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The map label for this gene is atpA

Identifier: 158312876

GI number: 158312876

Start: 1201863

End: 1203524

Strand: Direct

Name: atpA

Synonym: Franean1_1022

Alternate gene names: 158312876

Gene position: 1201863-1203524 (Clockwise)

Preceding gene: 158312875

Following gene: 158312877

Centisome position: 13.38

GC content: 69.01

Gene sequence:

>1662_bases
ATGACTGAGCTGTCCATCCGGCCGGAGGAGATCCGCGACGCCCTCCGGGAGTACGTCGACTCCTTCCAGGCCACCTCCGG
TGACCGGGAGGAGGTCGGCCGTGTCGTCGTGACCGGTGACGGGATCGCGCGGGTCGAGGGCCTTCCGCACACCATGACCA
ACGAGCTGCTGGAGTTCTCCGGCGGTGTGCTGGGACTGGCCCTCAACCTCGAGGTCGGCGAGATCGGCTGCGTCATCCTC
GGCGACGCCGAGCACATCGAGGAGGGCCAGGAGGTCCGCCGGACCGGCGAGATCCTCGCCGTCCCGGTGGGCGACGGCTT
CCTCGGCCGGGTCGTCGACCCGCTCGGGCGCCCGATCGACGGCCTCGGTGACATCGCCGCGGCCGGCACCCGGGCGCTCG
AGCTGCAGGCCCCGTCTGTGGTGCAGCGCCAGCCCGTCAAGGAGCCGCTGCAGACCGGCATCAAGGCCATCGACGCGATG
ACCGCCATCGGCCGGGGTCAGCGTCAGCTGATCATCGGCGACCGGCAGACCGGGAAGACCACCGTCGCGATCGACGCGAT
CATCAACCAGCGTGACAACTGGGCGAGCGGTGACCCGAAGAAGCAGGTCAAGTGCGTCTACGTGGCCATCGGCCAGAAGA
AGACGACCATCCGCGAGGTGGTGAACACCCTCGAGGAGGCCGGCGCGCTGGCCTACACGACGATCGTCGCCGCCCCGGCC
GACCAGCCGGCGGGCTTCAAGTACATCGCCCCGTACACCGGCTCGGCGATCGGGCAGTACTGGATGTACAACGGCCAGCA
CTCGCTGGTGGTCTTCGACGACCTCTCCAAGCAGGCCGAGGCGTACCGCGCGATCTCGCTGCTGCTTCGCCGCCCGCCGG
GCCGTGAGGCATACCCGGGCGACGTCTTCTACTTGCACTCCCGTCTGCTGGAGCGCTGCGCGAAGCTCTCCGACGAGCTC
GGGGGCGGGTCGCTGACCGGGCTGCCGATCATCGAGACCAAGGCCAACGACATCTCGGCCTACATCCCGACGAACGTCAT
CTCGATCACCGACGGCCAGATCTTCCTGGAGTCGGACCTGTTCAACCAGGGCGTCCGCCCGGCGATCAACGTCGGTACCT
CGGTCTCCCGAGTGGGCGGCAGCGCGCAGGTCAAGGCGATGAAGTCCGTCGCCGGCCGCCTGCGCCTCGACCTGGCCCAG
TACCGCGAGCTGGAGGCCTTCTCGGCCTTCGGCTCCGACCTGGACAAGGCCTCCCGCGACCAGCTCGCCCGCGGTGCCCG
GCTGGTGGAGCTGCTCAAGCAGCCCCAGAACAAGCCGTTCTCCGTCGAGCGCCAGGTCGTGTCGATCTGGGCCGGCACCA
CCGGCAAGCTGGACGACGTGCCGGTGGAGGACATCCGCCGCTTCGAGGCCGAGTTCCTCGACTTCGTCGGGCGGACCCAC
GGCGCCATCTACGACACCATCGTGAACACCGGGAAGCTCGGTGACGACCTCGTCTCCTCCCTGGAGTCGGCCATCGCCGA
GTTCAAGGAGCAGTTCACGCTGTCGAGCGGCAAGCAGCTGGTGAACGAGGCGGCTCCCGAGGCGCTCGACCCGTCCGCGG
TGGAGCGCGAGGAGATCGCCGTCCACCACCGCAAGCCGTCCGACGAGACCGCGGGTCACTGA

Upstream 100 bases:

>100_bases
GGCCGCGGAGCGCGATGGGTGAGCTGAAGCCGGGACCGATCCCAGAACCGGCAGAGACGACCGATGACCAGATCCACGCC
AGCCATGAAGGACCAACGCG

Downstream 100 bases:

