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The map label for this gene is mlc [C]

Identifier: 158312574

GI number: 158312574

Start: 835419

End: 836708

Strand: Direct

Name: mlc [C]

Synonym: Franean1_0718

Alternate gene names: 158312574

Gene position: 835419-836708 (Clockwise)

Preceding gene: 158312573

Following gene: 158312576

Centisome position: 9.3

GC content: 75.12

Gene sequence:

>1290_bases
GTGCCCATCCGGAGCGCGAACCCGCCCACCATCTCGCCGACCGGCCTCGCCGGGCCCGGAAACGATCGCAGGGACACCTC
GAAAGGCGCCGGATCGGCGGCGGCCGTGCTACGCGCCGTCCTCGATCACGGGCCCGTCGCGAGGGGGTTCATCGGCACCG
CGACGGGTCTCAGCCCGGCCGCGGTCTCACGGCAGACCGCCGACCTCATCTCGCTCGGGCTGCTGCGGGAGCTGCCGGTC
GCTGCCGGCGCGCCGCGGGCGGGGCGGCCGAGCGTGCCGCTCGACGTCGACACCGACACCCACCTCGCCTGCGGCGTGCA
CATCGCCGTCCCCATGCTCACCTTCGGAATCGTCGACCTGCGGGGCCGGGTGGTCGCCCGCGAGGAGTTGCCGCACCGGG
GCGAGGCCGACGACACGCTCTCGACCATCGTTCGGCACCTGCCCGGATTCCTGCGCCGGCACGCCGGCCACCGCCGGGTC
CTCGGACTCGGCGTGGTCACGGGCGGCCACGTCGACGCACGGACCGGCGTCGTGGTCGAACACGAGCCGCTGGGCTGGCG
GGACCTGCCGTTGGGCCCGCTGCTGGCCGCCCGCACCGGCCTCCCGGTGAGCGTGGACGGCCATGCCCGTGCGCTGGCTC
AGGCGGAGATCCTCTTCGGTGAGCCGCGGGCCCGGGCAAGCCTGGTGCACCTGTTCGTGGGCCATGTGGTGGACGCGGCC
ATAGCCACAGACGGAGTCGTGCATCACGGCCTTCGCTCGGCGGCGGGCGGGGTGGCGCACCTGAACCTGCCCGGGGCCGA
CCTGCCGTGCTCCTGCGGCGGCCGGGGCTGCGCCCAGACCGCGCTGTCGGACCGCGCGCTGCTCGTGAAGGCCGTCGAGC
TCGGAGCCATACCGCGACCGGAGGCCGAGCTCCTGCTGGGGGCGGCCCGTGCCGGCGACGACCTCGTGGTGGGACTGCTG
CGCCAACGGCTGCGGGGGGTCGCCAGGATCGCCGCGACGCTGCTCGACATGCTGGACCCGGAGCTCCTCGTCCTGACCGA
GATGTCCGCGATCTACCTGCCGCACCTGCTCCCGGACCTGTACGAGGAGATCGCCCGGCTCTCGCGCGCGTGCGGGGACC
CGGAGCGGGTCGTGCGCCCCAGCAGCTTCGGGACGGACGTGCTCGCCGTCGCCGCGGCGGCGACCGTGCTCGACTCGGTG
CACCGCAGCCCGCGCACGGTGCACACCCGCCGTGACCGGCAGGCCGCCAGGGCGGCCGAGTGGTCACGACCCCCGGTAGC
GGCTCCGTAA

Upstream 100 bases:

>100_bases
CATCCGCGTACTCCCGCCGCCGGTGCGGGAGGCGCCCCACCGTGCAGGCCTTTGACGGTCGTCGACCCGGTGGGTCGACA
CGCGCGTGAGGAGGATTTCC

Downstream 100 bases:

>100_bases
TATTTCCATCCGATCGGAAATCATTGACCTGGCGAATTAACCGAGCAACGATGGAATTGTGAAGGACGCCGCCGGGCAGC
GCCCCGTGGGAACTCGGGGG

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MPIRSANPPTISPTGLAGPGNDRRDTSKGAGSAAAVLRAVLDHGPVARGFIGTATGLSPAAVSRQTADLISLGLLRELPV
AAGAPRAGRPSVPLDVDTDTHLACGVHIAVPMLTFGIVDLRGRVVAREELPHRGEADDTLSTIVRHLPGFLRRHAGHRRV
LGLGVVTGGHVDARTGVVVEHEPLGWRDLPLGPLLAARTGLPVSVDGHARALAQAEILFGEPRARASLVHLFVGHVVDAA
IATDGVVHHGLRSAAGGVAHLNLPGADLPCSCGGRGCAQTALSDRALLVKAVELGAIPRPEAELLLGAARAGDDLVVGLL
RQRLRGVARIAATLLDMLDPELLVLTEMSAIYLPHLLPDLYEEIARLSRACGDPERVVRPSSFGTDVLAVAAAATVLDSV
HRSPRTVHTRRDRQAARAAEWSRPPVAAP

Sequences:

>Translated_429_residues
MPIRSANPPTISPTGLAGPGNDRRDTSKGAGSAAAVLRAVLDHGPVARGFIGTATGLSPAAVSRQTADLISLGLLRELPV
AAGAPRAGRPSVPLDVDTDTHLACGVHIAVPMLTFGIVDLRGRVVAREELPHRGEADDTLSTIVRHLPGFLRRHAGHRRV
LGLGVVTGGHVDARTGVVVEHEPLGWRDLPLGPLLAARTGLPVSVDGHARALAQAEILFGEPRARASLVHLFVGHVVDAA
IATDGVVHHGLRSAAGGVAHLNLPGADLPCSCGGRGCAQTALSDRALLVKAVELGAIPRPEAELLLGAARAGDDLVVGLL
RQRLRGVARIAATLLDMLDPELLVLTEMSAIYLPHLLPDLYEEIARLSRACGDPERVVRPSSFGTDVLAVAAAATVLDSV
HRSPRTVHTRRDRQAARAAEWSRPPVAAP
>Mature_428_residues
PIRSANPPTISPTGLAGPGNDRRDTSKGAGSAAAVLRAVLDHGPVARGFIGTATGLSPAAVSRQTADLISLGLLRELPVA
AGAPRAGRPSVPLDVDTDTHLACGVHIAVPMLTFGIVDLRGRVVAREELPHRGEADDTLSTIVRHLPGFLRRHAGHRRVL
GLGVVTGGHVDARTGVVVEHEPLGWRDLPLGPLLAARTGLPVSVDGHARALAQAEILFGEPRARASLVHLFVGHVVDAAI
ATDGVVHHGLRSAAGGVAHLNLPGADLPCSCGGRGCAQTALSDRALLVKAVELGAIPRPEAELLLGAARAGDDLVVGLLR
QRLRGVARIAATLLDMLDPELLVLTEMSAIYLPHLLPDLYEEIARLSRACGDPERVVRPSSFGTDVLAVAAAATVLDSVH
RSPRTVHTRRDRQAARAAEWSRPPVAAP

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI298566325, Length=297, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI298566315, Length=297, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI190014632, Length=224, Percent_Identity=29.4642857142857, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4885285, Length=224, Percent_Identity=29.4642857142857, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787878, Length=332, Percent_Identity=26.8072289156627, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786891, Length=361, Percent_Identity=26.0387811634349, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44741; Mature: 44610

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRSANPPTISPTGLAGPGNDRRDTSKGAGSAAAVLRAVLDHGPVARGFIGTATGLSPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
AVSRQTADLISLGLLRELPVAAGAPRAGRPSVPLDVDTDTHLACGVHIAVPMLTFGIVDL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHH
RGRVVAREELPHRGEADDTLSTIVRHLPGFLRRHAGHRRVLGLGVVTGGHVDARTGVVVE
CCCEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCEEEE
HEPLGWRDLPLGPLLAARTGLPVSVDGHARALAQAEILFGEPRARASLVHLFVGHVVDAA
CCCCCCCCCCCCHHHHHCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IATDGVVHHGLRSAAGGVAHLNLPGADLPCSCGGRGCAQTALSDRALLVKAVELGAIPRP
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCC
EAELLLGAARAGDDLVVGLLRQRLRGVARIAATLLDMLDPELLVLTEMSAIYLPHLLPDL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
YEEIARLSRACGDPERVVRPSSFGTDVLAVAAAATVLDSVHRSPRTVHTRRDRQAARAAE
HHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WSRPPVAAP
CCCCCCCCC
>Mature Secondary Structure 
PIRSANPPTISPTGLAGPGNDRRDTSKGAGSAAAVLRAVLDHGPVARGFIGTATGLSPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
AVSRQTADLISLGLLRELPVAAGAPRAGRPSVPLDVDTDTHLACGVHIAVPMLTFGIVDL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHH
RGRVVAREELPHRGEADDTLSTIVRHLPGFLRRHAGHRRVLGLGVVTGGHVDARTGVVVE
CCCEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCEEEE
HEPLGWRDLPLGPLLAARTGLPVSVDGHARALAQAEILFGEPRARASLVHLFVGHVVDAA
CCCCCCCCCCCCHHHHHCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IATDGVVHHGLRSAAGGVAHLNLPGADLPCSCGGRGCAQTALSDRALLVKAVELGAIPRP
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCC
EAELLLGAARAGDDLVVGLLRQRLRGVARIAATLLDMLDPELLVLTEMSAIYLPHLLPDL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
YEEIARLSRACGDPERVVRPSSFGTDVLAVAAAATVLDSVHRSPRTVHTRRDRQAARAAE
HHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WSRPPVAAP
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]