Click here to switch to the map view.

The map label for this gene is ffh [H]

Identifier: 158312999

GI number: 158312999

Start: 1369759

End: 1371324

Strand: Direct

Name: ffh [H]

Synonym: Franean1_1147

Alternate gene names: 158312999

Gene position: 1369759-1371324 (Clockwise)

Preceding gene: 158312998

Following gene: 158313000

Centisome position: 15.25

GC content: 72.29

Gene sequence:

>1566_bases
GTGTTCGACACCCTTTCCAGCCGCCTCGACAAGGTCTTCACGTCGCTGCGTGGCAGGGGGCGGCTGACCGACGCCGACAT
CGACGCCACCGCCCGTGAGATCAGGGTGGCGCTGCTGGAGGCCGACGTCGCGCTGCCGGTCGTCCGCGGTTTCGTCGCCG
CCATCCGCGAGCGGGCCCGCGGGGCCGAGGTGAGCACCTCGCTCAACCCGGCGCAGCAGGTCATCAAGATCGTCAACGAG
GAGCTCGTCGCCATTCTCGGCGGCGGCACGACCACGTTGCGCTTCGCCAAGACGCCGCCGACCGTGATCCTGCTCGCCGG
CCTGCAGGGAACCGGCAAGACGACCCTCGCCGGCAAGCTCGGCCGCTGGCTGCGAGCCCAGGGGCACACGCCGCTGCTCG
TCGCCGCCGACCTGCAGCGCCCGAACGCGGTGAACCAGCTCCAGGTCGTCGGCCAGCGGGCCGGGGTCGAGGTCTTCGCC
CCGGAGCCCGGCAACGGTGTCGGTGACCCGGTGCGGGTCGCCCGCGACGCGCTCGCCCACGCCCGTCGCCACGTCTTCGA
CGTGGTGGTCGTCGACACGGCCGGCCGCCTCGGTGTCGACGAGGAGCTGATGCGCCAGGCCGCCGACATCCGCGACGCCG
TCTCGCCGGACGAGATCCTCTTCGTCCTCGACGCGATGATCGGCCAGGACGCCGTCTCCACGGCCCAGGCCTTCGCTGAC
GGGGTCGGCTTCACCGGCGTCGTGCTGACCAAGCTTGACGGTGACGCGCGCGGTGGTGCCGCGCTGTCGGTGGCCCGGGT
GACCGGGGCGCCGATCATGTTCGCCTCCACCGGCGAGACGCTCGACGACTTCGACGTCTTCCACCCCGAGCGGATGGCCT
CGCGCATCCTCGGTATGGGCGACGTCCTGACGCTCATCGAGCAGGCCGAGAAGGCGTTCGAGGTCGAGCAGGCCGAGGCG
ATGGCCGTCAAGATGGCCAACTCGGAGTTCACGCTCGAGGACTTTCTCGAGCAGATGCTCACCGTTCGCAAGATGGGCCC
GATCGGCAACCTGCTCGGGATGCTGCCCGGAATGGGGCAGATCAAGGACCAGCTCGCCCAGGTTGACGACCGCGACCTCG
ACCGGGTCGTCGCCATCATCCGGTCCATGACGCCGGCCGAGCGGCGGGACCCGAAGATCCTCCAGGCTTCCCGCAAGGCC
CGGGTGGCGCGCGGGTCCGGCGTGACCGTCACCGAGGTCAACCAACTGCTGGACCGCTTCGGTGAGGCGCGCAAGATGAT
GCGGCAGATGGCCGGCGGCGCCGGCCTGCCGGCGGGAATGGCACGCGCGAAGGCGGCCCAGGCCCGCAAGGCCGCCAAGA
AGGGCAAGGGCGCGCGGCGCAGCGGAAACCCGGCGGCGCGCGCCGCGCAGGCGCAGGACCGCCGCAACGCGCCCCAGGAC
GGCCCGCCGGCGCTCGGCCTTGGGGGCGACGGCCTGCAGGGCATGCCTGACCTGTCCTCGCTCATCCAGCAGGGTGGCTT
CGGGGGCGGCGACACCCCGCCGCGGCGTCCCCGCCCAGGCCGCTGA

