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The map label for this gene is pyrH [H]

Identifier: 158313015

GI number: 158313015

Start: 1385910

End: 1386707

Strand: Direct

Name: pyrH [H]

Synonym: Franean1_1163

Alternate gene names: 158313015

Gene position: 1385910-1386707 (Clockwise)

Preceding gene: 158313014

Following gene: 158313016

Centisome position: 15.43

GC content: 69.92

Gene sequence:

>798_bases
GTGACCGATGACGCCGACAGTGCCGTTGGAGGGGTGGATCCCGCCGCCCGCACCGAGCCCGGGCCGCGGTGGACCCGCCT
CCTGCTGAAACTCTCCGGCGAGGCCTTCGCCGGTGGTGAGCCGCTCGGGATCGACCCGGTGACGCTGGCGACGATCGCGC
GCCAGATCGCCCAGGTGAGCCGCTCGGGCATCGAGGTCGCCATAGTCGTGGGGGCCGGCAACATGTTCCGCGGCCAGGCG
CTCGCCGAGCGGGGCATGGACCGCGCCCGCGCCGACTACATGGGCATGCTGGGCACGGTCATCAACTGCCTGGCCCTGCA
GGACGTCCTGGAGCGCGAGGGGATCGTCACCCGCGTGCAGACGGCGATCGCCATGGGCCAGGTCGCCGAGCCCTACCTCC
CCCTGCGCGCGATCCGGCACCTGGAGAAGGGGCGCGTGGTCATCTTCGGCGCCGGCCTTGGGGCACCGTTCTTCTCGACG
GACACCACCGCCGCCCAGCGGGCACTGGAGATCAAGGCGCAGGCGGTACTCAAGGCGACGAAGGTCGACGGGGTCTACGA
CTCCGATCCGGCGACGAACGCCGGCGCCGTCCGGTTCGACAGCCTCACCTACAGCGAGGTCCTCGCGCGCGGCCTGAAGG
TCATGGACGCGACCGCGATCAGCCTGTGCATGGACAACGACCTGCCCATTGTCGTTTTCGACCTCCTGACCGAGGGGAAC
ATCTCCCGCGCCGTCCGGGGTGAGAAGATCGGCACGCTGGTCGGAGTCGAGACGTACGGAACGGAAGGTACGCGGTGA

Upstream 100 bases:

>100_bases
ACGCGGGGCCACGGGCAGCCGTGCCGGAGTCGTGCGGCAGACTGCTGTCAGCATGAACATCCTTGGCCGCTGATCCCGGC
CGCCGGCGAAGGAGCCGCCC

Downstream 100 bases:

>100_bases
TCGACGACACGCTCCTCGAGGCCGAGGAGAAGATGGACAAGGCCGTCTCGGTCGCCAAGGACGACTTCGCCAACATCCGC
ACGGGGCGGATCACGCCAGC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTDDADSAVGGVDPAARTEPGPRWTRLLLKLSGEAFAGGEPLGIDPVTLATIARQIAQVSRSGIEVAIVVGAGNMFRGQA
LAERGMDRARADYMGMLGTVINCLALQDVLEREGIVTRVQTAIAMGQVAEPYLPLRAIRHLEKGRVVIFGAGLGAPFFST
DTTAAQRALEIKAQAVLKATKVDGVYDSDPATNAGAVRFDSLTYSEVLARGLKVMDATAISLCMDNDLPIVVFDLLTEGN
ISRAVRGEKIGTLVGVETYGTEGTR

Sequences:

>Translated_265_residues
MTDDADSAVGGVDPAARTEPGPRWTRLLLKLSGEAFAGGEPLGIDPVTLATIARQIAQVSRSGIEVAIVVGAGNMFRGQA
LAERGMDRARADYMGMLGTVINCLALQDVLEREGIVTRVQTAIAMGQVAEPYLPLRAIRHLEKGRVVIFGAGLGAPFFST
DTTAAQRALEIKAQAVLKATKVDGVYDSDPATNAGAVRFDSLTYSEVLARGLKVMDATAISLCMDNDLPIVVFDLLTEGN
ISRAVRGEKIGTLVGVETYGTEGTR
>Mature_264_residues
TDDADSAVGGVDPAARTEPGPRWTRLLLKLSGEAFAGGEPLGIDPVTLATIARQIAQVSRSGIEVAIVVGAGNMFRGQAL
AERGMDRARADYMGMLGTVINCLALQDVLEREGIVTRVQTAIAMGQVAEPYLPLRAIRHLEKGRVVIFGAGLGAPFFSTD
TTAAQRALEIKAQAVLKATKVDGVYDSDPATNAGAVRFDSLTYSEVLARGLKVMDATAISLCMDNDLPIVVFDLLTEGNI
SRAVRGEKIGTLVGVETYGTEGTR

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=237, Percent_Identity=48.5232067510549, Blast_Score=219, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 27964; Mature: 27833

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDDADSAVGGVDPAARTEPGPRWTRLLLKLSGEAFAGGEPLGIDPVTLATIARQIAQVS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RSGIEVAIVVGAGNMFRGQALAERGMDRARADYMGMLGTVINCLALQDVLEREGIVTRVQ
HCCCEEEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
TAIAMGQVAEPYLPLRAIRHLEKGRVVIFGAGLGAPFFSTDTTAAQRALEIKAQAVLKAT
HHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KVDGVYDSDPATNAGAVRFDSLTYSEVLARGLKVMDATAISLCMDNDLPIVVFDLLTEGN
HCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCC
ISRAVRGEKIGTLVGVETYGTEGTR
HHHHHCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
TDDADSAVGGVDPAARTEPGPRWTRLLLKLSGEAFAGGEPLGIDPVTLATIARQIAQVS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RSGIEVAIVVGAGNMFRGQALAERGMDRARADYMGMLGTVINCLALQDVLEREGIVTRVQ
HCCCEEEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
TAIAMGQVAEPYLPLRAIRHLEKGRVVIFGAGLGAPFFSTDTTAAQRALEIKAQAVLKAT
HHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KVDGVYDSDPATNAGAVRFDSLTYSEVLARGLKVMDATAISLCMDNDLPIVVFDLLTEGN
HCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCC
ISRAVRGEKIGTLVGVETYGTEGTR
HHHHHCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA