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The map label for this gene is acuC [H]

Identifier: 158313091

GI number: 158313091

Start: 1487359

End: 1488666

Strand: Direct

Name: acuC [H]

Synonym: Franean1_1239

Alternate gene names: 158313091

Gene position: 1487359-1488666 (Clockwise)

Preceding gene: 158313089

Following gene: 158313092

Centisome position: 16.56

GC content: 76.45

Gene sequence:

>1308_bases
GTGCGGGACGTCGCGCGGAGCTACCGTCGTCGTGTGAGCACGTCCGCGAACACCGAGCCCTCGCCGGCCGCGCCCGGAGC
GGGTGCGCAGGCCCTCCTCATCTGGGACAGGGCGATGCTCGACTACGACTTCGGCCCGACCCATCCGCTGCACCCGGTGC
GGCTCGCGCTGACGATGGATCTCGCCGGCGCCGTCGGCCTGCTCGACGCCCCGGGGATCACCGTCGCCTCTGCGGGGATG
GCCGGCGACGACCTGATCGAGCTCGTCCACGACCCCGCCTACCTCAGTGCGGTGCGCGCGGCGTCGCCGGGGTCGCGGGC
CGGGTCGCTGCTGGCGGGCCGCTTCGGGCTGGGCACCGCCGACAACCCGGTCTTCGACCGGATGCACGCCGCCGCCGCGC
TGGTGACCGGCGGGACGCTCGCCGCCGCCGAGGCGGTGTGGAAGGGCACCCACCAGCACGCGGTGTCGCTGGCCGGGGGC
CTGCACCACGCGATGCGCGGTTCGGCCAGCGGGTTCTGCGTCTACAACGATCCGGCCGTCGCGATCGCCTGGCTGCTGTC
CGCCGGCGCGAGCCGGGTCGCCTACGTCGACATCGACGTGCACCACGGCGACGGCGTCCAGGCGGCCTTCTACGACGATC
CGCGGGTGCTCACGATCTCGCTGCACCAGAGCGGGCGGTCGCTGTTCCCCGGCACCGGTTTCGCCCGGGAGGTCGGCACG
GGTGACGCCGAGGGCACGGCGGTGAACGTTGCGCTGCCGCCCGGGACGGGCGACGCCGGTTGGCTGCGCGCGTTCTCCGG
GGTGGTCCCGGTGATGCTGCGCGCGTTCCGCCCGCAGGTCCTGGTCACCCAGCACGGGTGCGACACGCACGCGCTCGACC
CGCTGGCCGACCTGCGGCTCTCCCTCGACGGCCAGCGCGCCTCCTACGAGGCGCTGCACCAGCTGGCCCACGAGGTGTGC
GGCGGGCGCTGGCTCGCCTGCGGGGGCGGTGGCTACGCCCTGGACGCCGTCGTGCCGCGGGCCTGGACGCAGCTCGTCGC
GATCGCCGCCCACACCCCGCTGGACGCGGCCCGGGCGCTGCCCGAGGAGTGGGCCGCCGCGGCCCCGGCCCGGGTCCGCG
CGGCGACGGGCCACGACTCGGTCGGCGCCGCCGGGATGCCGTCGACCTTCGGCGACGGCGCCCCGGCCGCCTACCACCCG
TGGGACGCCGGCGAGGGCGACCCCGACGACCCGCTGGACCGCTCGGTCGCGCAGACCCGCAGCGCGGTGCTCCCGCTGCA
CGGGCTCGACCCGCTAGTGGACCGGTGA

Upstream 100 bases:

>100_bases
GTCCGTCCACAGTGTCGCCGGTGCGCCGGGCCGGCGCCGGCCCCCGCTCACGCGGCCGGGGACGGCTGTTCCGGCCACGG
CGGGTGTCGTCAGGACAGTC

Downstream 100 bases:

>100_bases
ACGCCGGCCCCGATCCTGGCCTGCCGCGCGACTACCCCGCCCACTGGGAGGCCGACGTCATCCTGTCGGACGGCGGGACG
GCGCATATCCGTCCGATCCG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MRDVARSYRRRVSTSANTEPSPAAPGAGAQALLIWDRAMLDYDFGPTHPLHPVRLALTMDLAGAVGLLDAPGITVASAGM
AGDDLIELVHDPAYLSAVRAASPGSRAGSLLAGRFGLGTADNPVFDRMHAAAALVTGGTLAAAEAVWKGTHQHAVSLAGG
LHHAMRGSASGFCVYNDPAVAIAWLLSAGASRVAYVDIDVHHGDGVQAAFYDDPRVLTISLHQSGRSLFPGTGFAREVGT
GDAEGTAVNVALPPGTGDAGWLRAFSGVVPVMLRAFRPQVLVTQHGCDTHALDPLADLRLSLDGQRASYEALHQLAHEVC
GGRWLACGGGGYALDAVVPRAWTQLVAIAAHTPLDAARALPEEWAAAAPARVRAATGHDSVGAAGMPSTFGDGAPAAYHP
WDAGEGDPDDPLDRSVAQTRSAVLPLHGLDPLVDR

Sequences:

>Translated_435_residues
MRDVARSYRRRVSTSANTEPSPAAPGAGAQALLIWDRAMLDYDFGPTHPLHPVRLALTMDLAGAVGLLDAPGITVASAGM
AGDDLIELVHDPAYLSAVRAASPGSRAGSLLAGRFGLGTADNPVFDRMHAAAALVTGGTLAAAEAVWKGTHQHAVSLAGG
LHHAMRGSASGFCVYNDPAVAIAWLLSAGASRVAYVDIDVHHGDGVQAAFYDDPRVLTISLHQSGRSLFPGTGFAREVGT
GDAEGTAVNVALPPGTGDAGWLRAFSGVVPVMLRAFRPQVLVTQHGCDTHALDPLADLRLSLDGQRASYEALHQLAHEVC
GGRWLACGGGGYALDAVVPRAWTQLVAIAAHTPLDAARALPEEWAAAAPARVRAATGHDSVGAAGMPSTFGDGAPAAYHP
WDAGEGDPDDPLDRSVAQTRSAVLPLHGLDPLVDR
>Mature_435_residues
MRDVARSYRRRVSTSANTEPSPAAPGAGAQALLIWDRAMLDYDFGPTHPLHPVRLALTMDLAGAVGLLDAPGITVASAGM
AGDDLIELVHDPAYLSAVRAASPGSRAGSLLAGRFGLGTADNPVFDRMHAAAALVTGGTLAAAEAVWKGTHQHAVSLAGG
LHHAMRGSASGFCVYNDPAVAIAWLLSAGASRVAYVDIDVHHGDGVQAAFYDDPRVLTISLHQSGRSLFPGTGFAREVGT
GDAEGTAVNVALPPGTGDAGWLRAFSGVVPVMLRAFRPQVLVTQHGCDTHALDPLADLRLSLDGQRASYEALHQLAHEVC
GGRWLACGGGGYALDAVVPRAWTQLVAIAAHTPLDAARALPEEWAAAAPARVRAATGHDSVGAAGMPSTFGDGAPAAYHP
WDAGEGDPDDPLDRSVAQTRSAVLPLHGLDPLVDR

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128860, Length=330, Percent_Identity=34.5454545454545, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI293336691, Length=288, Percent_Identity=34.0277777777778, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI13128862, Length=337, Percent_Identity=32.3442136498516, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI8923769, Length=327, Percent_Identity=31.8042813455657, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI262073088, Length=226, Percent_Identity=35.8407079646018, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI30795202, Length=183, Percent_Identity=37.1584699453552, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI17158039, Length=183, Percent_Identity=37.1584699453552, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI30795204, Length=183, Percent_Identity=37.1584699453552, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI262073092, Length=212, Percent_Identity=32.5471698113208, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI20070354, Length=314, Percent_Identity=30.8917197452229, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI169234807, Length=133, Percent_Identity=45.1127819548872, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI148539870, Length=133, Percent_Identity=45.1127819548872, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI153085395, Length=183, Percent_Identity=38.7978142076503, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI13128864, Length=321, Percent_Identity=30.8411214953271, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI62750349, Length=361, Percent_Identity=29.6398891966759, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI62750347, Length=361, Percent_Identity=29.6398891966759, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI226529806, Length=314, Percent_Identity=30.5732484076433, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI209862883, Length=169, Percent_Identity=32.5443786982249, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI217272877, Length=202, Percent_Identity=31.6831683168317, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508561, Length=315, Percent_Identity=35.5555555555556, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17561978, Length=324, Percent_Identity=33.0246913580247, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17534739, Length=303, Percent_Identity=31.6831683168317, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI193209491, Length=239, Percent_Identity=33.0543933054393, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540334, Length=369, Percent_Identity=25.2032520325203, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17540332, Length=369, Percent_Identity=25.2032520325203, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193206283, Length=369, Percent_Identity=25.2032520325203, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25154022, Length=317, Percent_Identity=23.9747634069401, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25154020, Length=304, Percent_Identity=23.0263157894737, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321244, Length=333, Percent_Identity=32.7327327327327, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6323999, Length=352, Percent_Identity=31.25, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6324307, Length=317, Percent_Identity=27.7602523659306, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6325325, Length=225, Percent_Identity=29.3333333333333, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24657891, Length=336, Percent_Identity=33.0357142857143, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24644244, Length=337, Percent_Identity=34.1246290801187, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24642144, Length=303, Percent_Identity=29.7029702970297, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24642142, Length=303, Percent_Identity=29.7029702970297, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24642146, Length=303, Percent_Identity=29.7029702970297, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI281360899, Length=303, Percent_Identity=29.7029702970297, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI281360801, Length=134, Percent_Identity=40.2985074626866, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360799, Length=134, Percent_Identity=40.2985074626866, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641720, Length=134, Percent_Identity=40.2985074626866, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 44910; Mature: 44910

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDVARSYRRRVSTSANTEPSPAAPGAGAQALLIWDRAMLDYDFGPTHPLHPVRLALTMD
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCCCCCCCCEEEEEEEH
LAGAVGLLDAPGITVASAGMAGDDLIELVHDPAYLSAVRAASPGSRAGSLLAGRFGLGTA
HHCCCCCCCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEECCCCCCCC
DNPVFDRMHAAAALVTGGTLAAAEAVWKGTHQHAVSLAGGLHHAMRGSASGFCVYNDPAV
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
AIAWLLSAGASRVAYVDIDVHHGDGVQAAFYDDPRVLTISLHQSGRSLFPGTGFAREVGT
HHHHHHHCCCCEEEEEEEEEECCCCCEEEEECCCEEEEEEEECCCCCCCCCCCCHHHCCC
GDAEGTAVNVALPPGTGDAGWLRAFSGVVPVMLRAFRPQVLVTQHGCDTHALDPLADLRL
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHE
SLDGQRASYEALHQLAHEVCGGRWLACGGGGYALDAVVPRAWTQLVAIAAHTPLDAARAL
ECCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHCC
PEEWAAAAPARVRAATGHDSVGAAGMPSTFGDGAPAAYHPWDAGEGDPDDPLDRSVAQTR
CHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SAVLPLHGLDPLVDR
HHCCCCCCCCHHHCC
>Mature Secondary Structure
MRDVARSYRRRVSTSANTEPSPAAPGAGAQALLIWDRAMLDYDFGPTHPLHPVRLALTMD
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCCCCCCCCEEEEEEEH
LAGAVGLLDAPGITVASAGMAGDDLIELVHDPAYLSAVRAASPGSRAGSLLAGRFGLGTA
HHCCCCCCCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEECCCCCCCC
DNPVFDRMHAAAALVTGGTLAAAEAVWKGTHQHAVSLAGGLHHAMRGSASGFCVYNDPAV
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
AIAWLLSAGASRVAYVDIDVHHGDGVQAAFYDDPRVLTISLHQSGRSLFPGTGFAREVGT
HHHHHHHCCCCEEEEEEEEEECCCCCEEEEECCCEEEEEEEECCCCCCCCCCCCHHHCCC
GDAEGTAVNVALPPGTGDAGWLRAFSGVVPVMLRAFRPQVLVTQHGCDTHALDPLADLRL
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHE
SLDGQRASYEALHQLAHEVCGGRWLACGGGGYALDAVVPRAWTQLVAIAAHTPLDAARAL
ECCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHCC
PEEWAAAAPARVRAATGHDSVGAAGMPSTFGDGAPAAYHPWDAGEGDPDDPLDRSVAQTR
CHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SAVLPLHGLDPLVDR
HHCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]