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The map label for this gene is ribD [H]

Identifier: 158313558

GI number: 158313558

Start: 2058770

End: 2059258

Strand: Direct

Name: ribD [H]

Synonym: Franean1_1722

Alternate gene names: 158313558

Gene position: 2058770-2059258 (Clockwise)

Preceding gene: 158313557

Following gene: 158313559

Centisome position: 22.92

GC content: 78.73

Gene sequence:

>489_bases
GTGAGCGAGGCACGCGCCGCGGCCGGCGGGCCGCCACTGCCCGGTACCCCGGAAGGCGACCGGCACTGGCTGGGCCGGGC
CGTCGAGCTGGGCCGGCGCTGCCCGCCGTCGGTCACCGCGTTCGCCGTCGGCGCGCTCGTCGTCGCCGCGGACGGGACGC
CGGTCGCCGAGGGCTACTCTCGGGCCGAGGAGCCGGCCGACCATGCCGAGGAGGTGGCGCTGCGCCGGCTGCCGCCGGGC
GGCCTGCCCGCGGGCGCGACCGTGTACAGCTCGCTGGAGCCGTGCAGCGCCCGCGCGTCCCGGCCGCGTACCTGCACCGA
GCTGCTGCTCGCCGCCGGGGTCCGCCGGGTCGTCTTCGCCTGGCGGGAGCCGGCCCTGTTCGTCGACTGCGACGGTGCCG
AGCGGCTGGCCGCCGCCGGTGTCGAGGTGCTCGAGCTCGCCGAGCTCGCTGACGGTGTGCGGGCGGTGAACGACCACCTG
CTGCGGTGA

Upstream 100 bases:

>100_bases
CTTTTGTCTCGCCCCCTGCCCCGGCCCCCGCTCCGGCCCCGGCTCCCGTCGCTGATCGTGAGGCGGGTGGCGGGGCGGCC
GCCGTCGGCGGGGTGCCGGC

Downstream 100 bases:

>100_bases
CCGCCGGGGGCGTCCCGCGCGGTTTCCCGGTGGGGATGACGTGGATTACTGTCCGCGCCCCGAGCGTTCGCGGCGCCTGT
ATGTCAGACTTAACCGTGTA

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSEARAAAGGPPLPGTPEGDRHWLGRAVELGRRCPPSVTAFAVGALVVAADGTPVAEGYSRAEEPADHAEEVALRRLPPG
GLPAGATVYSSLEPCSARASRPRTCTELLLAAGVRRVVFAWREPALFVDCDGAERLAAAGVEVLELAELADGVRAVNDHL
LR

Sequences:

>Translated_162_residues
MSEARAAAGGPPLPGTPEGDRHWLGRAVELGRRCPPSVTAFAVGALVVAADGTPVAEGYSRAEEPADHAEEVALRRLPPG
GLPAGATVYSSLEPCSARASRPRTCTELLLAAGVRRVVFAWREPALFVDCDGAERLAAAGVEVLELAELADGVRAVNDHL
LR
>Mature_161_residues
SEARAAAGGPPLPGTPEGDRHWLGRAVELGRRCPPSVTAFAVGALVVAADGTPVAEGYSRAEEPADHAEEVALRRLPPGG
LPAGATVYSSLEPCSARASRPRTCTELLLAAGVRRVVFAWREPALFVDCDGAERLAAAGVEVLELAELADGVRAVNDHLL
R

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=125, Percent_Identity=40, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324506, Length=139, Percent_Identity=33.8129496402878, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 16869; Mature: 16738

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEARAAAGGPPLPGTPEGDRHWLGRAVELGRRCPPSVTAFAVGALVVAADGTPVAEGYS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCCHHHHHH
RAEEPADHAEEVALRRLPPGGLPAGATVYSSLEPCSARASRPRTCTELLLAAGVRRVVFA
HHCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
WREPALFVDCDGAERLAAAGVEVLELAELADGVRAVNDHLLR
HCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEARAAAGGPPLPGTPEGDRHWLGRAVELGRRCPPSVTAFAVGALVVAADGTPVAEGYS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCCHHHHHH
RAEEPADHAEEVALRRLPPGGLPAGATVYSSLEPCSARASRPRTCTELLLAAGVRRVVFA
HHCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
WREPALFVDCDGAERLAAAGVEVLELAELADGVRAVNDHLLR
HCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]