>100_bases
CCCATGGCAGGCCAGCTTCGCGAATATCGGCGGCGGATCAAGACGGTCCAGTCCACCAAGAAGATCACCAAGGCGATGGA
GCTCATCGCCGCCTCGCGGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTELSIRPEEIRDALREYVDSFQATSGDREEVGRVVVTGDGIARVEGLPHTMTNELLEFSGGVLGLALNLEVGEIGCVIL
GDAEHIEEGQEVRRTGEILAVPVGDGFLGRVVDPLGRPIDGLGDIAAAGTRALELQAPSVVQRQPVKEPLQTGIKAIDAM
TAIGRGQRQLIIGDRQTGKTTVAIDAIINQRDNWASGDPKKQVKCVYVAIGQKKTTIREVVNTLEEAGALAYTTIVAAPA
DQPAGFKYIAPYTGSAIGQYWMYNGQHSLVVFDDLSKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDEL
GGGSLTGLPIIETKANDISAYIPTNVISITDGQIFLESDLFNQGVRPAINVGTSVSRVGGSAQVKAMKSVAGRLRLDLAQ
YRELEAFSAFGSDLDKASRDQLARGARLVELLKQPQNKPFSVERQVVSIWAGTTGKLDDVPVEDIRRFEAEFLDFVGRTH
GAIYDTIVNTGKLGDDLVSSLESAIAEFKEQFTLSSGKQLVNEAAPEALDPSAVEREEIAVHHRKPSDETAGH

Sequences:

>Translated_553_residues
MTELSIRPEEIRDALREYVDSFQATSGDREEVGRVVVTGDGIARVEGLPHTMTNELLEFSGGVLGLALNLEVGEIGCVIL
GDAEHIEEGQEVRRTGEILAVPVGDGFLGRVVDPLGRPIDGLGDIAAAGTRALELQAPSVVQRQPVKEPLQTGIKAIDAM
TAIGRGQRQLIIGDRQTGKTTVAIDAIINQRDNWASGDPKKQVKCVYVAIGQKKTTIREVVNTLEEAGALAYTTIVAAPA
DQPAGFKYIAPYTGSAIGQYWMYNGQHSLVVFDDLSKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDEL
GGGSLTGLPIIETKANDISAYIPTNVISITDGQIFLESDLFNQGVRPAINVGTSVSRVGGSAQVKAMKSVAGRLRLDLAQ
YRELEAFSAFGSDLDKASRDQLARGARLVELLKQPQNKPFSVERQVVSIWAGTTGKLDDVPVEDIRRFEAEFLDFVGRTH
GAIYDTIVNTGKLGDDLVSSLESAIAEFKEQFTLSSGKQLVNEAAPEALDPSAVEREEIAVHHRKPSDETAGH
>Mature_552_residues
TELSIRPEEIRDALREYVDSFQATSGDREEVGRVVVTGDGIARVEGLPHTMTNELLEFSGGVLGLALNLEVGEIGCVILG
DAEHIEEGQEVRRTGEILAVPVGDGFLGRVVDPLGRPIDGLGDIAAAGTRALELQAPSVVQRQPVKEPLQTGIKAIDAMT
AIGRGQRQLIIGDRQTGKTTVAIDAIINQRDNWASGDPKKQVKCVYVAIGQKKTTIREVVNTLEEAGALAYTTIVAAPAD
QPAGFKYIAPYTGSAIGQYWMYNGQHSLVVFDDLSKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDELG
GGSLTGLPIIETKANDISAYIPTNVISITDGQIFLESDLFNQGVRPAINVGTSVSRVGGSAQVKAMKSVAGRLRLDLAQY
RELEAFSAFGSDLDKASRDQLARGARLVELLKQPQNKPFSVERQVVSIWAGTTGKLDDVPVEDIRRFEAEFLDFVGRTHG
AIYDTIVNTGKLGDDLVSSLESAIAEFKEQFTLSSGKQLVNEAAPEALDPSAVEREEIAVHHRKPSDETAGH

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=488, Percent_Identity=56.3524590163934, Blast_Score=561, Evalue=1e-160,
Organism=Homo sapiens, GI4757810, Length=488, Percent_Identity=56.3524590163934, Blast_Score=561, Evalue=1e-160,
Organism=Homo sapiens, GI19913428, Length=302, Percent_Identity=30.794701986755, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI19913426, Length=302, Percent_Identity=30.4635761589404, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI32189394, Length=473, Percent_Identity=24.7357293868922, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1790172, Length=517, Percent_Identity=51.6441005802708, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1788251, Length=383, Percent_Identity=27.9373368146214, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790170, Length=401, Percent_Identity=23.4413965087282, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=483, Percent_Identity=56.5217391304348, Blast_Score=560, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988080, Length=483, Percent_Identity=56.5217391304348, Blast_Score=559, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI71988074, Length=483, Percent_Identity=52.1739130434783, Blast_Score=505, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17570191, Length=291, Percent_Identity=30.9278350515464, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=291, Percent_Identity=30.2405498281787, Blast_Score=118, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=402, Percent_Identity=24.8756218905473, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319370, Length=507, Percent_Identity=55.6213017751479, Blast_Score=567, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6319603, Length=305, Percent_Identity=31.4754098360656, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6322581, Length=418, Percent_Identity=24.8803827751196, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=54.7430830039526, Blast_Score=558, Evalue=1e-159,
Organism=Drosophila melanogaster, GI281361666, Length=303, Percent_Identity=30.6930693069307, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646341, Length=303, Percent_Identity=30.6930693069307, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17136796, Length=303, Percent_Identity=30.6930693069307, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24638766, Length=419, Percent_Identity=26.2529832935561, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28574560, Length=397, Percent_Identity=25.6926952141058, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_FRASN (A8L3W3)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001505384.1
- ProteinModelPortal:   A8L3W3
- SMR:   A8L3W3
- GeneID:   5669436
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_1022
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- BioCyc:   FSP1855:FRANEAN1_1022-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 59768; Mature: 59637

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELSIRPEEIRDALREYVDSFQATSGDREEVGRVVVTGDGIARVEGLPHTMTNELLEFS
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCEEEEECCCHHHHCCCCHHHHHHHHHHC
GGVLGLALNLEVGEIGCVILGDAEHIEEGQEVRRTGEILAVPVGDGFLGRVVDPLGRPID
CCEEEEEEEEEECCEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCC
GLGDIAAAGTRALELQAPSVVQRQPVKEPLQTGIKAIDAMTAIGRGQRQLIIGDRQTGKT
CHHHHHHCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCE
TVAIDAIINQRDNWASGDPKKQVKCVYVAIGQKKTTIREVVNTLEEAGALAYTTIVAAPA
EEEEEHHHCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCC
DQPAGFKYIAPYTGSAIGQYWMYNGQHSLVVFDDLSKQAEAYRAISLLLRRPPGREAYPG
CCCCCEEEECCCCCCHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCC
DVFYLHSRLLERCAKLSDELGGGSLTGLPIIETKANDISAYIPTNVISITDGQIFLESDL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCEEEEECCCEEEECHH
FNQGVRPAINVGTSVSRVGGSAQVKAMKSVAGRLRLDLAQYRELEAFSAFGSDLDKASRD
HCCCCCCHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QLARGARLVELLKQPQNKPFSVERQVVSIWAGTTGKLDDVPVEDIRRFEAEFLDFVGRTH
HHHHHHHHHHHHHCCCCCCCHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GAIYDTIVNTGKLGDDLVSSLESAIAEFKEQFTLSSGKQLVNEAAPEALDPSAVEREEIA
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCHHHHH
VHHRKPSDETAGH
HHCCCCCCCCCCC
>Mature Secondary Structure 
TELSIRPEEIRDALREYVDSFQATSGDREEVGRVVVTGDGIARVEGLPHTMTNELLEFS
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCEEEEECCCHHHHCCCCHHHHHHHHHHC
GGVLGLALNLEVGEIGCVILGDAEHIEEGQEVRRTGEILAVPVGDGFLGRVVDPLGRPID
CCEEEEEEEEEECCEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCC
GLGDIAAAGTRALELQAPSVVQRQPVKEPLQTGIKAIDAMTAIGRGQRQLIIGDRQTGKT
CHHHHHHCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCE
TVAIDAIINQRDNWASGDPKKQVKCVYVAIGQKKTTIREVVNTLEEAGALAYTTIVAAPA
EEEEEHHHCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCC
DQPAGFKYIAPYTGSAIGQYWMYNGQHSLVVFDDLSKQAEAYRAISLLLRRPPGREAYPG
CCCCCEEEECCCCCCHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCC
DVFYLHSRLLERCAKLSDELGGGSLTGLPIIETKANDISAYIPTNVISITDGQIFLESDL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCEEEEECCCEEEECHH
FNQGVRPAINVGTSVSRVGGSAQVKAMKSVAGRLRLDLAQYRELEAFSAFGSDLDKASRD
HCCCCCCHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QLARGARLVELLKQPQNKPFSVERQVVSIWAGTTGKLDDVPVEDIRRFEAEFLDFVGRTH
HHHHHHHHHHHHHCCCCCCCHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GAIYDTIVNTGKLGDDLVSSLESAIAEFKEQFTLSSGKQLVNEAAPEALDPSAVEREEIA
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCHHHHH
VHHRKPSDETAGH
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA