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The map label for this gene is nrdR

Identifier: 158313086

GI number: 158313086

Start: 1476776

End: 1477336

Strand: Direct

Name: nrdR

Synonym: Franean1_1234

Alternate gene names: 158313086

Gene position: 1476776-1477336 (Clockwise)

Preceding gene: 158313085

Following gene: 158313087

Centisome position: 16.44

GC content: 74.15

Gene sequence:

>561_bases
ATGCGGTGCCCTTTCTGCCGGCATCCCGACAGCCGTGTCGTCGACAGCAGGGAGGCCGAGGAGGGCGCCGCGATCCGGCG
CCGGCGGTCGTGTCCGGCCTGTGGCCGTCGGTTCACGACCATGGAGGAGGCCTCCTTGCGGGTCCGTAAGCGCAGCGGGG
CCACCGAGCCCTTCAGCCGCGCGAAGGTGATCGTGGGAGTGCGCAAGGCGTGCCAGGGCCGCCCCGTCCGGTCGGACGAT
CTGGCGCTGCTGGCGGAGCGGGTCGAGGAGACGGTGCGCTCCTCGGGCTCCGCGGAGGTGGCCGCCGAGGATGTCGGCCG
AGCGATCCTCGGCCCCCTCCGGGAGTTGGACGAGGTGGCCTACCTCCGCTTCGCCTCCGTCTACCTGGCGTTCGAGTCGC
TCGGCGACTTCGAGGCGGCGATCGCGGCCCTGCGTGCCGAGTCGGCTGGCGGCGGTGAGCCGCCCGTCGCCGGAAAGCCG
ACCACGATGCCGGCGGCCACCGGGGCCTCGGCTGTCATCGTTCCGGTGACCACGGGCCCACGGGCGGCGGCCGGCCCCTG
A

Upstream 100 bases:

>100_bases
ACCGTCTGTCCACAGGGCCGCCGGTCGAGGTGACGGAACCCAGTCGGACGCACCCCGCGGGCGGCAGTGTCAGCCTGCCC
GGGGTGGAGGGGAGCGGACC

Downstream 100 bases:

>100_bases
CGCACCGGCCCGAGGTCCCGGAACCGGGATCCGGGCATCCATGAGTGACCCAGCCTGATCCGCACCGGCCTCACGAACCC
GGGCCGGTGGGCCGCCTGCC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MRCPFCRHPDSRVVDSREAEEGAAIRRRRSCPACGRRFTTMEEASLRVRKRSGATEPFSRAKVIVGVRKACQGRPVRSDD
LALLAERVEETVRSSGSAEVAAEDVGRAILGPLRELDEVAYLRFASVYLAFESLGDFEAAIAALRAESAGGGEPPVAGKP
TTMPAATGASAVIVPVTTGPRAAAGP

Sequences:

>Translated_186_residues
MRCPFCRHPDSRVVDSREAEEGAAIRRRRSCPACGRRFTTMEEASLRVRKRSGATEPFSRAKVIVGVRKACQGRPVRSDD
LALLAERVEETVRSSGSAEVAAEDVGRAILGPLRELDEVAYLRFASVYLAFESLGDFEAAIAALRAESAGGGEPPVAGKP
TTMPAATGASAVIVPVTTGPRAAAGP
>Mature_186_residues
MRCPFCRHPDSRVVDSREAEEGAAIRRRRSCPACGRRFTTMEEASLRVRKRSGATEPFSRAKVIVGVRKACQGRPVRSDD
LALLAERVEETVRSSGSAEVAAEDVGRAILGPLRELDEVAYLRFASVYLAFESLGDFEAAIAALRAESAGGGEPPVAGKP
TTMPAATGASAVIVPVTTGPRAAAGP

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=42.8571428571429, Blast_Score=127, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_FRASN (A8L6K6)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001505594.1
- GeneID:   5669647
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_1234
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   FSP1855:FRANEAN1_1234-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 19668; Mature: 19668

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCRHPDSRVVDSREAEEGAAIRRRRSCPACGRRFTTMEEASLRVRKRSGATEPFSR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHCCCCCCHHH
AKVIVGVRKACQGRPVRSDDLALLAERVEETVRSSGSAEVAAEDVGRAILGPLRELDEVA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
YLRFASVYLAFESLGDFEAAIAALRAESAGGGEPPVAGKPTTMPAATGASAVIVPVTTGP
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
RAAAGP
CCCCCC
>Mature Secondary Structure
MRCPFCRHPDSRVVDSREAEEGAAIRRRRSCPACGRRFTTMEEASLRVRKRSGATEPFSR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHCCCCCCHHH
AKVIVGVRKACQGRPVRSDDLALLAERVEETVRSSGSAEVAAEDVGRAILGPLRELDEVA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
YLRFASVYLAFESLGDFEAAIAALRAESAGGGEPPVAGKPTTMPAATGASAVIVPVTTGP
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
RAAAGP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA