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The map label for this gene is ribH [H]

Identifier: 158313561

GI number: 158313561

Start: 2061742

End: 2062224

Strand: Direct

Name: ribH [H]

Synonym: Franean1_1725

Alternate gene names: 158313561

Gene position: 2061742-2062224 (Clockwise)

Preceding gene: 158313560

Following gene: 158313562

Centisome position: 22.95

GC content: 75.36

Gene sequence:

>483_bases
ATGAGCGGCGCCGGAGCACCCGCCGAGGAGCTGCCCGACGCCAGCGGGGTGCGCCTGGCGATCGTGGCCACCCGGTGGCA
TGTGGAGATCACCGACGCGCTGCTCGCCGGCGCGCTGCGCGCGGCGAAGGACTCGGGCGTCACGGCCACGCCAACCGTCG
TGCGGGTCTCCGGGGCCGTCGAGCTGCCCGTGGTCGTCGCCGCTCTGGCGGCGCGCCATGACGCGGTGGTGGCGCTGGGG
GCGGTGATCCGCGGCGGCACCCCGCACTTCGAGTACGTCTGCCGCTTCGTGACGGACGGCCTGGTGCGGATCACCCTCGA
CGCCGGGGTGCCGGTCGGCTTCGGCCTGCTGACCTGCGACACCGTCGAGCAGGCCAGGGACCGTGCCGGCCTGCCGGGCT
CGACGGAGGACAAGGGCCGCGAGGCCACCCTCGCCGCGCTCGACACCGCCGTCATCCTGCGCGGCATCGGTGCCCTCACC
TGA

Upstream 100 bases:

>100_bases
TCGGCGGGGACGAGACCGCCGGCGCGCACGAGGCCCACCGCTGGCCGGTGACGGCGGCCCCGGTCGCCGACCGCGCGGAC
CGGGCCTGCGAGGAGGCCCG

Downstream 100 bases:

>100_bases
CGGGCCGCCGCGGCGCGGCCGGCCGCGGGTAGCCGCCGGCCGTGCTCTCGCCGGGGCCCGGCCACCAGTGTGGGCCCCCG
GTGGGCCGTCGGTCGCCGGG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSGAGAPAEELPDASGVRLAIVATRWHVEITDALLAGALRAAKDSGVTATPTVVRVSGAVELPVVVAALAARHDAVVALG
AVIRGGTPHFEYVCRFVTDGLVRITLDAGVPVGFGLLTCDTVEQARDRAGLPGSTEDKGREATLAALDTAVILRGIGALT

Sequences:

>Translated_160_residues
MSGAGAPAEELPDASGVRLAIVATRWHVEITDALLAGALRAAKDSGVTATPTVVRVSGAVELPVVVAALAARHDAVVALG
AVIRGGTPHFEYVCRFVTDGLVRITLDAGVPVGFGLLTCDTVEQARDRAGLPGSTEDKGREATLAALDTAVILRGIGALT
>Mature_159_residues
SGAGAPAEELPDASGVRLAIVATRWHVEITDALLAGALRAAKDSGVTATPTVVRVSGAVELPVVVAALAARHDAVVALGA
VIRGGTPHFEYVCRFVTDGLVRITLDAGVPVGFGLLTCDTVEQARDRAGLPGSTEDKGREATLAALDTAVILRGIGALT

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=151, Percent_Identity=46.3576158940397, Blast_Score=112, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324429, Length=160, Percent_Identity=35, Blast_Score=87, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16233; Mature: 16102

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAGAPAEELPDASGVRLAIVATRWHVEITDALLAGALRAAKDSGVTATPTVVRVSGAV
CCCCCCCHHHCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
ELPVVVAALAARHDAVVALGAVIRGGTPHFEYVCRFVTDGLVRITLDAGVPVGFGLLTCD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCEEEHH
TVEQARDRAGLPGSTEDKGREATLAALDTAVILRGIGALT
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGAGAPAEELPDASGVRLAIVATRWHVEITDALLAGALRAAKDSGVTATPTVVRVSGAV
CCCCCCHHHCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
ELPVVVAALAARHDAVVALGAVIRGGTPHFEYVCRFVTDGLVRITLDAGVPVGFGLLTCD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCEEEHH
TVEQARDRAGLPGSTEDKGREATLAALDTAVILRGIGALT
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA