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The map label for this gene is lip2 [H]

Identifier: 158315442

GI number: 158315442

Start: 4321573

End: 4322580

Strand: Reverse

Name: lip2 [H]

Synonym: Franean1_3646

Alternate gene names: 158315442

Gene position: 4322580-4321573 (Counterclockwise)

Preceding gene: 158315443

Following gene: 158315439

Centisome position: 48.12

GC content: 62.6

Gene sequence:

>1008_bases
GTGGGTACTTTGGATCATTCGATGCCAGTCATGGATGAGGAATGCGCGGCCGCGTGGCAGCTTATTCTCGACAAGTACTT
CGGTGGAGCAGCCGGAAGGATAGACATCACCGAGGACATCATTCCCAAAGCACGTGCCCACAAAATGCCGAGCCGCGAAA
TGCTACTCGAAGCATTCCCCTTTACCGAGGAGGAACACACGATCCCAGGGCCAGAATCAGAGATCACCATCTCTGTTTTC
ACACCCATTGATCACGGCGGCACCGGCCCGGGAATTTTCTGGATTCATGGTGGTGGAATGGTCACTGGCGACCGTTTCGG
GGTTGTTCCGGCGCTTCGGCTTGCGATGGCGACCGCCGCCGTCGTTGTTTCCGTCGAATATCGGCTCGCTCCTGAGTATC
CCGACCCCGCGCCCGTGGACGACTGCTACGCCGCTCTACTCTGGACCTTTGATCATGCTGACGAACTCGGGATCGGCGCC
AGTACGCTCGTCCTCGCTGGCGGCAGCGCCGGTGGTGGCATTGCCGCTGGCACAGCACTTCGCGTGCGCGACAACGGCGG
GCCGCGCATCGCCGGAATGCTGTTGTCGTGCCCGATGCTAGACGACCGGATGCACACTGCCTCGGCCCACATGACCGGCG
TACTCCCCTGGAGCCGTACCAGTAACGAGACCGGGTGGCGCATGCTGCTGGGGGATCGTGCCGGCACCGACAATGTATCC
ATCTACGCTGCGCCCGGCCGAGCGACCGACCTGTCCGGGCTCCCTCCAACCTTCATCGACGTCGGCACCGTCGATCTCTT
CCGCGACGAGGACGTTGCCTTTGCCTCAACGATCTGGGCGTGCGGCGGCGATGCGGAGATCCATGTCTGGCCCGGCGGAT
TTCACGGCTATGAGGACTGCGCGCCTAACGCCCCGCTCGCCATAGACACTCTCGTAGCCCGCGAACGCTGGTTGGCGCGA
GTCCTCAGTCGTGCCCGTAGCCACGCCACCCAGGCCAACAGCCTTTAG

Upstream 100 bases:

>100_bases
ACCGAGCCGCCGATCGGACGACTTGCGCGCGATAGTACCGCAATGGTAACGTCACTTCCGGGTCACTATCGCGCGCTAGC
GACGTGACGTACAGGGCGAG

Downstream 100 bases:

>100_bases
GAACCTCCAGGTTTCCGCGACATGGCCGGAGGACAGGCTTGCGGCCTTACTTTCGACAGGAGTTCCGGACGCTGCTGCCG
GATGCCGAAGGCATCGCCCG

Product: alpha/beta hydrolase domain-containing protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MGTLDHSMPVMDEECAAAWQLILDKYFGGAAGRIDITEDIIPKARAHKMPSREMLLEAFPFTEEEHTIPGPESEITISVF
TPIDHGGTGPGIFWIHGGGMVTGDRFGVVPALRLAMATAAVVVSVEYRLAPEYPDPAPVDDCYAALLWTFDHADELGIGA
STLVLAGGSAGGGIAAGTALRVRDNGGPRIAGMLLSCPMLDDRMHTASAHMTGVLPWSRTSNETGWRMLLGDRAGTDNVS
IYAAPGRATDLSGLPPTFIDVGTVDLFRDEDVAFASTIWACGGDAEIHVWPGGFHGYEDCAPNAPLAIDTLVARERWLAR
VLSRARSHATQANSL

Sequences:

>Translated_335_residues
MGTLDHSMPVMDEECAAAWQLILDKYFGGAAGRIDITEDIIPKARAHKMPSREMLLEAFPFTEEEHTIPGPESEITISVF
TPIDHGGTGPGIFWIHGGGMVTGDRFGVVPALRLAMATAAVVVSVEYRLAPEYPDPAPVDDCYAALLWTFDHADELGIGA
STLVLAGGSAGGGIAAGTALRVRDNGGPRIAGMLLSCPMLDDRMHTASAHMTGVLPWSRTSNETGWRMLLGDRAGTDNVS
IYAAPGRATDLSGLPPTFIDVGTVDLFRDEDVAFASTIWACGGDAEIHVWPGGFHGYEDCAPNAPLAIDTLVARERWLAR
VLSRARSHATQANSL
>Mature_334_residues
GTLDHSMPVMDEECAAAWQLILDKYFGGAAGRIDITEDIIPKARAHKMPSREMLLEAFPFTEEEHTIPGPESEITISVFT
PIDHGGTGPGIFWIHGGGMVTGDRFGVVPALRLAMATAAVVVSVEYRLAPEYPDPAPVDDCYAALLWTFDHADELGIGAS
TLVLAGGSAGGGIAAGTALRVRDNGGPRIAGMLLSCPMLDDRMHTASAHMTGVLPWSRTSNETGWRMLLGDRAGTDNVSI
YAAPGRATDLSGLPPTFIDVGTVDLFRDEDVAFASTIWACGGDAEIHVWPGGFHGYEDCAPNAPLAIDTLVARERWLARV
LSRARSHATQANSL

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540028, Length=134, Percent_Identity=34.3283582089552, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996133, Length=130, Percent_Identity=35.3846153846154, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 35652; Mature: 35521

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTLDHSMPVMDEECAAAWQLILDKYFGGAAGRIDITEDIIPKARAHKMPSREMLLEAFP
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECHHHHCCCHHHHCCCCHHHHHHHCC
FTEEEHTIPGPESEITISVFTPIDHGGTGPGIFWIHGGGMVTGDRFGVVPALRLAMATAA
CCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHE
VVVSVEYRLAPEYPDPAPVDDCYAALLWTFDHADELGIGASTLVLAGGSAGGGIAAGTAL
EEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEECCCEE
RVRDNGGPRIAGMLLSCPMLDDRMHTASAHMTGVLPWSRTSNETGWRMLLGDRAGTDNVS
EEECCCCCEEEHHEEECCCCCCHHHHCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCEE
IYAAPGRATDLSGLPPTFIDVGTVDLFRDEDVAFASTIWACGGDAEIHVWPGGFHGYEDC
EEECCCCCCCCCCCCCCEEECCEEEEECCCCCEEEHEEEECCCCCEEEEECCCCCCHHHC
APNAPLAIDTLVARERWLARVLSRARSHATQANSL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GTLDHSMPVMDEECAAAWQLILDKYFGGAAGRIDITEDIIPKARAHKMPSREMLLEAFP
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECHHHHCCCHHHHCCCCHHHHHHHCC
FTEEEHTIPGPESEITISVFTPIDHGGTGPGIFWIHGGGMVTGDRFGVVPALRLAMATAA
CCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHE
VVVSVEYRLAPEYPDPAPVDDCYAALLWTFDHADELGIGASTLVLAGGSAGGGIAAGTAL
EEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEECCCEE
RVRDNGGPRIAGMLLSCPMLDDRMHTASAHMTGVLPWSRTSNETGWRMLLGDRAGTDNVS
EEECCCCCEEEHHEEECCCCCCHHHHCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCEE
IYAAPGRATDLSGLPPTFIDVGTVDLFRDEDVAFASTIWACGGDAEIHVWPGGFHGYEDC
EEECCCCCCCCCCCCCCEEECCEEEEECCCCCEEEHEEEECCCCCEEEEECCCCCCHHHC
APNAPLAIDTLVARERWLARVLSRARSHATQANSL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]