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The map label for this gene is tauD [C]

Identifier: 158312576

GI number: 158312576

Start: 837098

End: 838027

Strand: Direct

Name: tauD [C]

Synonym: Franean1_0720

Alternate gene names: 158312576

Gene position: 837098-838027 (Clockwise)

Preceding gene: 158312574

Following gene: 158312577

Centisome position: 9.32

GC content: 69.57

Gene sequence:

>930_bases
GTGACGATGACCAGCCAGGTCCAGACACTGATCGACGTCCGGCCGTTGTCCGGATACACCGGCGCCGAGATCCACGGCGT
CGACCTGCGGGAGGAACTCGACGACGCGACCATCGCCGAGATCCGGTCCGCGCTGCTGACCTGGAAGGTGGTGTTCTTCC
GCGACCAGAACCTGGACCACGCCCAGCAGGTGGCGTTCGGGCGGCGCTTCGGCAAGCTCACCCCCGCCCACCCGCACGAG
ACCGCGCCCCCGGAGGGGTTCCCCGAGATCCTGCCGATCGACAGCCGGCGCTACTCCGAAATCATCGGCAAGCGGAAGGT
CACCTACGACAACGGGTGGCACACCGACGTGACGGCGCTGGTCAACCCGCCGGCCGGGTCGATTCTGCGCGCCGACATCG
TCCCGCCCTACGGCGGCGACACCGCCTGGACGAACCTGGTCGCCGCCTACCAGGCCCTGCCCGAGCCGCTGCGGACGCTG
GCCGACAGCCTGCGCGCGCGGCACAGCTTCAACCTGCAGATCTTCGACGGCGGCGAGTACGGGAAGCGGATCGCCTCGAA
CCCGCTGGTCGCCATCCACCCGGTGGTCCGGGTGCACCCGGAGACCGGCGAGCGGGCCCTGTTCGTCAGCCCCAGCTTCA
CCGCGCGTGACAACGAGATCATCGGCCTGTCCGCCCGGCAGAGCCACCGTGTCCTCGAGTTGTTCTACGAGCAGATCGCC
CGGCCGGAGTTCACGGTGCGGTTCAAGTGGAACCCGGGTGACATCGCCTTCTGGGACAACCGCGCCACCGCGCATCTCGG
GCCGTCCGACCTCGGTCATCTCGACTTCGACCGGGTTCTCTACCGGGTGACCCTCGAGGGCGACGTCCCGGTCGGTGCCG
ACGGGGCGGAGTCGGAGCTGGTCGCCGGCCAGCCGTTCCTCGGCTCCTGA

Upstream 100 bases:

>100_bases
TTCGGGATGATTCTCGAAACCGGAGTCGGCATGTTCTCGACCGTGTTTTCAGGCGGTCCTTCTCCGGGTACCCGTACGCA
TTCGCGATCCGAAGGGAAAT

Downstream 100 bases:

>100_bases
CCGTCGCCCGCGGCGTCCTGAACCCCTGACCGCCGGCGCCGACCCAGTCGGCGCCGGCGGCTCCTGCCACCTGGAGAGAC
CCATGCACCATCGACGGACC

Product: taurine dioxygenase

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTMTSQVQTLIDVRPLSGYTGAEIHGVDLREELDDATIAEIRSALLTWKVVFFRDQNLDHAQQVAFGRRFGKLTPAHPHE
TAPPEGFPEILPIDSRRYSEIIGKRKVTYDNGWHTDVTALVNPPAGSILRADIVPPYGGDTAWTNLVAAYQALPEPLRTL
ADSLRARHSFNLQIFDGGEYGKRIASNPLVAIHPVVRVHPETGERALFVSPSFTARDNEIIGLSARQSHRVLELFYEQIA
RPEFTVRFKWNPGDIAFWDNRATAHLGPSDLGHLDFDRVLYRVTLEGDVPVGADGAESELVAGQPFLGS

Sequences:

>Translated_309_residues
MTMTSQVQTLIDVRPLSGYTGAEIHGVDLREELDDATIAEIRSALLTWKVVFFRDQNLDHAQQVAFGRRFGKLTPAHPHE
TAPPEGFPEILPIDSRRYSEIIGKRKVTYDNGWHTDVTALVNPPAGSILRADIVPPYGGDTAWTNLVAAYQALPEPLRTL
ADSLRARHSFNLQIFDGGEYGKRIASNPLVAIHPVVRVHPETGERALFVSPSFTARDNEIIGLSARQSHRVLELFYEQIA
RPEFTVRFKWNPGDIAFWDNRATAHLGPSDLGHLDFDRVLYRVTLEGDVPVGADGAESELVAGQPFLGS
>Mature_308_residues
TMTSQVQTLIDVRPLSGYTGAEIHGVDLREELDDATIAEIRSALLTWKVVFFRDQNLDHAQQVAFGRRFGKLTPAHPHET
APPEGFPEILPIDSRRYSEIIGKRKVTYDNGWHTDVTALVNPPAGSILRADIVPPYGGDTAWTNLVAAYQALPEPLRTLA
DSLRARHSFNLQIFDGGEYGKRIASNPLVAIHPVVRVHPETGERALFVSPSFTARDNEIIGLSARQSHRVLELFYEQIAR
PEFTVRFKWNPGDIAFWDNRATAHLGPSDLGHLDFDRVLYRVTLEGDVPVGADGAESELVAGQPFLGS

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=292, Percent_Identity=40.0684931506849, Blast_Score=196, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6322971, Length=290, Percent_Identity=29.6551724137931, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 34296; Mature: 34165

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTSQVQTLIDVRPLSGYTGAEIHGVDLREELDDATIAEIRSALLTWKVVFFRDQNLDH
CCCHHHHHHHHEEECCCCCCCCEEECCCHHHHHCCHHHHHHHHHHHHEEEEEEECCCCCH
AQQVAFGRRFGKLTPAHPHETAPPEGFPEILPIDSRRYSEIIGKRKVTYDNGWHTDVTAL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCEEEEE
VNPPAGSILRADIVPPYGGDTAWTNLVAAYQALPEPLRTLADSLRARHSFNLQIFDGGEY
ECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCEEEEEECCHH
GKRIASNPLVAIHPVVRVHPETGERALFVSPSFTARDNEIIGLSARQSHRVLELFYEQIA
HHHHHCCCEEEEECEEEECCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHC
RPEFTVRFKWNPGDIAFWDNRATAHLGPSDLGHLDFDRVLYRVTLEGDVPVGADGAESEL
CCCEEEEEEECCCCEEEECCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCE
VAGQPFLGS
EECCCCCCC
>Mature Secondary Structure 
TMTSQVQTLIDVRPLSGYTGAEIHGVDLREELDDATIAEIRSALLTWKVVFFRDQNLDH
CCHHHHHHHHEEECCCCCCCCEEECCCHHHHHCCHHHHHHHHHHHHEEEEEEECCCCCH
AQQVAFGRRFGKLTPAHPHETAPPEGFPEILPIDSRRYSEIIGKRKVTYDNGWHTDVTAL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCEEEEE
VNPPAGSILRADIVPPYGGDTAWTNLVAAYQALPEPLRTLADSLRARHSFNLQIFDGGEY
ECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCEEEEEECCHH
GKRIASNPLVAIHPVVRVHPETGERALFVSPSFTARDNEIIGLSARQSHRVLELFYEQIA
HHHHHCCCEEEEECEEEECCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHC
RPEFTVRFKWNPGDIAFWDNRATAHLGPSDLGHLDFDRVLYRVTLEGDVPVGADGAESEL
CCCEEEEEEECCCCEEEECCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCE
VAGQPFLGS
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]