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The map label for this gene is fadD11 [H]

Identifier: 158314759

GI number: 158314759

Start: 3458621

End: 3460942

Strand: Direct

Name: fadD11 [H]

Synonym: Franean1_2941

Alternate gene names: 158314759

Gene position: 3458621-3460942 (Clockwise)

Preceding gene: 158314758

Following gene: 158314760

Centisome position: 38.51

GC content: 67.05

Gene sequence:

>2322_bases
ATGCGCGTCAGAGCCCACCGGCAGATAAGCGCTCCTGTCGATGTCGTCTGGGATGTGGTCACCGACCACGAGGGGATGAG
TACCTGGTTCCCCGGTGTCGCCGTCGCCCTGGAACGTCCGGGCGTGCAGGGCGGCATCGGTGCCGTCCGGATCGTCCGGA
TGACGGGCCTCAGCATCCGGGAGCAGGTGACGGACATCGAGCCCGCCCGCCGGCTCGCCTACCGGTGCATCTCCGGGCAC
CCCTTGCGGGACTACCGCGGAGAGATCTTTCTCGCGCCGTCCGGGACCGGTACGAGCCTGACCTGGGTGCTCGACACCTC
GACCCGTTTCCGTTTGGTCGCGTGGCTGCTGGTAAACCAGGCGCGTCTTTTTGCCTGGTCTCTCGCCAGGGCCGCGGAGC
GTTCATCCGCTCTCATCCGGTCCGCCGACACCGATCGGACGAAGGAGCCCGCTGTGCAGCACGTGCAGTCGACGGCGTCG
ACGCAGCAGACGCCCGGCGCAGATTCCAGCCCCGGACCAGCTTCGCTGGCCGAGGCATTCCAGCGCAATGCCAGTCGCGA
CCCACAGGCGTTAGCCTTGAGCACCCCGGACGGGTCAGCGACCCTCACCTGGGGGCAATACGCCGAGCAGGTGCGCGACA
TCGCGGCTGCCCTGCATGCCCACGGCGTCCGGCGCGGCGACAGCGTCGCCCTGATGATGCTCAACCGCCCCGAATTCTAT
CCCATCGACACGGCCGCTATCCATCTCGGCGCGATCCCGTTCTCGATTTACAACACGTCGTCCGCCGAGCAGATCCGGTG
GCTGTTCGCCAGCGCGAAACCGAGCATGGTCTTCTGCGACAGCAGCCACGCCGCTGCGGTGCTGGAGGCAGTCGACGGCG
GCACCGCTGTCAAAGCTGTTGTGTGCGTGGACGGCGACGTCGAGGGGGCGACGACCTCGGTGGAATTTCGGGGCGTCCGC
AGCGACGACTTCGACTTCGAGAGCACCTGGCGTTCGGTGACACCGGACGACGTTCTCACGTTGATCTACACATCCGGCAC
GACGGGGGAGCCGAAAGGCGTCCAGATCACGCACGGCAACATGCTTGCGCAGCTCGCCGCGACCAACACCTTCCTGGAAG
CGGGCCCGGGCGACAGAGTCATCTCCTTCCTGCCCTCGGCGCACATCGCGGACCGGTGGGCTGCGCACTATCTCCAGCTG
GTCTGCGGGACGACCGTCTACCCGCTGGTCGACCGCACTCAGCTGCTCCCGACAATGCTCCGCGTTCGTCCCACTCTGTT
CGGCGCCGTGCCCCAGGTGTGGCAGAAGATCCGTGCTGGGGTGCTGGCGATGATCGACGCAGAAGCCGACGAGGAGCGGC
AGGCGGGCATCCAGCAGACCCTGGCCGTCGGAGCCCGGTACGCGCGAAGCCGCAGCGATGGCACCCTCACGGCCGAGCTC
GAGAGCCTTTTCGCAACGGCCGACACGCAGGTGCTCAGCCATCTGCGTTCCAGGCTCGGCCTGGACCAGGCGCGGATCGT
GATGTCTGGCGCGGCGGCGGTACCCGTGGAGATCGTCGAGTTCTTCAACTCCATCGGGGTTCCGCTCATCGACGGGTGGG
GGATGTCCGAGCTCTCCTGCATGGGCGCGTTCATGCCCAACCACGCGCCGCGCCTGGGATCGGTGGGCATGGCTCTTCCC
GGTGTCCAGGTCCGCCTGGGCGAGGACGGCGAACTGCTCGTGCGCGGACCGATCGTGATGAAGGGCTACCTCGGCCGACC
CGAGCTGACTGCTGAGCTCATTGACGACGAGGGCTGGCTGTACACGGGCGACGTCGCCCGCATCGACGACGAAGGATACA
TTTATATTATTGATCGAAAGAAAGAAATCATTGTCAACTCCAGCGGAAAGAACATCTCGCCAGCGGGCATCGAGGGTCAT
CTGAAAGCGGCGAGTCCCCTTATCGGCCAAGCTGTCGTGATCGGTGAGGCGCGGCCCTTTTTGACCGCGCTGATCGTGCT
CGACGCGGATGCCGCGGGCCAGTACGCGGCCTCCCGCGCACTCCCGGCGGACGCGAGCTCGCTCGCCGCGGACGAGGGAG
TCGTCGCCGCGCTCTCCGCCGCCGTGACCGAGGCGAACACCCACGTCTCGCAGGTCGAGCACGTCCGGAAGTTCGCTGTC
CTCCCCCAGTTCTGGGAGCCGGGAAGCGAGCTGCTTACGCACACGATGAAGCTGCGCCGCAGGCCGATCGGCGCCCGCTA
CGCCGACGTCATCGAGGCGCTCTACCGGCTGCCGCGCGACGAGTCGGTCCTGCGTATCGCGGACGCGGCGTCCGCCTCCT
AG

Upstream 100 bases:

>100_bases
CCACCACCCTGCGGCGGACCCCGCGCACGCTTCGGGTCCTGCGCCTGCTCATGAACGCACGGCACGCTCGGCGCTCAACG
CTTGGAAGGCGGTGATACGG

Downstream 100 bases:

>100_bases
CCGGCTTTTCCCGGAGTCGAACCGGGCCGCCGGCCACCACACACAGCGACGGCTTCGTCGACCAGGGCGCAGCGCCGATA
CAAGGAGAGCAATTGACTAC

Product: AMP-dependent synthetase and ligase

Products: AMP; diphosphate +an acyl-CoA [C]

Alternate protein names: Acyl-CoA synthetase [H]

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MRVRAHRQISAPVDVVWDVVTDHEGMSTWFPGVAVALERPGVQGGIGAVRIVRMTGLSIREQVTDIEPARRLAYRCISGH
PLRDYRGEIFLAPSGTGTSLTWVLDTSTRFRLVAWLLVNQARLFAWSLARAAERSSALIRSADTDRTKEPAVQHVQSTAS
TQQTPGADSSPGPASLAEAFQRNASRDPQALALSTPDGSATLTWGQYAEQVRDIAAALHAHGVRRGDSVALMMLNRPEFY
PIDTAAIHLGAIPFSIYNTSSAEQIRWLFASAKPSMVFCDSSHAAAVLEAVDGGTAVKAVVCVDGDVEGATTSVEFRGVR
SDDFDFESTWRSVTPDDVLTLIYTSGTTGEPKGVQITHGNMLAQLAATNTFLEAGPGDRVISFLPSAHIADRWAAHYLQL
VCGTTVYPLVDRTQLLPTMLRVRPTLFGAVPQVWQKIRAGVLAMIDAEADEERQAGIQQTLAVGARYARSRSDGTLTAEL
ESLFATADTQVLSHLRSRLGLDQARIVMSGAAAVPVEIVEFFNSIGVPLIDGWGMSELSCMGAFMPNHAPRLGSVGMALP
GVQVRLGEDGELLVRGPIVMKGYLGRPELTAELIDDEGWLYTGDVARIDDEGYIYIIDRKKEIIVNSSGKNISPAGIEGH
LKAASPLIGQAVVIGEARPFLTALIVLDADAAGQYAASRALPADASSLAADEGVVAALSAAVTEANTHVSQVEHVRKFAV
LPQFWEPGSELLTHTMKLRRRPIGARYADVIEALYRLPRDESVLRIADAASAS

Sequences:

