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The map label for this gene is lepB [H]

Identifier: 158313005

GI number: 158313005

Start: 1375081

End: 1376385

Strand: Direct

Name: lepB [H]

Synonym: Franean1_1153

Alternate gene names: 158313005

Gene position: 1375081-1376385 (Clockwise)

Preceding gene: 158313004

Following gene: 158313006

Centisome position: 15.31

GC content: 74.56

Gene sequence:

>1305_bases
GTGAGTGGATCGGACCGGGGCACGCCCGAGCCGTTCGGTGGTCAGGCGCAGGGCGGTCCGCCGTCCGGCGGCCCGGCCTC
AGGCGCTGCGGCGGGTGGTCACGGGCAGCGCGGTGACGCGGTTCTCCCCTGGGACACCGGCACCGACGTCTCGGACTCCC
GGCACGCTGCGGATTCCGGCCTGGCCGATTCCGGGCCGGCCTCGGACACCCGCGGCCGGGACGAGCGCGGTGACCTGACG
GGGCCCGGCGGCCTGCCGGGCGACGCCGTGCACCCGCCGGACGGGCCTACCGGGACGGCCGGGCACGAGGGCGCGGCCGG
GGGCGGTGAGCCCGCGGCGACGGGCCGACGGATCTCGCGCCCGCAGGCGGGGCGGGACCGCGGGCGCGGCTCCTTCCTGC
GCGAGCTGCCGATCCTGGTGCTGGTCGCGTTCCTGCTGGCGCTGCTGATCAAGACCGTGTTCGTCCAGGCGTTCTGGATT
CCGTCCGAGTCGATGGAGCGGACGCTGCTCATCGACGACCGGGTCCTGGTGAACAAGGTCATCTACCATTTCCGGGACGT
GCACCGGGGCGAGATCGTCGTGTTCAACGGCGAGGGCACCGGTTTCGAGCGGGAATCGATCGTGGCCCCGCCGGCCAACG
GCCTGAGCAGGTTCATCCGCGGCGCACAGGAGCTGCTGGGCCTCGGCGCGCCGAGCGAGAAGGACTTCATCAAGCGGGTG
ATCGGCGTAGGCGGTGACGTCGTCGCGTGCTGCGACGCCGCCGGGCGGGTGACGGTGAACGGCAAGGCGCTGGACGAGCC
GTACGTCTACGAGAACGACTTCCAGGCGTTCGGGCCGTTCACGGTCCCAGACGGGGACCTGTGGCTGATGGGCGATCACC
GCTCTCGCTCGTCGGATTCCCGCCAGAACGGCCCGGTCCCGCAGGACAAGGTGATCGGCCGGGCGTTCGTGCGGGTGTGG
CCGCTCGGCCGGTTCGGCCTGCTCACGGTGCCCGGCACGTTCTCCGGCATCCCATCGGCCTCCGCCGCGCCTGCTCGGAC
GCCCGCTCCGACGTCCGACGAGACGGCACCGAGTTCGCCGCCGGGCGCGGTCGGCGTGCCCGGAAGCACCGGATCCGCGG
ATCTGCTGATCGCCCCGGTCGGCGCGCTCGCCCTCGCCGTTCCGGCGAGCCGGCGGCGGCGCTCGGGCGGGCGGCGCTCG
ACCGGCGGGCGGTCCATCGGCTGGTCGACGCGGGCGAGCGGGGAGCGGCGCTGCGGCCCGCGCGGGCGGTGGGCGAGACG
GCGCGGTATGGGCGGTTCACCCTGA

Upstream 100 bases:

>100_bases
CAGGATGGTCAGGTCGTGGGTCGAACCGGTCAGGCCACGGCCATGGGCGGGTGTCGACCCGTTCCGTGACGAATGACGGC
CGACCTCGCGAGGTGGCGCA

Downstream 100 bases:

>100_bases
TCGCGATGGACGTGCGTGGCACGGCGATCCGCTCCGATGCCGGCCTCTTCGGCTACGAACGGGCGCTCGTCCGGCGCGGG
CTCGGGCCGGTCGCGGGTGT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSGSDRGTPEPFGGQAQGGPPSGGPASGAAAGGHGQRGDAVLPWDTGTDVSDSRHAADSGLADSGPASDTRGRDERGDLT
GPGGLPGDAVHPPDGPTGTAGHEGAAGGGEPAATGRRISRPQAGRDRGRGSFLRELPILVLVAFLLALLIKTVFVQAFWI
PSESMERTLLIDDRVLVNKVIYHFRDVHRGEIVVFNGEGTGFERESIVAPPANGLSRFIRGAQELLGLGAPSEKDFIKRV
IGVGGDVVACCDAAGRVTVNGKALDEPYVYENDFQAFGPFTVPDGDLWLMGDHRSRSSDSRQNGPVPQDKVIGRAFVRVW
PLGRFGLLTVPGTFSGIPSASAAPARTPAPTSDETAPSSPPGAVGVPGSTGSADLLIAPVGALALAVPASRRRRSGGRRS
TGGRSIGWSTRASGERRCGPRGRWARRRGMGGSP

Sequences:

>Translated_434_residues
MSGSDRGTPEPFGGQAQGGPPSGGPASGAAAGGHGQRGDAVLPWDTGTDVSDSRHAADSGLADSGPASDTRGRDERGDLT
GPGGLPGDAVHPPDGPTGTAGHEGAAGGGEPAATGRRISRPQAGRDRGRGSFLRELPILVLVAFLLALLIKTVFVQAFWI
PSESMERTLLIDDRVLVNKVIYHFRDVHRGEIVVFNGEGTGFERESIVAPPANGLSRFIRGAQELLGLGAPSEKDFIKRV
IGVGGDVVACCDAAGRVTVNGKALDEPYVYENDFQAFGPFTVPDGDLWLMGDHRSRSSDSRQNGPVPQDKVIGRAFVRVW
PLGRFGLLTVPGTFSGIPSASAAPARTPAPTSDETAPSSPPGAVGVPGSTGSADLLIAPVGALALAVPASRRRRSGGRRS
TGGRSIGWSTRASGERRCGPRGRWARRRGMGGSP
>Mature_433_residues
SGSDRGTPEPFGGQAQGGPPSGGPASGAAAGGHGQRGDAVLPWDTGTDVSDSRHAADSGLADSGPASDTRGRDERGDLTG
PGGLPGDAVHPPDGPTGTAGHEGAAGGGEPAATGRRISRPQAGRDRGRGSFLRELPILVLVAFLLALLIKTVFVQAFWIP
SESMERTLLIDDRVLVNKVIYHFRDVHRGEIVVFNGEGTGFERESIVAPPANGLSRFIRGAQELLGLGAPSEKDFIKRVI
GVGGDVVACCDAAGRVTVNGKALDEPYVYENDFQAFGPFTVPDGDLWLMGDHRSRSSDSRQNGPVPQDKVIGRAFVRVWP
LGRFGLLTVPGTFSGIPSASAAPARTPAPTSDETAPSSPPGAVGVPGSTGSADLLIAPVGALALAVPASRRRRSGGRRST
GGRSIGWSTRASGERRCGPRGRWARRRGMGGSP

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 44834; Mature: 44702

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSDRGTPEPFGGQAQGGPPSGGPASGAAAGGHGQRGDAVLPWDTGTDVSDSRHAADSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHCC
LADSGPASDTRGRDERGDLTGPGGLPGDAVHPPDGPTGTAGHEGAAGGGEPAATGRRISR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PQAGRDRGRGSFLRELPILVLVAFLLALLIKTVFVQAFWIPSESMERTLLIDDRVLVNKV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEECCHHHHHHH
IYHFRDVHRGEIVVFNGEGTGFERESIVAPPANGLSRFIRGAQELLGLGAPSEKDFIKRV
HHHHHHCCCCEEEEECCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IGVGGDVVACCDAAGRVTVNGKALDEPYVYENDFQAFGPFTVPDGDLWLMGDHRSRSSDS
HHCCCCEEEEECCCCEEEECCCCCCCCCEECCCCHHCCCEECCCCCEEEEECCCCCCCCC
RQNGPVPQDKVIGRAFVRVWPLGRFGLLTVPGTFSGIPSASAAPARTPAPTSDETAPSSP
CCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PGAVGVPGSTGSADLLIAPVGALALAVPASRRRRSGGRRSTGGRSIGWSTRASGERRCGP
CCCEECCCCCCCCCEEEECHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
RGRWARRRGMGGSP
CCHHHHHCCCCCCC
>Mature Secondary Structure 
SGSDRGTPEPFGGQAQGGPPSGGPASGAAAGGHGQRGDAVLPWDTGTDVSDSRHAADSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHCC
LADSGPASDTRGRDERGDLTGPGGLPGDAVHPPDGPTGTAGHEGAAGGGEPAATGRRISR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PQAGRDRGRGSFLRELPILVLVAFLLALLIKTVFVQAFWIPSESMERTLLIDDRVLVNKV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEECCHHHHHHH
IYHFRDVHRGEIVVFNGEGTGFERESIVAPPANGLSRFIRGAQELLGLGAPSEKDFIKRV
HHHHHHCCCCEEEEECCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IGVGGDVVACCDAAGRVTVNGKALDEPYVYENDFQAFGPFTVPDGDLWLMGDHRSRSSDS
HHCCCCEEEEECCCCEEEECCCCCCCCCEECCCCHHCCCEECCCCCEEEEECCCCCCCCC
RQNGPVPQDKVIGRAFVRVWPLGRFGLLTVPGTFSGIPSASAAPARTPAPTSDETAPSSP
CCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PGAVGVPGSTGSADLLIAPVGALALAVPASRRRRSGGRRSTGGRSIGWSTRASGERRCGP
CCCEECCCCCCCCCEEEECHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
RGRWARRRGMGGSP
CCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]