Click here to switch to the map view.

The map label for this gene is echA8 [H]

Identifier: 158314533

GI number: 158314533

Start: 3205256

End: 3206050

Strand: Direct

Name: echA8 [H]

Synonym: Franean1_2709

Alternate gene names: 158314533

Gene position: 3205256-3206050 (Clockwise)

Preceding gene: 158314532

Following gene: 158314534

Centisome position: 35.69

GC content: 68.68

Gene sequence:

>795_bases
GTGAATGTTCTCTACGAGGTCGCCGGCAGGGTCGCGACCATCACTCTGAACCGGCCCGAGGCCGCCAACGCCCAGAGCAT
GGAGCTGCTCGACGAACTCGACGCAGCCTGGACGCGAGCGGCGGCGGACGACGCAGTGGCCGTCGTCGTCCTGCGCGGTG
CCGGCCGGCACTTCTCCGCCGGGCATGACCTGAAGGGTTCCGGGGCGAAGCACGCCAAGCCGACTCTCGAGACGATCTAC
CGGTTCGAGGCGAGGCGCTATCTGGAGTACTCGTTGCGCTGGCGGAACATACCGAAGCCGTCGATCGCGGCGGTGCAGGG
CCGTTGCATCGCCGGCGGGCTGCTGCTGTGCTGGCCGTGCGATCTGATCATCGCCGCCGAGGACGCGCTGTTCTCCGACC
CGGTGGTGGCGATGGGGATCGGTGGTGTCGAGTACCACGGGCACACCTGGGAGCTGGGGCCGCGCAAGGCCAAGGAGATC
CTGTTCACCGGCCGTCCGCTGACCGCGGCGGAGGCGGAACGGGTCGGCATGGTGAACAGGGTGGTGCCGCGCGAGGAGCT
GGAGGCCACGACGCGGGCGCTCGCCGAGCAGATCGCCGCGATGCCGGCCTTCGGGCTGCGCCAGGCCAAGCGTGCGGTGA
ACCAGACCCTGGACGTGCAGGGTTTCTACGCGGCGATCCAGTCGGTGTTCGACGTCCACCAGACCGGGCATGGCAACGCG
CTCAGCGTCAGCGGTCTCCCGATCCTGGTGGACCTGGACCAGATGAAGGCGAAGGTCAAGACGGAGCTGCTCTAG

Upstream 100 bases:

>100_bases
GCGGTCGAGGGCCACCTGCCGGGCCCGATACACCAGGGCCCGGACCGGCACCGTCTCCGACCTCGCGTCCCCGCATCCCT
CTGCCGACTGAGGAGTCGCC

Downstream 100 bases:

>100_bases
CAGGCGACTGCCGTAAATATCGACATCGAGCTCGATATCGACTATCGTCGCGGCGGGTACGTGGCGGGTAAGGAAGGATC
GCGAACATGCGGGAGAGCGA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MNVLYEVAGRVATITLNRPEAANAQSMELLDELDAAWTRAAADDAVAVVVLRGAGRHFSAGHDLKGSGAKHAKPTLETIY
RFEARRYLEYSLRWRNIPKPSIAAVQGRCIAGGLLLCWPCDLIIAAEDALFSDPVVAMGIGGVEYHGHTWELGPRKAKEI
LFTGRPLTAAEAERVGMVNRVVPREELEATTRALAEQIAAMPAFGLRQAKRAVNQTLDVQGFYAAIQSVFDVHQTGHGNA
LSVSGLPILVDLDQMKAKVKTELL

Sequences:

>Translated_264_residues
MNVLYEVAGRVATITLNRPEAANAQSMELLDELDAAWTRAAADDAVAVVVLRGAGRHFSAGHDLKGSGAKHAKPTLETIY
RFEARRYLEYSLRWRNIPKPSIAAVQGRCIAGGLLLCWPCDLIIAAEDALFSDPVVAMGIGGVEYHGHTWELGPRKAKEI
LFTGRPLTAAEAERVGMVNRVVPREELEATTRALAEQIAAMPAFGLRQAKRAVNQTLDVQGFYAAIQSVFDVHQTGHGNA
LSVSGLPILVDLDQMKAKVKTELL
>Mature_264_residues
MNVLYEVAGRVATITLNRPEAANAQSMELLDELDAAWTRAAADDAVAVVVLRGAGRHFSAGHDLKGSGAKHAKPTLETIY
RFEARRYLEYSLRWRNIPKPSIAAVQGRCIAGGLLLCWPCDLIIAAEDALFSDPVVAMGIGGVEYHGHTWELGPRKAKEI
LFTGRPLTAAEAERVGMVNRVVPREELEATTRALAEQIAAMPAFGLRQAKRAVNQTLDVQGFYAAIQSVFDVHQTGHGNA
LSVSGLPILVDLDQMKAKVKTELL

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=213, Percent_Identity=32.3943661971831, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI31542718, Length=226, Percent_Identity=29.2035398230088, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI70995211, Length=189, Percent_Identity=31.7460317460317, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI45643119, Length=208, Percent_Identity=28.3653846153846, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI260275230, Length=208, Percent_Identity=28.3653846153846, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI260274832, Length=208, Percent_Identity=28.3653846153846, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI1788597, Length=213, Percent_Identity=33.8028169014084, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787659, Length=218, Percent_Identity=33.4862385321101, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787660, Length=226, Percent_Identity=34.070796460177, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI221142681, Length=228, Percent_Identity=32.8947368421053, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082183, Length=202, Percent_Identity=32.6732673267327, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25145438, Length=219, Percent_Identity=35.6164383561644, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17554946, Length=214, Percent_Identity=31.7757009345794, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17535521, Length=210, Percent_Identity=25.7142857142857, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=233, Percent_Identity=27.4678111587983, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17549921, Length=217, Percent_Identity=25.3456221198157, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536985, Length=231, Percent_Identity=25.5411255411255, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=240, Percent_Identity=28.3333333333333, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17540306, Length=196, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=220, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540714, Length=237, Percent_Identity=26.5822784810127, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129971, Length=216, Percent_Identity=33.7962962962963, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24653477, Length=216, Percent_Identity=33.7962962962963, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357171, Length=236, Percent_Identity=29.2372881355932, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24650670, Length=230, Percent_Identity=31.304347826087, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24654903, Length=214, Percent_Identity=28.0373831775701, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24653139, Length=218, Percent_Identity=33.4862385321101, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19922422, Length=199, Percent_Identity=28.1407035175879, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920382, Length=222, Percent_Identity=28.3783783783784, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28650; Mature: 28650

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLYEVAGRVATITLNRPEAANAQSMELLDELDAAWTRAAADDAVAVVVLRGAGRHFSA
CCHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
GHDLKGSGAKHAKPTLETIYRFEARRYLEYSLRWRNIPKPSIAAVQGRCIAGGLLLCWPC
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHCCCEEEEECC
DLIIAAEDALFSDPVVAMGIGGVEYHGHTWELGPRKAKEILFTGRPLTAAEAERVGMVNR
CEEEEECCHHCCCCCCEEECCCEEECCCEECCCCHHHHHHEECCCCCCHHHHHHHHHHHH
VVPREELEATTRALAEQIAAMPAFGLRQAKRAVNQTLDVQGFYAAIQSVFDVHQTGHGNA
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCE
LSVSGLPILVDLDQMKAKVKTELL
EEECCCEEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MNVLYEVAGRVATITLNRPEAANAQSMELLDELDAAWTRAAADDAVAVVVLRGAGRHFSA
CCHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
GHDLKGSGAKHAKPTLETIYRFEARRYLEYSLRWRNIPKPSIAAVQGRCIAGGLLLCWPC
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHCCCEEEEECC
DLIIAAEDALFSDPVVAMGIGGVEYHGHTWELGPRKAKEILFTGRPLTAAEAERVGMVNR
CEEEEECCHHCCCCCCEEECCCEEECCCEECCCCHHHHHHEECCCCCCHHHHHHHHHHHH
VVPREELEATTRALAEQIAAMPAFGLRQAKRAVNQTLDVQGFYAAIQSVFDVHQTGHGNA
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCE
LSVSGLPILVDLDQMKAKVKTELL
EEECCCEEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]