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The map label for this gene is 158314052

Identifier: 158314052

GI number: 158314052

Start: 2654930

End: 2655937

Strand: Direct

Name: 158314052

Synonym: Franean1_2219

Alternate gene names: NA

Gene position: 2654930-2655937 (Clockwise)

Preceding gene: 158314050

Following gene: 158314055

Centisome position: 29.56

GC content: 78.17

Gene sequence:

>1008_bases
ATGGACGTCGTGCCCGCGCGGGACGCCGCGGTGCTCCAGGGGCGGGTGCTCCCGCCCGGCCCGTCCGGTACGCGTGGCGC
GGCGGCGGGGCGGCGCCGGGTCGCGGTTGTCGGTGCCGGCGCGGTGGGCGGGTACTTCGCCGCGCGCGCGGCCGAGGCCG
GTGCCGAGGTGCTCCTCTGCGTGCGCGGCGGCGGCTTCGACCGCCTGCGCATCGTCCGGGCCGGCCCCGCGGCCGGCGGA
GGCGTCACCGAGCTGCGGCTGCCGGTGGTTCGCGACCCCGCCGATCTCGGCGGGCCGGTGGACTGGATCGTGCTGGCCAC
GAAGGCCCATCAGACCCCGGCCGCGATGGGATGGCTGCATGCCGGCCTGGGAGCAGGGACCGGAGTGGTGGTCGCGCAGA
ACGGGGTCGACCACGCCGAGCGGGTCAGCCCACCCGTCCCGCGTGACGCCGTCCTGCCGGCGGTGGTGTACCTCAATGCC
GAGCTGGAGCGGCCGGGTGTGGTCCGGCATCTGGCCTACGGGGTGCTGCAGGTACCCGACGGCCCGCTGGGCGAGCGCTT
CGCCGGGGTGCTGCCGCCCGGCGACGTCCGGCTCGTCCCCGACTTCGCCACGGCCGCCTGGTCGAAGCTGCTCAGCAACA
GCGCGGCGAACTCGCTGACGGCGCTGACGGCACGCGGTCTCGAGGTGCTCGCCCGCCCGGATGTCGGCGAGCTCGCGCTG
GCGGTCATGCGGGAGACCGCCTCGGTGGCCCGGGCCGCCGGCGCGCGCATAGCCGCGGACGCCCCGGAGCGCACGCTCGC
CCGGCTGGGCCACCAGCCGCCCGGCGCGGGGACGTCCATGCTGCGTGACCGGCTGGCGGGCCGCCCGCTGGAGCACGACG
CGCTGCTCGGAGCGGTCGTCCGGACGGGCGGGCGGCTCGGGGTGCCCACGCCGACCTGCGCCGTGCTGCTCCCCGTGCTC
GCCGCCCTCAGCGCCAGCCCTGCCGTGGGACCGGGTGGGACGCCCTGA

Upstream 100 bases:

>100_bases
GCAGCTGCCCGGCCGGGCCGGGCCGGATCCGGTCGCCAGGCACCGGACGGGTGAGCCCCGACCGGTCGGCGGACCCGCGA
GATGGTGGCAGGCTCTGCGT

Downstream 100 bases:

>100_bases
CGGTCAGGACGTGCGTTCGGGTACCGCGTCGGCGACGATGTGCTCCGCGATCGCCAGCGACGCGGTCGCACCCGGGGACG
GGGCGTTGCGCACGTGGACG

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDVVPARDAAVLQGRVLPPGPSGTRGAAAGRRRVAVVGAGAVGGYFAARAAEAGAEVLLCVRGGGFDRLRIVRAGPAAGG
GVTELRLPVVRDPADLGGPVDWIVLATKAHQTPAAMGWLHAGLGAGTGVVVAQNGVDHAERVSPPVPRDAVLPAVVYLNA
ELERPGVVRHLAYGVLQVPDGPLGERFAGVLPPGDVRLVPDFATAAWSKLLSNSAANSLTALTARGLEVLARPDVGELAL
AVMRETASVARAAGARIAADAPERTLARLGHQPPGAGTSMLRDRLAGRPLEHDALLGAVVRTGGRLGVPTPTCAVLLPVL
AALSASPAVGPGGTP

Sequences:

>Translated_335_residues
MDVVPARDAAVLQGRVLPPGPSGTRGAAAGRRRVAVVGAGAVGGYFAARAAEAGAEVLLCVRGGGFDRLRIVRAGPAAGG
GVTELRLPVVRDPADLGGPVDWIVLATKAHQTPAAMGWLHAGLGAGTGVVVAQNGVDHAERVSPPVPRDAVLPAVVYLNA
ELERPGVVRHLAYGVLQVPDGPLGERFAGVLPPGDVRLVPDFATAAWSKLLSNSAANSLTALTARGLEVLARPDVGELAL
AVMRETASVARAAGARIAADAPERTLARLGHQPPGAGTSMLRDRLAGRPLEHDALLGAVVRTGGRLGVPTPTCAVLLPVL
AALSASPAVGPGGTP
>Mature_335_residues
MDVVPARDAAVLQGRVLPPGPSGTRGAAAGRRRVAVVGAGAVGGYFAARAAEAGAEVLLCVRGGGFDRLRIVRAGPAAGG
GVTELRLPVVRDPADLGGPVDWIVLATKAHQTPAAMGWLHAGLGAGTGVVVAQNGVDHAERVSPPVPRDAVLPAVVYLNA
ELERPGVVRHLAYGVLQVPDGPLGERFAGVLPPGDVRLVPDFATAAWSKLLSNSAANSLTALTARGLEVLARPDVGELAL
AVMRETASVARAAGARIAADAPERTLARLGHQPPGAGTSMLRDRLAGRPLEHDALLGAVVRTGGRLGVPTPTCAVLLPVL
AALSASPAVGPGGTP

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33729; Mature: 33729

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVVPARDAAVLQGRVLPPGPSGTRGAAAGRRRVAVVGAGAVGGYFAARAAEAGAEVLLC
CCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEE
VRGGGFDRLRIVRAGPAAGGGVTELRLPVVRDPADLGGPVDWIVLATKAHQTPAAMGWLH
EECCCCCEEEEEEECCCCCCCCEEEECCEECCCHHHCCCEEEEEEEECCCCCHHHHHHHH
AGLGAGTGVVVAQNGVDHAERVSPPVPRDAVLPAVVYLNAELERPGVVRHLAYGVLQVPD
HCCCCCCEEEEECCCCCHHHHCCCCCCCHHHCCEEEEEECCCCCCHHHHHHHHCEEECCC
GPLGERFAGVLPPGDVRLVPDFATAAWSKLLSNSAANSLTALTARGLEVLARPDVGELAL
CCCCHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCHHHHHH
AVMRETASVARAAGARIAADAPERTLARLGHQPPGAGTSMLRDRLAGRPLEHDALLGAVV
HHHHHHHHHHHHHCCEEECCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
RTGGRLGVPTPTCAVLLPVLAALSASPAVGPGGTP
HCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDVVPARDAAVLQGRVLPPGPSGTRGAAAGRRRVAVVGAGAVGGYFAARAAEAGAEVLLC
CCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEE
VRGGGFDRLRIVRAGPAAGGGVTELRLPVVRDPADLGGPVDWIVLATKAHQTPAAMGWLH
EECCCCCEEEEEEECCCCCCCCEEEECCEECCCHHHCCCEEEEEEEECCCCCHHHHHHHH
AGLGAGTGVVVAQNGVDHAERVSPPVPRDAVLPAVVYLNAELERPGVVRHLAYGVLQVPD
HCCCCCCEEEEECCCCCHHHHCCCCCCCHHHCCEEEEEECCCCCCHHHHHHHHCEEECCC
GPLGERFAGVLPPGDVRLVPDFATAAWSKLLSNSAANSLTALTARGLEVLARPDVGELAL
CCCCHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCHHHHHH
AVMRETASVARAAGARIAADAPERTLARLGHQPPGAGTSMLRDRLAGRPLEHDALLGAVV
HHHHHHHHHHHHHCCEEECCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
RTGGRLGVPTPTCAVLLPVLAALSASPAVGPGGTP
HCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]