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The map label for this gene is yngJ [H]

Identifier: 158315484

GI number: 158315484

Start: 4366323

End: 4367636

Strand: Reverse

Name: yngJ [H]

Synonym: Franean1_3689

Alternate gene names: 158315484

Gene position: 4367636-4366323 (Counterclockwise)

Preceding gene: 158315485

Following gene: 158315483

Centisome position: 48.63

GC content: 72.37

Gene sequence:

>1314_bases
ATGACGTCCGACATCAGCACCGGCACCGGCTCGGCCGCCGGCGCGGCGAACGCGGAAGCCACGGAGAGCGTCGCGGACTT
CCGCCGGCGGGCGCGGACGTGGATCCGCGCCAACCTGCGCCCACTCGAACACAACGAGGGCGCCGGCGTCATGCGGGCGG
ACACGACGGACGAGGAGGAGCTCGCCGCCGTCGCCCGCGAGCGGCAGATCCAGCGGATGCTGTTCGACGCCGGCCTCGCC
GGCATCTGCTTCCCGCGCGAGTACGGCGGGCAGGGCCTGTCGCCGGAGCACCAGCGGGCGTTCAACGAGGAGATCACCGG
CTACGAGTACCCCGGCCGGCTGCAGGCGCCGACGTTCTCGCCGTGCGCCGCGGTGCTCCTCGAGTTCGGCACACCGGAGC
AGAAGAGCAGGCACCTCCCCGCCATCCTCAAGGGCGAGGAGATCTGGATGCAGTTCCTCTCCGAGCCGAGCAGCGGCTCG
GACGTCGCCGGCGCGCTGACCACCGCCGTGCGCGAGGGCGACGACTGGATCCTCAACGGCTCGAAGATCTGGACGACCGG
GGCCTGGTGGTCGGACTGGGCGCTCTGCCTGGCCCGCACGAACTGGGACGTCCCGAAGCACCGCGGGCTCACCGTGTTCA
TCATGCCGCTGCGCCAGCCCGGCATCGACGTCCAGCGCATCGAGATGCTCAACGGCAACAAGGAGTTCTGCCAGGAGTTC
ATCACCGACGTCCGGGTCCCCGACACCGACCGCATCGGCGACGTCGACAACGGCTGGACCGTCGGCACCCGGTGGATGTT
CCACGAGCGGATGCTGCACAACTCCCCGTTCGTCACGGTGCCCGCCGGCTGGTCCTACGGCGGCGTCGACGCCACCGTCC
TGGTGGACGTCGCCCGCGACGCCGGCCGCCTCGACGAGCCGCGGGTACGGGACCTCATCGGCGAGGGCCGGGTACTCGAC
CTGGTCCGCGAGTCGCTGCAGGGCCGGATCGGCCGCGGCGTCGTCTCCCGCCGGATGCCCGACCAGTCGGCCGCCATCGG
GCGCCTGTTCGCCGGCATCGCCTCCACCCGCGTCACCAGCATGGCGTACGACATCGCCGGCTCGGCGGGCGCGGCCTGGA
GCGCCGAGGACGGCGCGGTCGCCGAGTGCGGGAACGACTTCCTCCTGCGCCAGACCACCTGCATCGGCGGCGGGACCACC
GAGATGGCCCGCAACGTGATCAGCGAGCGTGTCCTCGGCATGCCCCGCGAGCCCGCCCTCGACCGTGACCGTGCCTTCCG
CGACGTGCCCCGCGGGGGATCCGGCCGCTCCTGA

Upstream 100 bases:

>100_bases
TGTACCTGCGCCGCGTCACCGTGAACCGGGCGCTGTGCGGCACGCCGGCCGAGCACCGCCAGCGCGTCGCCGCCGTCGTC
GAGCACCTCAAGGAGCGGGC

Downstream 100 bases:

>100_bases
CCAGGAGGTGTGATGCCCACCCACGACATTCCGGTGTTCGACGCCGACAACCACCTGTACGAGACCCAGGACGCGCTCAC
CAAGTTCCTGCCGGCGCGCT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTSDISTGTGSAAGAANAEATESVADFRRRARTWIRANLRPLEHNEGAGVMRADTTDEEELAAVARERQIQRMLFDAGLA
GICFPREYGGQGLSPEHQRAFNEEITGYEYPGRLQAPTFSPCAAVLLEFGTPEQKSRHLPAILKGEEIWMQFLSEPSSGS
DVAGALTTAVREGDDWILNGSKIWTTGAWWSDWALCLARTNWDVPKHRGLTVFIMPLRQPGIDVQRIEMLNGNKEFCQEF
ITDVRVPDTDRIGDVDNGWTVGTRWMFHERMLHNSPFVTVPAGWSYGGVDATVLVDVARDAGRLDEPRVRDLIGEGRVLD
LVRESLQGRIGRGVVSRRMPDQSAAIGRLFAGIASTRVTSMAYDIAGSAGAAWSAEDGAVAECGNDFLLRQTTCIGGGTT
EMARNVISERVLGMPREPALDRDRAFRDVPRGGSGRS

Sequences:

>Translated_437_residues
MTSDISTGTGSAAGAANAEATESVADFRRRARTWIRANLRPLEHNEGAGVMRADTTDEEELAAVARERQIQRMLFDAGLA
GICFPREYGGQGLSPEHQRAFNEEITGYEYPGRLQAPTFSPCAAVLLEFGTPEQKSRHLPAILKGEEIWMQFLSEPSSGS
DVAGALTTAVREGDDWILNGSKIWTTGAWWSDWALCLARTNWDVPKHRGLTVFIMPLRQPGIDVQRIEMLNGNKEFCQEF
ITDVRVPDTDRIGDVDNGWTVGTRWMFHERMLHNSPFVTVPAGWSYGGVDATVLVDVARDAGRLDEPRVRDLIGEGRVLD
LVRESLQGRIGRGVVSRRMPDQSAAIGRLFAGIASTRVTSMAYDIAGSAGAAWSAEDGAVAECGNDFLLRQTTCIGGGTT
EMARNVISERVLGMPREPALDRDRAFRDVPRGGSGRS
>Mature_436_residues
TSDISTGTGSAAGAANAEATESVADFRRRARTWIRANLRPLEHNEGAGVMRADTTDEEELAAVARERQIQRMLFDAGLAG
ICFPREYGGQGLSPEHQRAFNEEITGYEYPGRLQAPTFSPCAAVLLEFGTPEQKSRHLPAILKGEEIWMQFLSEPSSGSD
VAGALTTAVREGDDWILNGSKIWTTGAWWSDWALCLARTNWDVPKHRGLTVFIMPLRQPGIDVQRIEMLNGNKEFCQEFI
TDVRVPDTDRIGDVDNGWTVGTRWMFHERMLHNSPFVTVPAGWSYGGVDATVLVDVARDAGRLDEPRVRDLIGEGRVLDL
VRESLQGRIGRGVVSRRMPDQSAAIGRLFAGIASTRVTSMAYDIAGSAGAAWSAEDGAVAECGNDFLLRQTTCIGGGTTE
MARNVISERVLGMPREPALDRDRAFRDVPRGGSGRS

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=26.4864864864865, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI226958412, Length=231, Percent_Identity=29.8701298701299, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226958414, Length=213, Percent_Identity=29.5774647887324, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI7656849, Length=373, Percent_Identity=25.7372654155496, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4557231, Length=364, Percent_Identity=26.0989010989011, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI187960098, Length=364, Percent_Identity=26.0989010989011, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI4501859, Length=202, Percent_Identity=29.2079207920792, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI4501857, Length=163, Percent_Identity=28.8343558282209, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI76496475, Length=313, Percent_Identity=28.7539936102236, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4557235, Length=313, Percent_Identity=28.7539936102236, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI21361497, Length=200, Percent_Identity=29, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786223, Length=207, Percent_Identity=28.5024154589372, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081958, Length=361, Percent_Identity=24.0997229916898, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=200, Percent_Identity=36.5, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=358, Percent_Identity=28.2122905027933, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=196, Percent_Identity=32.6530612244898, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=208, Percent_Identity=29.8076923076923, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=343, Percent_Identity=27.6967930029155, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=207, Percent_Identity=28.0193236714976, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=221, Percent_Identity=28.9592760180996, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=196, Percent_Identity=29.5918367346939, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=28.4671532846715, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=230, Percent_Identity=25.6521739130435, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=223, Percent_Identity=25.1121076233184, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17533517, Length=188, Percent_Identity=26.063829787234, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=235, Percent_Identity=30.6382978723404, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=27.5590551181102, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24646207, Length=254, Percent_Identity=27.1653543307087, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24660351, Length=125, Percent_Identity=36.8, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666513, Length=228, Percent_Identity=26.7543859649123, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI281363737, Length=213, Percent_Identity=29.5774647887324, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 47841; Mature: 47710

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDISTGTGSAAGAANAEATESVADFRRRARTWIRANLRPLEHNEGAGVMRADTTDEEE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHH
LAAVARERQIQRMLFDAGLAGICFPREYGGQGLSPEHQRAFNEEITGYEYPGRLQAPTFS
HHHHHHHHHHHHHHHHCCCCCEECCHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PCAAVLLEFGTPEQKSRHLPAILKGEEIWMQFLSEPSSGSDVAGALTTAVREGDDWILNG
HHHHHHHHCCCCHHHCCCCCCEECHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEECC
SKIWTTGAWWSDWALCLARTNWDVPKHRGLTVFIMPLRQPGIDVQRIEMLNGNKEFCQEF
CEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCHHHHHHH
ITDVRVPDTDRIGDVDNGWTVGTRWMFHERMLHNSPFVTVPAGWSYGGVDATVLVDVARD
HHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEHHH
AGRLDEPRVRDLIGEGRVLDLVRESLQGRIGRGVVSRRMPDQSAAIGRLFAGIASTRVTS
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
MAYDIAGSAGAAWSAEDGAVAECGNDFLLRQTTCIGGGTTEMARNVISERVLGMPREPAL
HHHHHCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCC
DRDRAFRDVPRGGSGRS
CHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TSDISTGTGSAAGAANAEATESVADFRRRARTWIRANLRPLEHNEGAGVMRADTTDEEE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHH
LAAVARERQIQRMLFDAGLAGICFPREYGGQGLSPEHQRAFNEEITGYEYPGRLQAPTFS
HHHHHHHHHHHHHHHHCCCCCEECCHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PCAAVLLEFGTPEQKSRHLPAILKGEEIWMQFLSEPSSGSDVAGALTTAVREGDDWILNG
HHHHHHHHCCCCHHHCCCCCCEECHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEECC
SKIWTTGAWWSDWALCLARTNWDVPKHRGLTVFIMPLRQPGIDVQRIEMLNGNKEFCQEF
CEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCHHHHHHH
ITDVRVPDTDRIGDVDNGWTVGTRWMFHERMLHNSPFVTVPAGWSYGGVDATVLVDVARD
HHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEHHH
AGRLDEPRVRDLIGEGRVLDLVRESLQGRIGRGVVSRRMPDQSAAIGRLFAGIASTRVTS
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
MAYDIAGSAGAAWSAEDGAVAECGNDFLLRQTTCIGGGTTEMARNVISERVLGMPREPAL
HHHHHCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCC
DRDRAFRDVPRGGSGRS
CHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]