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The map label for this gene is afr [H]

Identifier: 158313996

GI number: 158313996

Start: 2593527

End: 2595923

Strand: Direct

Name: afr [H]

Synonym: Franean1_2162

Alternate gene names: 158313996

Gene position: 2593527-2595923 (Clockwise)

Preceding gene: 158313986

Following gene: 158313997

Centisome position: 28.87

GC content: 74.8

Gene sequence:

>2397_bases
GTGAGGCAGGTGGTCCAGGCCGCCGGCGGTGGAGAGGTTCGGGTCGTCGACACTCCGATTCCCTCCATCGGGGCGACCGA
GGTACTCGTGGAGACGGCGGCCACCATCGTGTCCGCCGGTACCGAGCGGGCGGTGACGACGCTCGCCCGGTCCGGCTTGC
TGGCCAAGGCGCGGGCACGCCCCGACCTCGTCCGCCGGGTGGCGGAGAAGGCCAGAGCGGACGGGATCGGCGAGGCGGTC
CGCTCGGTCCGCGACCGGCTCGCCTCCGAACTGCCCCTGGGCTACAGCGGGGCCGGTCGGGCCGTCCGGGTGGGTACCGC
CGTCGAGGGCATCCGACCCGGCGATCTGGTGGTCACCGGCGGGGCTGGCTGGGCGAACCACGCCGAGTTCCAGGCGGTAC
CCGGACTGCTGTGCGCGCGGGTGCCGGACGGGGTTCCCGAGGCCGACGCCGCCTTCGCGACCATCGCCGCCATCGCGCTG
CACGGGCTGCGTCTGGCCGAGGTCGGACCGGGAGCGAAGGTGGTCGTCGTCGGGCTGGGCCTCATCGGCCAGCTCGCCGC
CCGCATCGCCATGGCCAGTGGATACGACGTGGCCGGCGTGGACCTCGCGGACCTGCCGCTGACCACCGCCGCGGCCAGCG
GAGTGCGGGCGCTGCGCGAGTCCGGCGACGCCACCACGGCCGCGGTGCGGGAGTGGAGCCGGGGGCGCGGGGCGGATGCG
GTGCTGATCTGCGCGGCGGGCCGGTCCGGCGACCCGGTGATGCGGGCGACGGAGTTCGCCCGCGACCGGGCGCAGCTCGT
CGTCGTCGGGGACGTCCCGCTGGGCCTGACGCGTGCGCCGTTCTACGAGAAGGAGCTCGTCCTGCGCTTCGCGCGGTCGT
ACGGCCCCGGCCGGTACGAGCGTGGCTATGAAGAATGGGGGGTGGACTACCCGGCGGGCCAGGTCCGCTGGACGGAGGGC
CGCAACCAGGAGGCGGTGCTCGACCTGCTCGCCGCCGGCCGGCTGTCCGTGGCCGACCTGGTCACTCACGCCTTCCCGCT
CGAGCAGGCCGCGGCCGCCTACGATCTGGTGGCGACGCGACGGGAGCCGTACCTGGCCATCCGGTTCGACTACCCGCGCC
GCGCCGAGCTGACCGAGCCGGTGGAGGGCGTCCTTTCCACGGAGGGCACTCCGCCTGCGGAGGGCACCGCCCCGACCGAG
GGTTCCACCCCGGGGGACGCGCGGCAGGTCGGACAGCACACGCAGCGGGTGGCGCGTCGGGTCGGTCCGCCCGGCCGGCG
CCGGGGTGACCGTGTCGGTTGGATCGGCGCCGGGAACTTCTCCGGCTCGGTGTTGCTGCCGGCTTTTCGTGCTGCCGGTT
TCGACCGTTTCACCAGCGTCGCTTCGGCCAGTGGGCGGTCGGCTCGCGCCTTCGCCGACCGGCATGGGTTCCAGGGGGCC
GCCACCGGGGTCGACGAGCTGCTCGACGACGGCGACCTCGATGTGGTGGTGATCGCGACGCCGCACTCCACGCACGCCCG
GCTGGCGGCGGCGGCACTCGAACGGGGCCGGCACGTGTGGTGTGAGAAGCCGTTGGCCCTCGACCTGGCCGAGCTGGAGA
TGGTCGAGCAGGCGGCGGCCGTGGGCGGCGGTGTTCTGATGGTGGGTCTCAACCGCAGGTTCTCCCCGGCGGTCGTCGCG
GCCCGGCGGCGCCTGGCCGAGCGGGACGGCCCGCTGAGCCTGGTGTACCGGGTCGCGGCCGGTCCCGTACCCGCTGACCA
CTGGTACGGCGACCGGGTCGAGGGCGGCCGGCTGCTGGGCGAGGTCTGCCACTTCGTCGACACCTGTGCGGCGCTGGCGG
GCAGCGGGGTCGAGGCGGCGACAGTGGTGCCCGGCCGCGGTGGTGAGGCGCTGCTGGCCGAAGACCTGGCCGTGACGTTG
CGGCACGTCGACGGAAGCCTGTCGACCATCGCGTACAGCTCCGCCCGCCCCCGGGCCTGCCGGAAGGAGACGGTCGAGGC
TCTCGCCGGCCGGCGTCACCTGCGCATCGACGACTTCCGGGAGCTGGTGGTCGACGGCGGCTCGGAATGGAAGGGCGCGC
AGGACAAGGGGCACCGGGCGGCGGCCGGTGCGTTCCTGCGGATGTGCCGCGGTGGCGCGACCGACGTGACGGCCGAGCTG
ATCGCGTCGTCCCGGGCGACGCTCGTCGCCGCCGCGAGTCTCGACACCGGTCTTCCGCAGTCAGTGGAGGCGCCGCTCAC
CGACCCGGCTGCCATCGATCCGGCCGTTCCTCGCCGCGCGAGTTCGGAACGGGAGAGCGCGGTCGGGGTACCGGCGGCGC
GGACGGCGGAACCGGACAGCGCGCCGGCTGCTCGGCCGGCCACTCCGACCCGAAGCGACGAACCCGGCGCAGGCTGA

