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The map label for this gene is ycgM [C]

Identifier: 158315116

GI number: 158315116

Start: 3927509

End: 3928285

Strand: Direct

Name: ycgM [C]

Synonym: Franean1_3315

Alternate gene names: 158315116

Gene position: 3927509-3928285 (Clockwise)

Preceding gene: 158315109

Following gene: 158315117

Centisome position: 43.73

GC content: 70.14

Gene sequence:

>777_bases
ATGCTGCTCGGTCGTGCACTGATGGGCGACACCTCGTGCTTCGGCGAGGTGGTGGATGATCGCTTCCACCTCCTCTCCGG
CGGCATGCTGGAGGGGTACCGCCGTGTCGGACGGTCCCTGCCGCTTGCGGATCTTGTTCTCGGCGCGCCCCTGACCGGCG
TTCGGCTCATCGCCGTGATGGGCGGCTTCCTCGAGCCGGGCACGTCGCGCCCGCCGGGGATCCAGCCGATGTGGGTGCCC
AAGGCGTGCGGGTTCGTCGGTGGCGACCGCGCACAGATCCGGGTGCCAGCGGTGCTGACCGGGGCGGTGCAGATGGAGGC
CGAGCTCGCCGTGGTCGTCGGCCGCCCGCTGCGCGGCGCGTCACCGGCCGAAGCGGCCGAAGCCATCTTCGGCTGGACCG
TCTTCAACGACGTCACCGCGGCTGAGTACGTGGCGCCCGGCCTGTGGGCGACGGCGAAGTCGATCGACGGGTTCGCGTCG
TGGGGCCCGTGGATCCGGCGGGATCTCACCGAACGGCGCGTCCTCGAAGGGCTGGCGATCACCGGGACCCTCAACGGGAG
CAAGGTCCAGGCGGGAAACACCCGGTATTTCAGGTTCGCGCCGAGCGAGATCCTGAGCCACATCAGCCATCGGATCAGCC
TCTTTCCCGGCGACGTCGTCACGCTCGGAACGCCGCCGCCAGCCGTTGACGCCGCCGCCGGCGACCACATGGTGTGCGAG
GTGGAGGAGGTTGGCGTCCTGACCAACCAGCTGCTCGCCGCCGGGAGCGAGGAATGA

Upstream 100 bases:

>100_bases
GATGATGAACCGCAGGGCGCCGCCGGCGAACTCACCGGGCGGATGGCCGCGGCTCGCGGCGCCGGCCATCGCGATTCTCC
CGTGCGAGAGGGGCCTGGCA

Downstream 100 bases:

>100_bases
CCGGAGGGGTCCGCCCCGGCCGCCGCCAGCCGGAGACCGGGTTAGACGAGGAGGGGCTGTGACGACGGAGCAGGCGGCGG
AGCCGGCGCTCGATGTGCGG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLLGRALMGDTSCFGEVVDDRFHLLSGGMLEGYRRVGRSLPLADLVLGAPLTGVRLIAVMGGFLEPGTSRPPGIQPMWVP
KACGFVGGDRAQIRVPAVLTGAVQMEAELAVVVGRPLRGASPAEAAEAIFGWTVFNDVTAAEYVAPGLWATAKSIDGFAS
WGPWIRRDLTERRVLEGLAITGTLNGSKVQAGNTRYFRFAPSEILSHISHRISLFPGDVVTLGTPPPAVDAAAGDHMVCE
VEEVGVLTNQLLAAGSEE

Sequences:

>Translated_258_residues
MLLGRALMGDTSCFGEVVDDRFHLLSGGMLEGYRRVGRSLPLADLVLGAPLTGVRLIAVMGGFLEPGTSRPPGIQPMWVP
KACGFVGGDRAQIRVPAVLTGAVQMEAELAVVVGRPLRGASPAEAAEAIFGWTVFNDVTAAEYVAPGLWATAKSIDGFAS
WGPWIRRDLTERRVLEGLAITGTLNGSKVQAGNTRYFRFAPSEILSHISHRISLFPGDVVTLGTPPPAVDAAAGDHMVCE
VEEVGVLTNQLLAAGSEE
>Mature_258_residues
MLLGRALMGDTSCFGEVVDDRFHLLSGGMLEGYRRVGRSLPLADLVLGAPLTGVRLIAVMGGFLEPGTSRPPGIQPMWVP
KACGFVGGDRAQIRVPAVLTGAVQMEAELAVVVGRPLRGASPAEAAEAIFGWTVFNDVTAAEYVAPGLWATAKSIDGFAS
WGPWIRRDLTERRVLEGLAITGTLNGSKVQAGNTRYFRFAPSEILSHISHRISLFPGDVVTLGTPPPAVDAAAGDHMVCE
VEEVGVLTNQLLAAGSEE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=228, Percent_Identity=28.0701754385965, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI40786394, Length=228, Percent_Identity=27.6315789473684, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24663695, Length=159, Percent_Identity=30.8176100628931, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28572127, Length=224, Percent_Identity=25.8928571428571, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27233; Mature: 27233

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLGRALMGDTSCFGEVVDDRFHLLSGGMLEGYRRVGRSLPLADLVLGAPLTGVRLIAVM
CCCCCCHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHH
GGFLEPGTSRPPGIQPMWVPKACGFVGGDRAQIRVPAVLTGAVQMEAELAVVVGRPLRGA
CCCCCCCCCCCCCCCEEECHHHCCCCCCCCCEEEECEEEECCCCEEEEEEEEECCCCCCC
SPAEAAEAIFGWTVFNDVTAAEYVAPGLWATAKSIDGFASWGPWIRRDLTERRVLEGLAI
CHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCCHHCCHHHHHHHHHHHHHCCEEE
TGTLNGSKVQAGNTRYFRFAPSEILSHISHRISLFPGDVVTLGTPPPAVDAAAGDHMVCE
EEECCCCEEECCCEEEEEECHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCCCCCEEEE
VEEVGVLTNQLLAAGSEE
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLGRALMGDTSCFGEVVDDRFHLLSGGMLEGYRRVGRSLPLADLVLGAPLTGVRLIAVM
CCCCCCHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHH
GGFLEPGTSRPPGIQPMWVPKACGFVGGDRAQIRVPAVLTGAVQMEAELAVVVGRPLRGA
CCCCCCCCCCCCCCCEEECHHHCCCCCCCCCEEEECEEEECCCCEEEEEEEEECCCCCCC
SPAEAAEAIFGWTVFNDVTAAEYVAPGLWATAKSIDGFASWGPWIRRDLTERRVLEGLAI
CHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCCHHCCHHHHHHHHHHHHHCCEEE
TGTLNGSKVQAGNTRYFRFAPSEILSHISHRISLFPGDVVTLGTPPPAVDAAAGDHMVCE
EEECCCCEEECCCEEEEEECHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCCCCCEEEE
VEEVGVLTNQLLAAGSEE
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]