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The map label for this gene is csd [H]

Identifier: 158313924

GI number: 158313924

Start: 2514482

End: 2515807

Strand: Direct

Name: csd [H]

Synonym: Franean1_2089

Alternate gene names: 158313924

Gene position: 2514482-2515807 (Clockwise)

Preceding gene: 158313923

Following gene: 158313925

Centisome position: 27.99

GC content: 71.79

Gene sequence:

>1326_bases
ATGACCGTCGTCGAGACACGCGCGGCGGGGGCCGGCGCGCACGCCGGCGCCGGGTTCGACGTCGAGCGGGTCCGTCGCGA
CTTCCCGATCCTCGCCCGCACGGTGCACGACGGCCTGCCGCTGGTCTACCTCGACAGCGCCGCGACGTCGCAGAAGCCGC
TGGCCGTCCTCGACGCCGAGCGGACCTACTACGAGCGGCACAACGCCAACGTGCACCGCGGCATCCACGTGCTCGCCGAG
GAGGCCACGGCCCTCTACGAGGAGTCCCGGGACAAGATCGCGGCGTTCGTCGGCGCGCCCGACCGGCGCGAGATCGTGTT
CACGAAGAACTCCTCGGAGGCGCTGAACCTCGTCGCCTACGCGATGAGCAACGCCGTCACGGGCGGCCCCGAGGCGGAGC
GGTTCCGGCTCGGGCCGGGCGACGAGGTCGTCATCACCGAGATGGAGCACCACTCCAACCTGGTGCCCTGGCAGATGCTG
TGCGCGCGCACCGGCGCCACCCTGCGCTGGATCGGTCTCACCGAGGACGGCCGGCTCGACCTGGCGCACCTCGACGAGGT
CATCACCGACCGGGCGAAGATCGTCTCCTTCGTGCACCAGTCGAACATCCTCGGCACGGTCAACCCGGTCGCGACGATCG
TCGCCCGGGCTCGTGAGGTCGGGGCGCTCACCGTGCTCGACGGCTCCCAGTCGGTGCCGCACATGCCGATCGACGTCGTC
GACCTCGGGGTGGACTTCCTCGCCTTCACCGGGCACAAGATGTGCGGGCCCACCGGCATCGGCGTGCTGTGGGGGCGGCG
CGAGCTGCTCGAGGTGATGCCTCCGTTCCTCGGTGGTGGCGAGATGATCGAGGTCGTCACCATGGAGGCCTCGACCTACG
CGGCCCCGCCGCACCGCTTCGAGGCGGGCACCCCGATGATCTCCCAGGCGATCGGCCTGGGTGCCGCGGTGGACTACCTC
ACCGGCCTCGGCATGGACGCGGTCGCCGCGCACGAGCACGAGATCACCGCGTACGCGCTCGACGCGCTCGCGGGCGTCCC
GGGCCTGCGGGTCATCGGCCCGCCGACCGCCGAGGGCCGCGGCGGGGCGATCTCGTTCGCCCTGCGTGACTCCGAGGACC
GCCCGCTGCACCCGCACGACGTCGGCCAGATCCTGGACGAGCAGGGCGTCGCGGTGCGGGTCGGCCACCACTGCGCCCGC
CCGGTCTGCCTGCGCTACGGCGTGCCGGCGACCACCCGGGCCTCGTTCCACCTGTACACGAACACCGCCGACGTCGACGC
GTTGGTGGAAGGTCTCGGGCAGGTCAGGAGGTTCTTCCTGAAGTGA

Upstream 100 bases:

>100_bases
GGATCGTGGACGAGGGCGGCCCCGAGCTCGCGGCGACCCTGGAGGATTCCGGCTACGACCGGTACGTCAAGGGCGTGGAG
CCGGCGGCGGCGGCGGTCTC

Downstream 100 bases:

>100_bases
AGCTCGACTCCATGTACCAGGAGATCATCCTGGACCACTACCGCAACCCGCACCACCGCGGCCTGCGCGACCCGTTCGAT
GCCGAGGTGCACCACGTCAA

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTVVETRAAGAGAHAGAGFDVERVRRDFPILARTVHDGLPLVYLDSAATSQKPLAVLDAERTYYERHNANVHRGIHVLAE
EATALYEESRDKIAAFVGAPDRREIVFTKNSSEALNLVAYAMSNAVTGGPEAERFRLGPGDEVVITEMEHHSNLVPWQML
CARTGATLRWIGLTEDGRLDLAHLDEVITDRAKIVSFVHQSNILGTVNPVATIVARAREVGALTVLDGSQSVPHMPIDVV
DLGVDFLAFTGHKMCGPTGIGVLWGRRELLEVMPPFLGGGEMIEVVTMEASTYAAPPHRFEAGTPMISQAIGLGAAVDYL
TGLGMDAVAAHEHEITAYALDALAGVPGLRVIGPPTAEGRGGAISFALRDSEDRPLHPHDVGQILDEQGVAVRVGHHCAR
PVCLRYGVPATTRASFHLYTNTADVDALVEGLGQVRRFFLK

Sequences:

>Translated_441_residues
MTVVETRAAGAGAHAGAGFDVERVRRDFPILARTVHDGLPLVYLDSAATSQKPLAVLDAERTYYERHNANVHRGIHVLAE
EATALYEESRDKIAAFVGAPDRREIVFTKNSSEALNLVAYAMSNAVTGGPEAERFRLGPGDEVVITEMEHHSNLVPWQML
CARTGATLRWIGLTEDGRLDLAHLDEVITDRAKIVSFVHQSNILGTVNPVATIVARAREVGALTVLDGSQSVPHMPIDVV
DLGVDFLAFTGHKMCGPTGIGVLWGRRELLEVMPPFLGGGEMIEVVTMEASTYAAPPHRFEAGTPMISQAIGLGAAVDYL
TGLGMDAVAAHEHEITAYALDALAGVPGLRVIGPPTAEGRGGAISFALRDSEDRPLHPHDVGQILDEQGVAVRVGHHCAR
PVCLRYGVPATTRASFHLYTNTADVDALVEGLGQVRRFFLK
>Mature_440_residues
TVVETRAAGAGAHAGAGFDVERVRRDFPILARTVHDGLPLVYLDSAATSQKPLAVLDAERTYYERHNANVHRGIHVLAEE
ATALYEESRDKIAAFVGAPDRREIVFTKNSSEALNLVAYAMSNAVTGGPEAERFRLGPGDEVVITEMEHHSNLVPWQMLC
ARTGATLRWIGLTEDGRLDLAHLDEVITDRAKIVSFVHQSNILGTVNPVATIVARAREVGALTVLDGSQSVPHMPIDVVD
LGVDFLAFTGHKMCGPTGIGVLWGRRELLEVMPPFLGGGEMIEVVTMEASTYAAPPHRFEAGTPMISQAIGLGAAVDYLT
GLGMDAVAAHEHEITAYALDALAGVPGLRVIGPPTAEGRGGAISFALRDSEDRPLHPHDVGQILDEQGVAVRVGHHCARP
VCLRYGVPATTRASFHLYTNTADVDALVEGLGQVRRFFLK

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=228, Percent_Identity=30.7017543859649, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI156713448, Length=394, Percent_Identity=24.6192893401015, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1787970, Length=422, Percent_Identity=45.0236966824645, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1789175, Length=419, Percent_Identity=38.4248210023866, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI48994898, Length=283, Percent_Identity=29.6819787985866, Blast_Score=105, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI193211090, Length=350, Percent_Identity=28.5714285714286, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25143064, Length=253, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319831, Length=239, Percent_Identity=28.0334728033473, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI20129463, Length=341, Percent_Identity=29.0322580645161, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 47372; Mature: 47240

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVVETRAAGAGAHAGAGFDVERVRRDFPILARTVHDGLPLVYLDSAATSQKPLAVLDAE
CCEEECCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCEEEECCCCCCCCCEEEEECH
RTYYERHNANVHRGIHVLAEEATALYEESRDKIAAFVGAPDRREIVFTKNSSEALNLVAY
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEECCCCHHHHHHHH
AMSNAVTGGPEAERFRLGPGDEVVITEMEHHSNLVPWQMLCARTGATLRWIGLTEDGRLD
HHHCCCCCCCCCCEEECCCCCCEEEEEEHHCCCCCHHHHHHHCCCCEEEEEEECCCCCCC
LAHLDEVITDRAKIVSFVHQSNILGTVNPVATIVARAREVGALTVLDGSQSVPHMPIDVV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHH
DLGVDFLAFTGHKMCGPTGIGVLWGRRELLEVMPPFLGGGEMIEVVTMEASTYAAPPHRF
HHCHHHHHHCCCCCCCCCCCCHHHCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCC
EAGTPMISQAIGLGAAVDYLTGLGMDAVAAHEHEITAYALDALAGVPGLRVIGPPTAEGR
CCCCCHHHHHHCCHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCC
GGAISFALRDSEDRPLHPHDVGQILDEQGVAVRVGHHCARPVCLRYGVPATTRASFHLYT
CCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCCCEEEEEEE
NTADVDALVEGLGQVRRFFLK
CCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVVETRAAGAGAHAGAGFDVERVRRDFPILARTVHDGLPLVYLDSAATSQKPLAVLDAE
CEEECCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCEEEECCCCCCCCCEEEEECH
RTYYERHNANVHRGIHVLAEEATALYEESRDKIAAFVGAPDRREIVFTKNSSEALNLVAY
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEECCCCHHHHHHHH
AMSNAVTGGPEAERFRLGPGDEVVITEMEHHSNLVPWQMLCARTGATLRWIGLTEDGRLD
HHHCCCCCCCCCCEEECCCCCCEEEEEEHHCCCCCHHHHHHHCCCCEEEEEEECCCCCCC
LAHLDEVITDRAKIVSFVHQSNILGTVNPVATIVARAREVGALTVLDGSQSVPHMPIDVV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHH
DLGVDFLAFTGHKMCGPTGIGVLWGRRELLEVMPPFLGGGEMIEVVTMEASTYAAPPHRF
HHCHHHHHHCCCCCCCCCCCCHHHCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCC
EAGTPMISQAIGLGAAVDYLTGLGMDAVAAHEHEITAYALDALAGVPGLRVIGPPTAEGR
CCCCCHHHHHHCCHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCC
GGAISFALRDSEDRPLHPHDVGQILDEQGVAVRVGHHCARPVCLRYGVPATTRASFHLYT
CCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCCCEEEEEEE
NTADVDALVEGLGQVRRFFLK
CCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]