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The map label for this gene is ctaC [H]

Identifier: 157963810

GI number: 157963810

Start: 4859111

End: 4860685

Strand: Direct

Name: ctaC [H]

Synonym: Spea_3999

Alternate gene names: 157963810

Gene position: 4859111-4860685 (Clockwise)

Preceding gene: 157963809

Following gene: 157963811

Centisome position: 93.9

GC content: 47.94

Gene sequence:

>1575_bases
GTGAAGCAATTGTTGTATAGTGTACTGGCGTTGCTATTTACGCCCGTGCTTGTTGCATCAGAAATGCCACTCAATATGAC
AGAGGGTGTGACGGATATCAGTAACAGGGTTTATAACCTGCACATGATTATTCTCTACATCTGCTGCGCTATTGGCATCT
TAGTATTTGGCGTAATGATTTATGCCATGATCAACCACCGCAAATCAAAAGGCGCAGTTGCCGCCAACTTTCATGAAAGT
ACTAAAGTCGAGATCCTGTGGACTATTGTACCTTTTATCATCTTGATACTTATGGCCATTCCCGCAACCAAAACATTGAT
TGCCATGGAAGACCCCAGTAATGCCGACCTAACGGTCAAGATCACTGGCTCACAGTGGAAATGGCATTACAGTTATTTCG
ATCAAGACATTGAGTTCTTCAGCCTATTATCGACACCGCGTGAACAGATAGATGGCGATGCAACCAAAGGCGAAAACTAC
CTGTTAGAGGTAGATAAGCCCTTGGTTTTACCTATCAATCGCAAGGTACGTTTCTTAATGACCTCAGAAGATGTTATCCA
CTCCTGGTGGGTGCCCGCTTTTGCTGTGAAAAAAGATGCCAATCCGGGATTTATTAATGAGGCGTGGACCCGCATCGACA
AGCCCGGCACATACCGAGGTCAATGCGCAGAGCTCTGCGGTAAAGACCACGGCTTTATGCCGATTGTAGTGGAAGCACTA
TCGGAAGAGGATTTCGATGCCTGGCTAATCACTCAGCAACAACACGCGCAAAATGCTGAAGCGGCAGCTAAGACTGCTTT
ATCGCAAACCTTGACCATGGAAGAGTTAATGGCTCAAGGTGAGCAAGTCTACCTAGCAAGGTGTGCAGCTTGTCACCAAC
CTAACGGGGCAGGCCTTCCAGGTGTATTCCCATCCCTTATTGGCAGCCCGATAATTAAAGGAGCGGTAGCCAGCCATGTA
GATATTGTTGTAAACGGTAAACCCGGCACCGCAATGCAAGCGTTTGCAAAACAGCTAACGGCCACAGAAATCGCTGCCGT
GGTGACCTTCGAGCGGAATGCTTGGGGTAATGATTCTGGCGATATGATCCAAGCTTCGGATATCGACTCGGGGAGTTCAA
CGCCTGCGGCATCTGATGACTCAGACACAGCAATTGCCACCACATTACCGGCAACGTTACCTGAAACCCAGCAAGCAGAC
ATACCGGCAACCGAGACTGTCGTAGAAGTGACTGAAGATGTTAAAGCCGTTGTTTTAGATGACTTAACTATGGATGAATT
GATGACCATGGGTGAGAAGGTCTATATGACTAGCTGTATTGCTTGTCACCAAGCCACTGGCGCTGGCTTACCACCAGCTT
TCCCGTCATTGGTTGCGAGCCCGATTATCAAAGGACCTGTTTCAGACCACCTTGAGATGGTCATTAATGGTAAGCCTGGC
ACGGCGATGCAAGCGTTTGGTCAACAGCTCACTCCTCAAGAAATTGCCGCGGTCATTACTTTTGAACGCAACGCATGGGG
TAATGACTCAGGAGATGCTGTGCAAGCTTCTGATGTTGATGGTCACGGAAAGTAG

Upstream 100 bases:

>100_bases
CTTTGAAGTCATCGTTGCTTTTTTGGGAACTGAAGAGTTTACATAGAGCAGAGACTTACTGTGTGACTCTTCTTTGTCTT
GCTGACAGAGGAGAAGTCTA

Downstream 100 bases:

>100_bases
GGGATTAACATGAGCACGATTACACAAGATTCACCAGCCGCTCACGACGATCACCATGATGACCATCATCATGGGGCGCC
GAAAGGCATCATGCGCTGGA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MKQLLYSVLALLFTPVLVASEMPLNMTEGVTDISNRVYNLHMIILYICCAIGILVFGVMIYAMINHRKSKGAVAANFHES
TKVEILWTIVPFIILILMAIPATKTLIAMEDPSNADLTVKITGSQWKWHYSYFDQDIEFFSLLSTPREQIDGDATKGENY
LLEVDKPLVLPINRKVRFLMTSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGTYRGQCAELCGKDHGFMPIVVEAL
SEEDFDAWLITQQQHAQNAEAAAKTALSQTLTMEELMAQGEQVYLARCAACHQPNGAGLPGVFPSLIGSPIIKGAVASHV
DIVVNGKPGTAMQAFAKQLTATEIAAVVTFERNAWGNDSGDMIQASDIDSGSSTPAASDDSDTAIATTLPATLPETQQAD
IPATETVVEVTEDVKAVVLDDLTMDELMTMGEKVYMTSCIACHQATGAGLPPAFPSLVASPIIKGPVSDHLEMVINGKPG
TAMQAFGQQLTPQEIAAVITFERNAWGNDSGDAVQASDVDGHGK

