BacMap

Definition	Frankia sp. EAN1pec chromosome, complete genome.
Accession	NC_009921
Length	8,982,042

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The map label for this gene is fabG [H]

Identifier: 158314349

GI number: 158314349

Start: 2998951

End: 2999727

Strand: Direct

Name: fabG [H]

Synonym: Franean1_2519

Alternate gene names: 158314349

Gene position: 2998951-2999727 (Clockwise)

Preceding gene: 158314345

Following gene: 158314350

Centisome position: 33.39

GC content: 72.33

Gene sequence:

>777_bases
GTGGATCTCCGACTTTCAGGCCGACGGGCGATCGTCACTGGCGGTAGCCGCGGTATCGGGCGGGCGATCGCCCGAGCCCT
GCTCGCCGAGGGCGTGCAGGTCGTCATCGCCGCCCGTGACGCCGACGTGCTGAAATCGGCCGCGGCCGACCTGGCGACCG
CGACCGGCGGGACGGTGGTGCCGGTGATCGTCGACACCGGCAGCGACTCGTCCGTCCAGGAGCTGGTCGAGACCGCCGTC
GGCGAGCTCGGCGGCGTCGACATCCTGGTCAACAACGCGGCCAGGCCCGGTGGGGCCGGCGGACCCGGCGGCGCGCAGGC
CCTTTCCACCGCGGACGTCGCCGCCGACTTCAACGTGAAGGTGCTCGGCTACCTGCGTACCGCGCAGGCGGTCGCGCCGC
ACTTCATCGCACAGGGCTGGGGCCGGATCATCAACATCGGCGGGCTGGCGGCGCGCCAGGTCGGCCTCGCCTCCGGCTCC
ATCCGCAACGTCGGCGTCGCGGCCCTCACCAAGACCCTGGCCGACGAGCTCGGCGCGCACGGCGTCACGGTGAACGTGGT
GCATCCCGGACTGACCCTCACCGGTGACCATGGCGGCACGGTCGTTCTCTCCGACGAGCACATTCAGGCCGCCGCCGCCC
GCATCTCGATCGGGCGAGCCATCACCGCCGACGAGGTGGCCTCGGTCGTGGTCTTCCTCGCGTCCCCGCTCTCCGTCGCG
ATCACCGGCGAATCGATCGCCGCCGGCGGCGGCACCCAGGGCCCCATTCACTACTGA

Upstream 100 bases:

>100_bases
CACCTTCGGTAATCCGGCGGTAATCCGGCCGGCGGCGCGTCCCGAGCTTCACCGTGCCGCCGGAGTGGCCGGGTCACCGG
ACGAATGACAGGGAGCACGA

Downstream 100 bases:

>100_bases
CTGGCATCACCCAACCGAAGGGACACACCGTGACCACTGTCTTCGAAGCGCCCGTGCGATCGTCGTTGGCCGTCCAACCG
CTGCAACCGACCATCGGAGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MDLRLSGRRAIVTGGSRGIGRAIARALLAEGVQVVIAARDADVLKSAAADLATATGGTVVPVIVDTGSDSSVQELVETAV
GELGGVDILVNNAARPGGAGGPGGAQALSTADVAADFNVKVLGYLRTAQAVAPHFIAQGWGRIINIGGLAARQVGLASGS
IRNVGVAALTKTLADELGAHGVTVNVVHPGLTLTGDHGGTVVLSDEHIQAAAARISIGRAITADEVASVVVFLASPLSVA
ITGESIAAGGGTQGPIHY

Sequences:

>Translated_258_residues
MDLRLSGRRAIVTGGSRGIGRAIARALLAEGVQVVIAARDADVLKSAAADLATATGGTVVPVIVDTGSDSSVQELVETAV
GELGGVDILVNNAARPGGAGGPGGAQALSTADVAADFNVKVLGYLRTAQAVAPHFIAQGWGRIINIGGLAARQVGLASGS
IRNVGVAALTKTLADELGAHGVTVNVVHPGLTLTGDHGGTVVLSDEHIQAAAARISIGRAITADEVASVVVFLASPLSVA
ITGESIAAGGGTQGPIHY
>Mature_258_residues
MDLRLSGRRAIVTGGSRGIGRAIARALLAEGVQVVIAARDADVLKSAAADLATATGGTVVPVIVDTGSDSSVQELVETAV
GELGGVDILVNNAARPGGAGGPGGAQALSTADVAADFNVKVLGYLRTAQAVAPHFIAQGWGRIINIGGLAARQVGLASGS
IRNVGVAALTKTLADELGAHGVTVNVVHPGLTLTGDHGGTVVLSDEHIQAAAARISIGRAITADEVASVVVFLASPLSVA
ITGESIAAGGGTQGPIHY

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=33.4630350194552, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=32, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=33.7349397590361, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI7705925, Length=261, Percent_Identity=34.4827586206897, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=30.46875, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=31.1023622047244, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=30, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=27.843137254902, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40254986, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI209862901, Length=205, Percent_Identity=32.6829268292683, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI19923983, Length=205, Percent_Identity=32.6829268292683, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI225579078, Length=220, Percent_Identity=28.6363636363636, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=30.5882352941176, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=33.0677290836653, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=31.1023622047244, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=27.6923076923077, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=29.0196078431373, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=30.1652892561983, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=26.9230769230769, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=30.4347826086957, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=30.5970149253731, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=30.7984790874525, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=29.8850574712644, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=31.0861423220974, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=29.9242424242424, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=31.0344827586207, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=30.0380228136882, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=28.030303030303, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=30.3030303030303, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=32.5670498084291, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=29.8892988929889, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=32.1969696969697, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=31.2741312741313, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=261, Percent_Identity=30.2681992337165, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=30.7984790874525, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=29.6992481203008, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=31.5384615384615, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=28.8973384030418, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=29.5719844357977, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=30.6772908366534, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=30.1115241635688, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=28.6259541984733, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=98, Percent_Identity=41.8367346938776, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=28.735632183908, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=261, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=261, Percent_Identity=29.8850574712644, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=197, Percent_Identity=27.9187817258883, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=197, Percent_Identity=27.9187817258883, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=31.1284046692607, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=261, Percent_Identity=26.8199233716475, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=27.4111675126904, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=33.4661354581673, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=30.6201550387597, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=29.6442687747036, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=26.7716535433071, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=30.5220883534137, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=27.4111675126904, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=30.1204819277108, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641232, Length=126, Percent_Identity=34.1269841269841, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25435; Mature: 25435

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRLSGRRAIVTGGSRGIGRAIARALLAEGVQVVIAARDADVLKSAAADLATATGGTVV
CCCEECCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCCEEE
PVIVDTGSDSSVQELVETAVGELGGVDILVNNAARPGGAGGPGGAQALSTADVAADFNVK
EEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEE
VLGYLRTAQAVAPHFIAQGWGRIINIGGLAARQVGLASGSIRNVGVAALTKTLADELGAH
EEEHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
GVTVNVVHPGLTLTGDHGGTVVLSDEHIQAAAARISIGRAITADEVASVVVFLASPLSVA
CEEEEEEECCEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEE
ITGESIAAGGGTQGPIHY
EECCEEECCCCCCCCCCC
>Mature Secondary Structure
MDLRLSGRRAIVTGGSRGIGRAIARALLAEGVQVVIAARDADVLKSAAADLATATGGTVV
CCCEECCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCCEEE
PVIVDTGSDSSVQELVETAVGELGGVDILVNNAARPGGAGGPGGAQALSTADVAADFNVK
EEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEE
VLGYLRTAQAVAPHFIAQGWGRIINIGGLAARQVGLASGSIRNVGVAALTKTLADELGAH
EEEHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
GVTVNVVHPGLTLTGDHGGTVVLSDEHIQAAAARISIGRAITADEVASVVVFLASPLSVA
CEEEEEEECCEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEE
ITGESIAAGGGTQGPIHY
EECCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]