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The map label for this gene is insF1 [H]

Identifier: 158313229

GI number: 158313229

Start: 1676778

End: 1677692

Strand: Direct

Name: insF1 [H]

Synonym: Franean1_1384

Alternate gene names: 158313229

Gene position: 1676778-1677692 (Clockwise)

Preceding gene: 158313228

Following gene: 158313231

Centisome position: 18.67

GC content: 64.81

Gene sequence:

>915_bases
GTGAGCGACACGTTCGAGTTCATCGATGCGGAGTACGCCGCCCGCACCACCACGAACACCAGTGCACCAGCGCCGTCGGT
CATCCAGATGTGCGCCTGGCTTAGTGTCTCCCGTTCGGGTTTCTACGAGTGGCGTGACCGCCCCGCCTCCGCGACCGCGA
CCCGCCGCGGCGCACTCGCCACACTCGTCGTTCGGTCGTTCACCGCCTCCGACGGCACCTACGGCTACCGCCGTGTGCAC
TCTGACCTGCTCGCCTGGGGCCGCCCCTGCAGCCCCGAGCTCGTCCGCGCCCTCATGCGCGAGCAGGGCCTGGTGCCCTG
CCAGCCCCGCCCCTGGCGACACACCCTGACCGAGCCCGGCCAGACCCCGGCCGCGATCCCCGACCTGCTGCAGCGCGACT
TCACCGCCGACACTCCCGGAACCAAAATGGTCGGCGACATCACCTACATTCCCACCTGGGAAGGCTGGCTGTATCTCGCG
ACCGTCATCGACTGCCACACGAAAGCCGTCATCGGCTGGGCAATGGACGACAACTACAAGACCGGGCTCATCGAAACAGC
CATCACCATGGCCGCCCGTAACCACCAGCTCACCGACGGGGCGATTTTTCATTCGGACCGCGGAAGCAACTATACGTCTA
CCCAGTTCGCTGCTACGTTGAAGAACCTCGGGATCCGCCAGTCCGTCGGCCGGACCGGAATTTGCTATGACAATGCGATG
GCCGAGTCCTTCTTCGCAGCTCTCAAGAACGAACGCGTCCACCGCACCGCCTATCCCACCCGAGAACACGCCCGACGCGA
CATTGCCCGATACATCGAACTTCGCTACAATACGACACGCCGCCACTCGGGACTCGACTACCGAACCCCGCAGCAGGTCC
ACGACGAGTACCTGAAAAGGCAGACCGCCGCATAG

Upstream 100 bases:

>100_bases
AACGCGCCCGGCTACGTGAACTCGAGCGGCAGAACCGCGAGCTGCGCATGGAAAACGAGTTCCTGAAAAAAGCCGCAGCG
TACTTCGCCAAGGATCATCG

Downstream 100 bases:

>100_bases
CCCAGACCTATAACGACTGTCCGGAATTAACGGGGCACATCACAGGCCGAGGGGACGCGTCCGAGGCCGAGTGGTAGAGG
TTGCCTTCGCACTCAAGCGC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSDTFEFIDAEYAARTTTNTSAPAPSVIQMCAWLSVSRSGFYEWRDRPASATATRRGALATLVVRSFTASDGTYGYRRVH
SDLLAWGRPCSPELVRALMREQGLVPCQPRPWRHTLTEPGQTPAAIPDLLQRDFTADTPGTKMVGDITYIPTWEGWLYLA
TVIDCHTKAVIGWAMDDNYKTGLIETAITMAARNHQLTDGAIFHSDRGSNYTSTQFAATLKNLGIRQSVGRTGICYDNAM
AESFFAALKNERVHRTAYPTREHARRDIARYIELRYNTTRRHSGLDYRTPQQVHDEYLKRQTAA

Sequences:

>Translated_304_residues
MSDTFEFIDAEYAARTTTNTSAPAPSVIQMCAWLSVSRSGFYEWRDRPASATATRRGALATLVVRSFTASDGTYGYRRVH
SDLLAWGRPCSPELVRALMREQGLVPCQPRPWRHTLTEPGQTPAAIPDLLQRDFTADTPGTKMVGDITYIPTWEGWLYLA
TVIDCHTKAVIGWAMDDNYKTGLIETAITMAARNHQLTDGAIFHSDRGSNYTSTQFAATLKNLGIRQSVGRTGICYDNAM
AESFFAALKNERVHRTAYPTREHARRDIARYIELRYNTTRRHSGLDYRTPQQVHDEYLKRQTAA
>Mature_303_residues
SDTFEFIDAEYAARTTTNTSAPAPSVIQMCAWLSVSRSGFYEWRDRPASATATRRGALATLVVRSFTASDGTYGYRRVHS
DLLAWGRPCSPELVRALMREQGLVPCQPRPWRHTLTEPGQTPAAIPDLLQRDFTADTPGTKMVGDITYIPTWEGWLYLAT
VIDCHTKAVIGWAMDDNYKTGLIETAITMAARNHQLTDGAIFHSDRGSNYTSTQFAATLKNLGIRQSVGRTGICYDNAMA
ESFFAALKNERVHRTAYPTREHARRDIARYIELRYNTTRRHSGLDYRTPQQVHDEYLKRQTAA

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=198, Percent_Identity=33.8383838383838, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI1788405, Length=275, Percent_Identity=38.1818181818182, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1787263, Length=275, Percent_Identity=38.1818181818182, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1786753, Length=275, Percent_Identity=38.1818181818182, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1786570, Length=275, Percent_Identity=38.1818181818182, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1786490, Length=275, Percent_Identity=38.1818181818182, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1789981, Length=231, Percent_Identity=31.1688311688312, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 34265; Mature: 34134

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTFEFIDAEYAARTTTNTSAPAPSVIQMCAWLSVSRSGFYEWRDRPASATATRRGALA
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHH
TLVVRSFTASDGTYGYRRVHSDLLAWGRPCSPELVRALMREQGLVPCQPRPWRHTLTEPG
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QTPAAIPDLLQRDFTADTPGTKMVGDITYIPTWEGWLYLATVIDCHTKAVIGWAMDDNYK
CCCHHHHHHHHHCCCCCCCCCCEEECEEEECCCCCHHHHHHHHHHHHHEEEEEEECCCCC
TGLIETAITMAARNHQLTDGAIFHSDRGSNYTSTQFAATLKNLGIRQSVGRTGICYDNAM
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHHCCCCCCEEHHHH
AESFFAALKNERVHRTAYPTREHARRDIARYIELRYNTTRRHSGLDYRTPQQVHDEYLKR
HHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHH
QTAA
HCCC
>Mature Secondary Structure 
SDTFEFIDAEYAARTTTNTSAPAPSVIQMCAWLSVSRSGFYEWRDRPASATATRRGALA
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHH
TLVVRSFTASDGTYGYRRVHSDLLAWGRPCSPELVRALMREQGLVPCQPRPWRHTLTEPG
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QTPAAIPDLLQRDFTADTPGTKMVGDITYIPTWEGWLYLATVIDCHTKAVIGWAMDDNYK
CCCHHHHHHHHHCCCCCCCCCCEEECEEEECCCCCHHHHHHHHHHHHHEEEEEEECCCCC
TGLIETAITMAARNHQLTDGAIFHSDRGSNYTSTQFAATLKNLGIRQSVGRTGICYDNAM
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHHCCCCCCEEHHHH
AESFFAALKNERVHRTAYPTREHARRDIARYIELRYNTTRRHSGLDYRTPQQVHDEYLKR
HHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHH
QTAA
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]