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The map label for this gene is metE [H]

Identifier: 158315299

GI number: 158315299

Start: 4162485

End: 4162649

Strand: Direct

Name: metE [H]

Synonym: Franean1_3499

Alternate gene names: 158315299

Gene position: 4162485-4162649 (Clockwise)

Preceding gene: 158315296

Following gene: 158315301

Centisome position: 46.34

GC content: 72.73

Gene sequence:

>165_bases
GTGGAGGAGGTCACCGGGCACCTGGGCGTCGCCACCGGCGCCTTCCCGGCCCGGCGGCTGTGGGTCAACCCGGACTGCAG
GCTCAAGACCCGTGGGTACCCCGAGGTCCGGGCGACCCTCACCAACCTGGTCGCCGCGGCCCGCCAGGTGAGAACACAGC
TCTGA

Upstream 100 bases:

>100_bases
CGCGACGAGGTCGCCGGCATCGAGGTCGCCGGCATCGGGGTGATCCAGGTCGACGAGCCCGCCCTGCGCGAGACCCTGCC
GCTCACCGCGGGTGCCCTCG

Downstream 100 bases:

>100_bases
GTCTCGCCCGCGGGGTGGGGGGGTGTGCCGACCCCACACCCCGCGGTGAGCCGACTCCCCTCGGGCCCGGCCCTGTGAGG
CTCGTCAGCCGGCGGTTTCG

Product: putative methionine synthase

Products: NA

Alternate protein names: Cobalamin-independent methionine synthase; Methionine synthase, vitamin-B12 independent isozyme [H]

Number of amino acids: Translated: 54; Mature: 54

Protein sequence:

>54_residues
MEEVTGHLGVATGAFPARRLWVNPDCRLKTRGYPEVRATLTNLVAAARQVRTQL

Sequences:

>Translated_54_residues
MEEVTGHLGVATGAFPARRLWVNPDCRLKTRGYPEVRATLTNLVAAARQVRTQL
>Mature_54_residues
MEEVTGHLGVATGAFPARRLWVNPDCRLKTRGYPEVRATLTNLVAAARQVRTQL

Specific function: Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation [H]

COG id: COG0620

COG function: function code E; Methionine synthase II (cobalamin-independent)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the vitamin-B12 independent methionine synthase family [H]

Homologues:

Organism=Escherichia coli, GI2367304, Length=51, Percent_Identity=54.9019607843137, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: 45,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013215
- InterPro:   IPR006276
- InterPro:   IPR002629 [H]

Pfam domain/function: PF08267 Meth_synt_1; PF01717 Meth_synt_2 [H]

EC number: =2.1.1.14 [H]

Molecular weight: Translated: 5992; Mature: 5992

Theoretical pI: Translated: 11.22; Mature: 11.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEVTGHLGVATGAFPARRLWVNPDCRLKTRGYPEVRATLTNLVAAARQVRTQL
CCCCCCCCCCCCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEEVTGHLGVATGAFPARRLWVNPDCRLKTRGYPEVRATLTNLVAAARQVRTQL
CCCCCCCCCCCCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA