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The map label for this gene is nfuA [H]

Identifier: 157963821

GI number: 157963821

Start: 4870783

End: 4871361

Strand: Reverse

Name: nfuA [H]

Synonym: Spea_4010

Alternate gene names: 157963821

Gene position: 4871361-4870783 (Counterclockwise)

Preceding gene: 157963823

Following gene: 157963819

Centisome position: 94.14

GC content: 43.87

Gene sequence:

>579_bases
ATGATTACCATTTCCGAAGCAGCTCAGGCGCATTTTGTTAAATTGTTATCAGATCAGCCTGAAGGAACTCACATTCGAGT
ATTTGTTATCAGCCCAGGTACTGCGCAGGCTGAGTGTGGCGTATCATATTGTCCACCAGACGCTGTTGAAGCTGATGACA
CAGAGATCGAATTTAATGGCTTTAATGCCATGGTTGATGAGAAAAGCGCTCCTTTCCTTGAAGAAGCGACAATTGACTTC
GTTACCGATCAGTTAGGTTCTCAGTTAACGCTTAAGGCACCTAACGCTAAAATGCGTAAAGTGTCTGATGACGCTTCATT
ATCTGAGCGTATCGAGTATGTTATCCAGTCTGAAATTAACCCACAGCTTGCTAGCCATGGTGGTAACATCATGCTAGTTG
AAATCACTGAAGACGGCATTGCAGTATTGCAGTTTGGTGGTGGTTGTAATGGTTGCTCTATGGTTGATGTAACTCTAAAA
GATGGTATCGAGAAGCAACTACTTGATATGTTCCCAGGTGAACTATCAGGCGTTAAAGACGTGACCGAGCACCAGCATGG
TGAGCACTCTTACCAGTAA

Upstream 100 bases:

>100_bases
TCTGTGAGCCTTGGGGGCTACAAAGGAATGCAGAGTAAGAGTATTATAGGGTTAATTCTTACTAAAACACTCAGGTTTAT
CCCTGACGGAGCATGTTTTC

Downstream 100 bases:

>100_bases
TACTGGATGCAGAATTTGCATAAAAAACGCGGCTCTAGCTCTAAGTCTAGGTCGCGTTTTTTGTTTCTTACTCAAGAAAG
CAAATATAAAAGCTAGTTTA

Product: putative DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MITISEAAQAHFVKLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTEIEFNGFNAMVDEKSAPFLEEATIDF
VTDQLGSQLTLKAPNAKMRKVSDDASLSERIEYVIQSEINPQLASHGGNIMLVEITEDGIAVLQFGGGCNGCSMVDVTLK
DGIEKQLLDMFPGELSGVKDVTEHQHGEHSYQ

Sequences:

>Translated_192_residues
MITISEAAQAHFVKLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTEIEFNGFNAMVDEKSAPFLEEATIDF
VTDQLGSQLTLKAPNAKMRKVSDDASLSERIEYVIQSEINPQLASHGGNIMLVEITEDGIAVLQFGGGCNGCSMVDVTLK
DGIEKQLLDMFPGELSGVKDVTEHQHGEHSYQ
>Mature_192_residues
MITISEAAQAHFVKLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTEIEFNGFNAMVDEKSAPFLEEATIDF
VTDQLGSQLTLKAPNAKMRKVSDDASLSERIEYVIQSEINPQLASHGGNIMLVEITEDGIAVLQFGGGCNGCSMVDVTLK
DGIEKQLLDMFPGELSGVKDVTEHQHGEHSYQ

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins [H]

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family [H]

Homologues:

Organism=Escherichia coli, GI1789819, Length=191, Percent_Identity=76.4397905759162, Blast_Score=307, Evalue=4e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- ProDom:   PD002830 [H]

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU [H]

EC number: NA

Molecular weight: Translated: 20759; Mature: 20759

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITISEAAQAHFVKLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTEIEFNG
CEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECC
FNAMVDEKSAPFLEEATIDFVTDQLGSQLTLKAPNAKMRKVSDDASLSERIEYVIQSEIN
CEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCCHHHHHHHHHHHCCC
PQLASHGGNIMLVEITEDGIAVLQFGGGCNGCSMVDVTLKDGIEKQLLDMFPGELSGVKD
HHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCHH
VTEHQHGEHSYQ
HHHHCCCCCCCC
>Mature Secondary Structure
MITISEAAQAHFVKLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTEIEFNG
CEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECC
FNAMVDEKSAPFLEEATIDFVTDQLGSQLTLKAPNAKMRKVSDDASLSERIEYVIQSEIN
CEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCCHHHHHHHHHHHCCC
PQLASHGGNIMLVEITEDGIAVLQFGGGCNGCSMVDVTLKDGIEKQLLDMFPGELSGVKD
HHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCHH
VTEHQHGEHSYQ
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA