Click here to switch to the map view.

The map label for this gene is pyrR [H]

Identifier: 158313541

GI number: 158313541

Start: 2036972

End: 2037565

Strand: Direct

Name: pyrR [H]

Synonym: Franean1_1705

Alternate gene names: 158313541

Gene position: 2036972-2037565 (Clockwise)

Preceding gene: 158313539

Following gene: 158313542

Centisome position: 22.68

GC content: 74.75

Gene sequence:

>594_bases
GTGAGCAGCACCCCCACCGGATCCGAGGGGCTCACCGGGTCCGAGGGGCTCGGCATCACCCGCACCGTGCTCTCCGCCGC
CGACATGAACCGGGTTGTGAGCCGGATGGCGCACCAGGTGCTGGAGAAGACCTCCGGCGGCGACGGCGTGGTCCTGCTCG
GCATCCCGACCCGCGGCGTGCCGCTCGCGGAGCGGCTGGCGCGCCGGGTGGCCGCGGTCGAGGGCGTGACCCTTCCCGTG
GGCTCCCTGGACCCGACGATGTACCGGGACGACCTGCGGCTGCGCGGCGTGCGCCCGCTCGAGGTGACCGAGATCCCCGA
CTGCGGGGTCGACGGGATGGTCGTCGTCCTGGTCGACGACGTCCTCTACTCCGGGCGCACCGCCCGGGCCGCGCTCGACG
CGCTGTCCGCCTATGGCCGCCCCCGCGCTGTGCAGCTCGCCGTCCTGGTCGACCGGGGCCACCGCGAGCTGCCCATCCGC
GCCGACTACGTGGGGAAGAACATGCCCACCTCGCGCCGCGAGTCGGTCGCCGTCCGGCTCCGGGAGGTCGACGGCGCCGA
CGCCGTCCTCATCGTCTCGTCGGACGCGCCGTGA

Upstream 100 bases:

>100_bases
CGTGGCCTCGGCCGCACAAGGCGACCCTGCCCGGAACACGACCGGGCGTACCGGGCGTACCGCCCGTCCACGGGACGAGC
TCCGTGCCGGGACGGCCGAT

Downstream 100 bases:

>100_bases
CCGCGCACGCGACCCCGCGCCGCCGTCCGAGGTGGTGGGTGTGATGAACCATCTGCTTTCCACCGCGGATCTCAAGCTCG
ACGACGCGCTGCTGGTGCTC

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSSTPTGSEGLTGSEGLGITRTVLSAADMNRVVSRMAHQVLEKTSGGDGVVLLGIPTRGVPLAERLARRVAAVEGVTLPV
GSLDPTMYRDDLRLRGVRPLEVTEIPDCGVDGMVVVLVDDVLYSGRTARAALDALSAYGRPRAVQLAVLVDRGHRELPIR
ADYVGKNMPTSRRESVAVRLREVDGADAVLIVSSDAP

Sequences:

>Translated_197_residues
MSSTPTGSEGLTGSEGLGITRTVLSAADMNRVVSRMAHQVLEKTSGGDGVVLLGIPTRGVPLAERLARRVAAVEGVTLPV
GSLDPTMYRDDLRLRGVRPLEVTEIPDCGVDGMVVVLVDDVLYSGRTARAALDALSAYGRPRAVQLAVLVDRGHRELPIR
ADYVGKNMPTSRRESVAVRLREVDGADAVLIVSSDAP
>Mature_196_residues
SSTPTGSEGLTGSEGLGITRTVLSAADMNRVVSRMAHQVLEKTSGGDGVVLLGIPTRGVPLAERLARRVAAVEGVTLPVG
SLDPTMYRDDLRLRGVRPLEVTEIPDCGVDGMVVVLVDDVLYSGRTARAALDALSAYGRPRAVQLAVLVDRGHRELPIRA
DYVGKNMPTSRRESVAVRLREVDGADAVLIVSSDAP

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20853; Mature: 20722

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTPTGSEGLTGSEGLGITRTVLSAADMNRVVSRMAHQVLEKTSGGDGVVLLGIPTRGV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
PLAERLARRVAAVEGVTLPVGSLDPTMYRDDLRLRGVRPLEVTEIPDCGVDGMVVVLVDD
CHHHHHHHHHHHHCCCEECCCCCCCHHHHCCHHHCCCCCCEECCCCCCCCCCEEEEEEEH
VLYSGRTARAALDALSAYGRPRAVQLAVLVDRGHRELPIRADYVGKNMPTSRRESVAVRL
HHHCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCCCHHHHHEEEE
REVDGADAVLIVSSDAP
EECCCCCEEEEEECCCC
>Mature Secondary Structure 
SSTPTGSEGLTGSEGLGITRTVLSAADMNRVVSRMAHQVLEKTSGGDGVVLLGIPTRGV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
PLAERLARRVAAVEGVTLPVGSLDPTMYRDDLRLRGVRPLEVTEIPDCGVDGMVVVLVDD
CHHHHHHHHHHHHCCCEECCCCCCCHHHHCCHHHCCCCCCEECCCCCCCCCCEEEEEEEH
VLYSGRTARAALDALSAYGRPRAVQLAVLVDRGHRELPIRADYVGKNMPTSRRESVAVRL
HHHCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCCCHHHHHEEEE
REVDGADAVLIVSSDAP
EECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]