>Translated_773_residues
MRVRAHRQISAPVDVVWDVVTDHEGMSTWFPGVAVALERPGVQGGIGAVRIVRMTGLSIREQVTDIEPARRLAYRCISGH
PLRDYRGEIFLAPSGTGTSLTWVLDTSTRFRLVAWLLVNQARLFAWSLARAAERSSALIRSADTDRTKEPAVQHVQSTAS
TQQTPGADSSPGPASLAEAFQRNASRDPQALALSTPDGSATLTWGQYAEQVRDIAAALHAHGVRRGDSVALMMLNRPEFY
PIDTAAIHLGAIPFSIYNTSSAEQIRWLFASAKPSMVFCDSSHAAAVLEAVDGGTAVKAVVCVDGDVEGATTSVEFRGVR
SDDFDFESTWRSVTPDDVLTLIYTSGTTGEPKGVQITHGNMLAQLAATNTFLEAGPGDRVISFLPSAHIADRWAAHYLQL
VCGTTVYPLVDRTQLLPTMLRVRPTLFGAVPQVWQKIRAGVLAMIDAEADEERQAGIQQTLAVGARYARSRSDGTLTAEL
ESLFATADTQVLSHLRSRLGLDQARIVMSGAAAVPVEIVEFFNSIGVPLIDGWGMSELSCMGAFMPNHAPRLGSVGMALP
GVQVRLGEDGELLVRGPIVMKGYLGRPELTAELIDDEGWLYTGDVARIDDEGYIYIIDRKKEIIVNSSGKNISPAGIEGH
LKAASPLIGQAVVIGEARPFLTALIVLDADAAGQYAASRALPADASSLAADEGVVAALSAAVTEANTHVSQVEHVRKFAV
LPQFWEPGSELLTHTMKLRRRPIGARYADVIEALYRLPRDESVLRIADAASAS
>Mature_773_residues
MRVRAHRQISAPVDVVWDVVTDHEGMSTWFPGVAVALERPGVQGGIGAVRIVRMTGLSIREQVTDIEPARRLAYRCISGH
PLRDYRGEIFLAPSGTGTSLTWVLDTSTRFRLVAWLLVNQARLFAWSLARAAERSSALIRSADTDRTKEPAVQHVQSTAS
TQQTPGADSSPGPASLAEAFQRNASRDPQALALSTPDGSATLTWGQYAEQVRDIAAALHAHGVRRGDSVALMMLNRPEFY
PIDTAAIHLGAIPFSIYNTSSAEQIRWLFASAKPSMVFCDSSHAAAVLEAVDGGTAVKAVVCVDGDVEGATTSVEFRGVR
SDDFDFESTWRSVTPDDVLTLIYTSGTTGEPKGVQITHGNMLAQLAATNTFLEAGPGDRVISFLPSAHIADRWAAHYLQL
VCGTTVYPLVDRTQLLPTMLRVRPTLFGAVPQVWQKIRAGVLAMIDAEADEERQAGIQQTLAVGARYARSRSDGTLTAEL
ESLFATADTQVLSHLRSRLGLDQARIVMSGAAAVPVEIVEFFNSIGVPLIDGWGMSELSCMGAFMPNHAPRLGSVGMALP
GVQVRLGEDGELLVRGPIVMKGYLGRPELTAELIDDEGWLYTGDVARIDDEGYIYIIDRKKEIIVNSSGKNISPAGIEGH
LKAASPLIGQAVVIGEARPFLTALIVLDADAAGQYAASRALPADASSLAADEGVVAALSAAVTEANTHVSQVEHVRKFAV
LPQFWEPGSELLTHTMKLRRRPIGARYADVIEALYRLPRDESVLRIADAASAS

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI83745141, Length=636, Percent_Identity=26.5723270440252, Blast_Score=214, Evalue=3e-55,
Organism=Homo sapiens, GI27477105, Length=609, Percent_Identity=28.0788177339901, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI40807491, Length=617, Percent_Identity=26.742301458671, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI42794760, Length=623, Percent_Identity=26.9662921348315, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI42794758, Length=623, Percent_Identity=26.9662921348315, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI42794756, Length=623, Percent_Identity=26.9662921348315, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI57165412, Length=588, Percent_Identity=24.6598639455782, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI57165410, Length=588, Percent_Identity=24.4897959183673, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI12669909, Length=710, Percent_Identity=22.5352112676056, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI4758332, Length=659, Percent_Identity=22.6100151745068, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI42794754, Length=459, Percent_Identity=25.0544662309368, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI42794752, Length=459, Percent_Identity=25.0544662309368, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI156151445, Length=164, Percent_Identity=32.3170731707317, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI1788107, Length=510, Percent_Identity=26.078431372549, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI145693145, Length=166, Percent_Identity=33.7349397590361, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1789201, Length=370, Percent_Identity=25.4054054054054, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI221142682, Length=151, Percent_Identity=31.1258278145695, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17510401, Length=596, Percent_Identity=26.1744966442953, Blast_Score=183, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17556552, Length=592, Percent_Identity=25.3378378378378, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI25147511, Length=597, Percent_Identity=25.6281407035176, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17564090, Length=590, Percent_Identity=27.2881355932203, Blast_Score=170, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17541856, Length=599, Percent_Identity=25.2086811352254, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17553312, Length=463, Percent_Identity=28.0777537796976, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI193204819, Length=627, Percent_Identity=22.8070175438596, Blast_Score=115, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17558820, Length=474, Percent_Identity=24.4725738396624, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71996755, Length=492, Percent_Identity=23.1707317073171, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32563687, Length=164, Percent_Identity=29.2682926829268, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559526, Length=178, Percent_Identity=34.2696629213483, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71985884, Length=369, Percent_Identity=23.3062330623306, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17531443, Length=123, Percent_Identity=34.1463414634146, Blast_Score=79, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320852, Length=581, Percent_Identity=23.7521514629948, Blast_Score=148, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6323903, Length=448, Percent_Identity=26.1160714285714, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6322182, Length=447, Percent_Identity=24.6085011185682, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324893, Length=449, Percent_Identity=24.9443207126949, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI19921316, Length=655, Percent_Identity=28.2442748091603, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI17933690, Length=634, Percent_Identity=26.813880126183, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24666501, Length=587, Percent_Identity=26.0647359454855, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24666497, Length=587, Percent_Identity=26.0647359454855, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI281366413, Length=587, Percent_Identity=26.0647359454855, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI62471681, Length=517, Percent_Identity=23.7911025145068, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI62471687, Length=517, Percent_Identity=23.7911025145068, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24586634, Length=517, Percent_Identity=23.7911025145068, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI22026970, Length=517, Percent_Identity=23.7911025145068, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI62471689, Length=520, Percent_Identity=23.8461538461538, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI62471679, Length=517, Percent_Identity=23.7911025145068, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI62471683, Length=517, Percent_Identity=23.7911025145068, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI62471685, Length=517, Percent_Identity=23.7911025145068, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24586636, Length=517, Percent_Identity=23.7911025145068, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21356947, Length=138, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859661, Length=171, Percent_Identity=34.5029239766082, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355181, Length=172, Percent_Identity=33.1395348837209, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648260, Length=134, Percent_Identity=32.8358208955224, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076582, Length=175, Percent_Identity=30.8571428571429, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24653035, Length=118, Percent_Identity=33.8983050847458, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: 6.2.1.3 [C]