Upstream 100 bases:

>100_bases
CAACTACGCTCCGCAACATGATGCGAGTGCGAGTGTCCGACCCGTCGCGGAGCCGCGGATCTTCTGCGCGGCAGGTCCAG
GCGATGGGCCGGGATCTCCG

Downstream 100 bases:

>100_bases
CCCTCCCTCCGCCCAGCGAGGGAAGAACGAACCGACCCCTCTGACACGGAAGGAGCTACCCGGTGGACCGGAGACAGGAG
GAAGGGCAATCGTGCCTCGC

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Anhydrofructose reductase; 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) [H]

Number of amino acids: Translated: 798; Mature: 798

Protein sequence:

>798_residues
MRQVVQAAGGGEVRVVDTPIPSIGATEVLVETAATIVSAGTERAVTTLARSGLLAKARARPDLVRRVAEKARADGIGEAV
RSVRDRLASELPLGYSGAGRAVRVGTAVEGIRPGDLVVTGGAGWANHAEFQAVPGLLCARVPDGVPEADAAFATIAAIAL
HGLRLAEVGPGAKVVVVGLGLIGQLAARIAMASGYDVAGVDLADLPLTTAAASGVRALRESGDATTAAVREWSRGRGADA
VLICAAGRSGDPVMRATEFARDRAQLVVVGDVPLGLTRAPFYEKELVLRFARSYGPGRYERGYEEWGVDYPAGQVRWTEG
RNQEAVLDLLAAGRLSVADLVTHAFPLEQAAAAYDLVATRREPYLAIRFDYPRRAELTEPVEGVLSTEGTPPAEGTAPTE
GSTPGDARQVGQHTQRVARRVGPPGRRRGDRVGWIGAGNFSGSVLLPAFRAAGFDRFTSVASASGRSARAFADRHGFQGA
ATGVDELLDDGDLDVVVIATPHSTHARLAAAALERGRHVWCEKPLALDLAELEMVEQAAAVGGGVLMVGLNRRFSPAVVA
ARRRLAERDGPLSLVYRVAAGPVPADHWYGDRVEGGRLLGEVCHFVDTCAALAGSGVEAATVVPGRGGEALLAEDLAVTL
RHVDGSLSTIAYSSARPRACRKETVEALAGRRHLRIDDFRELVVDGGSEWKGAQDKGHRAAAGAFLRMCRGGATDVTAEL
IASSRATLVAAASLDTGLPQSVEAPLTDPAAIDPAVPRRASSERESAVGVPAARTAEPDSAPAARPATPTRSDEPGAG

Sequences:

>Translated_798_residues
MRQVVQAAGGGEVRVVDTPIPSIGATEVLVETAATIVSAGTERAVTTLARSGLLAKARARPDLVRRVAEKARADGIGEAV
RSVRDRLASELPLGYSGAGRAVRVGTAVEGIRPGDLVVTGGAGWANHAEFQAVPGLLCARVPDGVPEADAAFATIAAIAL
HGLRLAEVGPGAKVVVVGLGLIGQLAARIAMASGYDVAGVDLADLPLTTAAASGVRALRESGDATTAAVREWSRGRGADA
VLICAAGRSGDPVMRATEFARDRAQLVVVGDVPLGLTRAPFYEKELVLRFARSYGPGRYERGYEEWGVDYPAGQVRWTEG
RNQEAVLDLLAAGRLSVADLVTHAFPLEQAAAAYDLVATRREPYLAIRFDYPRRAELTEPVEGVLSTEGTPPAEGTAPTE
GSTPGDARQVGQHTQRVARRVGPPGRRRGDRVGWIGAGNFSGSVLLPAFRAAGFDRFTSVASASGRSARAFADRHGFQGA
ATGVDELLDDGDLDVVVIATPHSTHARLAAAALERGRHVWCEKPLALDLAELEMVEQAAAVGGGVLMVGLNRRFSPAVVA
ARRRLAERDGPLSLVYRVAAGPVPADHWYGDRVEGGRLLGEVCHFVDTCAALAGSGVEAATVVPGRGGEALLAEDLAVTL
RHVDGSLSTIAYSSARPRACRKETVEALAGRRHLRIDDFRELVVDGGSEWKGAQDKGHRAAAGAFLRMCRGGATDVTAEL
IASSRATLVAAASLDTGLPQSVEAPLTDPAAIDPAVPRRASSERESAVGVPAARTAEPDSAPAARPATPTRSDEPGAG
>Mature_798_residues
MRQVVQAAGGGEVRVVDTPIPSIGATEVLVETAATIVSAGTERAVTTLARSGLLAKARARPDLVRRVAEKARADGIGEAV
RSVRDRLASELPLGYSGAGRAVRVGTAVEGIRPGDLVVTGGAGWANHAEFQAVPGLLCARVPDGVPEADAAFATIAAIAL
HGLRLAEVGPGAKVVVVGLGLIGQLAARIAMASGYDVAGVDLADLPLTTAAASGVRALRESGDATTAAVREWSRGRGADA
VLICAAGRSGDPVMRATEFARDRAQLVVVGDVPLGLTRAPFYEKELVLRFARSYGPGRYERGYEEWGVDYPAGQVRWTEG
RNQEAVLDLLAAGRLSVADLVTHAFPLEQAAAAYDLVATRREPYLAIRFDYPRRAELTEPVEGVLSTEGTPPAEGTAPTE
GSTPGDARQVGQHTQRVARRVGPPGRRRGDRVGWIGAGNFSGSVLLPAFRAAGFDRFTSVASASGRSARAFADRHGFQGA
ATGVDELLDDGDLDVVVIATPHSTHARLAAAALERGRHVWCEKPLALDLAELEMVEQAAAVGGGVLMVGLNRRFSPAVVA
ARRRLAERDGPLSLVYRVAAGPVPADHWYGDRVEGGRLLGEVCHFVDTCAALAGSGVEAATVVPGRGGEALLAEDLAVTL
RHVDGSLSTIAYSSARPRACRKETVEALAGRRHLRIDDFRELVVDGGSEWKGAQDKGHRAAAGAFLRMCRGGATDVTAEL
IASSRATLVAAASLDTGLPQSVEAPLTDPAAIDPAVPRRASSERESAVGVPAARTAEPDSAPAARPATPTRSDEPGAG

Specific function: Catalyzes the NADPH-specific reduction of 1,5-anhydro-D- fructose to 1,5-anhydro-D-mannitol [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319955, Length=323, Percent_Identity=27.2445820433437, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322619, Length=323, Percent_Identity=27.2445820433437, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.292 [H]

Molecular weight: Translated: 82999; Mature: 82999

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQVVQAAGGGEVRVVDTPIPSIGATEVLVETAATIVSAGTERAVTTLARSGLLAKARAR
CCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHCC
PDLVRRVAEKARADGIGEAVRSVRDRLASELPLGYSGAGRAVRVGTAVEGIRPGDLVVTG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHCCCCCCCEEEEC
GAGWANHAEFQAVPGLLCARVPDGVPEADAAFATIAAIALHGLRLAEVGPGAKVVVVGLG
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEEEEHHH
LIGQLAARIAMASGYDVAGVDLADLPLTTAAASGVRALRESGDATTAAVREWSRGRGADA
HHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCE
VLICAAGRSGDPVMRATEFARDRAQLVVVGDVPLGLTRAPFYEKELVLRFARSYGPGRYE
EEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
RGYEEWGVDYPAGQVRWTEGRNQEAVLDLLAAGRLSVADLVTHAFPLEQAAAAYDLVATR
CCHHHCCCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHC
REPYLAIRFDYPRRAELTEPVEGVLSTEGTPPAEGTAPTEGSTPGDARQVGQHTQRVARR
CCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VGPPGRRRGDRVGWIGAGNFSGSVLLPAFRAAGFDRFTSVASASGRSARAFADRHGFQGA
CCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCCCCCH
ATGVDELLDDGDLDVVVIATPHSTHARLAAAALERGRHVWCEKPLALDLAELEMVEQAAA
HCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHH
VGGGVLMVGLNRRFSPAVVAARRRLAERDGPLSLVYRVAAGPVPADHWYGDRVEGGRLLG
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHH
EVCHFVDTCAALAGSGVEAATVVPGRGGEALLAEDLAVTLRHVDGSLSTIAYSSARPRAC
HHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHEEECCCCCHHH
RKETVEALAGRRHLRIDDFRELVVDGGSEWKGAQDKGHRAAAGAFLRMCRGGATDVTAEL
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
IASSRATLVAAASLDTGLPQSVEAPLTDPAAIDPAVPRRASSERESAVGVPAARTAEPDS
HHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCC
APAARPATPTRSDEPGAG
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRQVVQAAGGGEVRVVDTPIPSIGATEVLVETAATIVSAGTERAVTTLARSGLLAKARAR
CCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHCC
PDLVRRVAEKARADGIGEAVRSVRDRLASELPLGYSGAGRAVRVGTAVEGIRPGDLVVTG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHCCCCCCCEEEEC
GAGWANHAEFQAVPGLLCARVPDGVPEADAAFATIAAIALHGLRLAEVGPGAKVVVVGLG
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEEEEHHH
LIGQLAARIAMASGYDVAGVDLADLPLTTAAASGVRALRESGDATTAAVREWSRGRGADA
HHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCE
VLICAAGRSGDPVMRATEFARDRAQLVVVGDVPLGLTRAPFYEKELVLRFARSYGPGRYE
EEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
RGYEEWGVDYPAGQVRWTEGRNQEAVLDLLAAGRLSVADLVTHAFPLEQAAAAYDLVATR
CCHHHCCCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHC
REPYLAIRFDYPRRAELTEPVEGVLSTEGTPPAEGTAPTEGSTPGDARQVGQHTQRVARR
CCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VGPPGRRRGDRVGWIGAGNFSGSVLLPAFRAAGFDRFTSVASASGRSARAFADRHGFQGA
CCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCCCCCH
ATGVDELLDDGDLDVVVIATPHSTHARLAAAALERGRHVWCEKPLALDLAELEMVEQAAA
HCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHH
VGGGVLMVGLNRRFSPAVVAARRRLAERDGPLSLVYRVAAGPVPADHWYGDRVEGGRLLG
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHH
EVCHFVDTCAALAGSGVEAATVVPGRGGEALLAEDLAVTLRHVDGSLSTIAYSSARPRAC
HHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHEEECCCCCHHH
RKETVEALAGRRHLRIDDFRELVVDGGSEWKGAQDKGHRAAAGAFLRMCRGGATDVTAEL
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
IASSRATLVAAASLDTGLPQSVEAPLTDPAAIDPAVPRRASSERESAVGVPAARTAEPDS
HHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCC
APAARPATPTRSDEPGAG
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]