Sequences:

>Translated_524_residues
MKQLLYSVLALLFTPVLVASEMPLNMTEGVTDISNRVYNLHMIILYICCAIGILVFGVMIYAMINHRKSKGAVAANFHES
TKVEILWTIVPFIILILMAIPATKTLIAMEDPSNADLTVKITGSQWKWHYSYFDQDIEFFSLLSTPREQIDGDATKGENY
LLEVDKPLVLPINRKVRFLMTSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGTYRGQCAELCGKDHGFMPIVVEAL
SEEDFDAWLITQQQHAQNAEAAAKTALSQTLTMEELMAQGEQVYLARCAACHQPNGAGLPGVFPSLIGSPIIKGAVASHV
DIVVNGKPGTAMQAFAKQLTATEIAAVVTFERNAWGNDSGDMIQASDIDSGSSTPAASDDSDTAIATTLPATLPETQQAD
IPATETVVEVTEDVKAVVLDDLTMDELMTMGEKVYMTSCIACHQATGAGLPPAFPSLVASPIIKGPVSDHLEMVINGKPG
TAMQAFGQQLTPQEIAAVITFERNAWGNDSGDAVQASDVDGHGK
>Mature_524_residues
MKQLLYSVLALLFTPVLVASEMPLNMTEGVTDISNRVYNLHMIILYICCAIGILVFGVMIYAMINHRKSKGAVAANFHES
TKVEILWTIVPFIILILMAIPATKTLIAMEDPSNADLTVKITGSQWKWHYSYFDQDIEFFSLLSTPREQIDGDATKGENY
LLEVDKPLVLPINRKVRFLMTSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGTYRGQCAELCGKDHGFMPIVVEAL
SEEDFDAWLITQQQHAQNAEAAAKTALSQTLTMEELMAQGEQVYLARCAACHQPNGAGLPGVFPSLIGSPIIKGAVASHV
DIVVNGKPGTAMQAFAKQLTATEIAAVVTFERNAWGNDSGDMIQASDIDSGSSTPAASDDSDTAIATTLPATLPETQQAD
IPATETVVEVTEDVKAVVLDDLTMDELMTMGEKVYMTSCIACHQATGAGLPPAFPSLVASPIIKGPVSDHLEMVINGKPG
TAMQAFGQQLTPQEIAAVITFERNAWGNDSGDAVQASDVDGHGK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=168, Percent_Identity=39.2857142857143, Blast_Score=139, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6226540, Length=232, Percent_Identity=31.4655172413793, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 56661; Mature: 56661

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLLYSVLALLFTPVLVASEMPLNMTEGVTDISNRVYNLHMIILYICCAIGILVFGVMI
CHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAMINHRKSKGAVAANFHESTKVEILWTIVPFIILILMAIPATKTLIAMEDPSNADLTVK
HHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEE
ITGSQWKWHYSYFDQDIEFFSLLSTPREQIDGDATKGENYLLEVDKPLVLPINRKVRFLM
EECCCEEEEHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEECCCEEEECCCCEEEEE
TSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGTYRGQCAELCGKDHGFMPIVVEAL
ECHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHH
SEEDFDAWLITQQQHAQNAEAAAKTALSQTLTMEELMAQGEQVYLARCAACHQPNGAGLP
CCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
GVFPSLIGSPIIKGAVASHVDIVVNGKPGTAMQAFAKQLTATEIAAVVTFERNAWGNDSG
CHHHHHHCCHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCC
DMIQASDIDSGSSTPAASDDSDTAIATTLPATLPETQQADIPATETVVEVTEDVKAVVLD
CEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
DLTMDELMTMGEKVYMTSCIACHQATGAGLPPAFPSLVASPIIKGPVSDHLEMVINGKPG
CCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCC
TAMQAFGQQLTPQEIAAVITFERNAWGNDSGDAVQASDVDGHGK
HHHHHHCCCCCHHHEEEEEEEECCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MKQLLYSVLALLFTPVLVASEMPLNMTEGVTDISNRVYNLHMIILYICCAIGILVFGVMI
CHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAMINHRKSKGAVAANFHESTKVEILWTIVPFIILILMAIPATKTLIAMEDPSNADLTVK
HHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEE
ITGSQWKWHYSYFDQDIEFFSLLSTPREQIDGDATKGENYLLEVDKPLVLPINRKVRFLM
EECCCEEEEHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEECCCEEEECCCCEEEEE
TSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGTYRGQCAELCGKDHGFMPIVVEAL
ECHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHH
SEEDFDAWLITQQQHAQNAEAAAKTALSQTLTMEELMAQGEQVYLARCAACHQPNGAGLP
CCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
GVFPSLIGSPIIKGAVASHVDIVVNGKPGTAMQAFAKQLTATEIAAVVTFERNAWGNDSG
CHHHHHHCCHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCC
DMIQASDIDSGSSTPAASDDSDTAIATTLPATLPETQQADIPATETVVEVTEDVKAVVLD
CEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
DLTMDELMTMGEKVYMTSCIACHQATGAGLPPAFPSLVASPIIKGPVSDHLEMVINGKPG
CCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCC
TAMQAFGQQLTPQEIAAVITFERNAWGNDSGDAVQASDVDGHGK
HHHHHHCCCCCHHHEEEEEEEECCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA