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The map label for this gene is pheS [H]

Identifier: 158313569

GI number: 158313569

Start: 2069740

End: 2070843

Strand: Direct

Name: pheS [H]

Synonym: Franean1_1733

Alternate gene names: 158313569

Gene position: 2069740-2070843 (Clockwise)

Preceding gene: 158313568

Following gene: 158313570

Centisome position: 23.04

GC content: 74.0

Gene sequence:

>1104_bases
GTGCCCGCCCCCAACGAGACCGCTGATCCCGTGGATCTCGGTGCCCTGGATCCCGGACGGCTCGACGGCGCCGCGGCCGC
TGCACTCGCCGCGATCGCCGGGGCCGACGACCTGGCCGCGCTGTCCGCCGTGCGCACCGCCCACGTGGACGGACAGCAGG
CGCCGCTGATGCTCGCCCGTCGCGAGCTCGGAGCCCTGCCCCGCGAGCACCGGGCGGAGGCCGGCCGCGCGCACAACGCC
GCGACTGCGAAGGTCCGGGCCGCCTACGAGGCCCGGCTGGTCGAGCTCACCGCCCGGCGTGACGCCGAGATCCTGGTCGC
CGAGCGGGTCGACGTGACCCTGCCGGTCGACCGCCGCCGCCGCGGCGCCCGCCACCCGCTGAGCCTGCTCTCCGACCGGC
TCACCGACGTCTTCGTGGCCATGGGCTACGAGGTCGCCGAGGGCCCCGAGGTGGAGCACGACTGGTTCAACTTCGAGGCG
CTCAACATGGCGCCCGACCACCCCGCGCGCAGCGAGCACGACACGCTCTACGTCGAGCCGGCCGCGTCCGGCCGGCTGCT
GCGCACGCACACCTCGCCGGTGCAGATCCGCTCGCTGCTGTCCCGCCCGCTGCCGGTCTACGTGGTCTGCCCCGGGCGCA
CCTACCGCAACGACACGATCGACGCGACGCACTCGCCGGTGTTCGGCCAGCTCGAGTGCCTCGCCGTCGACGAAGGCATC
ACCATGGCCGACCTGCGCGGCACCCTCGAGGTGTTCGCCCAGGCGCTGTTCGGTTCCGGACTGTCCACCCGGCTGCGGCC
GTCGTTCTTCCCGTTCACCGAGCCGTCCGCCGAGCTGGACGTCCAGTGCTTCGCCTGCCGTGGCGACGCCGCCCGTCAGC
CGTGCCGGGTCTGCTCCGACGAGGGCTGGATCGAGGCCGGCGGCTGCGGGATGGTCGACCCGAACGTGCTGCGGGCCTGC
GGGGTCGACCCTGCGCGCTACAGCGGTTTCGCCTTCGGGATGGGCCTGGAACGGGCCGCGATGACCCGGCACGACGTCCG
CGAGATCCGCGACTTCGTCGACGGGGACGTCCGCTTCGGCCTGCCGTTCGGAAGCGAGGGCTGA

Upstream 100 bases:

>100_bases
AGGCCGCGTACGACGAACCACCGGCGGGCGCCCCGGAGAACCGACCCATCCATTCGGGCGGGCTGTGTCAGCCCGCCCAC
CGTCGATGAGGATGATCATC

Downstream 100 bases:

>100_bases
CCCGGTGAGAATCGTGATGTCGTGGCTGCGCGAGCAGGTCGGCGGCCTGCCGCCGGCGAAGGCCGTGGCCGACGCGCTGA
TCCGCGCCGGTTTCGAGGTC

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MPAPNETADPVDLGALDPGRLDGAAAAALAAIAGADDLAALSAVRTAHVDGQQAPLMLARRELGALPREHRAEAGRAHNA
ATAKVRAAYEARLVELTARRDAEILVAERVDVTLPVDRRRRGARHPLSLLSDRLTDVFVAMGYEVAEGPEVEHDWFNFEA
LNMAPDHPARSEHDTLYVEPAASGRLLRTHTSPVQIRSLLSRPLPVYVVCPGRTYRNDTIDATHSPVFGQLECLAVDEGI
TMADLRGTLEVFAQALFGSGLSTRLRPSFFPFTEPSAELDVQCFACRGDAARQPCRVCSDEGWIEAGGCGMVDPNVLRAC
GVDPARYSGFAFGMGLERAAMTRHDVREIRDFVDGDVRFGLPFGSEG

