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The map label for this gene is lat [H]

Identifier: 158314203

GI number: 158314203

Start: 2819179

End: 2820618

Strand: Direct

Name: lat [H]

Synonym: Franean1_2373

Alternate gene names: 158314203

Gene position: 2819179-2820618 (Clockwise)

Preceding gene: 158314198

Following gene: 158314204

Centisome position: 31.39

GC content: 73.89

Gene sequence:

>1440_bases
GTGGCCGTCATGAGTGTCGCGGGCCGCCCGGGCGGGGGGAGCCGTGCCCGGCCCGAGCCGGCCGAGGTGATCCCGATATT
GTCCCGGCACGTCCTGACCGACGGGTACGACGTCGTCTGCGACCTGACGGCCAGCACCGGCAGCACGATCGTCGACGCCC
GCACCGGGACGCGCTACCTCGACCTCTACAGCTTCTTCGCCTCCGCGCCGCTCGGGATCAACCCGCCGGCCCTGCTGGGC
GACCCGGAGTTCCTCACCGAGCTCGCCCGGGCGGCCGTCAACAAGCCGGCGAACCCCGACATGGCGACCGCCGCCTACGC
CGAGTTCGTCGAGACCTTCGCGCGGGTGCTGGGCGACCCGGAGCTGCCGCACCTGTTCTTCGTCGAGGGCGGGTCGGCAG
CCGTCGAGAACGCCCTCAAGTGCGCGTTCGACTGGAAGAGCCGGCACAACGAGGCACACGGGCGGCCCGCCGAGCTCGGC
GGGCGGGTGCTGCACCTGCGGTCGGCGTTCCACGGCCGCGGCGGGTACACCCTCTCGGTGACCAACACCGAGCCGGTCAA
GACCGCGCGCTTCCCGGTCTTCGACTGGCCCCGGGTCGACTGCCCGGCGGTGACCTTCCCCTGCACCGGCGCGGCGCTGG
ACGCGGTGGTCGCCGCCGAGCGGCGCGCGCTCGCGCAGGCCGAGGAGGCGTTCGCCCGCCACCGCCACGACATCGCATGC
TTCCTCGCCGAGCCGATCCAGGCCGAGGGCGGGGACAACCACCTCCGCGGCGAGTTCCTGCGCGCGATGGCGGCGCTGTG
CGAGCGTCACGACGCGCTGTTCGTCGTCGACGAGGTGCAGACCGGGGTGGGCCTGACCGGCTCCGCCTGGGCGCACACCC
AGCTCGGCCTGCGCCCCGACGTCGTCGCGTTCGGCAAGAAGGTCCAGCTCGGCGGGGTGATGGCCGGGCGGCGGGTGGAC
GAGGTCGCCGACAACGTCTTCCGGCTGCCCGGCCGGATCAGCTCCACCTGGGGCGGCGGGCTCGTCGACATGGTGCGTTC
CCGGCGAATGCTGGAGATCATGGAGTCGGAGCGGCTGTTCGACCGGGCCGCCGTCCTGGGCTCCGATCTGCTGGCCGGAC
TCGAGGAGCTGGCCCAGCGCCACCCCCGCCTGCTGCGCAACGCCCGCGGGCGTGGGTTGATGTGCGCCGTGGACCTGCCC
GACCGTGCCCTGCGCGACGAGGTCGTCCGGCTGCTGCGGGAACGCGAGCACGTCCTGCTGCTGCCGGCGGGGGAGCGGGC
GCTGCGCTTCCGCCCGGCGCTCACCATCGGCGCCGAGGAGCTCGCCGCCGGGGTGCGCGCCCTCGACCGGGTGCTCACCC
ACCTCGTTTCGCCGGAGCCCGAGGCTGCTGAGAAGGCCTCGCCGCCGGCCACCGCCACGCAGGAGAAAGGACTGAGATGA

Upstream 100 bases:

>100_bases
TCCATGATCGGATCGCGGTTCCGCTCGGTAACCGCGACCCTGATGCCCTGACGCGGACGTCCTCGTGGGACGGCCGCGCG
GTGCTGGAAGGAGGCCGGCC

Downstream 100 bases:

>100_bases
CACTCGTTCATCCACGCCGGGTGGCGGCGGTGATCGGCGGCCGCCAGCACGACCTGTACGCCGCGGCCGGCCCGGCGGGC
ATCGCCCCGGAGACCGCGCG

Product: L-lysine aminotransferase

Products: NA

Alternate protein names: L-lysine aminotransferase; Lysine 6-aminotransferase [H]

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MAVMSVAGRPGGGSRARPEPAEVIPILSRHVLTDGYDVVCDLTASTGSTIVDARTGTRYLDLYSFFASAPLGINPPALLG
DPEFLTELARAAVNKPANPDMATAAYAEFVETFARVLGDPELPHLFFVEGGSAAVENALKCAFDWKSRHNEAHGRPAELG
GRVLHLRSAFHGRGGYTLSVTNTEPVKTARFPVFDWPRVDCPAVTFPCTGAALDAVVAAERRALAQAEEAFARHRHDIAC
FLAEPIQAEGGDNHLRGEFLRAMAALCERHDALFVVDEVQTGVGLTGSAWAHTQLGLRPDVVAFGKKVQLGGVMAGRRVD
EVADNVFRLPGRISSTWGGGLVDMVRSRRMLEIMESERLFDRAAVLGSDLLAGLEELAQRHPRLLRNARGRGLMCAVDLP
DRALRDEVVRLLREREHVLLLPAGERALRFRPALTIGAEELAAGVRALDRVLTHLVSPEPEAAEKASPPATATQEKGLR

Sequences:

>Translated_479_residues
MAVMSVAGRPGGGSRARPEPAEVIPILSRHVLTDGYDVVCDLTASTGSTIVDARTGTRYLDLYSFFASAPLGINPPALLG
DPEFLTELARAAVNKPANPDMATAAYAEFVETFARVLGDPELPHLFFVEGGSAAVENALKCAFDWKSRHNEAHGRPAELG
GRVLHLRSAFHGRGGYTLSVTNTEPVKTARFPVFDWPRVDCPAVTFPCTGAALDAVVAAERRALAQAEEAFARHRHDIAC
FLAEPIQAEGGDNHLRGEFLRAMAALCERHDALFVVDEVQTGVGLTGSAWAHTQLGLRPDVVAFGKKVQLGGVMAGRRVD
EVADNVFRLPGRISSTWGGGLVDMVRSRRMLEIMESERLFDRAAVLGSDLLAGLEELAQRHPRLLRNARGRGLMCAVDLP
DRALRDEVVRLLREREHVLLLPAGERALRFRPALTIGAEELAAGVRALDRVLTHLVSPEPEAAEKASPPATATQEKGLR
>Mature_478_residues
AVMSVAGRPGGGSRARPEPAEVIPILSRHVLTDGYDVVCDLTASTGSTIVDARTGTRYLDLYSFFASAPLGINPPALLGD
PEFLTELARAAVNKPANPDMATAAYAEFVETFARVLGDPELPHLFFVEGGSAAVENALKCAFDWKSRHNEAHGRPAELGG
RVLHLRSAFHGRGGYTLSVTNTEPVKTARFPVFDWPRVDCPAVTFPCTGAALDAVVAAERRALAQAEEAFARHRHDIACF
LAEPIQAEGGDNHLRGEFLRAMAALCERHDALFVVDEVQTGVGLTGSAWAHTQLGLRPDVVAFGKKVQLGGVMAGRRVDE
VADNVFRLPGRISSTWGGGLVDMVRSRRMLEIMESERLFDRAAVLGSDLLAGLEELAQRHPRLLRNARGRGLMCAVDLPD
RALRDEVVRLLREREHVLLLPAGERALRFRPALTIGAEELAAGVRALDRVLTHLVSPEPEAAEKASPPATATQEKGLR

Specific function: 4-aminobutyrate (GABA) degradation. [C]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI188536080, Length=443, Percent_Identity=31.3769751693002, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI38679950, Length=443, Percent_Identity=31.3769751693002, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI38679946, Length=443, Percent_Identity=31.3769751693002, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI4557809, Length=410, Percent_Identity=27.0731707317073, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI284507298, Length=220, Percent_Identity=31.8181818181818, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI13994255, Length=429, Percent_Identity=25.1748251748252, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI24119277, Length=359, Percent_Identity=27.2980501392758, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI226442709, Length=256, Percent_Identity=27.34375, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI37574042, Length=256, Percent_Identity=27.34375, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI226442705, Length=256, Percent_Identity=27.34375, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1789016, Length=368, Percent_Identity=29.0760869565217, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI145693181, Length=446, Percent_Identity=25.7847533632287, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788044, Length=415, Percent_Identity=27.2289156626506, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789759, Length=449, Percent_Identity=25.8351893095768, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787560, Length=441, Percent_Identity=26.7573696145125, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786991, Length=279, Percent_Identity=25.089605734767, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17541228, Length=449, Percent_Identity=32.5167037861915, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI25144271, Length=422, Percent_Identity=27.0142180094787, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25144274, Length=310, Percent_Identity=27.741935483871, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71992977, Length=402, Percent_Identity=25.6218905472637, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32564660, Length=372, Percent_Identity=25.2688172043011, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321456, Length=438, Percent_Identity=28.9954337899543, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324432, Length=419, Percent_Identity=25.7756563245823, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=407, Percent_Identity=28.992628992629, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281366494, Length=434, Percent_Identity=30.4147465437788, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24667139, Length=434, Percent_Identity=30.4147465437788, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24667143, Length=434, Percent_Identity=30.4147465437788, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI21357415, Length=417, Percent_Identity=24.9400479616307, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI161085790, Length=447, Percent_Identity=26.1744966442953, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28574759, Length=369, Percent_Identity=27.6422764227642, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356575, Length=426, Percent_Identity=24.8826291079812, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR017657
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.36 [H]

Molecular weight: Translated: 51765; Mature: 51634

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVMSVAGRPGGGSRARPEPAEVIPILSRHVLTDGYDVVCDLTASTGSTIVDARTGTRYL
CCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCHHH
DLYSFFASAPLGINPPALLGDPEFLTELARAAVNKPANPDMATAAYAEFVETFARVLGDP
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
ELPHLFFVEGGSAAVENALKCAFDWKSRHNEAHGRPAELGGRVLHLRSAFHGRGGYTLSV
CCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEHHHHCCCCCEEEEE
TNTEPVKTARFPVFDWPRVDCPAVTFPCTGAALDAVVAAERRALAQAEEAFARHRHDIAC
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
FLAEPIQAEGGDNHLRGEFLRAMAALCERHDALFVVDEVQTGVGLTGSAWAHTQLGLRPD
EEECCHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHCCCCCCCC
VVAFGKKVQLGGVMAGRRVDEVADNVFRLPGRISSTWGGGLVDMVRSRRMLEIMESERLF
HHHHCCEEEECCHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DRAAVLGSDLLAGLEELAQRHPRLLRNARGRGLMCAVDLPDRALRDEVVRLLREREHVLL
HHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEE
LPAGERALRFRPALTIGAEELAAGVRALDRVLTHLVSPEPEAAEKASPPATATQEKGLR
EECCCCCEEECCCCEECHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHCCCC
>Mature Secondary Structure 
AVMSVAGRPGGGSRARPEPAEVIPILSRHVLTDGYDVVCDLTASTGSTIVDARTGTRYL
CEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCHHH
DLYSFFASAPLGINPPALLGDPEFLTELARAAVNKPANPDMATAAYAEFVETFARVLGDP
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
ELPHLFFVEGGSAAVENALKCAFDWKSRHNEAHGRPAELGGRVLHLRSAFHGRGGYTLSV
CCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEHHHHCCCCCEEEEE
TNTEPVKTARFPVFDWPRVDCPAVTFPCTGAALDAVVAAERRALAQAEEAFARHRHDIAC
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
FLAEPIQAEGGDNHLRGEFLRAMAALCERHDALFVVDEVQTGVGLTGSAWAHTQLGLRPD
EEECCHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHCCCCCCCC
VVAFGKKVQLGGVMAGRRVDEVADNVFRLPGRISSTWGGGLVDMVRSRRMLEIMESERLF
HHHHCCEEEECCHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DRAAVLGSDLLAGLEELAQRHPRLLRNARGRGLMCAVDLPDRALRDEVVRLLREREHVLL
HHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEE
LPAGERALRFRPALTIGAEELAAGVRALDRVLTHLVSPEPEAAEKASPPATATQEKGLR
EECCCCCEEECCCCEECHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]