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The map label for this gene is mmgC [H]

Identifier: 158314534

GI number: 158314534

Start: 3206137

End: 3207324

Strand: Direct

Name: mmgC [H]

Synonym: Franean1_2710

Alternate gene names: 158314534

Gene position: 3206137-3207324 (Clockwise)

Preceding gene: 158314533

Following gene: 158314537

Centisome position: 35.69

GC content: 69.44

Gene sequence:

>1188_bases
ATGCGGGAGAGCGACTTCGTCGAGGTGCTCGCGGCTGTCCGTGCTTTCGTGCGGGAACGGGTGGTGCCCGCCGAGACGGA
GATCGAGGAGAAGGACGCCATACCGAACGGCCTGAGGGTCGAGGCCGCGCGGATGGGACTGTTCGGCTTCGCCATCCCGG
AGACGTACGGCGGCCTGGGCCTGTCGATGAGCGAGGAGGTCCGCCTCGTCGGCGAGCTCGGATACACGACGCCGTCGTTC
CGGTCGATGTTCGGGACCAACAACGGCATCGCCGGGCACGTCCTCCTGGAAGGCGCCAGTGCGGAACAGAAGGAGACGTA
CCTCCCCAAGATCGCTTCGGGTGAGTGGACGGCGTCCTTCGCACTCACGGAGGAAGGCGCGGGTTCCGACCCGGCCGGGC
TGGCCACCTCGGCGGTCCGCAAGGGCGACGACTGGATCATCAACGGGTCCAAGCGGTACATCACCAACGCTCCGATCGCC
GACGTCTTCATGGTCTTCGCCCGAACCGACCCGGCGGCCACCGGCGGCGACGGCATCAGTGTCTTCATGGTGGAGCGCGA
CACGCCGGGCGTACGCGTGGCCCCCAAGGACGCGAAGATGGGCCAGGCGGGTTCACTGACGGCGGACGTCTACTTCGACG
ACGTCCGCGTCGACCCGCAGACCCTGGTCGGCGGTACTGCCGGCGAGGGGCGTGGCTACAACACCGCGATGCGCTGCCTG
GCGCACGGACGCATCCACATCGCCGCGCTGTGCGTCGGCCTCGCGCAACGGCTGCTGGACGAGTCGGTCGCCTATGCCGC
CACCCGGTCGCAGGGCGGCCGGACCATCGGTACCTACCAGCTCATTCAGGGGCTGCTGGCGGACTCGGCCACCGATCTGT
ACGCGGCCCGGGCCCTGGTGAAGGAGACGGCCGCGGCGTTCGACGACGGCAGCGACACCAGAATCGGTCCGTCCTGCGCG
AAGTACTTCGCGTCGGAGGCCGTCGGCCGCATCGCGGACCGTGCCGTCCAGATCCACGGCGGCGCGGGCTACATGCGCGG
GGTTCCGGTCGAGCGGTTCTACCGGGATGTGCGCCTGTTCCGGATCTACGAGGGGACCAGCCAGATCCAGCAGCTCGTCA
TCGCCCGCCAGCTGCTGCGCGCGGCGGACGGCGGGAAGAACCAGGGCGGGAACCGCGCCCAGGTGTGA

Upstream 100 bases:

>100_bases
CGGAGCTGCTCTAGCAGGCGACTGCCGTAAATATCGACATCGAGCTCGATATCGACTATCGTCGCGGCGGGTACGTGGCG
GGTAAGGAAGGATCGCGAAC

Downstream 100 bases:

>100_bases
CTGTGCGGGGCGGCGTACCGCACCAGCGGCGCGGCGGGGGCTACGGCCGGCTGACAACCAGGCCCGCCCGGTGTCCTCGT
GGGGACCGGGCGGGGCCAGG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MRESDFVEVLAAVRAFVRERVVPAETEIEEKDAIPNGLRVEAARMGLFGFAIPETYGGLGLSMSEEVRLVGELGYTTPSF
RSMFGTNNGIAGHVLLEGASAEQKETYLPKIASGEWTASFALTEEGAGSDPAGLATSAVRKGDDWIINGSKRYITNAPIA
DVFMVFARTDPAATGGDGISVFMVERDTPGVRVAPKDAKMGQAGSLTADVYFDDVRVDPQTLVGGTAGEGRGYNTAMRCL
AHGRIHIAALCVGLAQRLLDESVAYAATRSQGGRTIGTYQLIQGLLADSATDLYAARALVKETAAAFDDGSDTRIGPSCA
KYFASEAVGRIADRAVQIHGGAGYMRGVPVERFYRDVRLFRIYEGTSQIQQLVIARQLLRAADGGKNQGGNRAQV

Sequences:

>Translated_395_residues
MRESDFVEVLAAVRAFVRERVVPAETEIEEKDAIPNGLRVEAARMGLFGFAIPETYGGLGLSMSEEVRLVGELGYTTPSF
RSMFGTNNGIAGHVLLEGASAEQKETYLPKIASGEWTASFALTEEGAGSDPAGLATSAVRKGDDWIINGSKRYITNAPIA
DVFMVFARTDPAATGGDGISVFMVERDTPGVRVAPKDAKMGQAGSLTADVYFDDVRVDPQTLVGGTAGEGRGYNTAMRCL
AHGRIHIAALCVGLAQRLLDESVAYAATRSQGGRTIGTYQLIQGLLADSATDLYAARALVKETAAAFDDGSDTRIGPSCA
KYFASEAVGRIADRAVQIHGGAGYMRGVPVERFYRDVRLFRIYEGTSQIQQLVIARQLLRAADGGKNQGGNRAQV
>Mature_395_residues
MRESDFVEVLAAVRAFVRERVVPAETEIEEKDAIPNGLRVEAARMGLFGFAIPETYGGLGLSMSEEVRLVGELGYTTPSF
RSMFGTNNGIAGHVLLEGASAEQKETYLPKIASGEWTASFALTEEGAGSDPAGLATSAVRKGDDWIINGSKRYITNAPIA
DVFMVFARTDPAATGGDGISVFMVERDTPGVRVAPKDAKMGQAGSLTADVYFDDVRVDPQTLVGGTAGEGRGYNTAMRCL
AHGRIHIAALCVGLAQRLLDESVAYAATRSQGGRTIGTYQLIQGLLADSATDLYAARALVKETAAAFDDGSDTRIGPSCA
KYFASEAVGRIADRAVQIHGGAGYMRGVPVERFYRDVRLFRIYEGTSQIQQLVIARQLLRAADGGKNQGGNRAQV

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=36.096256684492, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=36.096256684492, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI4557233, Length=373, Percent_Identity=37.2654155495979, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI4501859, Length=370, Percent_Identity=34.5945945945946, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI226958412, Length=365, Percent_Identity=34.5205479452055, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI4557235, Length=393, Percent_Identity=37.1501272264631, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI76496475, Length=393, Percent_Identity=37.1501272264631, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI21361497, Length=375, Percent_Identity=35.4666666666667, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI226958414, Length=370, Percent_Identity=34.8648648648649, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI4501857, Length=370, Percent_Identity=32.7027027027027, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI7656849, Length=366, Percent_Identity=33.879781420765, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI4503943, Length=378, Percent_Identity=26.7195767195767, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI38505218, Length=399, Percent_Identity=27.3182957393484, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI7669494, Length=292, Percent_Identity=28.4246575342466, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI48976061, Length=396, Percent_Identity=26.5151515151515, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI211971008, Length=396, Percent_Identity=26.5151515151515, Blast_Score=112, Evalue=8e-25,
Organism=Escherichia coli, GI1786223, Length=357, Percent_Identity=29.4117647058824, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87081958, Length=376, Percent_Identity=29.7872340425532, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI87081702, Length=320, Percent_Identity=27.5, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082384, Length=274, Percent_Identity=24.8175182481752, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=385, Percent_Identity=38.7012987012987, Blast_Score=238, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17508101, Length=368, Percent_Identity=37.5, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17569725, Length=375, Percent_Identity=37.8666666666667, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=37.7659574468085, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17506239, Length=364, Percent_Identity=37.0879120879121, Blast_Score=224, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=33.7837837837838, Blast_Score=214, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI71985184, Length=366, Percent_Identity=35.5191256830601, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=31.6622691292876, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=36.7857142857143, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=39.7435897435897, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71985192, Length=311, Percent_Identity=33.7620578778135, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71982178, Length=270, Percent_Identity=35.5555555555556, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17505929, Length=387, Percent_Identity=30.4909560723514, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17551932, Length=364, Percent_Identity=28.5714285714286, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17534353, Length=374, Percent_Identity=26.7379679144385, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562446, Length=360, Percent_Identity=28.3333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=297, Percent_Identity=26.5993265993266, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=297, Percent_Identity=26.5993265993266, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24660351, Length=382, Percent_Identity=36.6492146596859, Blast_Score=234, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24666513, Length=331, Percent_Identity=38.9728096676737, Blast_Score=218, Evalue=5e-57,
Organism=Drosophila melanogaster, GI281363737, Length=338, Percent_Identity=36.3905325443787, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24646207, Length=368, Percent_Identity=35.054347826087, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21355753, Length=368, Percent_Identity=34.2391304347826, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI21356377, Length=369, Percent_Identity=33.8753387533875, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI19920834, Length=379, Percent_Identity=28.7598944591029, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24652780, Length=343, Percent_Identity=24.198250728863, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 42075; Mature: 42075

