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The map label for this gene is ompR [H]

Identifier: 157963828

GI number: 157963828

Start: 4879682

End: 4880407

Strand: Direct

Name: ompR [H]

Synonym: Spea_4017

Alternate gene names: 157963828

Gene position: 4879682-4880407 (Clockwise)

Preceding gene: 157963825

Following gene: 157963829

Centisome position: 94.3

GC content: 50.28

Gene sequence:

>726_bases
ATGGGACACGAAACCTCAAAAATTCTCGTCGTCGACGATGATATGAGACTACGCGCATTACTAGAACGTTACTTGATGGA
GCAAGGTTATCAAGTGCGTAGCGCCGCCAATGCAGAACAGATGGATCGCCTACTCGAGCGAGAAAACTTCCACCTGTTAG
TACTCGATCTAATGCTTCCCGGTGAAGACGGCCTGTCTATCTGTCGCCGACTTCGTCAAACTGGCAACCCAATTCCTATC
GTGATGTTGACCGCAAAAGGCGACGAAGTAGATAGAATCATCGGCCTAGAGTTAGGTGCCGATGACTACTTGCCAAAGCC
CTTTAATCCACGAGAGCTATTAGCCCGCATTAAAGCCGTTATGCGTCGTCAAACCCCCGAGGTGCCAGGTGCTCCAACCC
AGCAAGAAGAAGAGATCACCTTTGGTGAATACTCTCTAAACCTTGCGACCCGTGAAATGCATCATGGCGAAGAGAGCATC
GCACTGACTAGCGGCGAATTTGCCGTGCTTAAAGTGCTTGTCAGCCATCCAAGAGAGCCCCTTTCACGTGACAAGCTGAT
GAATCTGGCACGTGGCCGCGATTACTCGGCACTAGAGCGATCAATTGACGTGCAAGTTTCACGTCTGCGTCGACTCATTG
AAAAAGATGCTGCCAACCCGCGCTACATTCAGACTGTGTGGGGCTTAGGTTATGTATTTGTGCCAGATGGCCAGTCACGC
AAATAA

Upstream 100 bases:

>100_bases
ATTAACATATTAAAACAGCTATATTAGAATGAATCACATTCAATATCAGCTATTTGCCTACTAATACAGAGTTGGCCGCC
GAGTTAAAAGGACCTTAAGC

Downstream 100 bases:

>100_bases
CTCGGCAACAATAATTAAGTGATAATGACTAAGTGATAATGACTAAGAGATAATGACTAAGTGACAATGACTAAGTGACA
ATAGTTAAGTGACTATAAAC

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MGHETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQTGNPIPI
VMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTPEVPGAPTQQEEEITFGEYSLNLATREMHHGEESI
ALTSGEFAVLKVLVSHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDAANPRYIQTVWGLGYVFVPDGQSR
K

Sequences:

>Translated_241_residues
MGHETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQTGNPIPI
VMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTPEVPGAPTQQEEEITFGEYSLNLATREMHHGEESI
ALTSGEFAVLKVLVSHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDAANPRYIQTVWGLGYVFVPDGQSR
K
>Mature_240_residues
GHETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQTGNPIPIV
MLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTPEVPGAPTQQEEEITFGEYSLNLATREMHHGEESIA
LTSGEFAVLKVLVSHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDAANPRYIQTVWGLGYVFVPDGQSRK

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=79.1489361702128, Blast_Score=393, Evalue=1e-111,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=38.4279475982533, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=35.8649789029536, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.7682403433476, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=38.2978723404255, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=32.4894514767932, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=36.5217391304348, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=34.3220338983051, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=32.6086956521739, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=34.9137931034483, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=36.2445414847162, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=233, Percent_Identity=31.7596566523605, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=30.3030303030303, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=32.5991189427313, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=31.7073170731707, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27462; Mature: 27331

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLP
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCEEEEEEEECC
GEDGLSICRRLRQTGNPIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAV
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHH
MRRQTPEVPGAPTQQEEEITFGEYSLNLATREMHHGEESIALTSGEFAVLKVLVSHPREP
HHHCCCCCCCCCCCCCCCEEECCEEEHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCC
LSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDAANPRYIQTVWGLGYVFVPDGQSR
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEECCCCCC
K
C
>Mature Secondary Structure 
GHETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLP
CCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCEEEEEEEECC
GEDGLSICRRLRQTGNPIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAV
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHH
MRRQTPEVPGAPTQQEEEITFGEYSLNLATREMHHGEESIALTSGEFAVLKVLVSHPREP
HHHCCCCCCCCCCCCCCCEEECCEEEHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCC
LSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDAANPRYIQTVWGLGYVFVPDGQSR
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEECCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]