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The map label for this gene is ctaD [H]

Identifier: 157963811

GI number: 157963811

Start: 4860695

End: 4862299

Strand: Direct

Name: ctaD [H]

Synonym: Spea_4000

Alternate gene names: 157963811

Gene position: 4860695-4862299 (Clockwise)

Preceding gene: 157963810

Following gene: 157963812

Centisome position: 93.93

GC content: 48.97

Gene sequence:

>1605_bases
ATGAGCACGATTACACAAGATTCACCAGCCGCTCACGACGATCACCATGATGACCATCATCATGGGGCGCCGAAAGGCAT
CATGCGCTGGATTTTAACCACCAATCACAAAGATATTGGTACGCTTTATTTATGGTTTAGCTTCATCATGTTCCTGACCG
GTGGCGCCATGGCAATGGTGATCCGTGCAGAACTGTTTCAACCGGGCCTACAGTTAGTCGAGCCCAACTTTTTTAACCAG
ATGACCACAGTCCATGGCTTAATCATGGTATTCGGTGCGGTAATGCCGGCCTTTACCGGCTTGGCTAACTGGTTAATTCC
GATGATGATTGGTGCGCCAGATATGGCGCTTCCGCGAATGAATAACTGGAGTTTTTGGATCCTACCTTTTGCATTTTCGA
TCTTGCTAAGCTCGCTATTTATGGAAGGAGGCGGGCCTAACTTTGGTTGGACCTTCTACGCGCCGTTATCGACAACCTAT
AGCCCTGACAGCACCGCATTATTTGTGTTTGCCGTTCACATAATGGGAATTAGCTCAATCATGGGTGCGATTAACGTGGT
TGTCACCATAGTTAATATGCGCGCGCCGGGCATGACTTGGATGAAACTACCGCTATTTGTATGGACCTGGTTAATTACTG
CATTTTTATTGATTGCCGTGATGCCCGTGCTTGCAGGTGTAGTCACCATGGTGCTGACAGATAAATACTTCGGCACTAGC
TTTTTCGATGCCGCTGGCGGCGGCGACCCTGTGATGTTCCAGCATATCTTCTGGTTCTTCGGCCACCCTGAAGTCTACAT
CATGATCTTGCCCTCTTTCGGCATTATCTCAGCGATTGTGCCCGCCTTTAGCCGCAAACGTCTATTTGGTTACTCCTCTA
TGGTTTATGCCACGGCGAGTATCGCAATCTTGTCGTTCTTGGTTTGGGCACACCACATGTTTACCACTGGCATGCCGGTA
TTTGCCGAGCTCTTCTTTATGTATTGCACCATGTTGATTGCGGTGCCCACCGGAGTAAAGGTGTTTAACTGGGTAGCGAC
TATGTGGAGAGGCTCGATCAGCTTCGAGACCCCCATGTTGTTTGCAGTGGCATTTATTATTTTGTTCACTATCGGCGGCT
TCTCAGGTTTGATGCTGGCGATTACTCCCGCGGACTTCCAGTACCATGATACCTACTTCGTAGTGGCGCATTTCCACTAT
GTGTTAGTCACCGGAGCCATATTCTCGATAATGGCGGCGGCCTATTACTGGCTACCAAAGTGGACGGGCAACATGTATAG
CGAAACATTAGGCCGCTGGCACTTCTGGTGTTCAGTTATTTCGGTGAACGTATTGTTCTTCCCAATGCATTTTCTTGGGC
TTGCGGGTATGCCACGACGGATCCCTGATTATGCGATTCAATTTGCCGATGTTAACCAGATAGTCTCCATCGGGGGATTT
GCTTTTGGTCTGTCGCAGCTGATTTTCTTAGCCGTGGTGATTAAATGTATTCGCGGTGGTGAGAAAGCGCCAGCTAAACC
GTGGGAAGGAGCCGAAGGTCTAGAATGGACAATACCAAGCCCCGCTCCCTATCACTCGTTTACTACGCCACCAGAGGTGA
AGTAA

Upstream 100 bases:

>100_bases
TGCCGCGGTCATTACTTTTGAACGCAACGCATGGGGTAATGACTCAGGAGATGCTGTGCAAGCTTCTGATGTTGATGGTC
ACGGAAAGTAGGGGATTAAC

Downstream 100 bases:

>100_bases
ACATGGCTGAGTTAAAGCGTAAATCCAATCGCAAACTGATCATAATGCTAATTATTGGCGCTGTGGGCATGTTTGGCTTT
GGATTTGCGCTTGTTCCTTT

Product: cytochrome c oxidase subunit I type

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MSTITQDSPAAHDDHHDDHHHGAPKGIMRWILTTNHKDIGTLYLWFSFIMFLTGGAMAMVIRAELFQPGLQLVEPNFFNQ
MTTVHGLIMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWSFWILPFAFSILLSSLFMEGGGPNFGWTFYAPLSTTY
SPDSTALFVFAVHIMGISSIMGAINVVVTIVNMRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGVVTMVLTDKYFGTS
FFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKRLFGYSSMVYATASIAILSFLVWAHHMFTTGMPV
FAELFFMYCTMLIAVPTGVKVFNWVATMWRGSISFETPMLFAVAFIILFTIGGFSGLMLAITPADFQYHDTYFVVAHFHY
VLVTGAIFSIMAAAYYWLPKWTGNMYSETLGRWHFWCSVISVNVLFFPMHFLGLAGMPRRIPDYAIQFADVNQIVSIGGF
AFGLSQLIFLAVVIKCIRGGEKAPAKPWEGAEGLEWTIPSPAPYHSFTTPPEVK

Sequences:

>Translated_534_residues
MSTITQDSPAAHDDHHDDHHHGAPKGIMRWILTTNHKDIGTLYLWFSFIMFLTGGAMAMVIRAELFQPGLQLVEPNFFNQ
MTTVHGLIMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWSFWILPFAFSILLSSLFMEGGGPNFGWTFYAPLSTTY
SPDSTALFVFAVHIMGISSIMGAINVVVTIVNMRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGVVTMVLTDKYFGTS
FFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKRLFGYSSMVYATASIAILSFLVWAHHMFTTGMPV
FAELFFMYCTMLIAVPTGVKVFNWVATMWRGSISFETPMLFAVAFIILFTIGGFSGLMLAITPADFQYHDTYFVVAHFHY
VLVTGAIFSIMAAAYYWLPKWTGNMYSETLGRWHFWCSVISVNVLFFPMHFLGLAGMPRRIPDYAIQFADVNQIVSIGGF
AFGLSQLIFLAVVIKCIRGGEKAPAKPWEGAEGLEWTIPSPAPYHSFTTPPEVK
>Mature_533_residues
STITQDSPAAHDDHHDDHHHGAPKGIMRWILTTNHKDIGTLYLWFSFIMFLTGGAMAMVIRAELFQPGLQLVEPNFFNQM
TTVHGLIMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWSFWILPFAFSILLSSLFMEGGGPNFGWTFYAPLSTTYS
PDSTALFVFAVHIMGISSIMGAINVVVTIVNMRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGVVTMVLTDKYFGTSF
FDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKRLFGYSSMVYATASIAILSFLVWAHHMFTTGMPVF
AELFFMYCTMLIAVPTGVKVFNWVATMWRGSISFETPMLFAVAFIILFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYV
LVTGAIFSIMAAAYYWLPKWTGNMYSETLGRWHFWCSVISVNVLFFPMHFLGLAGMPRRIPDYAIQFADVNQIVSIGGFA
FGLSQLIFLAVVIKCIRGGEKAPAKPWEGAEGLEWTIPSPAPYHSFTTPPEVK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=510, Percent_Identity=49.0196078431373, Blast_Score=445, Evalue=1e-125,
Organism=Escherichia coli, GI1786634, Length=514, Percent_Identity=39.8832684824903, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6226519, Length=530, Percent_Identity=47.5471698113208, Blast_Score=470, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=49.6913580246914, Blast_Score=312, Evalue=7e-86,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=45.9677419354839, Blast_Score=203, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59624; Mature: 59493

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTITQDSPAAHDDHHDDHHHGAPKGIMRWILTTNHKDIGTLYLWFSFIMFLTGGAMAMV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHH
IRAELFQPGLQLVEPNFFNQMTTVHGLIMVFGAVMPAFTGLANWLIPMMIGAPDMALPRM
HHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NNWSFWILPFAFSILLSSLFMEGGGPNFGWTFYAPLSTTYSPDSTALFVFAVHIMGISSI
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
MGAINVVVTIVNMRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGVVTMVLTDKYFGTS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKRLFGYSSMVYATAS
HHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHHH
IAILSFLVWAHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATMWRGSISFETPML
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHH
FAVAFIILFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYVLVTGAIFSIMAAAYYWLPK
HHHHHHHHHHHCCCCCEEEEEECCCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
WTGNMYSETLGRWHFWCSVISVNVLFFPMHFLGLAGMPRRIPDYAIQFADVNQIVSIGGF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEHHHHHHHHHHHHH
AFGLSQLIFLAVVIKCIRGGEKAPAKPWEGAEGLEWTIPSPAPYHSFTTPPEVK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STITQDSPAAHDDHHDDHHHGAPKGIMRWILTTNHKDIGTLYLWFSFIMFLTGGAMAMV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHH
IRAELFQPGLQLVEPNFFNQMTTVHGLIMVFGAVMPAFTGLANWLIPMMIGAPDMALPRM
HHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NNWSFWILPFAFSILLSSLFMEGGGPNFGWTFYAPLSTTYSPDSTALFVFAVHIMGISSI
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
MGAINVVVTIVNMRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGVVTMVLTDKYFGTS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKRLFGYSSMVYATAS
HHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHHH
IAILSFLVWAHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATMWRGSISFETPML
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHH
FAVAFIILFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYVLVTGAIFSIMAAAYYWLPK
HHHHHHHHHHHCCCCCEEEEEECCCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
WTGNMYSETLGRWHFWCSVISVNVLFFPMHFLGLAGMPRRIPDYAIQFADVNQIVSIGGF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEHHHHHHHHHHHHH
AFGLSQLIFLAVVIKCIRGGEKAPAKPWEGAEGLEWTIPSPAPYHSFTTPPEVK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]