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The map label for this gene is ykoW [H]

Identifier: 158313879

GI number: 158313879

Start: 2458801

End: 2462361

Strand: Direct

Name: ykoW [H]

Synonym: Franean1_2044

Alternate gene names: 158313879

Gene position: 2458801-2462361 (Clockwise)

Preceding gene: 158313878

Following gene: 158313883

Centisome position: 27.37

GC content: 74.08

Gene sequence:

>3561_bases
GTGACCAGCGGTCCCGTAGTCGTCGACCGCCGCCGCCTGCTAGTGGTCCTCACCGTCGGGATGGTGGGGTTCTTCCTGTT
GGTCCTGACCGTCCCCGGATCCCCGGGGCGGCTGCGTGTCGGGACGTGGATCGCACTGGCCATCGCGCTGGTCAACCTGG
CCCTCATCCAGCGGCTCGTCACCGCCCACGAGCGGTGGCCGTGGCTGGCCGCGCTCGCCGCCGTCTCGATGGCGGCCGGG
ATGGGAGCCGCGGCCGCGGACGCCATACCCGGGGAGGAAAGCCAGCTGTTCCTGCTGTGGTTCCCCTGGATCGCCAGCTA
CTGCGGTGTGCTCAGGCTCGGCTGGAGCCTGGCCATGGCGGCCTGGGTGACCCTGACGCTGTTGCTGGCGGCGTCGGTCA
ACTCCGCTCTCGCCGGCTCGCCGGCGCTGCTGATCGCGGCGGCCGTCAGCTCGGCCGGCGGCTGCCTGGTGATGTACGTG
CTGTTCCAGTGGCGCGGGGAGCAGGCCTACTCCGATCCGCTGACGTCCCTGGTGGCACGCAGCGGGCTGACTCGCGCCGC
GGACCCGGCGATCGCACGGGCGGTCAAGAAGGACCGCGAGGCGGTCCTGCTCCTGCTCGACATCAACCGGTTCCGGGAGG
TCAACGACGCGCTGGGGCACGAGGCCGGTGACGAGCTGCTGCGCCAGCTGGCCCGCGCTCTTCCCACGGTGACGCCGCGG
CCGTCCTTCGTCGGCCGGCTCGGCAGCGACGAGTTCGCGCTCGTCATCCCCGGCCCGCCCGGCGCGGACCGGCGTGACGA
CGAGCTGGGCGGTGGTGATGCCAGCCGCGGAGATCCGGACCGCGGCGGGTCCGCACACGGCGGCCCGCACCGGGGCGGGT
CCGTGTCGACGTCGGCGAGTCGGGAGAGCGACCTGCGCGAGCTTGGCCAGTCGGTGCTGCGCCAGATCGAGGGGCCGTTC
ACCGTGCACGGCGTCGAGGTCGAGGTCGAGGCGAGCGCCGGGCTGGCGGTCGCCCCGCGTGACGGGGAGACGATCGGGTC
GTTGCTGCCCTGCGCGGACGCGGCGCTGTCCCGGGCTAAGCGCGAGGGCGAGCGGGTCGGGCTGTGGGACGCGGGCATCG
CGGGCGTGCGCTCCTGGGAGATCGCGCTGTACGCGGAGCTGCGCGCGGCTATCGCCAGGGACGAGCTCATCGTCTTCTAC
CAGCCGCTCCAGGCGGCGGCGACCGGGCGGATCGTCGGCGTCGAGGCTCTCGTGCGCTGGAGCCATCCGACCCGCGGGCT
GTTGCCGCCCGGCGCGTTCCTGCCGATGGCGGAGCGCTCGGCGCTCATCGTCGACGTCACGAGGTGGGTGCTGGACGAGG
CGCTGCGGCAGTGCGCCGCGTGGGCCGCCCGTGGGCTGCACGTGCCCGTCTCGGTGAACCTCTCCGCCCGCATGCTCGTC
CTGGACGACCTGCCCAGTCTGGTGACCGGGAGCCTTGCCCGCCACCAGCTCCCCCCGGACGTACTGACCCTTGAGATCAC
CGAGAGCGCCCTGGTGACCCAGCCCGGCCGGGCCGCCGCCATGCTCCGGGAGCTGCGCAGCAAGGGCGTCAAGCTCGCCC
TGGACGACTTCGGCACCGGTTACAGCTCGATGGAGATCCTCAAGGCGCTGCCGTTCGACGAGGTCAAGATCGACCGCGGG
TTCGTCGCGGACGTCCGCGGCAGCCTGCTGGACGCGGCGATCGTGCGTTCGGTGCTGGACCTCGGCCACCGGCTCGGCCT
GCGGGTCGTCGGCGAGGGCGTCGAGGACGACCGGACGCTGCGGATGATGACCGAGCTCGGCTGCGACATCCTGCAGGGCG
ACGCGGTCTCGCGCCCGCGCCCGCCGTCGCATCTCGAGGACCTGCTGGTGGAGCGGGCCGCACCCGCCGACCGCCCCGGC
GCCGCCGGTGCGGCGGTCCCTGCCGCCCTGCCGGCTGATGGCGCTGTGCCGGCTGGTGGTGCTGTGCCGGCCGGCAGCGG
CGCGCCGGTGGGCGGTGCCGGGCCGGCGGCCGACGCGGTGGACGCGGCGCGTTCCGAGCCGATCGTCGGCCCGGAGGCCC
CCTTCACGGTGTCGCAGACGCGGCGGTTCGGTGTCCTGGCCCCGCCGGTGGCGGACGAGGCGGCGCGGGTCGCCGCGACC
CGGCGCTACGAGATCGCGTTCCGGCCGCGGACCTACCCCCTGGACGACATGGCGGCCCTCGCGGCCGCGATGACCGGCTG
CAACGTGGGGTCGGTGCTCCTGGTCGGCGCCGACTCGGAGACCTACCTGGGCCGCCACGGCCACGACCTGAACGACGTGC
CGGCCCGGGTCGGCGTGGCCTCGCACGCCGTGGCGGCGGGCGAGCTGCTGGAGATTCCCGACGCGATGCTCGACACCCGG
TTCGCGCACGGGACCAGGGCGTTCCCCGGCCGGCAGATCCGTTTCATCGCAGCCGTCCCGGTGCGGACCTCCGACGGCCA
CGCCATCGGCGCGGTTACGATCAGCGACCGGATCCCGCGGCGGCTCACCCCGGGCCAGCGCGAGGCGCTGGAGAGCCTCG
CCCAGCACGCCGCGGTCATGATGGACGTCCGCCGGGAGGCCGTGCTGCTCGCCGTGGTCACCGACACCGCCCGGGCACTG
GACCAGCTCTGTTACCCGGATGATCTCCCGGCGGCCGCGTCCCTGGTCAGTGACGCCGCGCGGCACATGCTGGGCGGCGA
CGTCGTCACCGTCCTGATGTCCGACACGCCCGGCTCGACGGTCTACAGCTCCGTAGGGGCTTCCCTCGCGCCCGGGGCCA
CCTCCCTCATCAAGCCGGGGCAGCGGTTCAACTCGAACGACGAGACGGTCATCGGTGAGGTCCTGCGGACACAGAGCCCG
CTGTTCGTCCCGGACGCGCCGACCTTCCCCGGCTTCAACCTGGACATCGTCCGTGCCAGCGGCGTGGCTTCTGCGTTCCT
CGTCCCGATCCCGGGGGAGGGCGGTGCGCTCGGCGTCATGTGCGCCCGCTGGCCGGCCCCGGTGGCCGCGATCGACCCGT
CGTTGTACCGCGCGATGGCGCTGCTGGTCGGGCAGGTGGGGCACGGCCTCGGCCGGCTGCGGGCCGCCTCGGATCGGGAG
CACCACCCGGACGGTACGGCCGGGCTGACCGGCCGGGCGGCCTTCCTCTCCACCTTGCAGGGGCTGTCGCCGGGCGCCGG
CGTGTGCCTGTTCGACGTCCAGGCGGGCCGGGACAGGTTGACCAGGCGGTTCGCCGAGCTCCTGCGGGCCGTCTGCGACG
AGTCCGCGTATCTCGCCCGCTGGTCGGACAGCCGGTTCGCGGTGGCCGTCCCGACCGGCGGGCGGGAACGGGCCGAGGCG
ATGGTCGACGAGGTCCGCCGCTCGTGGGCCCGGGAGTCGGCGGTGCCGATCGCCGTCGGCATCTCGGTGACCAGGAGCCA
CGAGCCGTCGAGCGCCGCGCTCATCGACGCGGAGAACCGCCTGCTGGAGACGATGGCGGTGGTGATCCGGGCCGAGCGGG
CAGCCGCGGCGCGCGTGACAGCAACGTCAGCAGGGGTCTGA

Upstream 100 bases:

>100_bases
TCCGGCGCGCCCGGGCCCCGTCGGCCACTGGCCGCCACAACGGCGCCGGTCAGCGCCCAGCGCCGGGGATCTGCCGCGGC
CAGGGAGAGGGGGACGGGTC

Downstream 100 bases:

>100_bases
CCCCTTCGGGCACCGGCTCGTGGAACGTCCGCTCCACCCGCCCGCCCTGGAACTCCACCTCGATCACGTAGACGAAGCGA
TCCGCCCCCGCCGGGCCGCC

Product: GAF sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1186; Mature: 1185

Protein sequence:

>1186_residues
MTSGPVVVDRRRLLVVLTVGMVGFFLLVLTVPGSPGRLRVGTWIALAIALVNLALIQRLVTAHERWPWLAALAAVSMAAG
MGAAAADAIPGEESQLFLLWFPWIASYCGVLRLGWSLAMAAWVTLTLLLAASVNSALAGSPALLIAAAVSSAGGCLVMYV
LFQWRGEQAYSDPLTSLVARSGLTRAADPAIARAVKKDREAVLLLLDINRFREVNDALGHEAGDELLRQLARALPTVTPR
PSFVGRLGSDEFALVIPGPPGADRRDDELGGGDASRGDPDRGGSAHGGPHRGGSVSTSASRESDLRELGQSVLRQIEGPF
TVHGVEVEVEASAGLAVAPRDGETIGSLLPCADAALSRAKREGERVGLWDAGIAGVRSWEIALYAELRAAIARDELIVFY
QPLQAAATGRIVGVEALVRWSHPTRGLLPPGAFLPMAERSALIVDVTRWVLDEALRQCAAWAARGLHVPVSVNLSARMLV
LDDLPSLVTGSLARHQLPPDVLTLEITESALVTQPGRAAAMLRELRSKGVKLALDDFGTGYSSMEILKALPFDEVKIDRG
FVADVRGSLLDAAIVRSVLDLGHRLGLRVVGEGVEDDRTLRMMTELGCDILQGDAVSRPRPPSHLEDLLVERAAPADRPG
AAGAAVPAALPADGAVPAGGAVPAGSGAPVGGAGPAADAVDAARSEPIVGPEAPFTVSQTRRFGVLAPPVADEAARVAAT
RRYEIAFRPRTYPLDDMAALAAAMTGCNVGSVLLVGADSETYLGRHGHDLNDVPARVGVASHAVAAGELLEIPDAMLDTR
FAHGTRAFPGRQIRFIAAVPVRTSDGHAIGAVTISDRIPRRLTPGQREALESLAQHAAVMMDVRREAVLLAVVTDTARAL
DQLCYPDDLPAAASLVSDAARHMLGGDVVTVLMSDTPGSTVYSSVGASLAPGATSLIKPGQRFNSNDETVIGEVLRTQSP
LFVPDAPTFPGFNLDIVRASGVASAFLVPIPGEGGALGVMCARWPAPVAAIDPSLYRAMALLVGQVGHGLGRLRAASDRE
HHPDGTAGLTGRAAFLSTLQGLSPGAGVCLFDVQAGRDRLTRRFAELLRAVCDESAYLARWSDSRFAVAVPTGGRERAEA
MVDEVRRSWARESAVPIAVGISVTRSHEPSSAALIDAENRLLETMAVVIRAERAAAARVTATSAGV

Sequences:

>Translated_1186_residues
MTSGPVVVDRRRLLVVLTVGMVGFFLLVLTVPGSPGRLRVGTWIALAIALVNLALIQRLVTAHERWPWLAALAAVSMAAG
MGAAAADAIPGEESQLFLLWFPWIASYCGVLRLGWSLAMAAWVTLTLLLAASVNSALAGSPALLIAAAVSSAGGCLVMYV
LFQWRGEQAYSDPLTSLVARSGLTRAADPAIARAVKKDREAVLLLLDINRFREVNDALGHEAGDELLRQLARALPTVTPR
PSFVGRLGSDEFALVIPGPPGADRRDDELGGGDASRGDPDRGGSAHGGPHRGGSVSTSASRESDLRELGQSVLRQIEGPF
TVHGVEVEVEASAGLAVAPRDGETIGSLLPCADAALSRAKREGERVGLWDAGIAGVRSWEIALYAELRAAIARDELIVFY
QPLQAAATGRIVGVEALVRWSHPTRGLLPPGAFLPMAERSALIVDVTRWVLDEALRQCAAWAARGLHVPVSVNLSARMLV
LDDLPSLVTGSLARHQLPPDVLTLEITESALVTQPGRAAAMLRELRSKGVKLALDDFGTGYSSMEILKALPFDEVKIDRG
FVADVRGSLLDAAIVRSVLDLGHRLGLRVVGEGVEDDRTLRMMTELGCDILQGDAVSRPRPPSHLEDLLVERAAPADRPG
AAGAAVPAALPADGAVPAGGAVPAGSGAPVGGAGPAADAVDAARSEPIVGPEAPFTVSQTRRFGVLAPPVADEAARVAAT
RRYEIAFRPRTYPLDDMAALAAAMTGCNVGSVLLVGADSETYLGRHGHDLNDVPARVGVASHAVAAGELLEIPDAMLDTR
FAHGTRAFPGRQIRFIAAVPVRTSDGHAIGAVTISDRIPRRLTPGQREALESLAQHAAVMMDVRREAVLLAVVTDTARAL
DQLCYPDDLPAAASLVSDAARHMLGGDVVTVLMSDTPGSTVYSSVGASLAPGATSLIKPGQRFNSNDETVIGEVLRTQSP
LFVPDAPTFPGFNLDIVRASGVASAFLVPIPGEGGALGVMCARWPAPVAAIDPSLYRAMALLVGQVGHGLGRLRAASDRE
HHPDGTAGLTGRAAFLSTLQGLSPGAGVCLFDVQAGRDRLTRRFAELLRAVCDESAYLARWSDSRFAVAVPTGGRERAEA
MVDEVRRSWARESAVPIAVGISVTRSHEPSSAALIDAENRLLETMAVVIRAERAAAARVTATSAGV
>Mature_1185_residues
TSGPVVVDRRRLLVVLTVGMVGFFLLVLTVPGSPGRLRVGTWIALAIALVNLALIQRLVTAHERWPWLAALAAVSMAAGM
GAAAADAIPGEESQLFLLWFPWIASYCGVLRLGWSLAMAAWVTLTLLLAASVNSALAGSPALLIAAAVSSAGGCLVMYVL
FQWRGEQAYSDPLTSLVARSGLTRAADPAIARAVKKDREAVLLLLDINRFREVNDALGHEAGDELLRQLARALPTVTPRP
SFVGRLGSDEFALVIPGPPGADRRDDELGGGDASRGDPDRGGSAHGGPHRGGSVSTSASRESDLRELGQSVLRQIEGPFT
VHGVEVEVEASAGLAVAPRDGETIGSLLPCADAALSRAKREGERVGLWDAGIAGVRSWEIALYAELRAAIARDELIVFYQ
PLQAAATGRIVGVEALVRWSHPTRGLLPPGAFLPMAERSALIVDVTRWVLDEALRQCAAWAARGLHVPVSVNLSARMLVL
DDLPSLVTGSLARHQLPPDVLTLEITESALVTQPGRAAAMLRELRSKGVKLALDDFGTGYSSMEILKALPFDEVKIDRGF
VADVRGSLLDAAIVRSVLDLGHRLGLRVVGEGVEDDRTLRMMTELGCDILQGDAVSRPRPPSHLEDLLVERAAPADRPGA
AGAAVPAALPADGAVPAGGAVPAGSGAPVGGAGPAADAVDAARSEPIVGPEAPFTVSQTRRFGVLAPPVADEAARVAATR
RYEIAFRPRTYPLDDMAALAAAMTGCNVGSVLLVGADSETYLGRHGHDLNDVPARVGVASHAVAAGELLEIPDAMLDTRF
AHGTRAFPGRQIRFIAAVPVRTSDGHAIGAVTISDRIPRRLTPGQREALESLAQHAAVMMDVRREAVLLAVVTDTARALD
QLCYPDDLPAAASLVSDAARHMLGGDVVTVLMSDTPGSTVYSSVGASLAPGATSLIKPGQRFNSNDETVIGEVLRTQSPL
FVPDAPTFPGFNLDIVRASGVASAFLVPIPGEGGALGVMCARWPAPVAAIDPSLYRAMALLVGQVGHGLGRLRAASDREH
HPDGTAGLTGRAAFLSTLQGLSPGAGVCLFDVQAGRDRLTRRFAELLRAVCDESAYLARWSDSRFAVAVPTGGRERAEAM
VDEVRRSWARESAVPIAVGISVTRSHEPSSAALIDAENRLLETMAVVIRAERAAAARVTATSAGV