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRESDFVEVLAAVRAFVRERVVPAETEIEEKDAIPNGLRVEAARMGLFGFAIPETYGGLG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCEEHHHHHCHHHEECCHHCCCCC
LSMSEEVRLVGELGYTTPSFRSMFGTNNGIAGHVLLEGASAEQKETYLPKIASGEWTASF
CCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCEEEEE
ALTEEGAGSDPAGLATSAVRKGDDWIINGSKRYITNAPIADVFMVFARTDPAATGGDGIS
EEECCCCCCCCCHHHHHHHHCCCCEEEECCCEEECCCCHHHHHHHHHCCCCCCCCCCCEE
VFMVERDTPGVRVAPKDAKMGQAGSLTADVYFDDVRVDPQTLVGGTAGEGRGYNTAMRCL
EEEEECCCCCCEECCCCCCCCCCCCEEEEEEEECEEECHHHHCCCCCCCCCCHHHHHHHH
AHGRIHIAALCVGLAQRLLDESVAYAATRSQGGRTIGTYQLIQGLLADSATDLYAARALV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHH
KETAAAFDDGSDTRIGPSCAKYFASEAVGRIADRAVQIHGGAGYMRGVPVERFYRDVRLF
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHEE
RIYEGTSQIQQLVIARQLLRAADGGKNQGGNRAQV
EEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRESDFVEVLAAVRAFVRERVVPAETEIEEKDAIPNGLRVEAARMGLFGFAIPETYGGLG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCEEHHHHHCHHHEECCHHCCCCC
LSMSEEVRLVGELGYTTPSFRSMFGTNNGIAGHVLLEGASAEQKETYLPKIASGEWTASF
CCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCEEEEE
ALTEEGAGSDPAGLATSAVRKGDDWIINGSKRYITNAPIADVFMVFARTDPAATGGDGIS
EEECCCCCCCCCHHHHHHHHCCCCEEEECCCEEECCCCHHHHHHHHHCCCCCCCCCCCEE
VFMVERDTPGVRVAPKDAKMGQAGSLTADVYFDDVRVDPQTLVGGTAGEGRGYNTAMRCL
EEEEECCCCCCEECCCCCCCCCCCCEEEEEEEECEEECHHHHCCCCCCCCCCHHHHHHHH
AHGRIHIAALCVGLAQRLLDESVAYAATRSQGGRTIGTYQLIQGLLADSATDLYAARALV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHH
KETAAAFDDGSDTRIGPSCAKYFASEAVGRIADRAVQIHGGAGYMRGVPVERFYRDVRLF
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHEE
RIYEGTSQIQQLVIARQLLRAADGGKNQGGNRAQV
EEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]