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The map label for this gene is ilvE [H]

Identifier: 158312953

GI number: 158312953

Start: 1313143

End: 1314066

Strand: Direct

Name: ilvE [H]

Synonym: Franean1_1099

Alternate gene names: 158312953

Gene position: 1313143-1314066 (Clockwise)

Preceding gene: 158312952

Following gene: 158312954

Centisome position: 14.62

GC content: 67.86

Gene sequence:

>924_bases
ATGGCCATCACGCCCACCTCGAAGATCTGGATGAGCGGCGAGTTCGTCGACTGGGACGACGCCCGCATCCACGTGCTCAA
CCCGACCCTGCACTACGGCTGGGGCGTGTTCGAGGGCATCCGTGCCTACTCGACGCCCGTCGGCAGCGCGGTCTTCCGGC
TGACCGACCACATCGCCCGCCTGTACCGCAGCGCGAAGATCTACCTGATGGAGCCGACCTTCACGCCGGAGGAGCTTGTC
CAGGCGACGAAGGACACCATCGCGGTGAACAACGTCGAGGAGTGCTACATCCGGCCCCTGATCTACCTCGGGTACGGCGA
GATGGGCCTCAATCCGCTCCCGTCCTCGATCGAGGTCATGATCGCGGTCTGGCCCTGGGGCTCCTACCTGGGCGAGGACG
CCGAGCGCAACGGGGCTCGGGCGACGATCTCGACCTGGCGCCGCAACGACCCGAACATCATCCCGCCGGCCGCAAAGGCG
TCCGGCCAGTACCTCAACTCGTCGCTCGCCAAGGTCGCCGCGATCAAGGCCGGTTACGACGAGGCGATCATGACCAGCCC
GAACGGCCACATCGCTGACGGCTCCGGCGAGAACGTCTTCATTGTCTCCGGCCGGCAGGTGATCACCCCGCCGCTCAGCG
ACGGGCCGCTCGGCGGCATCACCCGCGCCTCCGTCATGCAGATCGCCGCGGACCAGGGCTACGAGGTGCGCGAGCAGCAC
ATCGTGCGCACCGACCTCTACCTCGCCGACGAGGCGTTCTTCACCGGCACCGCGGCCGAGATCGTTCCCATCTCCGAGGT
GGACGACCGGCGGATCGGCGCGGGCCGGCCCGGCCCGGTCACCCGGGAGATCCTCGACATCTTCCACCAGGCCACCCACG
GCGAGGTCGACCGCTACAAGGACTGGAACGAGCTCGTCAGCTGA

Upstream 100 bases:

>100_bases
CGAGCGCCGGTCAGTGACAGCGTTCGCGCACCGCGGCGCTCGTGCCCGCGGTGCTCGCCAGCCCGCACGTCCCCCTGACG
TAGCCCGTCCTGGAGTCATC

Downstream 100 bases:

>100_bases
CGTCCCGCCCGGCGGCGAGCCGACTGCGTGACCACGCCGCCGCCGCGTGTGCCCTGGCCAACCCGACCTTGGACGCCTAC
CGTCTCCAGTAGTCGTTTCA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MAITPTSKIWMSGEFVDWDDARIHVLNPTLHYGWGVFEGIRAYSTPVGSAVFRLTDHIARLYRSAKIYLMEPTFTPEELV
QATKDTIAVNNVEECYIRPLIYLGYGEMGLNPLPSSIEVMIAVWPWGSYLGEDAERNGARATISTWRRNDPNIIPPAAKA
SGQYLNSSLAKVAAIKAGYDEAIMTSPNGHIADGSGENVFIVSGRQVITPPLSDGPLGGITRASVMQIAADQGYEVREQH
IVRTDLYLADEAFFTGTAAEIVPISEVDDRRIGAGRPGPVTREILDIFHQATHGEVDRYKDWNELVS

Sequences:

>Translated_307_residues
MAITPTSKIWMSGEFVDWDDARIHVLNPTLHYGWGVFEGIRAYSTPVGSAVFRLTDHIARLYRSAKIYLMEPTFTPEELV
QATKDTIAVNNVEECYIRPLIYLGYGEMGLNPLPSSIEVMIAVWPWGSYLGEDAERNGARATISTWRRNDPNIIPPAAKA
SGQYLNSSLAKVAAIKAGYDEAIMTSPNGHIADGSGENVFIVSGRQVITPPLSDGPLGGITRASVMQIAADQGYEVREQH
IVRTDLYLADEAFFTGTAAEIVPISEVDDRRIGAGRPGPVTREILDIFHQATHGEVDRYKDWNELVS
>Mature_306_residues
AITPTSKIWMSGEFVDWDDARIHVLNPTLHYGWGVFEGIRAYSTPVGSAVFRLTDHIARLYRSAKIYLMEPTFTPEELVQ
ATKDTIAVNNVEECYIRPLIYLGYGEMGLNPLPSSIEVMIAVWPWGSYLGEDAERNGARATISTWRRNDPNIIPPAAKAS
GQYLNSSLAKVAAIKAGYDEAIMTSPNGHIADGSGENVFIVSGRQVITPPLSDGPLGGITRASVMQIAADQGYEVREQHI
VRTDLYLADEAFFTGTAAEIVPISEVDDRRIGAGRPGPVTREILDIFHQATHGEVDRYKDWNELVS

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=308, Percent_Identity=45.4545454545455, Blast_Score=272, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322002, Length=310, Percent_Identity=26.4516129032258, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 33825; Mature: 33693

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITPTSKIWMSGEFVDWDDARIHVLNPTLHYGWGVFEGIRAYSTPVGSAVFRLTDHIAR
CCCCCCCCEEECCCEECCCCCEEEEECCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LYRSAKIYLMEPTFTPEELVQATKDTIAVNNVEECYIRPLIYLGYGEMGLNPLPSSIEVM
HHHCCEEEEECCCCCHHHHHHHHHHHEEECCHHHHHHCEEEEEECCCCCCCCCCCCEEEE
IAVWPWGSYLGEDAERNGARATISTWRRNDPNIIPPAAKASGQYLNSSLAKVAAIKAGYD
EEEECCHHHHCCCHHCCCCEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
EAIMTSPNGHIADGSGENVFIVSGRQVITPPLSDGPLGGITRASVMQIAADQGYEVREQH
CEEEECCCCCEECCCCCEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
IVRTDLYLADEAFFTGTAAEIVPISEVDDRRIGAGRPGPVTREILDIFHQATHGEVDRYK
HHHHHEEEECCCEECCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHCC
DWNELVS
CHHHHCC
>Mature Secondary Structure 
AITPTSKIWMSGEFVDWDDARIHVLNPTLHYGWGVFEGIRAYSTPVGSAVFRLTDHIAR
CCCCCCCEEECCCEECCCCCEEEEECCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LYRSAKIYLMEPTFTPEELVQATKDTIAVNNVEECYIRPLIYLGYGEMGLNPLPSSIEVM
HHHCCEEEEECCCCCHHHHHHHHHHHEEECCHHHHHHCEEEEEECCCCCCCCCCCCEEEE
IAVWPWGSYLGEDAERNGARATISTWRRNDPNIIPPAAKASGQYLNSSLAKVAAIKAGYD
EEEECCHHHHCCCHHCCCCEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
EAIMTSPNGHIADGSGENVFIVSGRQVITPPLSDGPLGGITRASVMQIAADQGYEVREQH
CEEEECCCCCEECCCCCEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
IVRTDLYLADEAFFTGTAAEIVPISEVDDRRIGAGRPGPVTREILDIFHQATHGEVDRYK
HHHHHEEEECCCEECCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHCC
DWNELVS
CHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]