Click here to switch to the map view.

The map label for this gene is yiaY [H]

Identifier: 157963971

GI number: 157963971

Start: 5051557

End: 5052708

Strand: Direct

Name: yiaY [H]

Synonym: Spea_4160

Alternate gene names: 157963971

Gene position: 5051557-5052708 (Clockwise)

Preceding gene: 157963970

Following gene: 157963972

Centisome position: 97.62

GC content: 43.75

Gene sequence:

>1152_bases
ATGAGCAGCGTATTTTACATGCCTCCAATGACTCTTATGGGTCAAAACGCAATCCAATCTCTAGGTTCAGAGCTAACAAG
CAAAGAGCTAAAGAAAGCACTTATCGTTACCGACGGTGTACTCGTTGAAATTGGCCTAGTTAATCGCCTAACTGATGAAC
TAAAAAGCCACAACATCGACTTTGCTATCTATGACGGCGTTAAGCCAAACCCAACTGAAAAAAATATCGAAGATGGCCTT
GCCCTACTAGCGCAAGAAAACTGTGACTTTGTTATTTCATTTGGTGGTGGTTCTTCACACGATGCAGCAAAAGGTATTGC
ATTAGTTGCTGCAAACGGTGGCCATATTCGTGATTACTCAAAAGGTGTGCATACATCTAAGAAACCACAGCTTCCACTAG
TGACCATTAACACAACTGCTGGTACGGCTTCAGAAATGACAGTATTTGCCATCATTACTAACGAAGCTGACGAAACCAAA
TACCCAGTTGTTGATAAGCATTTCACTCCAATTATTGCTGTAAATGACTCAGAACTCATGGTTGCTATGCCTAAGTTCTT
AACTGCAGCAACAGGTATGGACGCACTAACTCACGCTGTTGAAGCCTATGTTTCTACTGCAGCAACACCTATTACTGATG
CCTCAGCTATCAAGGCAATAGAGCTAATTTCACAAAACTTAGCTACTGCAGTTGAGAACGGTGAAGATCGCCAAGCACGT
GATGCAATGCAGTACGGTGAGTACCTTGCTGGTATGGCATTCTCTAATGCTTCGCTCGGTTATGTTCACTCTATGGCGCA
TCAGTTAGGCGGTGTTTACGACTTAGTACATGGTCTATGTAACGCAATTCTTCTACCTGAAGTTTCACGTTTCAACGCTG
TAGCAACCCCAACACGCTTTGTTGATATAGCCAGAGCTATGGGTGTTGATGTATCAAACATGACCCAAAAGCAAGCTATC
GAAGCCGGCATAGAGGCAATTGAAGCCCTATCTCGTCAAGTAGGCACAGCACAACGCCTAAGTGACTTAGGTGTTACTGA
AGAGAAACTCGCATTCATGGCGCAAAACGCGCTAAACGATGCCTGCTCTCTAACTAATCCACGTAAAGCGAGCCTTGAAG
AAATCATCACTATCTTCAGAGCGCGTTTGTAA

Upstream 100 bases:

>100_bases
ACTGATGCCTTCAAACGATAAAAATCACTTTTATATTATCAACCTCTTTAATTTTTTTATTTAACAATTTGATTTTTAAC
TTAAATTTTAGGAAAACATT

Downstream 100 bases:

>100_bases
TTCAGTCTTAAATCCATCAAATAAGGGGGGGATAAGCTTCCCCCTCATTCATTATTCTAGGATCCCCATGACAAGCTTAA
CCAGTCAAAGCAACAAAATT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSSVFYMPPMTLMGQNAIQSLGSELTSKELKKALIVTDGVLVEIGLVNRLTDELKSHNIDFAIYDGVKPNPTEKNIEDGL
ALLAQENCDFVISFGGGSSHDAAKGIALVAANGGHIRDYSKGVHTSKKPQLPLVTINTTAGTASEMTVFAIITNEADETK
YPVVDKHFTPIIAVNDSELMVAMPKFLTAATGMDALTHAVEAYVSTAATPITDASAIKAIELISQNLATAVENGEDRQAR
DAMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPEVSRFNAVATPTRFVDIARAMGVDVSNMTQKQAI
EAGIEAIEALSRQVGTAQRLSDLGVTEEKLAFMAQNALNDACSLTNPRKASLEEIITIFRARL

Sequences:

>Translated_383_residues
MSSVFYMPPMTLMGQNAIQSLGSELTSKELKKALIVTDGVLVEIGLVNRLTDELKSHNIDFAIYDGVKPNPTEKNIEDGL
ALLAQENCDFVISFGGGSSHDAAKGIALVAANGGHIRDYSKGVHTSKKPQLPLVTINTTAGTASEMTVFAIITNEADETK
YPVVDKHFTPIIAVNDSELMVAMPKFLTAATGMDALTHAVEAYVSTAATPITDASAIKAIELISQNLATAVENGEDRQAR
DAMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPEVSRFNAVATPTRFVDIARAMGVDVSNMTQKQAI
EAGIEAIEALSRQVGTAQRLSDLGVTEEKLAFMAQNALNDACSLTNPRKASLEEIITIFRARL
>Mature_382_residues
SSVFYMPPMTLMGQNAIQSLGSELTSKELKKALIVTDGVLVEIGLVNRLTDELKSHNIDFAIYDGVKPNPTEKNIEDGLA
LLAQENCDFVISFGGGSSHDAAKGIALVAANGGHIRDYSKGVHTSKKPQLPLVTINTTAGTASEMTVFAIITNEADETKY
PVVDKHFTPIIAVNDSELMVAMPKFLTAATGMDALTHAVEAYVSTAATPITDASAIKAIELISQNLATAVENGEDRQARD
AMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPEVSRFNAVATPTRFVDIARAMGVDVSNMTQKQAIE
AGIEAIEALSRQVGTAQRLSDLGVTEEKLAFMAQNALNDACSLTNPRKASLEEIITIFRARL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=335, Percent_Identity=27.1641791044776, Blast_Score=109, Evalue=4e-24,
Organism=Escherichia coli, GI48994951, Length=382, Percent_Identity=55.2356020942408, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1789163, Length=370, Percent_Identity=43.5135135135135, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI87082107, Length=378, Percent_Identity=38.3597883597884, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1787493, Length=388, Percent_Identity=31.9587628865979, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI1789386, Length=347, Percent_Identity=23.342939481268, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17537053, Length=413, Percent_Identity=23.9709443099274, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321181, Length=384, Percent_Identity=48.4375, Blast_Score=365, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24657991, Length=419, Percent_Identity=24.3436754176611, Blast_Score=111, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40907; Mature: 40776

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVFYMPPMTLMGQNAIQSLGSELTSKELKKALIVTDGVLVEIGLVNRLTDELKSHNID
CCCEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHEECCEEEEHHHHHHHHHHHHHCCCC
FAIYDGVKPNPTEKNIEDGLALLAQENCDFVISFGGGSSHDAAKGIALVAANGGHIRDYS
EEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCHHH
KGVHTSKKPQLPLVTINTTAGTASEMTVFAIITNEADETKYPVVDKHFTPIIAVNDSELM
CCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCE
VAMPKFLTAATGMDALTHAVEAYVSTAATPITDASAIKAIELISQNLATAVENGEDRQAR
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
DAMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPEVSRFNAVATPTRF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHCCCCCCCHHH
VDIARAMGVDVSNMTQKQAIEAGIEAIEALSRQVGTAQRLSDLGVTEEKLAFMAQNALND
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHH
ACSLTNPRKASLEEIITIFRARL
HHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSVFYMPPMTLMGQNAIQSLGSELTSKELKKALIVTDGVLVEIGLVNRLTDELKSHNID
CCEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHEECCEEEEHHHHHHHHHHHHHCCCC
FAIYDGVKPNPTEKNIEDGLALLAQENCDFVISFGGGSSHDAAKGIALVAANGGHIRDYS
EEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCHHH
KGVHTSKKPQLPLVTINTTAGTASEMTVFAIITNEADETKYPVVDKHFTPIIAVNDSELM
CCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCE
VAMPKFLTAATGMDALTHAVEAYVSTAATPITDASAIKAIELISQNLATAVENGEDRQAR
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
DAMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPEVSRFNAVATPTRF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHCCCCCCCHHH
VDIARAMGVDVSNMTQKQAIEAGIEAIEALSRQVGTAQRLSDLGVTEEKLAFMAQNALND
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHH
ACSLTNPRKASLEEIITIFRARL
HHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]