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The map label for this gene is coaE [H]

Identifier: 158313883

GI number: 158313883

Start: 2466207

End: 2466827

Strand: Direct

Name: coaE [H]

Synonym: Franean1_2048

Alternate gene names: 158313883

Gene position: 2466207-2466827 (Clockwise)

Preceding gene: 158313879

Following gene: 158313884

Centisome position: 27.46

GC content: 75.52

Gene sequence:

>621_bases
GTGGGCCTCACGGGCGGAATCGGGTCGGGCAAGAGCGCCGTGTCGGAACTCCTGGTGGAACACGGCGCCCATCTGGTGGA
CGCCGACCGGATCGCCCGCGAGGTAGTCGCCCCCGGGACGCCAGGCCTCGCCGCCGTCGCCGAGGCGTTCGGGCCGTCCG
TGCTGCTGGCGGACGGCGCCCTCGACCGGGAGGCGCTGGGGCGCGTGGTGTTCGCCGACGAGGCGAGCCGGCGGCGGCTC
GAGTCGATCACCCATCCGCTGATCCGGGCGGAGATGGCGGCCCGGATCGCGTCCGCGCCGCCGGACGCCGTCGTGATCCA
CGACATCCCGCTGCTGGTCGAGGGCGGACCGCGCCCCGGCTACGACGCGATCGTGGTCGTCGAGACACCACGCGAGCTGC
GTCTGGAGCGGCTCGCCCGGCGAGGTCTCGCCCGGGACCAGGCCGAGGCCCGGATGGCCGCCCAGGCCACCGACGAACAG
CGGCGGGCGGTCGCCGACATCCTGGTCGACAACAGCGGGTCGCTCGACGACCTACGGAAACGCGTGGGCGAGGTGTGGGG
GGAGCTGCTGCGCCGGCGTGACGCCGGGCTGGCCGAGCCCTCCGCCCGCCCCGGCTCCTGA

Upstream 100 bases:

>100_bases
GGCGCCACCCGTCCAGTGTGCCAACCCGCGCGGCCGGCCGGCGCCGCGCGGACCCGTCGCGGGCACGGGAGGCTCCTGGC
AGACTCGGCTGGTGCTGATT

Downstream 100 bases:

>100_bases
GCGCCGTGGCCTGGGAGTGGGACGCGGCCGCCTACGGCCGGCTGCGGCTGCCGCACGAGCTGTGGGGGCAGCGCACGCTT
GCCCGGCTCGCGCTGACCGG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MGLTGGIGSGKSAVSELLVEHGAHLVDADRIAREVVAPGTPGLAAVAEAFGPSVLLADGALDREALGRVVFADEASRRRL
ESITHPLIRAEMAARIASAPPDAVVIHDIPLLVEGGPRPGYDAIVVVETPRELRLERLARRGLARDQAEARMAAQATDEQ
RRAVADILVDNSGSLDDLRKRVGEVWGELLRRRDAGLAEPSARPGS

Sequences:

>Translated_206_residues
MGLTGGIGSGKSAVSELLVEHGAHLVDADRIAREVVAPGTPGLAAVAEAFGPSVLLADGALDREALGRVVFADEASRRRL
ESITHPLIRAEMAARIASAPPDAVVIHDIPLLVEGGPRPGYDAIVVVETPRELRLERLARRGLARDQAEARMAAQATDEQ
RRAVADILVDNSGSLDDLRKRVGEVWGELLRRRDAGLAEPSARPGS
>Mature_205_residues
GLTGGIGSGKSAVSELLVEHGAHLVDADRIAREVVAPGTPGLAAVAEAFGPSVLLADGALDREALGRVVFADEASRRRLE
SITHPLIRAEMAARIASAPPDAVVIHDIPLLVEGGPRPGYDAIVVVETPRELRLERLARRGLARDQAEARMAAQATDEQR
RAVADILVDNSGSLDDLRKRVGEVWGELLRRRDAGLAEPSARPGS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=197, Percent_Identity=40.6091370558376, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI191252795, Length=197, Percent_Identity=40.6091370558376, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI110227607, Length=197, Percent_Identity=28.9340101522843, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI110227605, Length=197, Percent_Identity=28.9340101522843, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI110227603, Length=197, Percent_Identity=28.9340101522843, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI110227601, Length=197, Percent_Identity=28.9340101522843, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI205277394, Length=197, Percent_Identity=28.9340101522843, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1786292, Length=192, Percent_Identity=39.5833333333333, Blast_Score=122, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17554944, Length=194, Percent_Identity=35.5670103092784, Blast_Score=127, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25143409, Length=194, Percent_Identity=27.8350515463918, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=193, Percent_Identity=38.3419689119171, Blast_Score=118, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24644728, Length=181, Percent_Identity=34.2541436464088, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24658602, Length=200, Percent_Identity=29.5, Blast_Score=91, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21805; Mature: 21674

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTGGIGSGKSAVSELLVEHGAHLVDADRIAREVVAPGTPGLAAVAEAFGPSVLLADGA
CCCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCHHHHHHHHHCCCEEEECCC
LDREALGRVVFADEASRRRLESITHPLIRAEMAARIASAPPDAVVIHDIPLLVEGGPRPG
CCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCC
YDAIVVVETPRELRLERLARRGLARDQAEARMAAQATDEQRRAVADILVDNSGSLDDLRK
CCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
RVGEVWGELLRRRDAGLAEPSARPGS
HHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GLTGGIGSGKSAVSELLVEHGAHLVDADRIAREVVAPGTPGLAAVAEAFGPSVLLADGA
CCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCHHHHHHHHHCCCEEEECCC
LDREALGRVVFADEASRRRLESITHPLIRAEMAARIASAPPDAVVIHDIPLLVEGGPRPG
CCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCC
YDAIVVVETPRELRLERLARRGLARDQAEARMAAQATDEQRRAVADILVDNSGSLDDLRK
CCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
RVGEVWGELLRRRDAGLAEPSARPGS
HHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA