCCTTACCGAAGCGGGTTACGCCGT
CGACCTGGTGCACGACGGCACGGACGCGGTCTGGCAGGCCGGCGAGATCTCCTACGACGCCATCGTGCTCGACCTGATGC
TGCCCGGCCTCGACGGCTTCGAGGTCTGCCGCCGGCTCCGGGCGGCCCGGCGGTGGTCCCCGATCCTGATGCTCACCGCC
CGCGGCGACGTCGACGACCGCATCCACGGCCTCGACGCCGGCGCCGACGACTACCTCGCCAAGCCGTTCAGCTTCGGTGA
GCTGACGGCCCGGCTCCGCGCGCTGATCCGCCGCGGTGCCGTCGAGCGGCCGGCCACGCTGCGGGTCGGCGACATCCACC
TCGACCCCGCCGCGCGGAGCGTGCAGCGGGCCGGCGAGCCCGTCGACCTGTCGGCCAAGGAGTTCTCGCTGCTGGAGCTG
CTGATGCGGCGCCCCGGCGAGGTTCTTACCAGGAGCTACATCCTGGATCACATGTGGGACCTCGGCTACGACGGCACGTC
CAACGTGGTCGACCAGTATGTGCGGTACCTGCGCAGGAAGATCGACCCGGCGGACGGCCTGTCGCGCATCGAGACGGTCC
GCGGCGCCGGCTACCGCCTCCGCACCGAGACCACCGACACAGCCGACACAGCCGAGACGGGGACGTAG

Upstream 100 bases:

>100_bases
CGGCGTCCCCGGCGTCCCCGGCGTCCCCGGCGTCCCCGGCGTGACGATCGGCCCATCCGGCGCGACGGCCGACACGGCGC
CGGCCTTCTACGATCGAGCG

Downstream 100 bases:

>100_bases
CGCCCGTGCCGCTGCGGGTACGACTGACCCTGCTGTTCGTCCTGGGCACCACGCTGGTGCTCGCGGCCGCCGGCGTGCTG
TTCTACGCGCTGCTGCGCAC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MRVLVVEDEERTADLLRRGLTEAGYAVDLVHDGTDAVWQAGEISYDAIVLDLMLPGLDGFEVCRRLRAARRWSPILMLTA
RGDVDDRIHGLDAGADDYLAKPFSFGELTARLRALIRRGAVERPATLRVGDIHLDPAARSVQRAGEPVDLSAKEFSLLEL
LMRRPGEVLTRSYILDHMWDLGYDGTSNVVDQYVRYLRRKIDPADGLSRIETVRGAGYRLRTETTDTADTAETGT

Sequences:

>Translated_235_residues
MRVLVVEDEERTADLLRRGLTEAGYAVDLVHDGTDAVWQAGEISYDAIVLDLMLPGLDGFEVCRRLRAARRWSPILMLTA
RGDVDDRIHGLDAGADDYLAKPFSFGELTARLRALIRRGAVERPATLRVGDIHLDPAARSVQRAGEPVDLSAKEFSLLEL
LMRRPGEVLTRSYILDHMWDLGYDGTSNVVDQYVRYLRRKIDPADGLSRIETVRGAGYRLRTETTDTADTAETGT
>Mature_235_residues
MRVLVVEDEERTADLLRRGLTEAGYAVDLVHDGTDAVWQAGEISYDAIVLDLMLPGLDGFEVCRRLRAARRWSPILMLTA
RGDVDDRIHGLDAGADDYLAKPFSFGELTARLRALIRRGAVERPATLRVGDIHLDPAARSVQRAGEPVDLSAKEFSLLEL
LMRRPGEVLTRSYILDHMWDLGYDGTSNVVDQYVRYLRRKIDPADGLSRIETVRGAGYRLRTETTDTADTAETGT

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=47.0588235294118, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=43.1818181818182, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=43.1818181818182, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=38.0530973451327, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=39.7321428571429, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=39.8230088495575, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=38.8392857142857, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=37.219730941704, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=40.625, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=34.4036697247706, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=34.5132743362832, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=33.1858407079646, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=31.5789473684211, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=32.6086956521739, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=127, Percent_Identity=32.2834645669291, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=33.9130434782609, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=30.5785123966942, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790299, Length=129, Percent_Identity=26.3565891472868, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26228; Mature: 26228

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVVEDEERTADLLRRGLTEAGYAVDLVHDGTDAVWQAGEISYDAIVLDLMLPGLDGF
CEEEEECCCHHHHHHHHHCCHHCCCEEEEEECCCHHHHCCCCCCHHHHHEEHHHCCCCHH
EVCRRLRAARRWSPILMLTARGDVDDRIHGLDAGADDYLAKPFSFGELTARLRALIRRGA
HHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCC
VERPATLRVGDIHLDPAARSVQRAGEPVDLSAKEFSLLELLMRRPGEVLTRSYILDHMWD
CCCCCEEEEEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LGYDGTSNVVDQYVRYLRRKIDPADGLSRIETVRGAGYRLRTETTDTADTAETGT
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLVVEDEERTADLLRRGLTEAGYAVDLVHDGTDAVWQAGEISYDAIVLDLMLPGLDGF
CEEEEECCCHHHHHHHHHCCHHCCCEEEEEECCCHHHHCCCCCCHHHHHEEHHHCCCCHH
EVCRRLRAARRWSPILMLTARGDVDDRIHGLDAGADDYLAKPFSFGELTARLRALIRRGA
HHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCC
VERPATLRVGDIHLDPAARSVQRAGEPVDLSAKEFSLLELLMRRPGEVLTRSYILDHMWD
CCCCCEEEEEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LGYDGTSNVVDQYVRYLRRKIDPADGLSRIETVRGAGYRLRTETTDTADTAETGT
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]