Upstream 100 bases:

>100_bases
CCACGGCGGGCCTCACGTCGTCACGGGTCCTGGTTCCGGATCGGCGCGGGGTGCGTACGCTGGTGCCTGCGGTCCGTCTG
CGATCTCGGAGTGTGTGCGC

Downstream 100 bases:

>100_bases
CCCGCGCGAACCCACCCGCCCGGCGGGGGCCCTGGCGAAGACCCGGGTGCCCCGGGCGTTGCGTCGGCAGGTGATCTGGC
AGACTGTAAGGTCATACAGG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MFDTLSSRLDKVFTSLRGRGRLTDADIDATAREIRVALLEADVALPVVRGFVAAIRERARGAEVSTSLNPAQQVIKIVNE
ELVAILGGGTTTLRFAKTPPTVILLAGLQGTGKTTLAGKLGRWLRAQGHTPLLVAADLQRPNAVNQLQVVGQRAGVEVFA
PEPGNGVGDPVRVARDALAHARRHVFDVVVVDTAGRLGVDEELMRQAADIRDAVSPDEILFVLDAMIGQDAVSTAQAFAD
GVGFTGVVLTKLDGDARGGAALSVARVTGAPIMFASTGETLDDFDVFHPERMASRILGMGDVLTLIEQAEKAFEVEQAEA
MAVKMANSEFTLEDFLEQMLTVRKMGPIGNLLGMLPGMGQIKDQLAQVDDRDLDRVVAIIRSMTPAERRDPKILQASRKA
RVARGSGVTVTEVNQLLDRFGEARKMMRQMAGGAGLPAGMARAKAAQARKAAKKGKGARRSGNPAARAAQAQDRRNAPQD
GPPALGLGGDGLQGMPDLSSLIQQGGFGGGDTPPRRPRPGR

Sequences:

>Translated_521_residues
MFDTLSSRLDKVFTSLRGRGRLTDADIDATAREIRVALLEADVALPVVRGFVAAIRERARGAEVSTSLNPAQQVIKIVNE
ELVAILGGGTTTLRFAKTPPTVILLAGLQGTGKTTLAGKLGRWLRAQGHTPLLVAADLQRPNAVNQLQVVGQRAGVEVFA
PEPGNGVGDPVRVARDALAHARRHVFDVVVVDTAGRLGVDEELMRQAADIRDAVSPDEILFVLDAMIGQDAVSTAQAFAD
GVGFTGVVLTKLDGDARGGAALSVARVTGAPIMFASTGETLDDFDVFHPERMASRILGMGDVLTLIEQAEKAFEVEQAEA
MAVKMANSEFTLEDFLEQMLTVRKMGPIGNLLGMLPGMGQIKDQLAQVDDRDLDRVVAIIRSMTPAERRDPKILQASRKA
RVARGSGVTVTEVNQLLDRFGEARKMMRQMAGGAGLPAGMARAKAAQARKAAKKGKGARRSGNPAARAAQAQDRRNAPQD
GPPALGLGGDGLQGMPDLSSLIQQGGFGGGDTPPRRPRPGR
>Mature_521_residues
MFDTLSSRLDKVFTSLRGRGRLTDADIDATAREIRVALLEADVALPVVRGFVAAIRERARGAEVSTSLNPAQQVIKIVNE
ELVAILGGGTTTLRFAKTPPTVILLAGLQGTGKTTLAGKLGRWLRAQGHTPLLVAADLQRPNAVNQLQVVGQRAGVEVFA
PEPGNGVGDPVRVARDALAHARRHVFDVVVVDTAGRLGVDEELMRQAADIRDAVSPDEILFVLDAMIGQDAVSTAQAFAD
GVGFTGVVLTKLDGDARGGAALSVARVTGAPIMFASTGETLDDFDVFHPERMASRILGMGDVLTLIEQAEKAFEVEQAEA
MAVKMANSEFTLEDFLEQMLTVRKMGPIGNLLGMLPGMGQIKDQLAQVDDRDLDRVVAIIRSMTPAERRDPKILQASRKA
RVARGSGVTVTEVNQLLDRFGEARKMMRQMAGGAGLPAGMARAKAAQARKAAKKGKGARRSGNPAARAAQAQDRRNAPQD
GPPALGLGGDGLQGMPDLSSLIQQGGFGGGDTPPRRPRPGR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=462, Percent_Identity=32.6839826839827, Blast_Score=249, Evalue=6e-66,
Organism=Homo sapiens, GI226371618, Length=400, Percent_Identity=33.75, Blast_Score=231, Evalue=9e-61,
Organism=Homo sapiens, GI89061728, Length=157, Percent_Identity=38.2165605095541, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI23308697, Length=300, Percent_Identity=30.6666666666667, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI295424842, Length=300, Percent_Identity=30.6666666666667, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI1788963, Length=428, Percent_Identity=49.5327102803738, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1789874, Length=253, Percent_Identity=37.9446640316205, Blast_Score=146, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17539958, Length=451, Percent_Identity=29.9334811529933, Blast_Score=231, Evalue=9e-61,
Organism=Caenorhabditis elegans, GI193206261, Length=292, Percent_Identity=32.5342465753425, Blast_Score=113, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6325345, Length=432, Percent_Identity=33.5648148148148, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6320498, Length=215, Percent_Identity=31.6279069767442, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17647949, Length=441, Percent_Identity=31.7460317460317, Blast_Score=218, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24641198, Length=304, Percent_Identity=30.2631578947368, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 55166; Mature: 55166

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTLSSRLDKVFTSLRGRGRLTDADIDATAREIRVALLEADVALPVVRGFVAAIRERAR
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAEVSTSLNPAQQVIKIVNEELVAILGGGTTTLRFAKTPPTVILLAGLQGTGKTTLAGKL
CCCCCCCCCHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCEEEEECCCCCCCHHHHHHH
GRWLRAQGHTPLLVAADLQRPNAVNQLQVVGQRAGVEVFAPEPGNGVGDPVRVARDALAH
HHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHH
ARRHVFDVVVVDTAGRLGVDEELMRQAADIRDAVSPDEILFVLDAMIGQDAVSTAQAFAD
HHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHC
GVGFTGVVLTKLDGDARGGAALSVARVTGAPIMFASTGETLDDFDVFHPERMASRILGMG
CCCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHCCCHHHHHHHHHCCH
DVLTLIEQAEKAFEVEQAEAMAVKMANSEFTLEDFLEQMLTVRKMGPIGNLLGMLPGMGQ
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHH
IKDQLAQVDDRDLDRVVAIIRSMTPAERRDPKILQASRKARVARGSGVTVTEVNQLLDRF
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GEARKMMRQMAGGAGLPAGMARAKAAQARKAAKKGKGARRSGNPAARAAQAQDRRNAPQD
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
GPPALGLGGDGLQGMPDLSSLIQQGGFGGGDTPPRRPRPGR
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDTLSSRLDKVFTSLRGRGRLTDADIDATAREIRVALLEADVALPVVRGFVAAIRERAR
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAEVSTSLNPAQQVIKIVNEELVAILGGGTTTLRFAKTPPTVILLAGLQGTGKTTLAGKL
CCCCCCCCCHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCEEEEECCCCCCCHHHHHHH
GRWLRAQGHTPLLVAADLQRPNAVNQLQVVGQRAGVEVFAPEPGNGVGDPVRVARDALAH
HHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHH
ARRHVFDVVVVDTAGRLGVDEELMRQAADIRDAVSPDEILFVLDAMIGQDAVSTAQAFAD
HHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHC
GVGFTGVVLTKLDGDARGGAALSVARVTGAPIMFASTGETLDDFDVFHPERMASRILGMG
CCCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHCCCHHHHHHHHHCCH
DVLTLIEQAEKAFEVEQAEAMAVKMANSEFTLEDFLEQMLTVRKMGPIGNLLGMLPGMGQ
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHH
IKDQLAQVDDRDLDRVVAIIRSMTPAERRDPKILQASRKARVARGSGVTVTEVNQLLDRF
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GEARKMMRQMAGGAGLPAGMARAKAAQARKAAKKGKGARRSGNPAARAAQAQDRRNAPQD
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
GPPALGLGGDGLQGMPDLSSLIQQGGFGGGDTPPRRPRPGR
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]