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The map label for this gene is livK [C]

Identifier: 158313872

GI number: 158313872

Start: 2449126

End: 2450337

Strand: Direct

Name: livK [C]

Synonym: Franean1_2037

Alternate gene names: 158313872

Gene position: 2449126-2450337 (Clockwise)

Preceding gene: 158313871

Following gene: 158313873

Centisome position: 27.27

GC content: 70.54

Gene sequence:

>1212_bases
ATGACGGGCAGCCCACGCACCCCTCGACCCAGGACCAGACGGGCCGGGGTCCTGCGGCCGGTCGCCGGGGTGGTCGCGGG
CCTGGCGATGGTCGGCGCGGCGTTGACCGCCTGCGGCGGTGGTGACTCGAACGAGGCCGGTACCAAGGAGTTCCTCATCG
GCTTCCAGGGACCGCTGTCCGGGGAGAACCAGCAGCTCGGCATCAACGCCTACAACGGCGTGCTGACCGCCGTCGACCTG
GCCAACCGCACCGGCGGCCTGCCGTTCACCCTGCGGATCGTCGCCTCCGACGACCAGGGCGTGCCCGAGCAGGGGCCGAC
CGCCGCCCAGAAGCTCATCGACAACCCGGACGTCGTCGCGGTCGTCGGCCCGGTGTTCTCCGCGCCGACGAAGGCCAGCG
AGCCGCTGTACAGCCAGACAGGCCTGCTGTCGGTCAGCCCGTCGGCGACCGCCCCGGCGCTCACCGACCTCGGGTTCACC
AGCTTCTACCGGGTGATCGCACCGGACACCGTGCAGGGCGCCGGCGCCGCCGAGTACCTCGCCAAGGTCGTGAAGGCCAA
GCGCGTCTACTCGCTGGACGACCGCAGCGAGTACGGCACCGGCCTCTCCGGCGCCGTCGAGCGCGGCCTGAAGCAGGCGG
GCGTCGCCTACACCCACGACGGGATCAACCCGACGAAGGACTACACCTCCCAGGCGACGAAGATCATGGCGGACGGCGCC
GACGCCGTCTACTACTCCGGGTACTACTCCGACTTCGCGCTCCTCACGAAGGCGCTGCGCAGCAAGGGGTACGACGGGGC
GATCCTCAGCGGCGACGGCTCGAACGACGACCAGTACATCCGCCAGGCCGGCGCGGCGAACGCCGAGGGCACGCTCATCA
CCTGCCCCTGCTCGGACGCCAACACCGACCCGGCCGCCACCGGCTTCGTCAGCGAGTACAAGAAGGTCAACAGCGGCCTG
AAGCCGGGCACGTACTCCGGCGAGGCCTACGACGCCACCAACGCCATCATCTCGGTGCTGCGCAAGCTCGGGACCGGCGC
CAGCCGCGAGTCGGTGCTCGCCGACTTCGGCTCGGTCGACTTCCCCGGGGTGACCAAGCGGATCCGCTTCGAGCGCAACG
GTGACGTCCAGGGCTCGACCGTCTACGTGTACCAGGTGAAGGACGGCCAGCGCGTGGTGCTCGGGCCGGTCAGCTCGCTC
GTCAAGCCGTGA

Upstream 100 bases:

>100_bases
ACACTCTTACTTTCAGCTTTCATCGCTCGGGTGGAGCCGCTAGGTTTCCGCTGCGCGGAGCGCGCCCGCGCGCCGGTGGA
AAGCAGCGGAAGGACGTGGC

Downstream 100 bases:

>100_bases
CCGGCCGGCGATCACCTTCCCGGCGGGGCCGGGCCCGGCGGGTTCGGAGCCCGCGGGGCCTGGTCCGGCCGGAGCCGCGG
CGGAGGGTGGGGCATGGGCT

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTGSPRTPRPRTRRAGVLRPVAGVVAGLAMVGAALTACGGGDSNEAGTKEFLIGFQGPLSGENQQLGINAYNGVLTAVDL
ANRTGGLPFTLRIVASDDQGVPEQGPTAAQKLIDNPDVVAVVGPVFSAPTKASEPLYSQTGLLSVSPSATAPALTDLGFT
SFYRVIAPDTVQGAGAAEYLAKVVKAKRVYSLDDRSEYGTGLSGAVERGLKQAGVAYTHDGINPTKDYTSQATKIMADGA
DAVYYSGYYSDFALLTKALRSKGYDGAILSGDGSNDDQYIRQAGAANAEGTLITCPCSDANTDPAATGFVSEYKKVNSGL
KPGTYSGEAYDATNAIISVLRKLGTGASRESVLADFGSVDFPGVTKRIRFERNGDVQGSTVYVYQVKDGQRVVLGPVSSL
VKP

Sequences:

>Translated_403_residues
MTGSPRTPRPRTRRAGVLRPVAGVVAGLAMVGAALTACGGGDSNEAGTKEFLIGFQGPLSGENQQLGINAYNGVLTAVDL
ANRTGGLPFTLRIVASDDQGVPEQGPTAAQKLIDNPDVVAVVGPVFSAPTKASEPLYSQTGLLSVSPSATAPALTDLGFT
SFYRVIAPDTVQGAGAAEYLAKVVKAKRVYSLDDRSEYGTGLSGAVERGLKQAGVAYTHDGINPTKDYTSQATKIMADGA
DAVYYSGYYSDFALLTKALRSKGYDGAILSGDGSNDDQYIRQAGAANAEGTLITCPCSDANTDPAATGFVSEYKKVNSGL
KPGTYSGEAYDATNAIISVLRKLGTGASRESVLADFGSVDFPGVTKRIRFERNGDVQGSTVYVYQVKDGQRVVLGPVSSL
VKP
>Mature_402_residues
TGSPRTPRPRTRRAGVLRPVAGVVAGLAMVGAALTACGGGDSNEAGTKEFLIGFQGPLSGENQQLGINAYNGVLTAVDLA
NRTGGLPFTLRIVASDDQGVPEQGPTAAQKLIDNPDVVAVVGPVFSAPTKASEPLYSQTGLLSVSPSATAPALTDLGFTS
FYRVIAPDTVQGAGAAEYLAKVVKAKRVYSLDDRSEYGTGLSGAVERGLKQAGVAYTHDGINPTKDYTSQATKIMADGAD
AVYYSGYYSDFALLTKALRSKGYDGAILSGDGSNDDQYIRQAGAANAEGTLITCPCSDANTDPAATGFVSEYKKVNSGLK
PGTYSGEAYDATNAIISVLRKLGTGASRESVLADFGSVDFPGVTKRIRFERNGDVQGSTVYVYQVKDGQRVVLGPVSSLV
KP

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=346, Percent_Identity=28.9017341040462, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI48994941, Length=258, Percent_Identity=32.1705426356589, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 41808; Mature: 41677

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSPRTPRPRTRRAGVLRPVAGVVAGLAMVGAALTACGGGDSNEAGTKEFLIGFQGPLS
CCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
GENQQLGINAYNGVLTAVDLANRTGGLPFTLRIVASDDQGVPEQGPTAAQKLIDNPDVVA
CCCCEECEEHHCCCEEEEEHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCEEE
VVGPVFSAPTKASEPLYSQTGLLSVSPSATAPALTDLGFTSFYRVIAPDTVQGAGAAEYL
EECCHHCCCCCCCCCCHHCCCEEEECCCCCCCHHHHCCHHHHHHHHCCCCCCCCCHHHHH
AKVVKAKRVYSLDDRSEYGTGLSGAVERGLKQAGVAYTHDGINPTKDYTSQATKIMADGA
HHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCC
DAVYYSGYYSDFALLTKALRSKGYDGAILSGDGSNDDQYIRQAGAANAEGTLITCPCSDA
CEEEECCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCEEEECCCCC
NTDPAATGFVSEYKKVNSGLKPGTYSGEAYDATNAIISVLRKLGTGASRESVLADFGSVD
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCC
FPGVTKRIRFERNGDVQGSTVYVYQVKDGQRVVLGPVSSLVKP
CCCCCCEEEECCCCCCCCCEEEEEEECCCCEEEEECHHHHCCC
>Mature Secondary Structure 
TGSPRTPRPRTRRAGVLRPVAGVVAGLAMVGAALTACGGGDSNEAGTKEFLIGFQGPLS
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
GENQQLGINAYNGVLTAVDLANRTGGLPFTLRIVASDDQGVPEQGPTAAQKLIDNPDVVA
CCCCEECEEHHCCCEEEEEHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCEEE
VVGPVFSAPTKASEPLYSQTGLLSVSPSATAPALTDLGFTSFYRVIAPDTVQGAGAAEYL
EECCHHCCCCCCCCCCHHCCCEEEECCCCCCCHHHHCCHHHHHHHHCCCCCCCCCHHHHH
AKVVKAKRVYSLDDRSEYGTGLSGAVERGLKQAGVAYTHDGINPTKDYTSQATKIMADGA
HHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCC
DAVYYSGYYSDFALLTKALRSKGYDGAILSGDGSNDDQYIRQAGAANAEGTLITCPCSDA
CEEEECCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCEEEECCCCC
NTDPAATGFVSEYKKVNSGLKPGTYSGEAYDATNAIISVLRKLGTGASRESVLADFGSVD
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCC
FPGVTKRIRFERNGDVQGSTVYVYQVKDGQRVVLGPVSSLVKP
CCCCCCEEEECCCCCCCCCEEEEEEECCCCEEEEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]