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=459, Percent_Identity=29.6296296296296, Blast_Score=210, Evalue=5e-55,
Organism=Escherichia coli, GI87081921, Length=452, Percent_Identity=27.8761061946903, Blast_Score=183, Evalue=6e-47,
Organism=Escherichia coli, GI226510982, Length=328, Percent_Identity=30.7926829268293, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI87081980, Length=248, Percent_Identity=35.8870967741936, Blast_Score=139, Evalue=1e-33,
Organism=Escherichia coli, GI1790496, Length=238, Percent_Identity=29.4117647058824, Blast_Score=136, Evalue=7e-33,
Organism=Escherichia coli, GI87081845, Length=240, Percent_Identity=35, Blast_Score=133, Evalue=6e-32,
Organism=Escherichia coli, GI1788502, Length=242, Percent_Identity=35.1239669421488, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI87081743, Length=246, Percent_Identity=30.0813008130081, Blast_Score=126, Evalue=8e-30,
Organism=Escherichia coli, GI1786507, Length=236, Percent_Identity=32.6271186440678, Blast_Score=125, Evalue=2e-29,
Organism=Escherichia coli, GI1788849, Length=242, Percent_Identity=30.1652892561983, Blast_Score=113, Evalue=6e-26,
Organism=Escherichia coli, GI1787055, Length=292, Percent_Identity=27.0547945205479, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI87082096, Length=249, Percent_Identity=29.718875502008, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI87081881, Length=111, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1787410, Length=152, Percent_Identity=24.3421052631579, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 124322; Mature: 124191

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGPVVVDRRRLLVVLTVGMVGFFLLVLTVPGSPGRLRVGTWIALAIALVNLALIQRLV
CCCCCEEECCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
TAHERWPWLAALAAVSMAAGMGAAAADAIPGEESQLFLLWFPWIASYCGVLRLGWSLAMA
HHHHCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
AWVTLTLLLAASVNSALAGSPALLIAAAVSSAGGCLVMYVLFQWRGEQAYSDPLTSLVAR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
SGLTRAADPAIARAVKKDREAVLLLLDINRFREVNDALGHEAGDELLRQLARALPTVTPR
CCCCCCCCHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
PSFVGRLGSDEFALVIPGPPGADRRDDELGGGDASRGDPDRGGSAHGGPHRGGSVSTSAS
CHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
RESDLRELGQSVLRQIEGPFTVHGVEVEVEASAGLAVAPRDGETIGSLLPCADAALSRAK
HHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHH
REGERVGLWDAGIAGVRSWEIALYAELRAAIARDELIVFYQPLQAAATGRIVGVEALVRW
HCCCEECEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCEEEHHHHHCC
SHPTRGLLPPGAFLPMAERSALIVDVTRWVLDEALRQCAAWAARGLHVPVSVNLSARMLV
CCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEE
LDDLPSLVTGSLARHQLPPDVLTLEITESALVTQPGRAAAMLRELRSKGVKLALDDFGTG
ECCCHHHHHHHHHHHCCCCCEEEEEEECHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCC
YSSMEILKALPFDEVKIDRGFVADVRGSLLDAAIVRSVLDLGHRLGLRVVGEGVEDDRTL
HHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHH
RMMTELGCDILQGDAVSRPRPPSHLEDLLVERAAPADRPGAAGAAVPAALPADGAVPAGG
HHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AVPAGSGAPVGGAGPAADAVDAARSEPIVGPEAPFTVSQTRRFGVLAPPVADEAARVAAT
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHCCCCCCEECCCCHHHHHHHHHH
RRYEIAFRPRTYPLDDMAALAAAMTGCNVGSVLLVGADSETYLGRHGHDLNDVPARVGVA
EEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHH
SHAVAAGELLEIPDAMLDTRFAHGTRAFPGRQIRFIAAVPVRTSDGHAIGAVTISDRIPR
HHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEEECCCCCC
RLTPGQREALESLAQHAAVMMDVRREAVLLAVVTDTARALDQLCYPDDLPAAASLVSDAA
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHH
RHMLGGDVVTVLMSDTPGSTVYSSVGASLAPGATSLIKPGQRFNSNDETVIGEVLRTQSP
HHHHCCCEEEEEECCCCCCHHHHHCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCC
LFVPDAPTFPGFNLDIVRASGVASAFLVPIPGEGGALGVMCARWPAPVAAIDPSLYRAMA
EECCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEECCCCCHHHCCHHHHHHHH
LLVGQVGHGLGRLRAASDREHHPDGTAGLTGRAAFLSTLQGLSPGAGVCLFDVQAGRDRL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHHH
TRRFAELLRAVCDESAYLARWSDSRFAVAVPTGGRERAEAMVDEVRRSWARESAVPIAVG
HHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEE
ISVTRSHEPSSAALIDAENRLLETMAVVIRAERAAAARVTATSAGV
EEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
TSGPVVVDRRRLLVVLTVGMVGFFLLVLTVPGSPGRLRVGTWIALAIALVNLALIQRLV
CCCCEEECCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
TAHERWPWLAALAAVSMAAGMGAAAADAIPGEESQLFLLWFPWIASYCGVLRLGWSLAMA
HHHHCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
AWVTLTLLLAASVNSALAGSPALLIAAAVSSAGGCLVMYVLFQWRGEQAYSDPLTSLVAR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
SGLTRAADPAIARAVKKDREAVLLLLDINRFREVNDALGHEAGDELLRQLARALPTVTPR
CCCCCCCCHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
PSFVGRLGSDEFALVIPGPPGADRRDDELGGGDASRGDPDRGGSAHGGPHRGGSVSTSAS
CHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
RESDLRELGQSVLRQIEGPFTVHGVEVEVEASAGLAVAPRDGETIGSLLPCADAALSRAK
HHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHH
REGERVGLWDAGIAGVRSWEIALYAELRAAIARDELIVFYQPLQAAATGRIVGVEALVRW
HCCCEECEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCEEEHHHHHCC
SHPTRGLLPPGAFLPMAERSALIVDVTRWVLDEALRQCAAWAARGLHVPVSVNLSARMLV
CCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEE
LDDLPSLVTGSLARHQLPPDVLTLEITESALVTQPGRAAAMLRELRSKGVKLALDDFGTG
ECCCHHHHHHHHHHHCCCCCEEEEEEECHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCC
YSSMEILKALPFDEVKIDRGFVADVRGSLLDAAIVRSVLDLGHRLGLRVVGEGVEDDRTL
HHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHH
RMMTELGCDILQGDAVSRPRPPSHLEDLLVERAAPADRPGAAGAAVPAALPADGAVPAGG
HHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AVPAGSGAPVGGAGPAADAVDAARSEPIVGPEAPFTVSQTRRFGVLAPPVADEAARVAAT
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHCCCCCCEECCCCHHHHHHHHHH
RRYEIAFRPRTYPLDDMAALAAAMTGCNVGSVLLVGADSETYLGRHGHDLNDVPARVGVA
EEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHH
SHAVAAGELLEIPDAMLDTRFAHGTRAFPGRQIRFIAAVPVRTSDGHAIGAVTISDRIPR
HHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEEECCCCCC
RLTPGQREALESLAQHAAVMMDVRREAVLLAVVTDTARALDQLCYPDDLPAAASLVSDAA
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHH
RHMLGGDVVTVLMSDTPGSTVYSSVGASLAPGATSLIKPGQRFNSNDETVIGEVLRTQSP
HHHHCCCEEEEEECCCCCCHHHHHCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCC
LFVPDAPTFPGFNLDIVRASGVASAFLVPIPGEGGALGVMCARWPAPVAAIDPSLYRAMA
EECCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEECCCCCHHHCCHHHHHHHH
LLVGQVGHGLGRLRAASDREHHPDGTAGLTGRAAFLSTLQGLSPGAGVCLFDVQAGRDRL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHHH
TRRFAELLRAVCDESAYLARWSDSRFAVAVPTGGRERAEAMVDEVRRSWARESAVPIAVG
HHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEE
ISVTRSHEPSSAALIDAENRLLETMAVVIRAERAAAARVTATSAGV
EEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]