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The map label for this gene is wecB [H]

Identifier: 158313997

GI number: 158313997

Start: 2596239

End: 2597435

Strand: Direct

Name: wecB [H]

Synonym: Franean1_2163

Alternate gene names: 158313997

Gene position: 2596239-2597435 (Clockwise)

Preceding gene: 158313996

Following gene: 158313998

Centisome position: 28.9

GC content: 71.76

Gene sequence:

>1197_bases
GTGCCCGACCAGGGCGGTCTGCCCGCGGCCGGCCTGCACGCCGTCGTCATCGCCGGCGCGAGACCGAACTTCATCAAGGT
GAAGCCTGTCCTCGACGCGCTGGCGGCCGACGGTGCCCGAAGCAGCTTCGTGCACACGGGGCAGCACTATGACGAGGCGA
TGAGTGACGTCTTCTTCGCCGATCTCGGGCTGCGGCAGCCCGACTACCATCTGGAGGCGGGATCCGGCTCGCACGCGGTG
CAGACCGCGGCTGTGATGACCGCGTTCGAGCCGCTGCTGGCGCGGCTTGCACCCGATGTCGTCGTGGTCGTCGGCGACGT
GAACTCGACGTTGGCGTGCGCGCTCGTCGCGGCGAAGGCGAACGTCCCGGTCGCCCACGTCGAGGCCGGCCTGCGCAGCG
GTGACCGGACGATGCCCGAGGAGATCAACCGGATCGTCACAGACCGTGTGTCGGACCTGTTGTTCGCTCCCAGCCCCGAA
GGTGTCGTCCACCTCCTCTCCGAGGGTGCGCGACCGGAGTCGGTCCACCTCGCTGGCAATGTCATGGTCGACACGCTGCT
CGCCTGCCGGGAGCGGGCCCGTTCCCGCCCCGTGCTCGCCGATCTGGGCCTGACCCCCGGGGAGTACGGCCTGGTGACAC
TGCATCGGCCGAGCAACGTCGACGACCCGGCGGTACTCGACGGGCTGCTCACGGCGCTGGGCGAGATCGCGCGCCGCTGC
CCGCTGGTGTTCCCCGTTCACCCGCGTACCGCCAGCCGCCTGGCCGGGCGGCTGCCGGACGGGGTGCGGGCACTCGGGCC
GGCTGGCTACCTGGACTGCGTCGCGCTTCAGATGGGTGCGCGACTGGTGCTCACCGATTCGGGTGGTGTCCAGGAGGAGT
CCACGGTGCTGGGTGTTCCGTGTCTGACCCTGCGGGAGAGCACCGAGCGGCCGATCACGGTCACCGAGGGGACGAACCGG
GTGGTGGGCTGTTCTCCAGCGGCGATCATGGCGGGCGCGTTCGAGGTGCTCGACCGCCCACCACCGCCGCGTTGTCCCGA
TCTGTGGGACGGGCACGCGGGCCGGCGGATCTCCGCGGTGCTCGGGCGGACCCTCGAACGTCGGGCTCGTCGTGGCGGCG
GGTCCCGCCCGCGTGGGCGGGCGGAGGCCGTGCCCGACCCCCTGCTGCCGACATCGCCTGCCGATCGCGGAGCGTGA

Upstream 100 bases:

>100_bases
CGGTCGGTCGGCCGCTTTCGTCCGTGCCGGGTATGCCCGCGGTGCGCAAGACAGCCGACGGCCCTGCGCGCGCTCGGACA
GCGGCGCCGTGACCGCGCTG

Downstream 100 bases:

>100_bases
CACACCGTAATGCTGTTGTGTAGCTGACAGTATTTAGTGAGTCACAATAGGTTCATGACTTCTTCGGGAAAGCTGGTGGT
GGTCGGCCAGGGGTACGTAG

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MPDQGGLPAAGLHAVVIAGARPNFIKVKPVLDALAADGARSSFVHTGQHYDEAMSDVFFADLGLRQPDYHLEAGSGSHAV
QTAAVMTAFEPLLARLAPDVVVVVGDVNSTLACALVAAKANVPVAHVEAGLRSGDRTMPEEINRIVTDRVSDLLFAPSPE
GVVHLLSEGARPESVHLAGNVMVDTLLACRERARSRPVLADLGLTPGEYGLVTLHRPSNVDDPAVLDGLLTALGEIARRC
PLVFPVHPRTASRLAGRLPDGVRALGPAGYLDCVALQMGARLVLTDSGGVQEESTVLGVPCLTLRESTERPITVTEGTNR
VVGCSPAAIMAGAFEVLDRPPPPRCPDLWDGHAGRRISAVLGRTLERRARRGGGSRPRGRAEAVPDPLLPTSPADRGA

