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The map label for this gene is mmgC [H]

Identifier: 158314760

GI number: 158314760

Start: 3461035

End: 3462204

Strand: Direct

Name: mmgC [H]

Synonym: Franean1_2942

Alternate gene names: 158314760

Gene position: 3461035-3462204 (Clockwise)

Preceding gene: 158314759

Following gene: 158314761

Centisome position: 38.53

GC content: 65.64

Gene sequence:

>1170_bases
TTGACTACCGCCACCGTCCCCGTCGCGCGTCGTCCGTCCTGGATGGACGACGAGACCGCGGACCTCGCCGCGCTCGCCCG
CGCCTTCTTCGAGAAGGAGGTCGTCCCCGCGCTCCCCGAAGCGACCAAGCGGGGTTTTCCCGACAGATCCCTTTACCGTC
GTGCAGGCGAGCTCGGCCTGCTGGGAATGGGTCTGCCCGAGGAGTACGGGGGTGGTGGGGGGACCTTCGCCCACGAGGCG
GTCCTGTTCACCGAGCAGGTGATGGCCGGAGACAACAGCCTGCACCTCGGAGTGCATGCGGGCATCGTCCCGCACTACAT
CGCCGCCTACGCCTCCGAGGAGAACAAGTCCTTCTGGCTGCCCAAGCTCATCAGTGGTGAGTGGATCGGCGCCATCGCCA
TGACCGAGCCGTCCACGGGCTCGGATCTCCAGGCCATCAAGGCGCGTGCGGTGCAAGACGGCGACGACTACATCATCATG
GGCTCGAAGACCTTCATCTCGAACGGGCACAATGCCGATCTGGTCATCATCGCGGTGAAGACGGACCCGTCCCTCGGCGC
CCGAGGGGTATCCCTCGTCGTGGCCGAGGTCGGTGACGACCCCCCTGGCTTCCAGCGTGGTCGCATCATCGAGAAGATCG
GGCAGAAGGGTCAGGACACCACGGAGTTGTTCTTCGACGGCCTGCGCGTTCCCACCAGTCACCTGCTCGGCGGCGTCGAG
GGCCGGGGCTTCGCCCAGCTCATGGAGCAGCTGCCGCAGGAACGGCTCATCTGCGCCGTGGCCGCGGTTGCCGCGATCGA
ACGGGCTGTCGCACTGACGATCGACTACACCAAGACGCGCACCGCCTTCGGTAAGCCGCTGTTCGACATGCAGCACACGC
GGTTCGAACTCGCCGAGTGCGCGACGATCGCCCGGGTCAGCCGGAGTTTTCTCGACGACTGCATCGAGCAGCATCTGAAG
GGCGCGCTCGACGTGACCACCGCCGCGATGGCGAAGTACTACCTCACCGACCAGCAGTGCGCGGTCATCGACCGCTGCCT
GCAGCTGTTCGGCGGGTACGGCTACACCACCGAATACCCCATCGGCCGGATGTACACCGACGCTCGTGTCCAGCGGATCT
ACGCCGGAGCGAACGAAGTCATGAAGGAACTCATTAGCCGCTCGCTGTGA

Upstream 100 bases:

>100_bases
CCTCCTAGCCGGCTTTTCCCGGAGTCGAACCGGGCCGCCGGCCACCACACACAGCGACGGCTTCGTCGACCAGGGCGCAG
CGCCGATACAAGGAGAGCAA

Downstream 100 bases:

>100_bases
GTGGCCAGGCCGGTAATGGAAGGAACCCCGCACGTGAGCGCTGAAGCCTTCGTCTACGATGCCGTTCGCACGCCCCGTGG
GCGTGGCCGGAAGGGATCAC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTTATVPVARRPSWMDDETADLAALARAFFEKEVVPALPEATKRGFPDRSLYRRAGELGLLGMGLPEEYGGGGGTFAHEA
VLFTEQVMAGDNSLHLGVHAGIVPHYIAAYASEENKSFWLPKLISGEWIGAIAMTEPSTGSDLQAIKARAVQDGDDYIIM
GSKTFISNGHNADLVIIAVKTDPSLGARGVSLVVAEVGDDPPGFQRGRIIEKIGQKGQDTTELFFDGLRVPTSHLLGGVE
GRGFAQLMEQLPQERLICAVAAVAAIERAVALTIDYTKTRTAFGKPLFDMQHTRFELAECATIARVSRSFLDDCIEQHLK
GALDVTTAAMAKYYLTDQQCAVIDRCLQLFGGYGYTTEYPIGRMYTDARVQRIYAGANEVMKELISRSL

Sequences:

>Translated_389_residues
MTTATVPVARRPSWMDDETADLAALARAFFEKEVVPALPEATKRGFPDRSLYRRAGELGLLGMGLPEEYGGGGGTFAHEA
VLFTEQVMAGDNSLHLGVHAGIVPHYIAAYASEENKSFWLPKLISGEWIGAIAMTEPSTGSDLQAIKARAVQDGDDYIIM
GSKTFISNGHNADLVIIAVKTDPSLGARGVSLVVAEVGDDPPGFQRGRIIEKIGQKGQDTTELFFDGLRVPTSHLLGGVE
GRGFAQLMEQLPQERLICAVAAVAAIERAVALTIDYTKTRTAFGKPLFDMQHTRFELAECATIARVSRSFLDDCIEQHLK
GALDVTTAAMAKYYLTDQQCAVIDRCLQLFGGYGYTTEYPIGRMYTDARVQRIYAGANEVMKELISRSL
>Mature_388_residues
TTATVPVARRPSWMDDETADLAALARAFFEKEVVPALPEATKRGFPDRSLYRRAGELGLLGMGLPEEYGGGGGTFAHEAV
LFTEQVMAGDNSLHLGVHAGIVPHYIAAYASEENKSFWLPKLISGEWIGAIAMTEPSTGSDLQAIKARAVQDGDDYIIMG
SKTFISNGHNADLVIIAVKTDPSLGARGVSLVVAEVGDDPPGFQRGRIIEKIGQKGQDTTELFFDGLRVPTSHLLGGVEG
RGFAQLMEQLPQERLICAVAAVAAIERAVALTIDYTKTRTAFGKPLFDMQHTRFELAECATIARVSRSFLDDCIEQHLKG
ALDVTTAAMAKYYLTDQQCAVIDRCLQLFGGYGYTTEYPIGRMYTDARVQRIYAGANEVMKELISRSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=366, Percent_Identity=45.6284153005465, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI226958412, Length=398, Percent_Identity=31.9095477386935, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI226958414, Length=351, Percent_Identity=33.6182336182336, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=31.7460317460317, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=31.0526315789474, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=28.5333333333333, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=30.952380952381, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=30.952380952381, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI4557235, Length=387, Percent_Identity=31.5245478036176, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI21361497, Length=353, Percent_Identity=32.0113314447592, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI76496475, Length=387, Percent_Identity=31.5245478036176, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI211971008, Length=408, Percent_Identity=27.6960784313726, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI48976061, Length=408, Percent_Identity=27.6960784313726, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4503943, Length=374, Percent_Identity=26.2032085561497, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI7669494, Length=348, Percent_Identity=27.2988505747126, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38505218, Length=286, Percent_Identity=28.3216783216783, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI87081958, Length=348, Percent_Identity=27.5862068965517, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786223, Length=350, Percent_Identity=23.4285714285714, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082384, Length=265, Percent_Identity=25.2830188679245, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=34.6560846560847, Blast_Score=224, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI17551932, Length=370, Percent_Identity=33.2432432432432, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17533517, Length=384, Percent_Identity=32.5520833333333, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17505929, Length=387, Percent_Identity=31.266149870801, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17508101, Length=375, Percent_Identity=28, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17569725, Length=368, Percent_Identity=30.7065217391304, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17534899, Length=378, Percent_Identity=29.3650793650794, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17570075, Length=376, Percent_Identity=28.1914893617021, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=28.5326086956522, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71985184, Length=393, Percent_Identity=29.7709923664122, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71990804, Length=285, Percent_Identity=31.5789473684211, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI71982178, Length=296, Percent_Identity=28.0405405405405, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32563615, Length=256, Percent_Identity=30.078125, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71985192, Length=325, Percent_Identity=29.8461538461538, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=387, Percent_Identity=26.0981912144703, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=297, Percent_Identity=30.3030303030303, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17531909, Length=238, Percent_Identity=26.890756302521, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI86563383, Length=284, Percent_Identity=28.5211267605634, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI86563381, Length=284, Percent_Identity=28.5211267605634, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355753, Length=393, Percent_Identity=32.5699745547074, Blast_Score=197, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24646207, Length=383, Percent_Identity=30.5483028720627, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21356377, Length=359, Percent_Identity=29.2479108635098, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=28.2321899736148, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24666513, Length=346, Percent_Identity=29.4797687861272, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281363737, Length=340, Percent_Identity=29.1176470588235, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI19920834, Length=404, Percent_Identity=25.2475247524752, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42291; Mature: 42160

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTATVPVARRPSWMDDETADLAALARAFFEKEVVPALPEATKRGFPDRSLYRRAGELGL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHCCCCCE
LGMGLPEEYGGGGGTFAHEAVLFTEQVMAGDNSLHLGVHAGIVPHYIAAYASEENKSFWL
EECCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCCCCEEC
PKLISGEWIGAIAMTEPSTGSDLQAIKARAVQDGDDYIIMGSKTFISNGHNADLVIIAVK
CHHHCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHEECCCCCCCEEEEEEE
TDPSLGARGVSLVVAEVGDDPPGFQRGRIIEKIGQKGQDTTELFFDGLRVPTSHLLGGVE
CCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHHCCCCCCHHHHHCCCC
GRGFAQLMEQLPQERLICAVAAVAAIERAVALTIDYTKTRTAFGKPLFDMQHTRFELAEC
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHCCCCHHHHHHHHHHHHH
ATIARVSRSFLDDCIEQHLKGALDVTTAAMAKYYLTDQQCAVIDRCLQLFGGYGYTTEYP
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
IGRMYTDARVQRIYAGANEVMKELISRSL
CCHHHHHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure 
TTATVPVARRPSWMDDETADLAALARAFFEKEVVPALPEATKRGFPDRSLYRRAGELGL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHCCCCCE
LGMGLPEEYGGGGGTFAHEAVLFTEQVMAGDNSLHLGVHAGIVPHYIAAYASEENKSFWL
EECCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCCCCEEC
PKLISGEWIGAIAMTEPSTGSDLQAIKARAVQDGDDYIIMGSKTFISNGHNADLVIIAVK
CHHHCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHEECCCCCCCEEEEEEE
TDPSLGARGVSLVVAEVGDDPPGFQRGRIIEKIGQKGQDTTELFFDGLRVPTSHLLGGVE
CCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHHCCCCCCHHHHHCCCC
GRGFAQLMEQLPQERLICAVAAVAAIERAVALTIDYTKTRTAFGKPLFDMQHTRFELAEC
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHCCCCHHHHHHHHHHHHH
ATIARVSRSFLDDCIEQHLKGALDVTTAAMAKYYLTDQQCAVIDRCLQLFGGYGYTTEYP
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
IGRMYTDARVQRIYAGANEVMKELISRSL
CCHHHHHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]