Sequences:

>Translated_367_residues
MPAPNETADPVDLGALDPGRLDGAAAAALAAIAGADDLAALSAVRTAHVDGQQAPLMLARRELGALPREHRAEAGRAHNA
ATAKVRAAYEARLVELTARRDAEILVAERVDVTLPVDRRRRGARHPLSLLSDRLTDVFVAMGYEVAEGPEVEHDWFNFEA
LNMAPDHPARSEHDTLYVEPAASGRLLRTHTSPVQIRSLLSRPLPVYVVCPGRTYRNDTIDATHSPVFGQLECLAVDEGI
TMADLRGTLEVFAQALFGSGLSTRLRPSFFPFTEPSAELDVQCFACRGDAARQPCRVCSDEGWIEAGGCGMVDPNVLRAC
GVDPARYSGFAFGMGLERAAMTRHDVREIRDFVDGDVRFGLPFGSEG
>Mature_366_residues
PAPNETADPVDLGALDPGRLDGAAAAALAAIAGADDLAALSAVRTAHVDGQQAPLMLARRELGALPREHRAEAGRAHNAA
TAKVRAAYEARLVELTARRDAEILVAERVDVTLPVDRRRRGARHPLSLLSDRLTDVFVAMGYEVAEGPEVEHDWFNFEAL
NMAPDHPARSEHDTLYVEPAASGRLLRTHTSPVQIRSLLSRPLPVYVVCPGRTYRNDTIDATHSPVFGQLECLAVDEGIT
MADLRGTLEVFAQALFGSGLSTRLRPSFFPFTEPSAELDVQCFACRGDAARQPCRVCSDEGWIEAGGCGMVDPNVLRACG
VDPARYSGFAFGMGLERAAMTRHDVREIRDFVDGDVRFGLPFGSEG

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=286, Percent_Identity=29.020979020979, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1788007, Length=335, Percent_Identity=44.7761194029851, Blast_Score=278, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17508957, Length=287, Percent_Identity=28.2229965156794, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32563657, Length=287, Percent_Identity=28.2229965156794, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321087, Length=400, Percent_Identity=24.75, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI18858079, Length=278, Percent_Identity=30.2158273381295, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 39652; Mature: 39521

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPNETADPVDLGALDPGRLDGAAAAALAAIAGADDLAALSAVRTAHVDGQQAPLMLAR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHH
RELGALPREHRAEAGRAHNAATAKVRAAYEARLVELTARRDAEILVAERVDVTLPVDRRR
HHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEECCHHHHH
RGARHPLSLLSDRLTDVFVAMGYEVAEGPEVEHDWFNFEALNMAPDHPARSEHDTLYVEP
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEC
AASGRLLRTHTSPVQIRSLLSRPLPVYVVCPGRTYRNDTIDATHSPVFGQLECLAVDEGI
CCCCCEEEECCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
TMADLRGTLEVFAQALFGSGLSTRLRPSFFPFTEPSAELDVQCFACRGDAARQPCRVCSD
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHCCC
EGWIEAGGCGMVDPNVLRACGVDPARYSGFAFGMGLERAAMTRHDVREIRDFVDGDVRFG
CCCEEECCCCCCCHHHHHHHCCCHHHHCCEEECCCHHHHHHHHHHHHHHHHHHCCCEEEE
LPFGSEG
CCCCCCC
>Mature Secondary Structure 
PAPNETADPVDLGALDPGRLDGAAAAALAAIAGADDLAALSAVRTAHVDGQQAPLMLAR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHH
RELGALPREHRAEAGRAHNAATAKVRAAYEARLVELTARRDAEILVAERVDVTLPVDRRR
HHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEECCHHHHH
RGARHPLSLLSDRLTDVFVAMGYEVAEGPEVEHDWFNFEALNMAPDHPARSEHDTLYVEP
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEC
AASGRLLRTHTSPVQIRSLLSRPLPVYVVCPGRTYRNDTIDATHSPVFGQLECLAVDEGI
CCCCCEEEECCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
TMADLRGTLEVFAQALFGSGLSTRLRPSFFPFTEPSAELDVQCFACRGDAARQPCRVCSD
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHCCC
EGWIEAGGCGMVDPNVLRACGVDPARYSGFAFGMGLERAAMTRHDVREIRDFVDGDVRFG
CCCEEECCCCCCCHHHHHHHCCCHHHHCCEEECCCHHHHHHHHHHHHHHHHHHCCCEEEE
LPFGSEG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]