Molecular weight: Translated: 83111; Mature: 83111

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRAHRQISAPVDVVWDVVTDHEGMSTWFPGVAVALERPGVQGGIGAVRIVRMTGLSIR
CCCCCCCCCCCCHHHHHHHHCCCCCCCHHCCCEEEEEECCCCCCCCCCEEEEEECCCHHH
EQVTDIEPARRLAYRCISGHPLRDYRGEIFLAPSGTGTSLTWVLDTSTRFRLVAWLLVNQ
HHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHH
ARLFAWSLARAAERSSALIRSADTDRTKEPAVQHVQSTASTQQTPGADSSPGPASLAEAF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
QRNASRDPQALALSTPDGSATLTWGQYAEQVRDIAAALHAHGVRRGDSVALMMLNRPEFY
HHCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
PIDTAAIHLGAIPFSIYNTSSAEQIRWLFASAKPSMVFCDSSHAAAVLEAVDGGTAVKAV
CCCHHHEEECCCEEEEECCCCHHHHHHEEECCCCCEEEECCCCHHHHHHHCCCCCEEEEE
VCVDGDVEGATTSVEFRGVRSDDFDFESTWRSVTPDDVLTLIYTSGTTGEPKGVQITHGN
EEECCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEECCH
MLAQLAATNTFLEAGPGDRVISFLPSAHIADRWAAHYLQLVCGTTVYPLVDRTQLLPTML
HHHHHHHHHHHEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RVRPTLFGAVPQVWQKIRAGVLAMIDAEADEERQAGIQQTLAVGARYARSRSDGTLTAEL
HHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
ESLFATADTQVLSHLRSRLGLDQARIVMSGAAAVPVEIVEFFNSIGVPLIDGWGMSELSC
HHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCHHHHHHHHHHCCCCEECCCCCHHHHH
MGAFMPNHAPRLGSVGMALPGVQVRLGEDGELLVRGPIVMKGYLGRPELTAELIDDEGWL
HHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCEEEECCCCCCCCCCEEECCCCCE
YTGDVARIDDEGYIYIIDRKKEIIVNSSGKNISPAGIEGHLKAASPLIGQAVVIGEARPF
EECCEEEECCCCEEEEEECCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCHH
LTALIVLDADAAGQYAASRALPADASSLAADEGVVAALSAAVTEANTHVSQVEHVRKFAV
EEEEEEEECCCCCCHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPQFWEPGSELLTHTMKLRRRPIGARYADVIEALYRLPRDESVLRIADAASAS
CCHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRVRAHRQISAPVDVVWDVVTDHEGMSTWFPGVAVALERPGVQGGIGAVRIVRMTGLSIR
CCCCCCCCCCCCHHHHHHHHCCCCCCCHHCCCEEEEEECCCCCCCCCCEEEEEECCCHHH
EQVTDIEPARRLAYRCISGHPLRDYRGEIFLAPSGTGTSLTWVLDTSTRFRLVAWLLVNQ
HHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHH
ARLFAWSLARAAERSSALIRSADTDRTKEPAVQHVQSTASTQQTPGADSSPGPASLAEAF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
QRNASRDPQALALSTPDGSATLTWGQYAEQVRDIAAALHAHGVRRGDSVALMMLNRPEFY
HHCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
PIDTAAIHLGAIPFSIYNTSSAEQIRWLFASAKPSMVFCDSSHAAAVLEAVDGGTAVKAV
CCCHHHEEECCCEEEEECCCCHHHHHHEEECCCCCEEEECCCCHHHHHHHCCCCCEEEEE
VCVDGDVEGATTSVEFRGVRSDDFDFESTWRSVTPDDVLTLIYTSGTTGEPKGVQITHGN
EEECCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEECCH
MLAQLAATNTFLEAGPGDRVISFLPSAHIADRWAAHYLQLVCGTTVYPLVDRTQLLPTML
HHHHHHHHHHHEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RVRPTLFGAVPQVWQKIRAGVLAMIDAEADEERQAGIQQTLAVGARYARSRSDGTLTAEL
HHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
ESLFATADTQVLSHLRSRLGLDQARIVMSGAAAVPVEIVEFFNSIGVPLIDGWGMSELSC
HHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCHHHHHHHHHHCCCCEECCCCCHHHHH
MGAFMPNHAPRLGSVGMALPGVQVRLGEDGELLVRGPIVMKGYLGRPELTAELIDDEGWL
HHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCEEEECCCCCCCCCCEEECCCCCE
YTGDVARIDDEGYIYIIDRKKEIIVNSSGKNISPAGIEGHLKAASPLIGQAVVIGEARPF
EECCEEEECCCCEEEEEECCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCHH
LTALIVLDADAAGQYAASRALPADASSLAADEGVVAALSAAVTEANTHVSQVEHVRKFAV
EEEEEEEECCCCCCHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPQFWEPGSELLTHTMKLRRRPIGARYADVIEALYRLPRDESVLRIADAASAS
CCHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Salts [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0408 {octanoate}} 0.0125 {octanoate}} 0.0059 {octanoate}} 0.00072 {octanoate}} 0.0013 {undecanoate}} 0.0022 {pentadecanoate}} 0.053 {CoA}} 0.035 {CoA}} 0.034 {CoA}} 0.0034 {tridecanoate}} 0.002 {laurate}} 0.0019 {laurate}} 0.0

Substrates: ATP; a long-chain carboxylic acid; CoA [C]

Specific reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate +an acyl-CoA [C]

General reaction: Acid-thiol ligation; Phosphorylation [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]