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The map label for this gene is pcp [H]

Identifier: 158315235

GI number: 158315235

Start: 4065997

End: 4066383

Strand: Direct

Name: pcp [H]

Synonym: Franean1_3435

Alternate gene names: 158315235

Gene position: 4065997-4066383 (Clockwise)

Preceding gene: 158315234

Following gene: 158315236

Centisome position: 45.27

GC content: 65.63

Gene sequence:

>387_bases
GTGACGAAGGTGCTGGTGTCCGGTTTCGAGCGTTACGGCACAACGCCGGTCGACCCTGCGCAGGGCGTCGCCGAGGCGCT
CGACGGCACGGAGATCAACGATGCGGCGATCATCGGGCTGGTCGTACCGAGCAGATGGTTCGACTGCATCGACGTTGTCA
CCGGCGCTATCGACCGGACCGCCCCAGACCTTGTCGTGATGCTGGGCGAGTATGGCGGACGATCGATGATCACTGTCGAG
CGCATCGCCCAGAACCTCAACGACTCCGCCCGCTACGGGGTGGCCGACAACGGCGGCAGGGTAGCAGTGAGGCTTCGCCT
CGGACCGCCGAGCAGGGTGGTTGGGTTGGTGCTCCTGGTGCTGGTGGGAGCATCCTCACGACCGTAG

Upstream 100 bases:

>100_bases
TGTCCCGTACGTGCATTTCCTCTCAGCCAGCGCGGATGTGGATGCGGCCTTAGCTACGTCCACATCACCTGCTGGGCCGG
CGTGAACGGGGGCGAGGCGA

Downstream 100 bases:

>100_bases
CCGTGTCAGGAGGCCGGTGATGGGTGCGCATACGGTGACGGTCAGCGAGGTGCTCGACGGACATGTGGCGCTGGACATCC
AGTGCCTGGACCGGATCTAT

Product: peptidase C15 pyroglutamyl peptidase I

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MTKVLVSGFERYGTTPVDPAQGVAEALDGTEINDAAIIGLVVPSRWFDCIDVVTGAIDRTAPDLVVMLGEYGGRSMITVE
RIAQNLNDSARYGVADNGGRVAVRLRLGPPSRVVGLVLLVLVGASSRP

Sequences:

>Translated_128_residues
MTKVLVSGFERYGTTPVDPAQGVAEALDGTEINDAAIIGLVVPSRWFDCIDVVTGAIDRTAPDLVVMLGEYGGRSMITVE
RIAQNLNDSARYGVADNGGRVAVRLRLGPPSRVVGLVLLVLVGASSRP
>Mature_127_residues
TKVLVSGFERYGTTPVDPAQGVAEALDGTEINDAAIIGLVVPSRWFDCIDVVTGAIDRTAPDLVVMLGEYGGRSMITVER
IAQNLNDSARYGVADNGGRVAVRLRLGPPSRVVGLVLLVLVGASSRP

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 13465; Mature: 13333

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS01333 PYRASE_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVLVSGFERYGTTPVDPAQGVAEALDGTEINDAAIIGLVVPSRWFDCIDVVTGAIDRT
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCC
APDLVVMLGEYGGRSMITVERIAQNLNDSARYGVADNGGRVAVRLRLGPPSRVVGLVLLV
CCCEEEEECCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHH
LVGASSRP
HHCCCCCC
>Mature Secondary Structure 
TKVLVSGFERYGTTPVDPAQGVAEALDGTEINDAAIIGLVVPSRWFDCIDVVTGAIDRT
CCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCC
APDLVVMLGEYGGRSMITVERIAQNLNDSARYGVADNGGRVAVRLRLGPPSRVVGLVLLV
CCCEEEEECCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHH
LVGASSRP
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]