Sequences:

>Translated_398_residues
MPDQGGLPAAGLHAVVIAGARPNFIKVKPVLDALAADGARSSFVHTGQHYDEAMSDVFFADLGLRQPDYHLEAGSGSHAV
QTAAVMTAFEPLLARLAPDVVVVVGDVNSTLACALVAAKANVPVAHVEAGLRSGDRTMPEEINRIVTDRVSDLLFAPSPE
GVVHLLSEGARPESVHLAGNVMVDTLLACRERARSRPVLADLGLTPGEYGLVTLHRPSNVDDPAVLDGLLTALGEIARRC
PLVFPVHPRTASRLAGRLPDGVRALGPAGYLDCVALQMGARLVLTDSGGVQEESTVLGVPCLTLRESTERPITVTEGTNR
VVGCSPAAIMAGAFEVLDRPPPPRCPDLWDGHAGRRISAVLGRTLERRARRGGGSRPRGRAEAVPDPLLPTSPADRGA
>Mature_397_residues
PDQGGLPAAGLHAVVIAGARPNFIKVKPVLDALAADGARSSFVHTGQHYDEAMSDVFFADLGLRQPDYHLEAGSGSHAVQ
TAAVMTAFEPLLARLAPDVVVVVGDVNSTLACALVAAKANVPVAHVEAGLRSGDRTMPEEINRIVTDRVSDLLFAPSPEG
VVHLLSEGARPESVHLAGNVMVDTLLACRERARSRPVLADLGLTPGEYGLVTLHRPSNVDDPAVLDGLLTALGEIARRCP
LVFPVHPRTASRLAGRLPDGVRALGPAGYLDCVALQMGARLVLTDSGGVQEESTVLGVPCLTLRESTERPITVTEGTNRV
VGCSPAAIMAGAFEVLDRPPPPRCPDLWDGHAGRRISAVLGRTLERRARRGGGSRPRGRAEAVPDPLLPTSPADRGA

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=339, Percent_Identity=34.5132743362832, Blast_Score=141, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41750; Mature: 41619

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDQGGLPAAGLHAVVIAGARPNFIKVKPVLDALAADGARSSFVHTGQHYDEAMSDVFFA
CCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHCCCCHHHHEECCHHHHHHHHHHHHH
DLGLRQPDYHLEAGSGSHAVQTAAVMTAFEPLLARLAPDVVVVVGDVNSTLACALVAAKA
HCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCC
NVPVAHVEAGLRSGDRTMPEEINRIVTDRVSDLLFAPSPEGVVHLLSEGARPESVHLAGN
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCCEEEEEHH
VMVDTLLACRERARSRPVLADLGLTPGEYGLVTLHRPSNVDDPAVLDGLLTALGEIARRC
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
PLVFPVHPRTASRLAGRLPDGVRALGPAGYLDCVALQMGARLVLTDSGGVQEESTVLGVP
CEEEECCCCHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCEEEEECCCCCCCCCEEECCC
CLTLRESTERPITVTEGTNRVVGCSPAAIMAGAFEVLDRPPPPRCPDLWDGHAGRRISAV
CHHHHCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
LGRTLERRARRGGGSRPRGRAEAVPDPLLPTSPADRGA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDQGGLPAAGLHAVVIAGARPNFIKVKPVLDALAADGARSSFVHTGQHYDEAMSDVFFA
CCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHCCCCHHHHEECCHHHHHHHHHHHHH
DLGLRQPDYHLEAGSGSHAVQTAAVMTAFEPLLARLAPDVVVVVGDVNSTLACALVAAKA
HCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCC
NVPVAHVEAGLRSGDRTMPEEINRIVTDRVSDLLFAPSPEGVVHLLSEGARPESVHLAGN
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCCEEEEEHH
VMVDTLLACRERARSRPVLADLGLTPGEYGLVTLHRPSNVDDPAVLDGLLTALGEIARRC
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
PLVFPVHPRTASRLAGRLPDGVRALGPAGYLDCVALQMGARLVLTDSGGVQEESTVLGVP
CEEEECCCCHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCEEEEECCCCCCCCCEEECCC
CLTLRESTERPITVTEGTNRVVGCSPAAIMAGAFEVLDRPPPPRCPDLWDGHAGRRISAV
CHHHHCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
LGRTLERRARRGGGSRPRGRAEAVPDPLLPTSPADRGA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA