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The map label for this gene is ubiC [H]

Identifier: 157963959

GI number: 157963959

Start: 5037533

End: 5038090

Strand: Direct

Name: ubiC [H]

Synonym: Spea_4148

Alternate gene names: 157963959

Gene position: 5037533-5038090 (Clockwise)

Preceding gene: 157963955

Following gene: 157963964

Centisome position: 97.35

GC content: 47.31

Gene sequence:

>558_bases
ATGACTAGGTTAAGCTTCCCTTATGGTGAATCAATCGAATGGTTTTCGCCAGAACAAATCTCCAATTTACCTGCGCCACC
TCTTAAGGACTGGCTGCTCAGCACATGTAGCTTAACCCAAAAGCTAAAGAAGCAATGCGCTCACTTTGAAGTAAAAATTC
TTGGAGAAGATACCCTCTCTTTGCAACCTGAAGACTCATTTGGCAGTGAAACTATCTGGGTTAGAGAGGTCTTACTCATT
CTAGATGGCACCCCATGGATCTTCGCCAGAACCTTGATCCCTGGGCGTCTGCTAGAAAAGAAGCAGCAGGAGTTTTTAGG
TTTAGGCGTTAGGCCCTTGGGCGAACTACTCTATTCGACCGATGCGTTTATTCCCGGGCGAATCGAAGTGGCCCATTTTG
AAGCCTGTTGTAAGATAGCTAAACTTGCCGAATCGCTGCAACAAGACGTGACCCAACCGCTATGGGGACGTCGTCGCTAT
TTCCAGTATGACAACGAGCAATTAATCGTCAGCGAAGTATTTCTGCCCGCCGCTCAGCAAGCCATTGCCAAGCTATAA

Upstream 100 bases:

>100_bases
ATTGTCACGTCAGCATTCTAAGTAGACAATCTCTACCTGCGTCGACAGCGGCGTGCTAGACTGCTTCGGTTTGCTGTATT
GTACCGAGAATTAGACGACT

Downstream 100 bases:

>100_bases
ACATTGGCTGTTATGTAACAGCTAAAAAAAGCCCGTGAATTGGGCTTTTTGTATTTATGATTGTTGGCGTCGGTGCGCAC
TCAACAAGCCAAGCACCAAT

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTRLSFPYGESIEWFSPEQISNLPAPPLKDWLLSTCSLTQKLKKQCAHFEVKILGEDTLSLQPEDSFGSETIWVREVLLI
LDGTPWIFARTLIPGRLLEKKQQEFLGLGVRPLGELLYSTDAFIPGRIEVAHFEACCKIAKLAESLQQDVTQPLWGRRRY
FQYDNEQLIVSEVFLPAAQQAIAKL

Sequences:

>Translated_185_residues
MTRLSFPYGESIEWFSPEQISNLPAPPLKDWLLSTCSLTQKLKKQCAHFEVKILGEDTLSLQPEDSFGSETIWVREVLLI
LDGTPWIFARTLIPGRLLEKKQQEFLGLGVRPLGELLYSTDAFIPGRIEVAHFEACCKIAKLAESLQQDVTQPLWGRRRY
FQYDNEQLIVSEVFLPAAQQAIAKL
>Mature_184_residues
TRLSFPYGESIEWFSPEQISNLPAPPLKDWLLSTCSLTQKLKKQCAHFEVKILGEDTLSLQPEDSFGSETIWVREVLLIL
DGTPWIFARTLIPGRLLEKKQQEFLGLGVRPLGELLYSTDAFIPGRIEVAHFEACCKIAKLAESLQQDVTQPLWGRRRYF
QYDNEQLIVSEVFLPAAQQAIAKL

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway [H]

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family [H]

Homologues:

Organism=Escherichia coli, GI87082361, Length=162, Percent_Identity=29.0123456790123, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007440 [H]

Pfam domain/function: PF04345 Chor_lyase [H]

EC number: =4.1.3.40 [H]

Molecular weight: Translated: 21095; Mature: 20963

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLSFPYGESIEWFSPEQISNLPAPPLKDWLLSTCSLTQKLKKQCAHFEVKILGEDTLS
CCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCC
LQPEDSFGSETIWVREVLLILDGTPWIFARTLIPGRLLEKKQQEFLGLGVRPLGELLYST
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHC
DAFIPGRIEVAHFEACCKIAKLAESLQQDVTQPLWGRRRYFQYDNEQLIVSEVFLPAAQQ
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
AIAKL
HHHCC
>Mature Secondary Structure 
TRLSFPYGESIEWFSPEQISNLPAPPLKDWLLSTCSLTQKLKKQCAHFEVKILGEDTLS
CCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCC
LQPEDSFGSETIWVREVLLILDGTPWIFARTLIPGRLLEKKQQEFLGLGVRPLGELLYST
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHC
DAFIPGRIEVAHFEACCKIAKLAESLQQDVTQPLWGRRRYFQYDNEQLIVSEVFLPAAQQ
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
AIAKL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]