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The map label for this gene is uhpA [C]

Identifier: 158315290

GI number: 158315290

Start: 4149716

End: 4152568

Strand: Reverse

Name: uhpA [C]

Synonym: Franean1_3490

Alternate gene names: 158315290

Gene position: 4152568-4149716 (Counterclockwise)

Preceding gene: 158315291

Following gene: 158315288

Centisome position: 46.23

GC content: 77.43

Gene sequence:

>2853_bases
ATGACCACAGCCGCGATGACCACCGCCGAGCTCACTGCGACGGGTGCGCGCGGCACCGTCCGAACAGCGGAGCACGGCCG
GATCCTGAACGTGCTCGAGGGCGCGGACGGCGGTGGCCCGGCGATCGTGGAGCTCACCGGCGATCCCGGCTACGGCAAGA
CCCGGCTGCTGACGGCCGTGGCGGACGAGGCCCGCAAGCGTGGCGTCGACGTGCTGCGGGGCAGGTCGCTCGAGACCCGC
CGGCACCGGCCCTTCCACCCGTTCATCGACGCCTTCAGCACCTGGCGGCCCACCGGCGCCGGGCCGCTGCCGCAGGCCAC
CGCGTTCGTCCAGTCCCTGGCGACCGCCGGTGACATGCTCGCCGACACCGAGACCGGCCGCTGCCGGCTCTTCGCCGAGC
TGCGGTCGCTGCTGGAGGAGACACTGGCGGCGGCGCCCGACCCGCTGCTGCTGCTGCTCGACGACGTGCACTTCGCCGAC
CGGGCGTCGGTCGAGCTGCTCGAGATCCTGACGCGTTGGCCGCTGGGGCAGCCGCTGTCGGTCGTGGTGGCGCATCGCCG
GCGTCAGATGTCCTCCTGGCTGCAGGTCACCCTGCAGCAGGGCGTCGAGGTGGGCGCGGTGGACCAGGTGGCGTTGCCGG
CGCTCAGCCTGCGCCAGAGCGCCGAGCTTCTCGGGCTCGCGGTCACCGCGCCGGGGCTGGCCGACCTGCACGAGCGCAGT
GCCGGCAATCCGCTCTACCTGACGGCGTTGGCCGAGCGGGAGCGCGGCCTGAACGGAGTGGACCGGACCGGCCCGGACCC
GACCGGCGCGGGTGGCCACGACCCGGCCGGCGAGCCGCCCGACCTGTGGACGCGCAGCGCGCTCGGCGCCCGGCTGCTGG
CCGAGACCGTGCATCTCGATGCCCGCCAGCGGCTGGTCGCGCACGCGGCGGCCGTGCTCGGCGACACCTTCTCGGTCGAC
GCCGTGGCGGCCGTCGCGCAGCTCGACCGGGAGGAGGCCTGCCAGGCGCTCGGCCAGCTGCGCGGCCGCGACCTGGTGCG
CATGGTGCCGGGCGGCGAGCTGGTCTTCCGCCACCCGCTGCTGGGCAGCTGTGTCTACGGGGAGACCGACTCCTGCTGGC
GGGCCGGGGCGCACCGACGCGCCCTCGAGCACCTCCGGTCGACGTTCGCCGCGCCGGCCGTGCTCGCCCGGCATGTCGAG
CGCTCCGGATCGCACAGCCATGCCCTGGACCTGACGGTGCTGCTCGACGCGACCCGGGCGGCCGTGCAGAGCGAGCAGGG
CACCGAGGCCGCCCACTGGCTCAGCGCCGCCCTGCGGCTGCGCCGCGCCGCCCCGGAAACCCCGAACGGCACCGGCAGCA
CCGGTGAGACGGCCGGTGCGGCCGGTGCGGGGCTCCCGCCGGTCGGCCCGGAGGTCTGGCGCCCGGTGATCGACCTGCTC
GCCCGCCCCGACGCCGTCGCGCGCCTGCGCGCCCTCGGCCAGGAGGTCCTGAACACCCCGGCCGCGTACGGGCCGGCCGG
CCGGGTGGGCACGGCGGCGCACCTGGCGATGGTCTCGGCCTCGCTGGGCTGCCACGACCACGCCGTCGCCCTGCTGTCGA
TCGCGCTCGCCGACGCCCGGGGGCCGGCCGAGGAGGGGCGCGTGCAGCTGTTCGCCCAGCTCGCCCGCATCGTCTCCGGA
GGCATACCGAGCCGCGCCGAGGTGGACGCGCTGACCGGGCCGGAGCCGGCCGGCGACCCGCTGACCCGGGCCGGCGGGCT
CGCGGTCCGGGCGCTGTGCGCCGCGCTCACCACCGACCGCGGCGCCACCGGGAACAGGTCCGCGGGCGCGGAGGCGGACG
CGGCGGCCGCCGCGCTCGACGCCCTGGCGGTGAACGGCCCGGACCCCTCGGGCCCGGAGCTGTACTTCCTGCAGTGCCTG
GGCTGGACGGAGGCGATGCTCGGTCGCTACGACAGCGCGCACGCCAGGATCACCCGCGCGGTGCGCGGCGCCCGCAAGCA
CGGCGAGCGCCACCTGCTGCCCGCCCTGCTCAACAGCCTCGCCTACATCCACTACCAGTCGGGGCGCCGGAGCGAGGCGA
TCGAGGTCACCCGGGAGGCCCAGCGCGTGTCGCAGCGGGCCGGTCGCGCCGACCAGGTGGCACTGGCCCAGGCCGTGGCC
ACGGCCGCCTGGGCCGGGCTGGGGCGCTCCCCCACGTTCGGCCCGGAGCTGCCGGAGGGCGTGCACGCCGACGCGCCCCG
CACGCCGCTGACCGCGCTGCTGTTCGCCGAGGCCGCGCTGGCCGCCGGCGACGGACCGGCCGCCCTGGCCCTGCTGGGGT
CGAAGCGGGAGACCTGGCGGGTCGCCGAGCCGATCCCGGTGCTGGGTGCCCGCATCTTCGAGGTGCTGGCCGCCGCCGCG
CTGCTGGCCGGGGAGGATCCACGCCCGTGGGCGGCCCGAGCGGCCGAGGAGGCCGCCCGGGTCGGGCTGCCCGAGCAGCG
GGGCCACGCGCTGCTCGCCCGCGGCTACGCGCTGGGTCGCGGCCCGGAGGCCGACCGGTGCTACGCCGAGGCGGCCGGCC
TGCTGGCGGGCGCGCCCGCCGGCGGCCGGGCCCGGACGTTCGCGCGGTCGGCTCAGCAACGGCGCCACCGCCCCGGCCCC
GACCCGCTGGTCGAGCTCACCACCAGGGAGCAGGAGGTCGCCCAGCTCGCCGGCCAGGGGCTGCGGACCCGGGACATCGC
CAGCCGGCTGCGGGTGAGCCCGCGCACCGTCGACACCCACCTCTCCCACATCTACGACAAGCTCGGCATGAGCTCGCGGG
TCGAGCTGGCCCGGTTGCTGTCCCCGGTCCCGCTGGTGCCCCCGGGCCACTGA

Upstream 100 bases:

>100_bases
GCGATCACCACGGGCATGCATGATTCGTGCCCCGGCCACCACAGCGCCGTCGTCCGTCGAAGAATGTCCGGAACCGCGTC
GAGAAGGAGAGTCACAGGGC

Downstream 100 bases:

>100_bases
TGTCGCCGACCGACTGATGCCGCCGATCCGCTGACCGGCGCGCGGCGCGCAACGGCGCGCGCCGCGCGTGACACCGTGTG
ACACCACGGGACGGCTCGGC

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 950; Mature: 949

Protein sequence:

>950_residues
MTTAAMTTAELTATGARGTVRTAEHGRILNVLEGADGGGPAIVELTGDPGYGKTRLLTAVADEARKRGVDVLRGRSLETR
RHRPFHPFIDAFSTWRPTGAGPLPQATAFVQSLATAGDMLADTETGRCRLFAELRSLLEETLAAAPDPLLLLLDDVHFAD
RASVELLEILTRWPLGQPLSVVVAHRRRQMSSWLQVTLQQGVEVGAVDQVALPALSLRQSAELLGLAVTAPGLADLHERS
AGNPLYLTALAERERGLNGVDRTGPDPTGAGGHDPAGEPPDLWTRSALGARLLAETVHLDARQRLVAHAAAVLGDTFSVD
AVAAVAQLDREEACQALGQLRGRDLVRMVPGGELVFRHPLLGSCVYGETDSCWRAGAHRRALEHLRSTFAAPAVLARHVE
RSGSHSHALDLTVLLDATRAAVQSEQGTEAAHWLSAALRLRRAAPETPNGTGSTGETAGAAGAGLPPVGPEVWRPVIDLL
ARPDAVARLRALGQEVLNTPAAYGPAGRVGTAAHLAMVSASLGCHDHAVALLSIALADARGPAEEGRVQLFAQLARIVSG
GIPSRAEVDALTGPEPAGDPLTRAGGLAVRALCAALTTDRGATGNRSAGAEADAAAAALDALAVNGPDPSGPELYFLQCL
GWTEAMLGRYDSAHARITRAVRGARKHGERHLLPALLNSLAYIHYQSGRRSEAIEVTREAQRVSQRAGRADQVALAQAVA
TAAWAGLGRSPTFGPELPEGVHADAPRTPLTALLFAEAALAAGDGPAALALLGSKRETWRVAEPIPVLGARIFEVLAAAA
LLAGEDPRPWAARAAEEAARVGLPEQRGHALLARGYALGRGPEADRCYAEAAGLLAGAPAGGRARTFARSAQQRRHRPGP
DPLVELTTREQEVAQLAGQGLRTRDIASRLRVSPRTVDTHLSHIYDKLGMSSRVELARLLSPVPLVPPGH

Sequences:

>Translated_950_residues
MTTAAMTTAELTATGARGTVRTAEHGRILNVLEGADGGGPAIVELTGDPGYGKTRLLTAVADEARKRGVDVLRGRSLETR
RHRPFHPFIDAFSTWRPTGAGPLPQATAFVQSLATAGDMLADTETGRCRLFAELRSLLEETLAAAPDPLLLLLDDVHFAD
RASVELLEILTRWPLGQPLSVVVAHRRRQMSSWLQVTLQQGVEVGAVDQVALPALSLRQSAELLGLAVTAPGLADLHERS
AGNPLYLTALAERERGLNGVDRTGPDPTGAGGHDPAGEPPDLWTRSALGARLLAETVHLDARQRLVAHAAAVLGDTFSVD
AVAAVAQLDREEACQALGQLRGRDLVRMVPGGELVFRHPLLGSCVYGETDSCWRAGAHRRALEHLRSTFAAPAVLARHVE
RSGSHSHALDLTVLLDATRAAVQSEQGTEAAHWLSAALRLRRAAPETPNGTGSTGETAGAAGAGLPPVGPEVWRPVIDLL
ARPDAVARLRALGQEVLNTPAAYGPAGRVGTAAHLAMVSASLGCHDHAVALLSIALADARGPAEEGRVQLFAQLARIVSG
GIPSRAEVDALTGPEPAGDPLTRAGGLAVRALCAALTTDRGATGNRSAGAEADAAAAALDALAVNGPDPSGPELYFLQCL
GWTEAMLGRYDSAHARITRAVRGARKHGERHLLPALLNSLAYIHYQSGRRSEAIEVTREAQRVSQRAGRADQVALAQAVA
TAAWAGLGRSPTFGPELPEGVHADAPRTPLTALLFAEAALAAGDGPAALALLGSKRETWRVAEPIPVLGARIFEVLAAAA
LLAGEDPRPWAARAAEEAARVGLPEQRGHALLARGYALGRGPEADRCYAEAAGLLAGAPAGGRARTFARSAQQRRHRPGP
DPLVELTTREQEVAQLAGQGLRTRDIASRLRVSPRTVDTHLSHIYDKLGMSSRVELARLLSPVPLVPPGH
>Mature_949_residues
TTAAMTTAELTATGARGTVRTAEHGRILNVLEGADGGGPAIVELTGDPGYGKTRLLTAVADEARKRGVDVLRGRSLETRR
HRPFHPFIDAFSTWRPTGAGPLPQATAFVQSLATAGDMLADTETGRCRLFAELRSLLEETLAAAPDPLLLLLDDVHFADR
ASVELLEILTRWPLGQPLSVVVAHRRRQMSSWLQVTLQQGVEVGAVDQVALPALSLRQSAELLGLAVTAPGLADLHERSA
GNPLYLTALAERERGLNGVDRTGPDPTGAGGHDPAGEPPDLWTRSALGARLLAETVHLDARQRLVAHAAAVLGDTFSVDA
VAAVAQLDREEACQALGQLRGRDLVRMVPGGELVFRHPLLGSCVYGETDSCWRAGAHRRALEHLRSTFAAPAVLARHVER
SGSHSHALDLTVLLDATRAAVQSEQGTEAAHWLSAALRLRRAAPETPNGTGSTGETAGAAGAGLPPVGPEVWRPVIDLLA
RPDAVARLRALGQEVLNTPAAYGPAGRVGTAAHLAMVSASLGCHDHAVALLSIALADARGPAEEGRVQLFAQLARIVSGG
IPSRAEVDALTGPEPAGDPLTRAGGLAVRALCAALTTDRGATGNRSAGAEADAAAAALDALAVNGPDPSGPELYFLQCLG
WTEAMLGRYDSAHARITRAVRGARKHGERHLLPALLNSLAYIHYQSGRRSEAIEVTREAQRVSQRAGRADQVALAQAVAT
AAWAGLGRSPTFGPELPEGVHADAPRTPLTALLFAEAALAAGDGPAALALLGSKRETWRVAEPIPVLGARIFEVLAAAAL
LAGEDPRPWAARAAEEAARVGLPEQRGHALLARGYALGRGPEADRCYAEAAGLLAGAPAGGRARTFARSAQQRRHRPGPD
PLVELTTREQEVAQLAGQGLRTRDIASRLRVSPRTVDTHLSHIYDKLGMSSRVELARLLSPVPLVPPGH

Specific function: Appears To Be The Positive Activator Of Uhpt Transcription. [C]

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000767
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 99707; Mature: 99576

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAAMTTAELTATGARGTVRTAEHGRILNVLEGADGGGPAIVELTGDPGYGKTRLLTAV
CCCCHHHHHHHEECCCCCCEEECCCCCEEEHHCCCCCCCCEEEEECCCCCCCHHHHHHHH
ADEARKRGVDVLRGRSLETRRHRPFHPFIDAFSTWRPTGAGPLPQATAFVQSLATAGDML
HHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
ADTETGRCRLFAELRSLLEETLAAAPDPLLLLLDDVHFADRASVELLEILTRWPLGQPLS
HCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHH
VVVAHRRRQMSSWLQVTLQQGVEVGAVDQVALPALSLRQSAELLGLAVTAPGLADLHERS
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHC
AGNPLYLTALAERERGLNGVDRTGPDPTGAGGHDPAGEPPDLWTRSALGARLLAETVHLD
CCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARQRLVAHAAAVLGDTFSVDAVAAVAQLDREEACQALGQLRGRDLVRMVPGGELVFRHPL
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCEEEECCC
LGSCVYGETDSCWRAGAHRRALEHLRSTFAAPAVLARHVERSGSHSHALDLTVLLDATRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHHHHHH
AVQSEQGTEAAHWLSAALRLRRAAPETPNGTGSTGETAGAAGAGLPPVGPEVWRPVIDLL
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ARPDAVARLRALGQEVLNTPAAYGPAGRVGTAAHLAMVSASLGCHDHAVALLSIALADAR
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
GPAEEGRVQLFAQLARIVSGGIPSRAEVDALTGPEPAGDPLTRAGGLAVRALCAALTTDR
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GATGNRSAGAEADAAAAALDALAVNGPDPSGPELYFLQCLGWTEAMLGRYDSAHARITRA
CCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHH
VRGARKHGERHLLPALLNSLAYIHYQSGRRSEAIEVTREAQRVSQRAGRADQVALAQAVA
HHHHHHCCCCHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TAAWAGLGRSPTFGPELPEGVHADAPRTPLTALLFAEAALAAGDGPAALALLGSKRETWR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
VAEPIPVLGARIFEVLAAAALLAGEDPRPWAARAAEEAARVGLPEQRGHALLARGYALGR
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHCCEEHHHCCCCCC
GPEADRCYAEAAGLLAGAPAGGRARTFARSAQQRRHRPGPDPLVELTTREQEVAQLAGQG
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCC
LRTRDIASRLRVSPRTVDTHLSHIYDKLGMSSRVELARLLSPVPLVPPGH
CCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTAAMTTAELTATGARGTVRTAEHGRILNVLEGADGGGPAIVELTGDPGYGKTRLLTAV
CCCHHHHHHHEECCCCCCEEECCCCCEEEHHCCCCCCCCEEEEECCCCCCCHHHHHHHH
ADEARKRGVDVLRGRSLETRRHRPFHPFIDAFSTWRPTGAGPLPQATAFVQSLATAGDML
HHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
ADTETGRCRLFAELRSLLEETLAAAPDPLLLLLDDVHFADRASVELLEILTRWPLGQPLS
HCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHH
VVVAHRRRQMSSWLQVTLQQGVEVGAVDQVALPALSLRQSAELLGLAVTAPGLADLHERS
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHC
AGNPLYLTALAERERGLNGVDRTGPDPTGAGGHDPAGEPPDLWTRSALGARLLAETVHLD
CCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARQRLVAHAAAVLGDTFSVDAVAAVAQLDREEACQALGQLRGRDLVRMVPGGELVFRHPL
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCEEEECCC
LGSCVYGETDSCWRAGAHRRALEHLRSTFAAPAVLARHVERSGSHSHALDLTVLLDATRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHHHHHH
AVQSEQGTEAAHWLSAALRLRRAAPETPNGTGSTGETAGAAGAGLPPVGPEVWRPVIDLL
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ARPDAVARLRALGQEVLNTPAAYGPAGRVGTAAHLAMVSASLGCHDHAVALLSIALADAR
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
GPAEEGRVQLFAQLARIVSGGIPSRAEVDALTGPEPAGDPLTRAGGLAVRALCAALTTDR
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GATGNRSAGAEADAAAAALDALAVNGPDPSGPELYFLQCLGWTEAMLGRYDSAHARITRA
CCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHH
VRGARKHGERHLLPALLNSLAYIHYQSGRRSEAIEVTREAQRVSQRAGRADQVALAQAVA
HHHHHHCCCCHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TAAWAGLGRSPTFGPELPEGVHADAPRTPLTALLFAEAALAAGDGPAALALLGSKRETWR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
VAEPIPVLGARIFEVLAAAALLAGEDPRPWAARAAEEAARVGLPEQRGHALLARGYALGR
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHCCEEHHHCCCCCC
GPEADRCYAEAAGLLAGAPAGGRARTFARSAQQRRHRPGPDPLVELTTREQEVAQLAGQG
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCC
LRTRDIASRLRVSPRTVDTHLSHIYDKLGMSSRVELARLLSPVPLVPPGH
CCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]