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The map label for this gene is atoS [H]

Identifier: 157963903

GI number: 157963903

Start: 4975105

End: 4977225

Strand: Reverse

Name: atoS [H]

Synonym: Spea_4092

Alternate gene names: 157963903

Gene position: 4977225-4975105 (Counterclockwise)

Preceding gene: 157963904

Following gene: 157963899

Centisome position: 96.19

GC content: 48.75

Gene sequence:

>2121_bases
ATGTTTGGTGTTAGTTGGCAACAAATGCAGGCTAAGGTGCGCTATCGCATCCTGATTTTAACCCTGTTGCCCATCTTGCT
CACTCTTGTGAGTTTGGTTTTTATTACCATCTATTGGAATATTAGCTACACAGGTAAACAGCTGTTTATGAAGGTCAAAG
CCGATTTGACCGTTGCAAACAGCACCCTAGTGACCGTGCAAACAAACCAAGAGAACCAGCTAGAGTTGGTGATGGAGTCT
TGGCAGTTCCAGAATGATTTCAGGAAAATTGGCAACGGCGCCCAGCTCCCTCGCGACAACTTGCAGCTGGTACTAGAACA
AGCGAAGAAAGATCTTAATTTAGATTTCTTACGCCTAGTCAGTGTTGCGGAGGCCGCGGCGGATCCTGATCTGCGGCAGA
TGTTGCCGCATATCGAAGGTTTAGCCCCTTTCTCTGGCTTGATGGTGCTTGAACCGAGTCGATTGGCTCGCATCGACCCT
GTACTCGCCGATAGGGCCAAAGTGTCTGTAATGAAGACCTTGCGAGCTCAAGAGCCCAGTAAACATGAAGAGAAGCGTGG
CCTGTTAAGTCGCAGCTTGCTGCCTGTTGCCGACATGAATGGTAATGTCGCCTGGTACTTAGATGGCGGCATCATGCTTA
ATCGCGATACCCGCATTGTCGACCATATTCGTGATCTGGTGTACGACAAGGGCACGCTGCCGGAGCGCTCAATCGGTACC
GTGACTATTTTCCTCGATAATATCCGTATCAGTACCAATGTGCCGTTGCACTTCTTTCCTCAAGGAGGTGATCAGCAAGG
GCGTGCCTTAGGCAGCTTAGTCTCATCTGAGGTACGCGAAAAGGTATTGATTCAAGGGCTACTATGGGTCGATAGAGCTT
TCGTCTTTAATGACTGGTTTATCTCGGCATACTCACCGCTGGAAGATATTAACGGTAAGCGGATCGGTATGATCTATACC
GGATTTTCTGAGTCTCCATTTATCCATAACTACCTGCTCAATATTATCGAACTGGGCACCATCTTGATGCTGGTGTTGCT
GGTCTCTGGCTGGTTGGTATACCGCGGTGCCTATAGCTTGTTACAACCTATTGAACGCATCCACCACGTGGTGAAAGCGG
TGCAGTCTGGACGTAATCTACGTATAGGTTCACTGGGTTTAGACAGCGATAATGAGCTATCTAATCTGGCCGAGCAGTTT
GACCGCATGTTGGATCTACTGCAGATGCGTAACAGCCAGATCCAAGCTGCCGCTGAGCAGCTTGAAGTCAAAGTCGAAGA
ACGAACTCGCAGCCTACAAGAGAAGACAGAAGAGCTGCAGGCTAACGTCGCTCTACTCAATGAAACCCGACAGCAGCTGG
TGATCAACGAGAAGTTGACTGCCCTAGGTGAGCTAACTGCGGGTATTGCCCATGAGATCAATAACCCTACGGCGGTGATT
CTGGGTAATATGGAGCTGCTTAAGTATGAGCTTGGAGATAGAGCGGCCGATGTCGAAGAAGAGATCGAGCTGGTTATTCA
GCAAGTAGGCCGTATTAGCACCATTATTCGCAGTCTGTTGCAATACAGCCGCCCTGGTGAGTTTAATGCACCGCTTGAGA
TGCACCAGATCACGCCGATTATCGAAGAGATGTTGGTATTGGTGCGTCACTCTATCCAGAAACAGCAGGTGGTACTCAAT
CAAGAGCTTAACGCTAGCTACCCGATTCAGGTTAATCGCCCGCAGCTACTACAGGTACTGATTAACCTCGTCGTTAATGC
GGCTCACGCAATGAATGGTAAGGGGCAGATCTGGATAAGAACCTATGATTGGGTACAACGTGGAGAGCCTGTTGGCGTCA
AGATTGAAGTTGAAGACGAAGGTAAAGGGATCCCAGAAGAGGAGCTCAATCGCATTTTCGATCCGTTTTTCACTACCCGT
AAAGACGGCACTGGACTGGGGCTATCGCTGAGTTACGGTATCATTAAGCGTATTGGTGGCACCATAGAAGTCAACTCTAC
CGTAGGCAAGGGCAGTCTATTCACCATAGGCTTATACCACAAGGCCATTGAAGACCAGAGTAATACCCCCTATGAAGGTT
TGCAATTTTGCGGAAAACATTCAGACATGTCGCGAGACTAG

Upstream 100 bases:

>100_bases
CGAAAATATAAAGAATGGTTCGGCGGTGAAGCCGACAAAGAAGAATCTTAAACAATATTGAGATTGCTCTAGGGGAGTGT
AGGTGTCTTTTTTTTCCAAT

Downstream 100 bases:

>100_bases
TTAGAGAGCCGGAAAGTACCTCGGCTACTCTCTCATTTCAATTCATATAAGTTGACCTAATCTCAAATCACAGGCAAAAA
AATAGCCGAGATAATATCTC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLTVANSTLVTVQTNQENQLELVMES
WQFQNDFRKIGNGAQLPRDNLQLVLEQAKKDLNLDFLRLVSVAEAAADPDLRQMLPHIEGLAPFSGLMVLEPSRLARIDP
VLADRAKVSVMKTLRAQEPSKHEEKRGLLSRSLLPVADMNGNVAWYLDGGIMLNRDTRIVDHIRDLVYDKGTLPERSIGT
VTIFLDNIRISTNVPLHFFPQGGDQQGRALGSLVSSEVREKVLIQGLLWVDRAFVFNDWFISAYSPLEDINGKRIGMIYT
GFSESPFIHNYLLNIIELGTILMLVLLVSGWLVYRGAYSLLQPIERIHHVVKAVQSGRNLRIGSLGLDSDNELSNLAEQF
DRMLDLLQMRNSQIQAAAEQLEVKVEERTRSLQEKTEELQANVALLNETRQQLVINEKLTALGELTAGIAHEINNPTAVI
LGNMELLKYELGDRAADVEEEIELVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPIIEEMLVLVRHSIQKQQVVLN
QELNASYPIQVNRPQLLQVLINLVVNAAHAMNGKGQIWIRTYDWVQRGEPVGVKIEVEDEGKGIPEEELNRIFDPFFTTR
KDGTGLGLSLSYGIIKRIGGTIEVNSTVGKGSLFTIGLYHKAIEDQSNTPYEGLQFCGKHSDMSRD

Sequences:

>Translated_706_residues
MFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLTVANSTLVTVQTNQENQLELVMES
WQFQNDFRKIGNGAQLPRDNLQLVLEQAKKDLNLDFLRLVSVAEAAADPDLRQMLPHIEGLAPFSGLMVLEPSRLARIDP
VLADRAKVSVMKTLRAQEPSKHEEKRGLLSRSLLPVADMNGNVAWYLDGGIMLNRDTRIVDHIRDLVYDKGTLPERSIGT
VTIFLDNIRISTNVPLHFFPQGGDQQGRALGSLVSSEVREKVLIQGLLWVDRAFVFNDWFISAYSPLEDINGKRIGMIYT
GFSESPFIHNYLLNIIELGTILMLVLLVSGWLVYRGAYSLLQPIERIHHVVKAVQSGRNLRIGSLGLDSDNELSNLAEQF
DRMLDLLQMRNSQIQAAAEQLEVKVEERTRSLQEKTEELQANVALLNETRQQLVINEKLTALGELTAGIAHEINNPTAVI
LGNMELLKYELGDRAADVEEEIELVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPIIEEMLVLVRHSIQKQQVVLN
QELNASYPIQVNRPQLLQVLINLVVNAAHAMNGKGQIWIRTYDWVQRGEPVGVKIEVEDEGKGIPEEELNRIFDPFFTTR
KDGTGLGLSLSYGIIKRIGGTIEVNSTVGKGSLFTIGLYHKAIEDQSNTPYEGLQFCGKHSDMSRD
>Mature_706_residues
MFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLTVANSTLVTVQTNQENQLELVMES
WQFQNDFRKIGNGAQLPRDNLQLVLEQAKKDLNLDFLRLVSVAEAAADPDLRQMLPHIEGLAPFSGLMVLEPSRLARIDP
VLADRAKVSVMKTLRAQEPSKHEEKRGLLSRSLLPVADMNGNVAWYLDGGIMLNRDTRIVDHIRDLVYDKGTLPERSIGT
VTIFLDNIRISTNVPLHFFPQGGDQQGRALGSLVSSEVREKVLIQGLLWVDRAFVFNDWFISAYSPLEDINGKRIGMIYT
GFSESPFIHNYLLNIIELGTILMLVLLVSGWLVYRGAYSLLQPIERIHHVVKAVQSGRNLRIGSLGLDSDNELSNLAEQF
DRMLDLLQMRNSQIQAAAEQLEVKVEERTRSLQEKTEELQANVALLNETRQQLVINEKLTALGELTAGIAHEINNPTAVI
LGNMELLKYELGDRAADVEEEIELVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPIIEEMLVLVRHSIQKQQVVLN
QELNASYPIQVNRPQLLQVLINLVVNAAHAMNGKGQIWIRTYDWVQRGEPVGVKIEVEDEGKGIPEEELNRIFDPFFTTR
KDGTGLGLSLSYGIIKRIGGTIEVNSTVGKGSLFTIGLYHKAIEDQSNTPYEGLQFCGKHSDMSRD

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=36.9565217391304, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=36.7256637168142, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1790300, Length=216, Percent_Identity=32.8703703703704, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1789149, Length=457, Percent_Identity=23.8512035010941, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI87081816, Length=286, Percent_Identity=27.972027972028, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=28.1512605042017, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=27.8761061946903, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87082128, Length=219, Percent_Identity=29.2237442922374, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=28.4444444444444, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=26.4069264069264, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1789808, Length=214, Percent_Identity=28.0373831775701, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79573; Mature: 79573

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLTVAN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHEEHCCCEEEEC
STLVTVQTNQENQLELVMESWQFQNDFRKIGNGAQLPRDNLQLVLEQAKKDLNLDFLRLV
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
SVAEAAADPDLRQMLPHIEGLAPFSGLMVLEPSRLARIDPVLADRAKVSVMKTLRAQEPS
HHHHHHCCCHHHHHHHHHCCCCCCCCEEEECCHHHHHCCHHHHHHHHHHHHHHHHCCCCC
KHEEKRGLLSRSLLPVADMNGNVAWYLDGGIMLNRDTRIVDHIRDLVYDKGTLPERSIGT
HHHHHHHHHHHCCCCEECCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCE
VTIFLDNIRISTNVPLHFFPQGGDQQGRALGSLVSSEVREKVLIQGLLWVDRAFVFNDWF
EEEEEECEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ISAYSPLEDINGKRIGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGWLVYRGAYSL
HCCCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQPIERIHHVVKAVQSGRNLRIGSLGLDSDNELSNLAEQFDRMLDLLQMRNSQIQAAAEQ
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LEVKVEERTRSLQEKTEELQANVALLNETRQQLVINEKLTALGELTAGIAHEINNPTAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LGNMELLKYELGDRAADVEEEIELVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPI
EECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
IEEMLVLVRHSIQKQQVVLNQELNASYPIQVNRPQLLQVLINLVVNAAHAMNGKGQIWIR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEE
TYDWVQRGEPVGVKIEVEDEGKGIPEEELNRIFDPFFTTRKDGTGLGLSLSYGIIKRIGG
EEHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHCCC
TIEVNSTVGKGSLFTIGLYHKAIEDQSNTPYEGLQFCGKHSDMSRD
CEEECCCCCCCCEEEEEHHHHHHCCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLTVAN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHEEHCCCEEEEC
STLVTVQTNQENQLELVMESWQFQNDFRKIGNGAQLPRDNLQLVLEQAKKDLNLDFLRLV
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
SVAEAAADPDLRQMLPHIEGLAPFSGLMVLEPSRLARIDPVLADRAKVSVMKTLRAQEPS
HHHHHHCCCHHHHHHHHHCCCCCCCCEEEECCHHHHHCCHHHHHHHHHHHHHHHHCCCCC
KHEEKRGLLSRSLLPVADMNGNVAWYLDGGIMLNRDTRIVDHIRDLVYDKGTLPERSIGT
HHHHHHHHHHHCCCCEECCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCE
VTIFLDNIRISTNVPLHFFPQGGDQQGRALGSLVSSEVREKVLIQGLLWVDRAFVFNDWF
EEEEEECEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ISAYSPLEDINGKRIGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGWLVYRGAYSL
HCCCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQPIERIHHVVKAVQSGRNLRIGSLGLDSDNELSNLAEQFDRMLDLLQMRNSQIQAAAEQ
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LEVKVEERTRSLQEKTEELQANVALLNETRQQLVINEKLTALGELTAGIAHEINNPTAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LGNMELLKYELGDRAADVEEEIELVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPI
EECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
IEEMLVLVRHSIQKQQVVLNQELNASYPIQVNRPQLLQVLINLVVNAAHAMNGKGQIWIR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEE
TYDWVQRGEPVGVKIEVEDEGKGIPEEELNRIFDPFFTTRKDGTGLGLSLSYGIIKRIGG
EEHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHCCC
TIEVNSTVGKGSLFTIGLYHKAIEDQSNTPYEGLQFCGKHSDMSRD
CEEECCCCCCCCEEEEEHHHHHHCCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]