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The map label for this gene is infC [H]

Identifier: 158313564

GI number: 158313564

Start: 2066263

End: 2066712

Strand: Direct

Name: infC [H]

Synonym: Franean1_1728

Alternate gene names: 158313564

Gene position: 2066263-2066712 (Clockwise)

Preceding gene: 158313563

Following gene: 158313565

Centisome position: 23.0

GC content: 63.78

Gene sequence:

>450_bases
ATGCGCCTGGCGCAGGAGTCCGACCTCGACCTCGTCGAGGTGGCACCCACTGCCCGTCCGCCGGTCTGCAAGCTGATGGA
CTATGGAAAGTTCAAGTACGAGTCCGACCAGAAGCGTCGCGAGGCTCGTAAGAACCAGGTCCAGACGGTTATCAAGGAGA
TGAAGCTCCGACCGAAGATCGATCCGCACGACTACGAGACCAAGAAGGGTCACGTAGTGCGGTTCCTCAAGGCCGGCGAC
AAGGTCAAGATCACCATCATGTTCCGAGGTCGGGAGCAGTCCCGTCCCGAGCTCGGCATCCGGCTGCTGCAGCGGCTGTC
GACCGACGTGGCCGACCTTGGCTACGTCGAGGCCCAGCCCAAGCAGGACGGCCGGAACATGACGATGGTCATGGCCCCGC
ACAAGGGCGCCAAGCCCCAGCGGACCCCGGAGTCCGCCAGCCAGGTGTAG

Upstream 100 bases:

>100_bases
CAGCACAGAGTCACGTATCAATGACCGGATCCGCGTTCCGGAGGTTCGCCTCGTAGGTGCGGAGGGCGAGCAGATCGGCA
TCGTCTCCATCGGGGAAGCC

Downstream 100 bases:

>100_bases
GTCACGACCGGGCGAAGTCGCAACGACGTGCACACAGCACGGGTACTCCGAACAGGCGCGCCAGCGGCGCGTGCCCGCAA
CCCACCCACAGGGACCGATC

Product: initiation factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRLAQESDLDLVEVAPTARPPVCKLMDYGKFKYESDQKRREARKNQVQTVIKEMKLRPKIDPHDYETKKGHVVRFLKAGD
KVKITIMFRGREQSRPELGIRLLQRLSTDVADLGYVEAQPKQDGRNMTMVMAPHKGAKPQRTPESASQV

Sequences:

>Translated_149_residues
MRLAQESDLDLVEVAPTARPPVCKLMDYGKFKYESDQKRREARKNQVQTVIKEMKLRPKIDPHDYETKKGHVVRFLKAGD
KVKITIMFRGREQSRPELGIRLLQRLSTDVADLGYVEAQPKQDGRNMTMVMAPHKGAKPQRTPESASQV
>Mature_149_residues
MRLAQESDLDLVEVAPTARPPVCKLMDYGKFKYESDQKRREARKNQVQTVIKEMKLRPKIDPHDYETKKGHVVRFLKAGD
KVKITIMFRGREQSRPELGIRLLQRLSTDVADLGYVEAQPKQDGRNMTMVMAPHKGAKPQRTPESASQV

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=133, Percent_Identity=47.3684210526316, Blast_Score=123, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17103; Mature: 17103

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAQESDLDLVEVAPTARPPVCKLMDYGKFKYESDQKRREARKNQVQTVIKEMKLRPKI
CCCCCCCCCCEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DPHDYETKKGHVVRFLKAGDKVKITIMFRGREQSRPELGIRLLQRLSTDVADLGYVEAQP
CCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCC
KQDGRNMTMVMAPHKGAKPQRTPESASQV
CCCCCCEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLAQESDLDLVEVAPTARPPVCKLMDYGKFKYESDQKRREARKNQVQTVIKEMKLRPKI
CCCCCCCCCCEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DPHDYETKKGHVVRFLKAGDKVKITIMFRGREQSRPELGIRLLQRLSTDVADLGYVEAQP
CCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCC
KQDGRNMTMVMAPHKGAKPQRTPESASQV
CCCCCCEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]