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The map label for this gene is comF [H]

Identifier: 157963823

GI number: 157963823

Start: 4874147

End: 4874896

Strand: Reverse

Name: comF [H]

Synonym: Spea_4012

Alternate gene names: 157963823

Gene position: 4874896-4874147 (Counterclockwise)

Preceding gene: 157963826

Following gene: 157963821

Centisome position: 94.21

GC content: 50.53

Gene sequence:

>750_bases
TTGAAACTTAACAATGAAAAGGATTTCATTATTAGCAAAACACCTTGGACTCGGTGGTTATCGGCAATTTTACCCAATCG
CTGTTTATTGTGCCATCAACATATTGATTCGGTTAATCGTGGGATCTGTTCCGTTTGCCTGCATGCTTGCCGTTATCAAA
CGCCCATCTGTTTGGGCTGTGGCGGTGAGATGCTAATAAGCATGGCTTTCTGCGGTCATTGCATGGCATCGACGCCATTA
ACCGTTATCGCTCCCTGCAGTTATCACCATGGCCTAGGTCACTGGGTCGGACAGGTTAAGTATCAGGCGCAATTTGCGGT
GATCGATGTGCTGGTGGACGCGCTGGTTCAGCGGATCCTCTATCTAGAATATTTAGGCTTTATCCAGCTGCCACAGGCGT
TGATTGCCGTGCCGCTACATAAGAGCAGGCTGCGGCAACGGGGCTTTAATCAGGCTTGGCTAATCGCTAAGGCACTGTCT
AAGCGACTCGATATACCACTGGTCGATAATATGCTGTTTAGGATGAAAGAGACTCAGCCGCAAGCGGGATTGTCGGGTAG
GTTACGGCGTAAAAACCTTAAAGGCGCCTTTGAGCTTTCACCTGAGTTTAACTGGCAGCGGGTAGCGCTGATCGATGATG
TGGTGACCACGGGCACGACGGTAGAGGAGATCGCGAAATTATTGCAGCGAAAGCACACTCAGGTTCAAGTTTGGTGCCTG
GCTAGAGCCGAGGCACCGGGGCGCCGCTAA

Upstream 100 bases:

>100_bases
TGTTAACCCCCCAACCATGAAGCATTACAACATCGGGCCCTTGACCGATAGATTCGATATGTAGCTGGCTCTGACTCATT
TTGGGCCTCATGGGTTAACG

Downstream 100 bases:

>100_bases
ATGCTATAGCTATCGAGTGACAGTTAAGGGGCTATTAGTGCAGCGCTGGAATGAAGTAAAGCGCATTGGCATAAGCTTTC
TCAGAGCCAAGCCAAATATT

Product: competence protein ComF

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKLNNEKDFIISKTPWTRWLSAILPNRCLLCHQHIDSVNRGICSVCLHACRYQTPICLGCGGEMLISMAFCGHCMASTPL
TVIAPCSYHHGLGHWVGQVKYQAQFAVIDVLVDALVQRILYLEYLGFIQLPQALIAVPLHKSRLRQRGFNQAWLIAKALS
KRLDIPLVDNMLFRMKETQPQAGLSGRLRRKNLKGAFELSPEFNWQRVALIDDVVTTGTTVEEIAKLLQRKHTQVQVWCL
ARAEAPGRR

Sequences:

>Translated_249_residues
MKLNNEKDFIISKTPWTRWLSAILPNRCLLCHQHIDSVNRGICSVCLHACRYQTPICLGCGGEMLISMAFCGHCMASTPL
TVIAPCSYHHGLGHWVGQVKYQAQFAVIDVLVDALVQRILYLEYLGFIQLPQALIAVPLHKSRLRQRGFNQAWLIAKALS
KRLDIPLVDNMLFRMKETQPQAGLSGRLRRKNLKGAFELSPEFNWQRVALIDDVVTTGTTVEEIAKLLQRKHTQVQVWCL
ARAEAPGRR
>Mature_249_residues
MKLNNEKDFIISKTPWTRWLSAILPNRCLLCHQHIDSVNRGICSVCLHACRYQTPICLGCGGEMLISMAFCGHCMASTPL
TVIAPCSYHHGLGHWVGQVKYQAQFAVIDVLVDALVQRILYLEYLGFIQLPQALIAVPLHKSRLRQRGFNQAWLIAKALS
KRLDIPLVDNMLFRMKETQPQAGLSGRLRRKNLKGAFELSPEFNWQRVALIDDVVTTGTTVEEIAKLLQRKHTQVQVWCL
ARAEAPGRR

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=225, Percent_Identity=36, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 28213; Mature: 28213

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNNEKDFIISKTPWTRWLSAILPNRCLLCHQHIDSVNRGICSVCLHACRYQTPICLGC
CCCCCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
GGEMLISMAFCGHCMASTPLTVIAPCSYHHGLGHWVGQVKYQAQFAVIDVLVDALVQRIL
CHHHHHHHHHHHHHHHCCCEEEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLEYLGFIQLPQALIAVPLHKSRLRQRGFNQAWLIAKALSKRLDIPLVDNMLFRMKETQP
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
QAGLSGRLRRKNLKGAFELSPEFNWQRVALIDDVVTTGTTVEEIAKLLQRKHTQVQVWCL
CCCCCHHHHHHCCCCEEEECCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEE
ARAEAPGRR
EECCCCCCC
>Mature Secondary Structure
MKLNNEKDFIISKTPWTRWLSAILPNRCLLCHQHIDSVNRGICSVCLHACRYQTPICLGC
CCCCCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
GGEMLISMAFCGHCMASTPLTVIAPCSYHHGLGHWVGQVKYQAQFAVIDVLVDALVQRIL
CHHHHHHHHHHHHHHHCCCEEEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLEYLGFIQLPQALIAVPLHKSRLRQRGFNQAWLIAKALSKRLDIPLVDNMLFRMKETQP
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
QAGLSGRLRRKNLKGAFELSPEFNWQRVALIDDVVTTGTTVEEIAKLLQRKHTQVQVWCL
CCCCCHHHHHHCCCCEEEECCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEE
ARAEAPGRR
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]